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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Folia Medica Indonesiana JMM (Jurnal Masyarakat Mandiri) Window of Health : Jurnal Kesehatan Jurnal Epidemiologi Kesehatan Komunitas AGRITEKNO, Jurnal Teknologi Pertanian Jurnal Medika Malahayati Jurnal Pengabdian Dharma Laksana Jurnal Kesehatan Terpadu (Integrated Health Journal) Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Pengabdian kepada Masyarakat Molucca Medica Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Jurnal PADE: Pengabdian & Edukasi PAMERI : Pattimura Medical Review Bioactivities Jurnal Kesehatan Masyarakat
Tahitu, Ritha
Fakultas Kedokteran Universitas Pattimura
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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Journal : Bioactivities

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In Vitro Antibacterial Activity and Phytochemical Screening of Galoba (Hornstedtia alliaceae) Seeds Extract Melfan El Shaday Sule; Eka Astuty; Ritha Tahitu
Bioactivities Vol. 1 No. 2 (2023): Bioactivities
Publisher : Pandawa Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47352/bioactivities.2963-654X.196

Abstract

Hornstedtia alliacea has been traditionally used by indigenous people for a variety of medicinal purposes. This study aimed to determine the antibacterial activity of ethanol extracts of Galoba seeds (Hornstedtia alliacea) against standard bacterial cultures of Staphylococcus aureus (ATCC-29213) and Escherichia coli (FNCC-6183) using Kirby-Bauer disk diffusion method. The phytochemical tests were carried out to determine the presence of active substances which are antibacterial in the results of the extraction. The color intensity or the precipitate formation was used as analytical response to these tests. The major phytochemical constituents identified in galoba seeds ethanol extracts were tannins, flavonoids, saponins, quinones, and steroids. The antibacterial assay showed that galoba seed extract inhibited the growth of S. aureus and E. coli. The diameter of the inhibition zone increased as the extract concentration increased. The largest inhibition zone for S. aureus was at a concentration of 100% with a diameter of 20.93 mm and the largest inhibition zone for E. coli was at a concentration of 100% with a diameter of 18.05 mm. The results of this study indicated that the plant contains some major bioactive compounds that inhibit the growth of microorganisms, thereby showing great potency as an effective source of drugs. The phytochemical analysis also reveals that the plant contains similar constituents useful for medicinal purposes.
Co-Authors Abbas, Mutmainnah Amanda Gracia Manuputty Ardianto, Anggih Cipta Ayu Betzia Mangosa Bandjar, Fitri Kadarsih Bertha Jean Que Christiana R Titaley Christiana Rialine Titaley Christiana Rialine Titaley Christiana Rialine Titaley Dewi Aryanti M. Rusdin Djoko, Sri Wahyuni Eka Astuty Eka Astuty Elpira Asmin Elpira Asmin Hana Jamaludin Hasibuan, Andrian Bayo Arif Hataul, Is Asma’ul Haq Hehanussa, Zubaidah Juniler Rumahloine Kailola, Nathalie E. Kamoda, Tri Puspa Rini Dusung Kusadhiani, Indrawanti Lapu, Petrus Liyani Sartika Sara Loppies, Cindy R M Loppies, Cindy RM, Mailera, Damara Herlis Mainase, Josepina Malakauseya, Maxwell Landri Vers Malawat, Healdatia R. Melda Yunita Melfan El Shaday Sule Merlin M Maelissa Metekohy, Meilani Muhammad Zaid Wakano Mus, Rosdiana Nadya R. J. Riry Nahumarury, Salmin Nathalie E Kalilola Nathalie Kailola Pagaya, Joseph Pangestu, Juan Felix Paringotan Y Silalahi Pelupessy, Thesia Pormes, Debora Rahmadani, Gita Ramla, Razita Ratu, Ricky N.D.C Ratu1 Roni, Syamsah Ruth Magdalena Lumbantobing Saptenno, Lidya Sara, Liyani S. Savitri, Imelda K E Seimahuira, Theresia Setha, Beni Shafira Chairani Chatib Soumena, Rifah Zafarani Suay Anabella Wattimena Syamsah Roni Tanamal, Rita Tando, Yudhie D. Taufik Zuneldi Thesia Pelupessy Titaley, Christiana R. Titaley, Christiana Rialine van Affelen, Zadrach Vanessa Tjandi Vebiyanti Tentua Wael, Bela M. Warella, Juen Carla Yudhie Djuhastidar Tando Yudhie Djuhastidar Tando Yulia, Ceriana Putri Zawawi, Wa Ode Meutya Zuneldi, Taufik