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All Journal Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Jurnal Pemberdayaan Masyarakat Madani (JPMM) Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Jurnal SOLMA JSFK (Jurnal Sains Farmasi & Klinis) FITOFARMAKA: Jurnal Ilmiah Farmasi PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JFIOnline Jurnal Ilmu Kefarmasian Indonesia Jurnal Jamu Indonesia Borneo Journal Of Pharmascientech Jurnal Locus Penelitian dan Pengabdian Pharmaceutical Sciences and Research (PSR) Jurnal Sains dan Kesehatan Damhil: Jurnal Pengabdian kepada Masyarakat Indonesian Journal of Jamu Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Rini Prastiwi
Fakultas Farmasi Dan Sains, Universitas Muhammadiyah Prof. Dr. HAMKA
Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Mathematics Medicine & Pharmacology Public Health Social Sciences Other

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Edukasi Penggunaan Obat Rasional di Kampung Tok Kassim, Changlun, Kedah Syafitri, Yeshaira Zahra Shabira; Widayanti, Ari; Prastiwi, Rini; Amirullah, Gufron
Damhil: Jurnal Pengabdian kepada Masyarakat Vol 3, No 2: December 2024
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37905/damhil.v3i2.27396

Abstract

Rational drug use is a crucial aspect of medication management that requires a thorough understanding to ensure that treatment regimens are appropriately tailored to meet the individual needs of patients, administered within the correct timeframes, and remain affordable. When drug use is irrational, it can result in serious health consequences such as organ damage, the development of drug resistance, and in severe cases, even death. To address this, it is vital to enhance awareness about the importance of rational drug use and its benefits. In Tok Kassim Village, several health services were provided, including comprehensive blood sugar, blood pressure, and cholesterol checks, as well as interactive discussions and a question-and-answer session with the local residents. These activities revealed that the average villager uses medication to manage cholesterol levels, hypertension, and blood sugar. The interactive discussions and question-and-answer sessions were particularly effective and smooth because the villagers demonstrated a good understanding of the principles of rational drug use, highlighting the positive impact of the educational efforts in reinforcing the significance of proper medication management.
Community Empowerment Through the Enhancement of Entrepreneurship in the Production of Lotion and Mosquito Spray for Dengue Fever in Sukmajaya, Depok Prastiwi, Rini; Dewanti, Ema; Rahayu, Dewi Pudji; Ladeska, Vera; Wardani, Elly
Jurnal Pemberdayaan Masyarakat Madani (JPMM) Vol. 8 No. 2 (2024): Jurnal Pemberdayaan Masyarakat Madani (JPMM) (DOAJ & SINTA 3 Indexed)

Publisher : Fakultas Ekonomi dan Bisnis Universitas Negeri Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21009/JPMM.008.2.13

Abstract

Dengue fever has become one of the endemic diseases in the Sukmajaya area of Depok. This disease can claim the lives of up to 10% of those affected. Community empowerment, particularly through the empowerment of PKK groups. This community service aims to increase the community's ability to prevent the spread of the Aedes aegypti mosquito through empowering the PKK group community. It can prevent the spread of mosquitoes by introducing natural materials as mosquito repellents and creating lotion and spray products as alternative solutions. The program involves training and assistance in producing lotions and sprays using natural ingredients. Using essential oils as raw materials, along with marketing techniques, can be a solution to address this issue. The Community Service Team of the Faculty of Pharmacy and Science (FFS) UHAMKA and the Faculty of Economics and Business (FEB) UHAMKA provided comprehensive training and guidance in the pharmacy skills program. Participants were instructed on creating lotion and mosquito repellent spray formulations using natural ingredients, including orange leaf extract, orange oil, lavender oil, and clove oil. The training consisted of lectures followed by a hands-on workshop on entrepreneurship, focusing on the importance of selecting appropriate packaging and promoting the products effectively. Participants are very enthusiastic about acquiring this skill because it enhances the capabilities of PKK administrators in utilizing natural materials in forms that will later boost the spirit of entrepreneurship and help prevent dengue fever.
Aktivitas Antiinflamasi Ekstrak Etanol 96% Batang Apel Beludru (Diospyros Blancoi A.Dc.) terhadap Jumlah Limfosit, Monosit, dan Neutrofil pada Tikus Putih Jantan Galur Wistar yang Diinduksi Karagenan: Antiinflammatory Activity of 96% Ethanol Extract of Apel Beludru Stems (Diospyros Blancoi A.Dc.) to the Number of Lymphocytes, Monocytes, and Neutrophils in Carrageenan-induced Wistar Rats Rusdi, Numlil Khaira; Bariroh, Tahyatul; Isra, Rafiq Al; Rahmat, Amalia; Fujianti, Fujianti; Prastiwi, Rini; Sunaryo, Hadi; Hariyanti, Hariyanti
Jurnal Sains dan Kesehatan Vol. 7 No. 4 (2025): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v7i4.2437

Abstract

The potential of velvet apple plants (Diospyros blancoi A. DC) is large, further research is still needed to determine the anti-inflammatory effect on velvet apple stems (Diospyros blancoi A. DC). The purpose of this study was to determine the anti-inflammatory activity of 96% ethanol extract of velvet apple stems against the reduction of lymphocytes, monocytes, and neutrophils. A total of 25 male white rats of wistar strain were divided into 5 groups, namely the negative control group, the positive control group (Na diclofenac), the group given 96% ethanol extract of velvet apple stems with several doses, namely doses of 125 mg / kg BB, 250 mg / kg BB and 500 mg / kg BB. All test animals were made air bags on days 1 and 3, then on day 6 test preparations and carrageenan induction were carried out. On the 7th day blood was taken through the retroorbital sinuses, then the calculation of lymphocytes, monocytes, neutrophils using a microscope was carried out and the data were analyzed using One-way Anova and Kruskal Wallis test. The results showed a higher percentage of negative lymphocytes, monocytes, and neutrophils compared to the treatment group. In the treatment group, the dose of 500mg/kgBB had a significant decrease in the percentage of lymphocytes, monocytes, neutrophils compared to the negative group (p<0.05) and was not significantly different from the positive control group. Ethanol extract 96% velvet apple stem dose 500 mg/kg body weight has the greatest anti-inflammatory activity against decreasing the percentage of lymphocytes, monocytes, and neutrophils. Keywords:          anti-inflammatory, apel beludru, Diospyros blancoi A. DC, lymphosite, monosite, neutrophil   Abstrak Potensi tanaman apel beludru (Diospyros blancoi A. DC) yang besar, sehingga perlu penelitian lebih lanjut untuk mengetahui efek antiinflamasi pada batang apel beludru (Diospyros blancoi A. DC). Tujuan penelitian ini untuk mengetahui aktivitas antiinflamasi ekstrak etanol 96% batang apel beludru terhadap penurunan limfosit, monosit, dan neutrofil. Sebanyak 25 ekor Tikus putih jantan galur wistar dibagi menjadi 5 kelompok yaitu kelompok kontrol negatif, kelompok kontrol positif (Na diklofenak), kelompok yang diberi ekstrak etanol 96% batang apel beludru dengan beberapa dosis yaitu dosis 125 mg/kgBB, 250 mg/kgBB dan 500 mg/kgBB. Semua hewan uji dibuat kantung udara pada hari ke-1 dan ke-3, lalu pada hari ke-6 dilakukan pemberian sediaan uji dan induksi karagenan. Pada hari ke-7 diambil darah melalui sinus retroorbitalis, kemudian dilakukan perhitungan sel limfosit, monosit, dan neutrofil menggunakan mikroskop. Data dianalisis menggunakan One-way Anova dan uji Kruskal Wallis. Hasil penelitian menunjukkan jumlah limfosit, monosit, dan neutrophil kelompok kontrol negatif lebih tinggi dibandingkan dengan kelompok perlakuan. Pada kelompok perlakuan, pemberian ekstrak dosis 500mg/kgBB mengalami penurunan persentase jumlah limfosit, monosit, neutrofil terbesar secara signifikan dibandingkan kelompok negatif (p<0,05) dan tidak berbeda bermakna dengan kelompok kontrol positif. Ekstrak etanol 96% batang apel beludru dosis 500 mg/kg BB memiliki aktivitas antiinflamasi terbesar terhadap penurunan persentase jumah limfosit, monosit, dan neutrophil. Kata Kunci:         antiinflamasi, apel beludru (Diospyros blancoi A. DC), limfosit, monosit, neutrophil
Aktivitas Imunomodulator Ekstrak n-Heksana, Etil Asetat, dan Metanol Biji Jinten Hitam (Nigella sativa L.) Prastiwi, Rini; ., Kisrini; Iqbal, Anwar; Kristi, Aprina
Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Vol. 2 No. 2 (2015)
Publisher : Faculty of Pharmacy, Widya Mandala Surabaya Catholic University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33508/jfst.v2i2.724

Abstract

Jinten hitam (Nigella sativa L.) adalah tanaman yang memiliki aktivitas imunomodulator. Kandungan biji jinten hitam adalah minyak atsiri, alkaloid, saponin, tanin, polifenol dan minyak lemak. Penelitian bertujuan untuk mengetahui efek imunomodulator ekstrak biji jinten hitam dengan parameter fagositosis makrofag dan peningkatan imunoglobulin G. Penelitian menggunakan 30 ekor mencit balb/c yang dibagi ke dalam 6 kelompok. Kelompok I diberi ekstrak n-heksana dengan dosis 1,6843 mg/20 gBB, kelompok II diberi eksrak etil astat dosis 0,2682 mg/20 gBB, kelompok III diberi eksrak metanol dosis 0,4272 mg/20 gBB, kelompok IV kontrol positif menggunakan Imboost® dosis 0,065 mg/20 gBB, kelompok V diberi CMC 0,5%, dan kelompok VI kontrol negatif siklofosfamid dosis 2 mg/20gBB. Ekstrak diberikan selama 21 hari, hari ke-7 dan hari ke-14 masing-masing mencit diinjeksikan SRBC (Sheep Red Blood Cells) intraperitoneal. Pada hari ke-21 darah mencit diambil untuk diambil serumnya, kemudian kadar IgG diperiksa dengan ELISA reader. Fagositosis makrofag dilihat berdasarkan aktivitas dan kapasitas makrofag dari sediaan apus cairan intraperitoneal, dengan menghitung persentase 100 makrofag yang melakukan fagositosis. Kapasitas fagositosis ditetapkan berdasarkan jumlah lateks yang difagositosis oleh 50 makrofag aktif. Hasil yang didapatkan ekstrak biji jinten hitam memiliki potensi sebagai imunomodulator dan ekstrak n-heksana memiliki potensi yang tinggi sebagai imunostimulator diban-dingkan ekstrak lain dengan hasil rata-rata presentasi aktivitas fagositosis makrofag 89,5% dan kapasitas fagositosis makrofag 1204 lateks, begitu juga hasil dengan uji IgG. Kata kunci: jinten hitam, imunomodulator, IgG, makrofag.
Pemanfaatan Bahan Alam untuk Pembuatan Foot Care di SMK Batik 1 Surakarta: Use of Natural Materials for Making Foot Care at Batik 1 Vocational School Surakarta Prastiwi, Rini; Dewanti, Ema; Ladeska, Vera; Sunaryo, Hadi
PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Vol. 9 No. 6 (2024): PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/pengabdianmu.v9i6.6819

Abstract

Improving entrepreneurship skills is very important in the current state of the COVID-19 pandemic. The number of layoffs carried out by the industrial world is one of the reasons for the high number of layoffs now. Entrepreneurial skills are an important part of educating school children from the start so that after graduation they are expected to open up job opportunities for themselves and others. Vocational High School (SMK) is now one of the schools that can produce skilled and innovative personnel. One of the private vocational schools in Surakarta that is trying to do that is SMK BATIK 1. The UHAMKA FFS Service Team provides training and guidance on the pharmacy expertise program to make foot care preparations, in the form of foot sanitizer and foot lotion. Preparations made from natural ingredients lemongrass extract, ginger extract, and coffee extract. Activities include lectures and workshops. Activities provide benefits in the form of increasing the soft skills and hard skills of students in utilizing natural materials in dosage forms which will increase the selling value.
UJI AKTIVITAS EKSTRAK ETANOL 96% BUAH STROBERI TERHADAP PENINGKATAN MEMORI SPASIAL PADA TIKUS MODEL DEMENSIA Khalishatunnada, Khalishatunnada; Sunaryo, Hadi; Prastiwi, Rini
Jurnal Locus Penelitian dan Pengabdian Vol. 2 No. 8 (2023): Jurnal Locus Penelitian dan Pengabdian
Publisher : Riviera Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58344/locus.v2i8.1587

Abstract

Buah stroberi (Fragaria x ananassa (Duchesne ex Weston) Duchesne ex Rozier) merupakan salah satu tanaman yang tinggi akan kandungan antioksidan salah satunya ialah flavonoid. Dari kandungannya tersebut diduga buah stroberi ini memiliki aktivitas sebagai antidemensia dengan meningkatkan memori spasial. Tujuan penelitian ini adalah untuk membuktikan aktivitas ekstrak etanol 96% buah stroberi sebagai antidemensia yang diinduksi ECS (Elektroconvulsive shock) dengan menggunakan metode pengujian T-maze.Penelitian ini menggunakan metode induksi demensia yang menggunakan aliran listrik dengan tegangan 210 mA selama 0,5 detik untuk tikus. Subjek dalam pengujian ini adalah tikus putih jantan (Rattus norvegicus) galur Sparague dawley berumur 2 - 3 bulan sebanyak 24 ekor yang terbagi menjadi 6 kelompok. Kelompok I (kelompok kontrol normal), kelompok II (kelompok kontrol negatif), kelompok III (kelompok kontrol positif), kelompok IV (dosis uji ekstrak 85 mg/200 g BB), kelompok V (dosis uji ekstrak 170 mg/200 g BB), kelompok VI (dosis uji ekstrak 340 mg/200 g BB) yang diberikan secara peroral. Data hasil kinerja memori spasial pada T-Maze 3 selama 7 hari dianalisa secara statistik menggunakan SPSS 20 dengan uji ANOVA oneway untuk mengetahui apakah ada pengaruh perlakuan pada kelompok dan dilanjutkan uji Tukey HSD untuk mengetahui apakah setiap perlakuan berbeda secara statistik atau tidak. Dari hasil penelitian menunjukkan bahwa pemberian ekstrak etanol 96% buah stroberi mempunyai pengaruh secara bermakna terhadap peningkatan memori spasial tikus putih jantan dengan nilai Sig = 0,000 (< 0,05).  
Activity of Ethanol Fraction of Luffa Acutangula (L.) Roxb. on Cholesterol Reduction in Dyslipidemic Hamster Viviandhari, Daniek; Prastiwi, Rini; Puspitasari, Elva Fitriani; Perdianti, Pegi
Jurnal Jamu Indonesia Vol. 5 No. 2 (2020): Jurnal Jamu Indonesia
Publisher : Tropical Biopharmaca Research Center, IPB University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/jji.v5i2.171

Abstract

National data shows the prevalence of coronary heart disease is 3,6%. The prevalence of dyslipidemia is around 35,9%. Dyslipidemia has a causal relationship with cardiovascular disease. Based on previous research, 70% ethanolic extract of Ridge Gourd has been shown to have antihyperlipidemic activity. This study aimed to study the activity of 70% ethanolic extract fraction of Ridge Gourd in decreasing the levels of total cholesterol, low-density lipoprotein (LDL-C), and triglycerides in hyperlipidemic hamsters. A total of 32 hamster were divided into 8 groups. Negative control, normal control, positive control (using atorvastatin dose 1,24 mg/kg body weight), positive control (fenofibrate dose 12,35 mg/kg body weight), ethyl acetate fraction, n-hexane fraction, water fraction (fraction doses 36,75 mg/kg body weight), and ethanol extract group (extract dose of 240 mg/kg body weight). The results showed that fraction group (n-hexane, ethyl acetate, water) and ethanol extract group experienced a decrease in total cholesterol, LDL-C, and triglycerides levels. Statistical analysis with one-way ANOVA showed an effect on the treatment given (p = 0,005). Tukey's test showed that ethyl acetate fraction group had an effect comparable to positive control with a decrease in total cholesterol, LDL-C, and triglycerides level by 56,03%, 52,14%, and 59,51% consecutively. Ethyl acetate fraction (doses 36,75 mg/kg body weight) was the most effective fraction in reducing total cholesterol, LDL-C, and triglycerides.
Co-Authors Agistananda, Banna Amalia, Mega Putri Rizky Amirullah, Gufron Anggraini, Ita Ari Widayanti Bariroh, Tahyatul Chusun Chusun Chusun, Chusun Daniek Viviandari Daniek Viviandhari Dewi Pudji Rahayu Diana, Popi Dyah Susilowati Elly Wardani, Elly Elva Fitriani Puspitasari Ema Dewanti Ema Dewanti Ema Dewanti ERVINA BHAKTI UTAMI Etin Diah Permanasari Fujianti, Fujianti GIGIH PANGESTU WITJI Hadi Sunaryo Hariyanti Hariyanti Hayati Hayati Hidayati, Ester Ilham Kuncahyo, Ilham Iqbal, Anwar Iqbal, Anwar Isra, Rafiq Al Kartika Tiara Wijayanti Khalishatunnada, Khalishatunnada Kisrini . Kristi, Aprina Kristi, Aprina Ladeska, Vera Mamik Ponco Rahayu Mardiyono Mardiyono, . Mauliza, Cut Nabila, Helvi Airin Nabila, Sausan Nila Marlita Nila Marlita, Nila Nora Wulandari Numlil Khaira Rusdi, Numlil Khaira Pegi Perdianti Perdianti, Pegi Puspitasari, Elva Fitriani R.Tjahyadi R.Tjahyadi R.Tjahyadi, R.Tjahyadi Rahmat, Amalia Riska Anggraini, Riska Sartika Novita Sari Siska Siska Siska Siska Susilo Susilo Syafitri, Yeshaira Zahra Shabira Titik Sunarni Titik Sunarni Vera Ladeska Viviandhari, Daniek Yudi Rinanto Yudi Rinanto