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Laporan kasus: Karsinoma sel skuamosa paru dengan temuan sitologi dan histopatologi Lina, Juliana; Fadillah, Qori; Nadapdap, Marshall Jeremia; Mukti, Ade Indra; Novita, Cut Elvira
Buletin Kedokteran & Kesehatan Prima Vol. 3 No. 1 (2024): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v3i1.5564

Abstract

Kanker paru-paru sel skuamosa merupakan tantangan klinis yang signifikan dengan prognosis yang buruk. Laporan kasus ini menyajikan seorang pasien dengan gejala khas kanker paru-paru sel skuamosa. Hasil histopatologi mendukung temuan sitologi yakni tampak sebaran dan kelompokan sel epitel skuamous yang atipik dan pleomorfik, inti sel bentuk bulat dan oval, N/C ratio meningkat, kromatin kasar dengan anak inti menonjol, sitoplasma minimal dan eosinofilik. Untuk diagnosa yang lebih pasti dibutuhkan pemeriksaan imunohistokimia p40, p63, CK7, CK5/6 untuk prognosis dan terapi. Namun, sampel jaringan yang sangat sedikit dan tidak cukup untuk prosesing di laboratorium berikutnya, sehingga membutuhkan waktu yang lebih lama untuk tindakan berikutnya pada pasien. Kasus ini menyoroti pentingnya deteksi dini dan penatalaksanaan yang tepat untuk meningkatkan prognosis pasien. Laporan kasus ini memberikan wawasan berharga tentang karakteristik klinis dan tantangan dalam pengelolaan kanker paru-paru sel skuamosa.
Squamous cell carcinoma of the kidney: A case report Lina, Juliana; Karo, Reh Malem br; Theresia, Yohani; Fadillah, Qori
Buletin Kedokteran & Kesehatan Prima Vol. 4 No. 1 (2025): March
Publisher : Fakultas Kedokteran, Kedokteran Gigi, dan Ilmu Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34012/bkkp.v4i1.6544

Abstract

Primary renal squamous cell carcinoma (SCC) is a rare neoplasm strongly associated with a history of nephrolithiasis. Renal SCC is reported to have high morbidity and mortality rates, especially in the elderly population. Clinical manifestations of renal SCC are generally characterized by hematuria, flank pain, and a palpable mass in the retroperitoneal area. Histopathological examination reveals the infiltration of squamous cell nests that destroy the stroma. These cells show nuclear pleomorphism, an increased nuclear/cytoplasmic ratio, irregular nuclear membranes, coarse chromatin, prominent and dense basophilic nucleoli, and eosinophilic cytoplasm. These histopathological findings confirm the diagnosis of squamous cell carcinoma. The uniqueness of this case lies in the diagnosis of renal SCC in a relatively young age group, making it a distinct clinical concern. Further immunohistochemical examination, including CK5/6, p63, p40, and CK14 panels, is needed to determine the prognosis and appropriate treatment strategy. This case report emphasizes the importance of understanding kidney stone disease as a preventive measure against the development of renal SCC.
CORRELATION OF PROTEINURIA AND GLUCOSURIA LEVELS IN TYPE 2 DIABETES MELLITUS IN KAMPUNG KLUMPANG, NORTH SUMATRA Lee, Vanessa; Nasution, Sri Wahyuni; Fadillah, Qori
Jambura Journal of Health Sciences and Research Vol 6, No 4 (2024): OKTOBER: JAMBURA JOURNAL OF HEALTH SCIENCES AND RESEARCH
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35971/jjhsr.v6i4.27550

Abstract

Diabetes mellitus is the sixth cause of death worldwide, with 90% of cases being type II diabetes mellitus (T2DM), which is characterized by decreased insulin response and increased insulin resistance. T2DM patients have a higher risk of complications and worse health outcomes due to Glucosuria and proteinuria. This study investigated the relationship between proteinuria and diabetes mellitus, which is a relatively new topic in the medical literature. Although there have been previous studies regarding diabetes complications, the role of proteinuria as an early indicator in T2DM patients has not been widely explored. This study aims to improve the understanding and management of this condition by assessing the relationship between levels of proteinuria and Glucosuria in T2DM patients. This research was conducted in August 2024 at the Klumpang Village Office, Hamparan Perak. This cross-sectional study involved patients with blood glucose levels 126 mg/dL, HbA1c 6.5%, and who gave informed consent. Patients who meet the criteria are asked to provide a urine sample for measurement of proteinuria and Glucosuria using a dipstick test. Results showed that the average age of patients was ≤60 years, with a higher prevalence among women (ratio 55:44). Glucosuria and proteinuria were not detected in some patients (ratio 25:30). Among those with Glucosuria, 33.3% showed ++ levels. In contrast, the highest incidence of proteinuria was detected at trace levels (44.4%). The conclusion is that the Spearman's Rho correlation test revealed a moderate and statistically significant positive relationship between blood glucose levels, HbA1c, Glucosuria, and proteinuria (p0.05). In conclusion, blood glucose and HbA1c levels are positively associated with proteinuria and Glucosuria in T2DM patients.
The Relationship Between Single and Mixed Worm Infections and the Nutritional Status of Students at SDN 060824 Medan City Simaremare, Edwin Sani Erico; Nasution, Sri Wahyuni; Fadillah, Qori
COMSERVA : Jurnal Penelitian dan Pengabdian Masyarakat Vol. 4 No. 8 (2024): COMSERVA : Jurnal Penelitian dan Pengabdian Masyarakat
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/comserva.v4i8.2716

Abstract

Worm infections are a significant health issue among children, especially in areas with inadequate sanitation. This study aims to identify the results of fecal examinations for worm infections in children at SDN 060824, Medan City, and examine the relationship between single and mixed worm infections and their nutritional status. This research uses an observational analytic method with a cross-sectional approach. The sample consists of 50 students selected randomly, with data collected through fecal examination and nutritional status measurement. The results indicate that 4% of students tested positive for worm infections, while 96% were uninfected. Statistical analysis revealed no significant relationship between worm infections and students' nutritional status (p>0.05). This study concludes that worm infections among students in the study location do not directly impact their nutritional status. These findings provide a basis for the government and health agencies to focus on broader preventive programs for worm infections to support the overall health of children.
Uji Efektifitas Antibakteri Sabun Cair Dari Estrak Daun Jarum Tujuh Bilah (Pereskia Bleo) Terhadap Bakteri Staphylococcus Aureus Fakultas Kedokteran Universitas Prima Indonesia Hanifa Driantsani, Qonita; Fadillah, Qori; Wahyuni , Sri
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v9i10.50115

Abstract

Kebersihan kulit sangat penting untuk mencegah infeksi yang disebabkan oleh mikroorganisme, terutama bakteri seperti Staphylococcus aureus. Kulit berfungsi sebagai pelindung tubuh dan dapat menjadi pintu masuk bagi bakteri penyebab penyakit. Penggunaan sabun, khususnya sabun cair dan sabun antibakteri, semakin populer di masyarakat karena efektif dalam membersihkan kulit dan mencegah infeksi. Namun, ada kecenderungan untuk mencari alternatif bahan alami sebagai pengganti produk berbahan kimia sintetik. Salah satu tanaman yang memiliki potensi antibakteri adalah Daun Jarum Tujuh Bilah (Pereskia bleo). Penelitian ini bertujuan untuk mengeksplorasi manfaat ekstrak etanol dari daun tersebut melalui skrining fitokimia dan uji aktivitas antibakteri, sejalan dengan tren pengobatan tradisional yang semakin diminati sebagai solusi alami. Hasil penelitian diharapkan dapat memberikan wawasan mengenai potensi Daun Jarum Tujuh Bilah (Pereskia bleo) sebagai antibakteri alami untuk mendukung kesehatan kulit.
Uji Efektivitas Sediaan Sampo Ekstrak Daun Jarum Tujuh Bilah (Pereskia Bleo) Terhadap Pertumbuhan Jamur Candida Albicans Al-Faris, Muhammad Aji; Fadillah, Qori; Nasution, Sri Wahyuni; Sirait, Kristina
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v9i11.52293

Abstract

Ketombe adalah suatu kondisi yang tidak normal pada kulit kepala yang disebabkan oleh infeksi jamur Candida albicans. Daun Jarum Tujuh Bilah (Pereskia bleo) sebagai bahan alami, mengandung senyawa antijamur seperti flavonoid, fenol, tanin dan steroid. Tujuan dari penelitian ini adalah untuk mengembangkan formulasi sampo antijamur dengan menggunakan ekstrak etanol daun jarum tujuh bilah (Pereskia bleo). Penelitian diawali dengan membuat ekstrak daun jarum tujuh bilah yang diperoleh dengan metode maserasi. Kemudian ekstrak diformulasikan menjadi sediaan sampo dalam tiga variasi konsentrasi, yaitu 5%, 15%, dan 20%. Sediaan dievaluasi homogenitas dan viskositas serta pengaruh konsentrasi ekstrak etanol pada aktivitas antijamur. Hasil penelitian menunjukkan bahwa ekstrak daun jarm tujuh bilah(Pereskian bleo) dapat di formulasikan dalam sediaan sampo antiketombe yang homogen, berwarna hijau tua, dan memiliki viskositas >2000 cps. Aktivitas antijamur diuji menggunakan metode difusi cakram dengan mengamati daerah hambatan pertumbuhan jamur yang menunjukkan bahwa konsentrasi 5% dan kontrol (+) Ketoconazole memberikan diameter zona hambat tertinggi menunjukkan respons yang kuat dalam menghambat pertumbuhan mikroba.
The Relationship Between Parental Smartphone Use Duration and the Incidence of Stunting in Children in Medan City Wutama, Kevin; Pratama, Irza Haicha; Fadillah, Qori; Mastura, Indira Ade
Jurnal Indonesia Sosial Sains Vol. 6 No. 10 (2025): Jurnal Indonesia Sosial Sains
Publisher : CV. Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/jiss.v6i10.2025

Abstract

Stunting remains a major public health problem in Indonesia, with multidimensional impacts ranging from impaired physical growth to reduced human capital quality. Socioeconomic status, parental education, and parenting practices are recognized determinants, but the role of digital behavior, particularly smartphone use, remains underexplored. This study aims to analyze the association between parental smartphone use duration and stunting among children in Medan City. An analytical observational study with a case-control design was conducted involving 124 respondents (62 cases, 62 controls) selected through purposive sampling. Data were collected using sociodemographic questionnaires and the Smartphone Addiction Scale – Short Version (SAS-SV). Statistical analysis employed Chi-Square tests and Odds Ratio estimation. Most case respondents had a high school education (51.6%) and a family income of IDR 1,000,000–3,000,000 (64.5%), while control respondents were predominantly university graduates (88.7%) with incomes exceeding IDR 5,000,000 (54.8%). Smartphone addiction was more prevalent in the case group (71.0%) than in controls (21.0%). A significant association was found (p < 0.001), with OR = 9.214 (95% CI: 4.053–20.948). Excessive parental smartphone use is significantly associated with stunting in children, highlighting the need for preventive interventions that address digital behavior as an emerging risk factor.
Gambaran Preferensi Metode Pembelajaran (Edgar Dale`s Cone of Experience) Mahasiswa/I Prodi Sarjana Pendidikan Dokter UNPRI berdasarkan Tipe Kepribadian (16Personalities) Wijaya, Chrestellone Surya; Fadillah, Qori; Pratama, Irza Haicha
Jurnal Pendidikan Indonesia Vol. 6 No. 11 (2025): Jurnal Pendidikan Indonesia
Publisher : Publikasi Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59141/japendi.v6i11.8742

Abstract

Edgar Dale’s Cone of Experience, salah satu teori pembelajaran yang paling sering disalahartikan dalam dunia pendidikan. Jika bicara mengenai pendidikan, saat ini peran dari aspek non-kognitif seperti kepribadian menjadi semakin penting. MBTI (Myers-Briggs Type Indicator) merupakan salah satu instrumen yang paling dikenal dan digunakan secara luas di dunia. Dari hal ini, terciptalah penelitian yang memiliki tujuan untuk mencari gambaran preferensi serta rekomendasi metode pembelajaran berdasarkan tipe kepribadian. Penelitian ini menggunakan pendekatan kuantitatif, variabel diambil melalui database dan kuesioner yang dibuat sendiri melalui google form serta dari 16Personalities yaitu NERIS Type Explorer®, lalu data dianalisis secara statistik deskriptif. Dari 280 sampel, ENFJ-A / ENFJ-T menjadi tipe kepribadian yang paling dominan. Verbal Symbols menjadi metode pembelajaran yang paling banyak dipilih serta menjadi rekomendasi metode pembelajaran dalam lingkup pembelajaran kuliah pakar. Di lain sisi dalam lingkup pembelajaran praktikum, Demonstrations menjadi metode pembelajaran yang paling banyak dipilih, sedangkan untuk rekomendasinya ada empat metode pembelajaran yaitu Recordings, Radio & Still Pictures, Motion Pictures & Educational Television, Demonstrations serta Direct Purposeful Experiences. Namun perlu digarisbawahi bahwasannya temuan yang tertulis dalam narasi di atas hanyalah sebagian informasi yang diringkas berdasarkan data yang paling mencolok, sedangkan untuk mengetahui detail terkait preferensi serta rekomendasi metode pembelajaran dari ke-16 tipe kepribadian, kita dapat melihatnya di bagian hasil dan pembahasan.
Hubungan Kadar Gula Darah Terhadap Gambaran Funduskopi Pasien Retinopati Diabetik Operable Dan Non Operable Di Rumah Sakit Prima Vision Tahun 2023-2025 Rahmah, Ratu Aulia; Fadillah, Qori; Pratama, Irza Haicha
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v10i11.62423

Abstract

This study aims to determine the effect of Channa striata extract on Malondialdehyde (MDA) levels and the histopathological features of the heart in liver cirrhosis model rats. This experimental research used a randomized post-test only control group design with male Wistar rats (Rattus norvegicus) as test subjects. Liver cirrhosis was induced using carbon tetrachloride (CCl₄) for six weeks. The rats were divided into control and treatment groups, each receiving different doses of Channa striata extract. The observed parameters included cardiac MDA levels as an indicator of oxidative stress and histopathological changes in heart tissue examined using hematoxylin-eosin (HE) staining. The results showed that Channa striata extract significantly reduced MDA levels compared to the control group and improved the histological structure of the heart in cirrhosis model rats. These findings indicate that Channa striata possesses hepatocardioprotective potential through antioxidant mechanisms that can reduce tissue damage caused by oxidative stress.
Maternal Age at Marriage and Risk of Childhood Stunting: Evidence from a Case-Control Study in North Sumatra, Indonesia Sidabutar, Anjas Domini; Pratama, Irza Haicha; Fadillah, Qori; Angwyn, Wilbert; Rimadeni, Yeni; Anggriani, Theresia
Gema Lingkungan Kesehatan Vol. 23 No. 4 (2025): Gema Lingkungan Kesehatan (on progress)
Publisher : Poltekkes Kemenkes Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36568/gelinkes.v23i4.403

Abstract

Stunting remains a major public health issue in Indonesia, particularly in urban areas such as Medan. While socioeconomic and nutritional factors are well recognized, the influence of maternal age at marriage on child growth is less explored. This study examined the association between maternal age at marriage and childhood stunting in Medan, Indonesia. Methods. An analytical observational study with a case–control design was conducted from January to March 2025 across several community health centres in Medan. A total of 124 mother–child pairs (62 stunted and 62 non-stunted children) were selected using cluster random sampling. Data were collected through structured interviews and health-record reviews. Stunting was defined as height-for-age Z-score < -2 SD based on WHO standards. Logistic regression was used to assess the relationship between maternal age at marriage (<25 years vs ≥25 years) and stunting, adjusting for maternal education, maternal health during pregnancy, socioeconomic status, and birth weight. Children of mothers who married before age 25 had significantly higher odds of being stunted compared with those whose mothers married later (adjusted OR = 2.85; 95% CI: 1.71-4.76; p < 0.001). Low maternal education (adjusted OR = 2.12; p = 0.021) and low birth weight (adjusted OR = 2.43; p = 0.030) were also independent predictors of stunting. Conclusion. Maternal marriage before 25 years is a strong determinant of childhood stunting in urban Medan. Delaying maternal marriage, enhancing women’s education, and strengthening maternal health programs could substantially reduce stunting prevalence. This study contributes new evidence to Indonesia’s national efforts to prevent stunting through life-course and policy-oriented interventions.