Article Per Year (5 Year)
p-Index From 2021 - 2026
3.218
P-Index
This Author published in this journals
All Journal Jurnal Ilmu Pertanian Indonesia ACTA VETERINARIA INDONESIANA Hemera Zoa Jurnal Sain Veteriner Jurnal Veteriner WARTAZOA Indonesian Bulletin of Animal and Veterinary Sciences Jurnal Medik Veteriner ARSHI Veterinary Letters JURNAL KAJIAN VETERINER Jurnal Kedokteran Hewan Jurnal Veteriner dan Biomedis Current Biomedicine Jurnal Veteriner
Sus Derthi Widhyari
Divisi Penyakit Dalam, Departemen Klinik, Reproduksi, Dan Patologi, Fakultas Kedokteran Hewan, Institut Pertanian Bogor Jl Agathis, Kampus IPB Dramaga, Bogor, Jawa Barat, Indonesia 16680
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Public Health Veterinary

Published : 43 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 43 Documents
Search

 1   2   3   4   5 
Clinical Signs and Haematology Profiles of Beagle Dogs with Tick Infestation Mihardi, Arief Purwo; Joesoef, Jayusman Arsiyanti; Wolo, Kathirina Beathrik Riwu; Esfandiari, Anita; Widhyari, Sus Derthi; Wulansari, Retno; Wijaya, Agus; Maylina, Leni
Jurnal Medik Veteriner Vol. 5 No. 2 (2022): October
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol5.iss2.2022.266-269

Abstract

Rhipicephalus sanguineus is one of the vectors that could induce diseases in dogs. A physical examination and haematology test could examine the dog's condition with tick infestation. Five dogs, beagle breeds from Veterinary Teaching Hospital, School of Veterinary Medicine and Biosciences, IPB University, have been examined for physical examination and CBC test. A haematology test was performed using a haematology analyzer and made the blood smear. Physical examination showed that 60% of dogs have a tick infestation, 80% have pallor, 60% have pruritus, 40% have crusted skin, and 100% have wounds in extremities. However, the body temperature and heart rate were relatively normal. Complete blood count test showed that red blood cells (RBC), peak cells volume, and haemoglobin (Hb) decreased (80%), MCHC increased (40%), thrombocytopenia (100%), leukopenia (40%), lymphocytopenia (60%), neutropenia (10%) and monositopenia (80%). The blood smear result showed all dogs have positive blood parasites, with the highest percentage being the third dog (0.056%). From the physical examination, CBC, and blood smear, it can be concluded that dogs with tick infestation would experience anaemia that showed by RBC, PCV, decreasing number of platelet and positive blood parasite.
Erythrogram Profile of Blood Samples Anticoagulated with Tri-potassium Ethylene Diamine Tetraacetic Acid (K3EDTA) Stored for 48 Hours at 4oC Azzahrah, Putri; Esfandiari, Anita; Mihardi, Arief Purwo; Widhyari, Sus Derthi; Wulansari, Retno; Ningtias, Putri Indah
Jurnal Medik Veteriner Vol. 7 No. 1 (2024): April
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jmv.vol7.iss1.2024.76-87

Abstract

Several pre-analytical variables influence hematological results, including anticoagulant use, storage temperature, and time between blood sample collection and analysis. Delayed sample analysis owing to prolonged storage could result in erythrogram profiles, which could complicate the interpretation of the resulting data. This study investigated the erythrogram profile of tripotassium ethylenediaminetetraacetic acid (K3EDTA) in blood samples stored for 48 h at 4°C. Ten healthy blood samples of Ongole crossbred cattle were collected into K3EDTA tubes from the jugular or coccygeal veins and analyzed for erythrogram profiles (erythrocyte counts, hemoglobin levels, hematocrit value, and erythrocyte morphology). Blood sample analysis for the control (0 h) was performed within ± 1.5 hours after collection, then the samples were refrigerated (4°C) and analyzed at 3, 6, 9, 12, 24, and 48 h. The results showed increased (p < 0.05) erythrocyte counts and hematocrit values after 9–24 and 6–48 h of storage, respectively. There was a significant difference in erythrocyte diameter between 0 h and other time observations (p < 0.05). Echinocytes were observed at 0 h of storage and continued to increase up to 48 h. Hypochromasia was also found at 6 to 48 hours of storage. Therefore, the analysis of blood samples for erythrogram parameters should be performed as soon as possible, preferably within three hours after collection, to ensure clinically reliable results.
Laporan Kasus: Suspek Hidronefrosis akibat Tumor Prostat pada Anjing di Rumah Sakit Hewan Pendidikan (RSHP) Sekolah Kedokteran Hewan dan Biomedis (SKHB) IPB University Wibowo, Deny Setyo; Wulansari, Retno; Esfandiari, Anita; Widhyari, Sus Derthi; Wijaya, Agus; Gunanti, Gunanti; Fitri, Arni Diana
Jurnal Sain Veteriner Vol 43, No 1 (2025): April
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.102272

Abstract

Seekor anjing jantan ras domestik berumur 16 tahun dibawa ke Rumah Sakit Hewan Pendidikan (RSHP), Sekolah Kedokteran Hewan dan Biomedis (SKHB), IPB University. Pasien datang dengan keluhan tidak mau makan hingga dua hari, berdiri dan jalan tidak stabil, muntah, nistagmus, dan sempat jatuh terguling. Pemeriksaan fisik palpasi abdomen menunjukkan adanya pembesaran serta nyeri pada kelenjar prostat. Setelah dilakukan pemeriksaan penunjang hematologi, anjing menunjukkan penurunan jumlah eritrosit, hemoglobin, hematokrit, trombosit, dan PCT. Hasil pemeriksaan kimia darah menunjukkan penurunan kadar SGOT serta peningkatan kadar BUN dan kreatinin. Hasil pemeriksaan USG menunjukkan adanya formasi kristal pada pyelum ginjal kiri, perubahan batas antara korteks dengan medula dan atrofi ginjal kanan, peningkatan ketebalan vesika urinaria, serta perubahan ekogenitas parenkim dan ukuran prostat. Hasil pemeriksaan radiografi menunjukkan adanya pembesaran pada prostat dan preputium. Hasil pemeriksaan urinalisis menunjukkan peningkatan UPC serta adanya protein, darah, kreatinin, dan leukosit. Kasus ini memiliki diagnosa banding yaitu hidronefrosis, tumor prostat, prostatitis, dan neuron injury dengan prognosis infausta. Penanganan pada kasus ini dilakukan dengan pemberian terapi berupa infus asering, suplemen, bronkodilatator, diuretik, serta antiemetik.  
Transmissible venereal tumor and anaplasmosis in a domestic dog Nuraliyu , Roro Iyaka; Laksamana , Vincentius Bryan; Novitasari , Dina; Widhyari , Sus Derthi
ARSHI Veterinary Letters Vol. 9 No. 1 (2025): ARSHI Veterinary Letters - February 2025
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.9.1.17-18

Abstract

Makalah ini melaporkan kasus tumor kelamin menular dan anaplasmosis pada anjing peliharaan. Seekor anjing betina domestik hitam-putih, berusia 2 tahun, berat 7,1 kg, dibawa ke klinik untuk diperiksa setelah diselamatkan. Pemeriksaan fisik menunjukkan infestasi Rhipicephalus sanguinis dan pembengkakan vagina dengan nodul berdiameter sekitar 5 mm. Hitung darah lengkap menunjukkan leukositosis, neutrofilia, dan eosinofilia. Hemoglobin, konsentrasi hemoglobin korpuskular rata-rata, dan nilai trombosit menurun. Hasil uji biokimia darah menunjukkan penurunan kadar protein total. Hasil sitologi nodul vagina konsisten dengan tumor kelamin menular. Anjing itu didiagnosis dengan tumor kelamin menular dan anaplasmosis. Perawatannya meliputi antibiotik doksisiklin, agen kemoterapi vinkristin, suplemen herbal fu fang, obat anti kutu dan caplak fluralaner, antihelmintik cazitel, suplemen Kalvidog, dan sampo obat untuk memperbaiki kondisi kulit.
Infeksi Babesia spesies bersamaan dengan virus corona enterik kucing dan giardiasis pada dua kucing betina Wulansari, Retno; Soesatyoratih, Roro; Widhyari, Sus Derthi; Suryono
ARSHI Veterinary Letters Vol. 9 No. 3 (2025): ARSHI Veterinary Letters - August 2025
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.9.3.63-64

Abstract

The premunition stage of babesiosis poses a significant risk of relapse due to immune suppression. This report describes two cats that presented to a veterinary clinic with lethargy, anorexia of several days’ duration, watery eyes, and loose stools. Both cats were unvaccinated and lived in an open environment shared with their owners. Initial clinical evaluation suggested feline coronavirus (FCoV) infection and giardiasis; however, subsequent peripheral blood smears revealed intracellular parasites consistent with Babesia sp.. The initial treatment targeted viral and protozoal infections using antiprotozoal and antiviral agents for seven days, followed by a 21-day regimen of clindamycin and multivitamins to manage babesiosis. Hematological analysis and Giemsa-stained peripheral blood smears revealed anemia, thrombocytopenia, and persistent babesiosis. Clindamycin therapy effectively reduced parasitemia and alleviated clinical signs, including anemia, anorexia, and weakness, although complete clearance of Babesia sp. from the peripheral blood was not achieved at the administered dosage.
Extra-hepatic biliary duct obstruction pada anjing ras Dachshund Kartjito, Nicolas Edward Christanto; Effendi, Siti Aisyah Rahmalia; Solinda, Gamelita Rizkawandi; Widodo, Setyo; Widhyari, Sus Derthi; Wulansari, Retno; Wijaya, Agus; Dewi, Fitriya Nur Annisa; Wibowo, Deny Setyo; Esfandiari, Anita
ARSHI Veterinary Letters Vol. 7 No. 2 (2023): ARSHI Veterinary Letters - Mei 2023
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.7.2.25-26

Abstract

Anjing jantan ras dachsund (Teckel) berwarna hitam, berusia 4 tahun dengan bobot badan 7,5 kg dibawa pemiliknya datang ke klinik hewan dengan keluhan muntah berulang. Hasil pemeriksaan hematologi menunjukkan polisitemia, leukositosis dan jumlah granulosit yang tinggi. Hasil uji biokimia darah menunjukkan peningkatan pada aktivitas SGPT/ALT, GAMA-GT, total bilirubin, total protein, albumin, rasio ALB/GLOB dan rasio BUN/CRE. Hasil radiografi menunjukkan adanya bentukan membulat radiolucent didekat organ hati. Diagnosa kasus klinis pada anjing ini yaitu extrahepatic biliary duct obstruction dan terapi simptomatik dilakukan dengan memberikan gastroprotektan, antiemetik, serta obat-obatan untuk membantu memperbaiki fungsi hati. Pengobatan dilakukan selama 2 minggu dan menunjukan perbaikan pada organ hati berdasarkan hasil pemeriksaan biokimia darah, diikuti dengan tidak ada dilatasi kantung empedu pada radiogram.
Symmetry dimethylarginine (SDMA) assay for diagnosis of kidney disease in dogs and cats: a mini review of case reports in Indonesia Dewi, Fitriya Nur Annisa; Widhyari, Sus Derthi; Mihardi, Arief Purwo; Widodo, Setyo; Esfandiari, Anita
ARSHI Veterinary Letters Vol. 8 No. 2 (2024): ARSHI Veterinary Letters - May 2024
Publisher : School of Veterinary Medicine and Biomedical Sciences, Bogor Agricultural University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29244/avl.8.2.35-36

Abstract

Symmetry Dimethylarginine (SDMA) is an important biomarker for early diagnosis of kidney disease. Studies suggest that SDMA is a more sensitive indicator of kidney function compared to traditional markers such as blood urea nitrogen (BUN) and creatinine. Since 2015, the International Renal Interest Society (IRIS) has established SDMA as one of the indicators for diagnosis and determining the stage of chronic kidney disease (CKD) in dogs and cats. SDMA assay use in veterinary clinics in Indonesia has empirically become more common. The aim of this study was to identify scientific reports on SDMA assay use in the diagnosis of kidney disease in dogs and cats in Indonesia. We performed a literature search in the Garuda portal and Google Scholar using the following keywords: “SDMA” or “Symmetry Dimethylarginine”, “dogs”, “cats” and “Indonesia”. The search strategy utilized English and Bahasa Indonesia, and the results were screened for relevance to the topic, and limited to studies conducted in Indonesia. Seven scientific articles in national and international journals reported the use of SDMA assay in cases of kidney disease in dogs or cats in Indonesia, published between 2021-2023. It is expected that SDMA assay use will continue to increase in veterinary practice settings in the country, and it is therefore critical to have a proper understanding of the advantages and limitations of SDMA use for kidney disease diagnosis.
THE EFFECTS OF AGE ON BIOCHEMISTRY PROFILES OF ACEH CATTLE BLOOD Khairita, Lia; Esfandiari, Anita; Widhyari, Sus Derthi; Winarsih, Wiwin
Jurnal Kedokteran Hewan Vol 15, No 3 (2021): September
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v15i3.21698

Abstract

The purpose of this study was to analyze the effects of age on the biochemistry profiles of aceh cattle, which included examinations of: total protein (TP), albumin, globulin, albumin/globulin ratio (A/G), aspartate aminotransferase (AST), gamma-glutamyltransferase (GGT), alkaline phosphatase (ALP), creatine kinase (CK), blood urea nitrogen (BUN), calcium (Ca), phosphorus (P) and magnesium (Mg) . Sixteen clinically healthy aceh cattle aged 2-4 years old, and 16 aceh cattle aged 4-6 years old were purposively selected for the study. Blood samples were drawn from the jugular vein and subjected to blood biochemistry measurements using commercial kits. The results showed that serum concentrations of TP, globulin, AST and Ca of aceh cattle were significantly (P0.05) higher in age group 4-6 years old, while ALP activity was significantly (P0.05) higher in age group 2-4 years old. In conclusion, age must be considered as a factor when interpreting the blood biochemistry profiles of aceh cattle.
ELECTROCARDIOGRAM OF PIGS (Sus scrofa) ANESTHETIZED WITH A COMBINATION OF KETAMINE-MEDETOMIDINE AND KETAMINE-ACEPROMAZINE Safitri, Jessica Anggun; Gunanti, Gunanti; Noviana, Deni; Widhyari, Sus Derthi
Jurnal Kedokteran Hewan Vol 14, No 4 (2020): December
Publisher : Universitas Syiah Kuala

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21157/j.ked.hewan.v14i4.16984

Abstract

This study aims to evaluate and compare the effects of the combination of ketamine-medetomidine and ketamine-acepromazine anesthesia on pig electrocardiogram (ECG) images. The study was conducted to see the ECG Leads II in six pigs which were divided into two groups. Group I (K1) was given a combination of ketamine (10 mg/kg BW) and medetomidine (0.08 mg/kg BW), while Group II (K2) was given a combination of ketamine (22 mg/kg BW) and acepromazine (1.1 mg/kg BW) intramuscularly. ECG recording was performed after the pigs were anesthetized at the surgical stage by attaching the recording electrodes to the front wall of the chest, front left and right ankles, and back right and left back ankles. The ECG recording used 1 voltage (1 cm = 1mV) with a speed of 25 mm/sec. The parameters observed were heart rate frequency, heart rhythm, P duration, P amplitude, PR interval, R amplitude, QRS interval, QT interval, ST segment, T wave, and Mean Electrical Axis (MEA). Data obtained from this study were analyzed by T-test. The results showed that K1 had an average heart rate of 100 x/minute, regular heart rhythm, P duration of 0.07 sec, P amplitude of 0.27 mV, PR interval of 0.17 sec, R amplitude of 0.75 mV, QRS interval of 0.05 sec, QT interval of 0.20 sec, ST segment of 0.17sec, T wave of 0.17 mV, and MEA of 83.60; meanwhile, K2 had an average heart rate of 122 x/minute, regular heart rhythm, P duration of 0.06 mm/sec, P amplitude of 0.23 mV, PR interval of 0.14 sec, R amplitude of 0.80 mV, QRS interval of 0.04 sec, QT interval of 0.16 sec, ST segment of 0.14 sec, T wave of 0.12 mV, and MEA of 68.60. The ketamine-medetomidine combination produced good quality of anesthetics for the cardiovascular system.
Pemberian Transfer Factor terhadap Gambaran Hematologi pada Kucing yang Terinfeksi Feline Panleukopenia Virus (FPV) Prastiwi, Nurul Anjar; Wulansari, Retno; Widhyari, Sus Derthi
Jurnal Sain Veteriner Vol 43, No 3 (2025): Desember
Publisher : Faculty of Veterinary Medicine, Universitas Gadjah Mada bekerjasama dengan PB PDHI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jsv.105326

Abstract

Feline Panleukopenia Virus (FPV) adalah penyakit viral yang sangat menular dengan tingkat morbiditas dan mortalitas tinggi, terutama pada anak kucing (kitten). Penyakit ini menunjukkan gejala berupa, muntah, diare, dehidrasi, dan depresi berat. Hingga saat ini, belum ditemukan terapi spesifik yang efektif, sehingga pengobatan bersifat suportif dan simptomatik. Salah satu pendekatan terapi yang mulai dikembangkan adalah penggunaan Transfer Factor sebagai imunomodulator. Penelitian ini bertujuan untuk mengevaluasi profil hematologi dan kimia darah pada kucing yang terinfeksi FPV sesudah diberi terapi kombinasi pengobatan konvensional dan suplementasi Transfer Factor. Sebanyak 24 ekor kucing, terdiri dari kitten dan kucing dewasa, dibagi menjadi empat kelompok berdasarkan umur dan jenis terapi yang diberikan. Pemeriksaan klinis, tes diagnostik FPV, serta analisis hematologi dilakukan setelah terapi untuk menilai efektivitas pengobatan. Hasil penelitian menunjukkan bahwa pemberian Transfer Factor secara signifikan mempengaruhi beberapa parameter hematologi, seperti peningkatan jumlah eritrosit, hemoglobin, hematokrit, serta trombosit. Parameter leukosit juga menunjukkan respons positif, terutama pada limfosit dan neutrofil. Hasil ini menunjukkan bahwa Transfer Factor dapat berperan sebagai terapi tambahan yang mendukung pemulihan kucing yang terinfeksi FPV dengan meningkatkan respons imun dan memperbaiki kondisi fisiologis pasien. Penggunaan Transfer Factor sebagai terapi suportif pada kasus FPV berpotensi meningkatkan tingkat kesembuhan serta mempercepat pemulihan klinis kucing yang terinfeksi. Studi lebih lanjut diperlukan untuk mengeksplorasi mekanisme kerja dan efektivitas Transfer Factor dalam terapi infeksi FPV.
Co-Authors . Herlina A.S. Satyaningtijas Aditia Dwi Cahyono Agus Wijaya Agus Wijaya Ali Hujarat Amani, Aqila Zata Anita Esfandiari April Hari Wardhana Aulia Andi Mustika Azzahrah, Putri Bayu Febram Bayu Firmala Kusuma Beata LYL Ayu Chusnul Choliq Deni Noviana Deny Setyo Wibowo Dewi, Fitriya Nur Annisa Dodi Darmakusuma Dondin Sajuthi Effendi, Siti Aisyah Rahmalia Erni Sulistiawati Esti Dhamayanti Fitri, Arni Diana Gunanti . Hammada Raudlowi I Ketut Sutama I Putu Kompiang I wayan Teguh Wibawan IETJE WIENTARSIH Intan Khoirunnisa Irda Khaeriyah Jessica Anggun Safitri Joesoef, Jayusman Arsiyanti Kartjito, Nicolas Edward Christanto Khairita, Lia Laksamana , Vincentius Bryan Leni Maylina Lia Khairita Lina Noviyanti Sutardi Muhammad Bintang Nabila Latifa Hafizsha Nadelia, Nurul Ningtias, Putri Indah Novitasari , Dina Nuraliyu , Roro Iyaka Pradianto, Bagus Ilham Prastiwi, Nurul Anjar Putri Indah Ningtias Putri Indah Ningtias Putri, Tiara Annisa Rahma, Kinanti Dwi Rahmawati Januar Retno Wulansari Riana Nurul Maulani Rizal Rahadian Ramdhany Rumlaklak, Yanse Yane Satriawan, Ivan Selma Laily Nur Afifah Setyo Widi Nugroho Setyo Widodo Setyo Widodo Shavrillia Inovanny Angesti Soesatyoratih, Roro Solinda, Gamelita Rizkawandi sri murtini . Supriyono Supriyono Suryono Susi Soviana Tika Aryanti Upik Kusumawati Hadi, Upik Kusumawati Wiwin Winarsih Wolo, Kathirina Beathrik Riwu Yanse Yanne Rumlaklak