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All Journal Agroland : Jurnal Ilmu-Ilmu Pertanian Journal of Politic and Government Studies Jurnal Kata: Bahasa, Sastra, dan Pembelajarannya Pro-Life CERMIN: Jurnal Penelitian SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Jurnal Ekonomi Kolaborasi Jurnal Pengabdian Masyarakat Berdikari : Jurnal Pengabdian kepada Masyarakat Pharmacy Action Journal Journal of Global Pharma Technology Journal of Sustainable Community Development Jurnal Edukasi Sebelas April TA’AWUN: Jurnal Pengabdian
Ria Anggraeni
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Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Civil Engineering, Building, Construction & Architecture Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Journal : SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL

 1 
DRUG THERAPY IN PATIENTS WITH GRADE 4 DEXTRA HIP OSTEOARTHRITIS WITH COMORBID HYPERTENSION AND TYPE 2 DIABETES MELLITUS Astiani, Rangki; Piter, Piter; Anggraeni, Ria; Luthfiana, Farisa; Sari, Dini Permata; Ramatillah, Diana Laila; Khan, Khasif
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 10, No 2 (2025)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v10i2.8977

Abstract

Osteoarthritis (OA) is a chronic degenerative disease that affects the joints, especially heavy joints such as the knees and hips. OA often causes chronic pain and limited mobility, which is even more complex when accompanied by comorbid hypertension and type 2 diabetes mellitus. These comorbidities increase the risk of pharmacotherapy side effects and drug interactions, requiring a multidisciplinary approach and careful clinical pharmacy monitoring. The purpose of this report is to review the pharmacotherapy management of grade 4 OA Hip Dextra with comorbid HT and DMT2, assessing the safety, effectiveness, and role of clinical pharmacists in therapy optimization. A retrospective case study was conducted by analyzing the patient's medical records, including anamnesis, physical examination, laboratory, pharmacological therapy, and clinical response. The analysis was conducted based on the national guidelines of the Indonesian Ministry of Health, the 2021 National Formulary, PERKENI 2023, and PAPDI 2021. The patient was given combination therapy of NSAIDs, analgesics, prophylactic antibiotics, muscle relaxants, gastric protection, and supplementation for anemia. Therapeutic adjustments were made according to the patient's response and laboratory parameters. Clinical pharmacy monitoring ensures pain control, mobility, hemoglobin, and blood sugar. A multidisciplinary approach based on national guidelines has been shown to improve the safety and effectiveness of OA therapy with multiple comorbidities.
Identifikasi Potentially Inappropriate Medication (PIM) Pada Pasien Geriatri : Review Artikel Ilmiah Anggraeni, Ria; melasari, wulan panduwi
SOCIAL CLINICAL PHARMACY INDONESIA JOURNAL Vol 10, No 1 (2025)
Publisher : Universitas 17 Agustus 1945 Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52447/scpij.v10i1.9136

Abstract

Pasien geriatri memiliki kerentanan tinggi terhadap kejadian Potentially Inappropriate Medication (PIM) akibat perubahan fisiologis terkait usia, tingginya prevalensi penyakit kronis, dan praktik polifarmasi. Kejadian PIM dapat meningkatkan risiko efek samping obat, interaksi obat, serta luaran klinis yang merugikan. Review artikel ilmiah ini bertujuan untuk mengidentifikasi kejadian PIM, pola obat yang paling sering terlibat, serta faktor risiko yang berkontribusi terhadap terjadinya PIM pada pasien geriatri berdasarkan berbagai penelitian yang menggunakan kriteria eksplisit, khususnya Beers Criteria dan STOPP Criteria. Metode yang digunakan adalah narrative review dengan menelaah artikel penelitian nasional terkait PIM pada pasien geriatri di berbagai pelayanan kesehatan. Hasil telaah menunjukkan bahwa prevalensi PIM pada pasien geriatri masih tergolong tinggi dengan variasi yang dipengaruhi oleh perbedaan karakteristik pasien dan metode identifikasi. Obat yang paling sering teridentifikasi sebagai PIM meliputi antihipertensi tertentu, diuretik, benzodiazepin, NSAID, metoclopramide, PPI dan kortikosteroid. Faktor yang konsisten berhubungan dengan kejadian PIM adalah polifarmasi, jumlah komorbiditas, serta lama perawatan. Kesimpulan dari review ini menegaskan bahwa PIM masih menjadi permasalahan klinis yang signifikan pada pasien geriatri. Oleh karena itu, diperlukan evaluasi peresepan dan skrining PIM secara rutin sebagai upaya meningkatkan keamanan dan rasionalitas terapi obat pada populasi geriatri.
Co-Authors Abdul Hadid Ali Mustofa Astiani, Rangki Azzahra, Taysa Zifa Candrawargani, Devy Tri Dwinanda R, Elvira Dzunuwanus Ghulam Manar Farisa Luthfiana Fauziyah, Eni Handayani, Yosi Hasanah, Afrianti Hidayat, Hajan Iffah Febri Anti Fitriyatul Lailiyah Irawati, Juwita Ismail Hadisoebroto Dilogo Jeanne Adiwinata Pawitan Kahfie Nazaruddin Khan, Khasif Khusniah, Riza Kuswara Lauhul Mahfudz M. Agus Santso Marliana Sri Rejeki Melasari, Wulan Panduwi Miftakhur Rohmah, Miftakhur Muhammad Zainuddin Muslim Ansori nadya nur khodhizah Nuryati, Ida Oktaria, Hanny piter, piter Pratama, Muhammad Meidiansyah Priyatno Harsasto Putri, Ella Wiyasa Putri, Nikita Dwi Utami Prima Putri, Zaskia Fahmi Ramatillah, Diana Laila Ravita D, Nena Rento Eko Fenti Indri A. Resmi, Juniar Kalpika Sagala, Zuraida Sari, Dini Permata Sari, Yessy Nur Endah Seto Sulaksono Adi Wibowo, Seto Sulaksono Adi Sinaga, Inggrid Wahyuni Sinarti, Sinarti Slamet Subagyo, Slamet Starifulkani Arif Suhartin, Suhartin Syamsuddin Laude Theodorus Rexa Handoyo Wawaimuli Arozal Winarti, Lilik Wirawan, Adhitomo Yati Sumiyati Yogi Ismail Gani Zahira, Rayzha Firya