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All Journal Majalah Kedokteran Bandung Dentika Dental Journal Dharmakarya : Jurnal Aplikasi Ipteks Untuk Masyarakat Dental Journal (Majalah Kedokteran Gigi) Jurnal Kedokteran Gigi Universitas Padjadjaran Padjadjaran Journal of Dentistry Padjadjaran Journal of Dental Researchers and Students Jurnal Material Kedokteran Gigi Jurnal Radiologi Dentomaksilofasial Indonesia (JRDI) Jurnal Health Sains

Inne Suherna Sasmita

Universitas Padjadjaran

Author-ID : 2541115

Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Energy Engineering Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Veterinary

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Ethanol extract of mangosteen (Garcinia Mangostana Linn) peel effect in inhibiting the growth of human tongue cancer cells Supri’s Clone 1, invitro Suanto, Edi; Oewen, Roosje Rosita; Sasmita, Inne Suherna; Supriatno, S.; Supratman, Unang
Padjadjaran Journal of Dentistry Vol 23, No 2 (2011): July 2011
Publisher : Universitas Padjadjaran

The incidence of tongue cancer in Indonesia reached 1.01% of all cancers and 42% of oral cavity cancer. Tongue cancer therapies including chemotherapy, radiotherapy, surgery, and all three combined therapy. Search for anti-cancer drugs currently switched on herbal plants, one of which is the mangosteen. Has the properties of mangosteen peel extract inhibited the growth of cancer cells. The purpose of the study, obtain IC50 of ethanol extract of mangosteen peel in inhibiting the growth of human tongue cancer cells SP-C1. Research carried out on 96 preparations of human tongue cancer SP-C1 were incubated with ethanol extract of mangosteen peel, preparations were classified in two groups of incubation time (24 hours and 48 hours) and each group will be given preferential treatment over 6 randomly different concentrations: 0 (control), 62.5 μg/mL, 125 μg/mL, 250 μg/mL, 500 μg/mL and 1000 μg/mL. Model experiments were 2 x 6 factorial experiment with eight replication for each cell. Test results with ANAVA, incubation (24 and 48 hour) SP-tongue cancer cells with various concentrations of C1 ethanol extract of mangosteen peel gives a highly significant, indicating differences cancer cell growth inhibition. Incubation time factor showed the long incubation effect on cancer cell growth inhibition. Furthermore, by Newman Keuls test, showed 500μg/mL concentrations of 24-hour incubation had the best effect. Conclusion of the study of ethanol extract of mangosteen peel could achieve with IC50 values of cell growth resistance 50.3% at a concentration of 500 μg/mL and an incubation time of 24 hours.

Prevalence of caries in intellectually impaired children at Sekolah Semangat Maju, Taiping, Perak, Malaysia Singh, Sanjit; Sasmita, Inne Suherna
Padjadjaran Journal of Dentistry Vol 21, No 2 (2009): July 2009
Publisher : Universitas Padjadjaran

Dental caries also known as tooth decay is a disease where a bacterial process damages the hard tooth structure. The aim of conducting this research was to obtain the prevalence of caries in the intellectually impaired children in Sekolah Semangat Maju, Taiping, Perak, Malaysia. The research was a descriptive research that utilized the survey technique. The population of the research was the students aged 7-17 years old from class 1 to class 5. The total sample for this research was 56 students. The students were examined for the presence of caries and the results were used to obtain the prevalence of caries in these subjects. The results from this study showed that the prevalence of caries based on the student’s medical diagnose was 68.42% for autism students, 57.14% for cerebral palsy students, 91.67% for Down’s syndrome students, 100.00% for mental retardation students and 42.86% for slow learner students. The conclusion from this research was that the overall prevalence of caries in intellectually impaired children at Sekolah Semangat Maju Taiping, Perak, Malaysia is 67.89%.

Role of Streptococcus Anginosus on the formation of dental caries Nonong, Yetty Herdiyati; Satari, Mieke Hemiawati; Sasmita, Inne Suherna
Padjadjaran Journal of Dentistry Vol 23, No 3 (2011): November 2011
Publisher : Universitas Padjadjaran

Generally, the etiology of dental caries is the cariogenic properties of bacteria, these are always associated with Streptococcus mutans. Glucosyltransferase fragment (Gtf) are also in other strains of Streptococcus such as Streptococcus anginosus, Streptococcus milleri which includes beta hemolysis. Genotypically B Streptococcus anginosus has genetic characteristics that are similar to Streptococcus mutans. The research objective was to determine the existence of Gtf B/C gene as a cause of caries in Streptococcus anginosus. The study was conducted in experimental laboratories with PCR technique by taking a sample of 20 children who had caries. The results showed there was the amplification of Streptococcus anginosus with a level of homology 96%, 97%, and 99%. The results of the Gtf genes amplification fragment B/C provided 600 pb ribbon. The conclusion was Streptococcus anginosus classified as cariogenic bacteria because they had Gtf B/C genes.

Craniofacial growth and development of Turner syndrome children Sasmita, Inne Suherna; Pertiwi, Arlette Suzy Puspa; Achmad, M Harun
Padjadjaran Journal of Dentistry Vol 21, No 2 (2009): July 2009
Publisher : Universitas Padjadjaran

Turner syndrome is a genetic disorder which characterized by specific physical appearance and the lost of one of sex chromosome in females. The most frequent chromosome constitution in Turner syndrome is 45X. This disorder may cause an interruption of growth and development in the whole body as well as in the craniofacial region. The oral manifestations of Turner syndrome are micrognathia, high palate, malocclusion, and the premature eruption of first permanent molars. This paper will discuss the oral manifestations associated with the craniofacial growth and development of Turner syndrome.

Co-Authors Anie Apriani Anissa Maya Kania Anissa Maya Kania Anne Agustina Suwargiani Arlette Suzy Puspa Pertiwi Asty Samiaty Setiawan, Asty Samiaty Bani Gidel Dela Armilda Dewi, Chita Sintya Dhia Thifal Malihah Dianegianty, Rine Dudi Aripin Edi Suanto, Edi elih, Elih Eriska Riyanti Fadhlil Ulum Abdul Rahman Fahmi Oscandar, Fahmi Fa``Iqoh Zulfal Majidah Georgiana Marsya, Georgiana Hasyimi, Ananto Ali Hidayat, Septian Rahmat Hilnia Zidnia Iwan Ahmad Musnamirwan Josevinda Ayu Pramesti Kholid, Ittaqi Tafuzi Kirana Lina Gunawan Kirana Lina Gunawan Lisda Damayanti Lusi Epsilawati M Harun Achmad, M Harun Meirina Gartika Mieke Hemiawati Satari Miryasandra, Astari Murnisari Dardjan, Murnisari Nadiya Mujaheda Alwafa Nani Murniati Nurwahidah, Sinta Putri, Tarisya Permata Ratna Ayu Alia Zulkarnain, Ratna Ayu Alia Ratna Indriyanti Risti Saptarini Primarti Roosje Rosita Oewen, Roosje Rosita S. Supriatno Sandy Dwiputra Sanjit Singh, Sanjit Setiawan, Asty S Setiawan, Editha Meydiana Sinta Nurwahidah Soekamto, Debrina Mayasari Sri Susilawati Sukmasari, Susi Supriatno Suwondo, Willyanti Syarief Hidayat Unang Supratman Wibowo, Kyle Raditya Williyanti Suwondo Willyanti Soewondo Willyanti Suwondo Yetty Herdiati Nonong Yetty Herdiyati Yetty Herdiyati Nonong, Yetty Herdiyati Yoana Yoana Yonathan, Heidy Stefanie Yurika Ambar Lita Yuti Malinda

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