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All Journal E-Jurnal Medika Udayana Jurnal Farmasi Klinik Indonesia Journal of Economic, Bussines and Accounting (COSTING) YUME : Journal of Management Jurnal Biomedika dan Kesehatan Jurnal Manajemen dan Administrasi Rumah Sakit Indonesia (MARSI) Medika Kartika : Jurnal Kedokteran dan Kesehatan Community Engagement and Emergence Journal (CEEJ) Jurnal Ners AKSELERASI: Jurnal Ilmiah Nasional Journal of Humanities, Social Science, Public Administration and Management (HUSOCPUMENT) Jurnal MedScientiae Jurnal Kedokteran Meditek Maneggio Indonesian Journal of Biomedicine and Clinical Sciences Jurnal Bioteknologi & Biosains Indonesia (JBBI) J-CEKI Jurnal Ekonomi, Manajemen, Akuntansi Jurnal Bioteknologi & Biosains Indonesia
Wani Devita Gunardi
Universitas Kristen Krida Wacana
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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The Effect Of Knowledge And Experience Of Community Care On Interest In Treatment Moderated By Socioeconomics : (Study on Patients of Kefamenanu Hospital, TTU Regency) Astrid, Mariana; Gunardi, Wani Devita; Wahyoedi, Soegeng
Journal of Humanities, Social Science, Public Administration and Management (HUSOCPUMENT) Vol. 5 No. 2 (2025): April: Journal of Humanities, Social Science, Public Administration and Managem
Publisher : ID Solutions

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51715/husocpument.v5i2.322

Abstract

RSUD Kefamenanu is one of the hospitals owned by the Regional Government of North Central Timor Regency which borders directly with the State of Timor Leste. RSUD Kefamenanu is the main referral for health services in North Central Timor Regency. The objectives of this study were (1) to analyze the effect of knowledge on interest in treatment at Kefamenanu Regional Hospital, North Central Timor Regency (2) to analyze the effect of previous treatment experience on interest in treatment at Kefamenanu Regional Hospital, North Central Timor Regency (3) to analyze whether socioeconomics moderates the effect of knowledge on interest in treatment at Kefamenanu Regional Hospital, North Central Timor Regency (4) to analyze whether socioeconomics moderates previous treatment experience on interest in treatment at Kefamenanu Regional Hospital, North Central Timor Regency. This research was conducted with a quantitative approach using a cross-sectional study design. This research was conducted at Kefamenanu Hospital, North Central Timor Regency. The population in this study were all patients of Kefamenanu Hospital, North Central Timor Regency with a sample size of 100 people. The analysis method used is moderation regression analysis. The results of the analysis show that (1) There is a positive relationship between service knowledge and interest in seeking treatment at Kefamenanu Hospital, This means that the better the patient's service knowledge, the higher the level of interest in seeking treatment at Kefamenanu Regional Hospital (2) There is a positive direct relationship between interest in seeking treatment at Kefamenanu Regional Hospital, meaning that the higher the patient's perception of previous treatment experience, the higher the level of interest in seeking treatment at Kefamenanu Regional Hospital (3) Socioeconomics partially moderates the effect of knowledge on interest in seeking treatment at Kefamenanu Regional Hospital, North Central Timor Regency (4) Socioeconomics partially moderates previous treatment experience on interest in seeking treatment at Kefamenanu Regional Hospital, North Central Timor Regency.
Pengaruh Kualitas Layanan dan Citra Merek Terhadap Loyalitas Pasien Rawat Jalan Dimediasi oleh Kepuasan Pasien (Studi Kasus di RS Bunda Sejati) Dewi, Vica Christia; Gunardi, Wani Devita
Community Engagement and Emergence Journal (CEEJ) Vol. 6 No. 4 (2025): Community Engagement & Emergence Journal (CEEJ)
Publisher : Yayasan Riset dan Pengembangan Intelektual

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37385/ceej.v6i4.8845

Abstract

Persaingan rumah sakit di era modern tidak hanya ditentukan oleh teknologi medis, tetapi juga oleh kualitas layanan dan citra merek yang ditawarkan kepada pasien. RS Bunda Sejati menghadapi tantangan rendahnya jumlah kunjungan pasien rawat jalan yang belum mencapai target. Berdasarkan hasil observasi dan ulasan pasien menunjukkan adanya keluhan terkait pelayanan, seperti sistem antrean, keterlambatan dokter, dan kenyamanan fasilitas. Masalah ini mendorong perlunya evaluasi atas faktor-faktor yang memengaruhi loyalitas pasien. Penelitian ini bertujuan untuk menganalisis pengaruh kualitas layanan dan citra merek terhadap loyalitas pasien rawat jalan di RS Bunda Sejati, dengan kepuasan pasien sebagai variabel mediasi. Pendekatan kuantitatif digunakan dalam penelitian ini dengan metode Partial Least Square-Structural Equation Modeling (PLS-SEM) menggunakan aplikasi SmartPLS versi 4 dengan melibatkan 100 responden pengguna layanan rawat jalan Non-BPJS Kesehatan. Hasil penelitian menunjukkan bahwa kualitas layanan dan citra merek berpengaruh positif dan signifikan terhadap kepuasan pasien. Kualitas layanan juga memiliki pengaruh langsung yang signifikan terhadap loyalitas pasien, sementara citra merek hanya berpengaruh tidak langsung melalui kepuasan pasien. Kepuasan pasien terbukti menjadi mediator yang signifikan dalam hubungan antara kualitas layanan dan citra merek terhadap loyalitas pasien. Penelitian ini menegaskan pentingnya rumah sakit untuk terus meningkatkan kualitas layanan berdasarkan dimensi SERVQUAL serta memperkuat citra merek guna membangun loyalitas jangka panjang. Implikasi praktis dari hasil ini menjadi pedoman strategis bagi RS Bunda Sejati dalam upaya meningkatkan kinerja layanan dan daya saing.
Efektivitas Efektivitas Toilet Seat Sanitizer terhadap Bakteri Escherichia coli Penghasil Extended-Spectrum Beta-Lactamase: Escherichia coli Penghasil Extended-Spectrum Beta-Lactamase Pasaribu, Donna Mesina; Gunardi, Wani Devita; Andini , Natasya Johanna
Jurnal MedScientiae Vol. 4 No. 2 (2025): Agustus
Publisher : Universitas Kristen Krida Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36452/jmedscientiae.v4i2.3745

Abstract

The toilet is one of the facilities provided to meet the needs of users with various backgrounds of different hygiene behavior, so that they can be a source of bacterial transmission, one of which is Escherichia coli (E.coli), which is resistant to producing Extended-Spectrum Beta-Lactamase (ESBL). E.coli producing ESBL can cause infection of various diseases, to overcome this, preventive measures are taken to reduce the level of risk transmission through the use of toilet seat sanitizers. This study aims to determine the effectiveness of toilet seat sanitizer against E.coli producing ESBL. This research is a descriptive observational laboratory study using a toilet seat sanitizer with an active substance of 50%-Benzalkonium Chloride and Ethyl Alcohol 96% against E.coli producing ESBL American Type Culture Collection (ATCC) 35218. The phenol coefficient test was used to measure the effectiveness of the toilet seat sanitizer was compared with phenol, Minimum Inhibitory Concentration (MIC) and Minimal Bactericidal Concentration (MBC) were tested using the tube method. This study showed that the coefficient of toilet seat sanitizer effective against E.coli producing ESBL was 4,5. MIC active substance toilet seat sanitizer is effective at a concentration of 0,3125%, and MBC at a concentration of 0,625%. The author concludes that the results of the MIC and MBC prove that a toilet seat sanitizer active substances 50%-Benzalkonium Chloride and Ethyl Alcohol 96% is effective as a disinfectant against E.coli producing ESBL ATCC 35218.
Pengaruh Penggunaan Rekam Medis Elektronik (Rme) Dan Stres Kerja Terhadap Turnover Intention (TI) Tenaga Perawat Dengan Kepuasan Kerja Sebagai Variabel Mediasi Simon, Flyndie; Widjaja, Bernard Tirto; Gunardi, Wani Devita
Jurnal Manajemen dan Administrasi Rumah Sakit Indonesia (MARSI) Vol 9, No 4 (2025): Jurnal Manajemen dan Administrasi Rumah Sakit Indonesia (MARSI)
Publisher : LPPM Universitas Respati Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52643/marsi.v9i4.6739

Abstract

Turnover intention is an enemy within an organization and difficult to be detected early. In 2019, the turnover rate for nurses reached its highest value compared to the previous four years. The era of digital transformation has the potential to provide opportunities for improving work processes, including in the healthcare world such as the form of electronic medical record systems. This study is a quantitative, cross-sectional study using a questionnaire distributed to 80 emergency department nurses in West Jakarta. Data was analyzed using SEM partial least squares (PLS) method. The results showed that the use of electronic medical records (EMR) and work stress had a significant effect on job satisfaction, work stress and job satisfaction had a significant effect on turnover intention, and the effect of work stress on turnover intention can also be mediated by job satisfaction. On the other hand, the use of EMR did not have a significant effect on turnover intention and the effect of EMR usage on turnover intention could not be mediated by job satisfaction. From this study, the effectiveness of implementing the EMR system in healthcare services can be examined in relation to work stress, job satisfaction, and turnover intention of working healthcare professionals, especially nurses in the emergency department.
Prevalensi dan Pola Kepekaan Acinetobacter baumannii di Ruang Rawat Intensif RS Swasta di Jakarta Dharmawan, Ade; Devita, Arleen; Gunardi, Wani Devita; Layanto, Nicolas
Jurnal Biomedika dan Kesehatan Vol 6 No 2 (2023)
Publisher : Fakultas Kedokteran Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/JBiomedKes.2023.v6.178-185

Abstract

Background Acinetobacter baumannii is one of the bacteria that cause nosocomial infections, especially in the intensive care unit. These bacteria can cause infections, including bacteremia, pneumonia, urinary tract infections, surgical site infections, and meningitis. Most of these bacteria are multi-resistant to various antibiotics, impacting cure rates and length of stay. This study aimed to determine these bacteria's prevalence and antibiotic susceptibility patterns in the intensive care unit. Methods This research is descriptive research with a retrospective approach. The data was taken from the antibiotic susceptibility report in the intensive care unit of a private hospital in Jakarta in the period January 2020 – December 2021. The antibiotic susceptibility report was processed using the WHONET 2018 software. Results From 681 specimens examined in the intensive care unit, the prevalence of Acinetobacter baumannii was 28.7%, 80% of which came from respiratory specimens. In the sensitivity test results, only the antibiotic Colistin has the best sensitivity to this bacteria, which is 100% sensitive, while other antibiotics have poor sensitivity. Conclusions Acinetobacter baumannii is the bacteria that causes infection in the intensive care unit, with almost all of them being multi-drug resistant bacteria.
TELAAH PUSTAKA: PERAN AG-PTFE (PELAPIS KATETER URINE) UNTUK MENCEGAH CATHETER ASSOCIATED URINARY TRACT INFECTION (CAUTI) Haq, Satria Addienul; Gunardi, Wani Devita; Pasaribu, Donna Mesina Rosadini; Sumbayak, Erma Mexcorry
Medika Kartika : Jurnal Kedokteran dan Kesehatan Vol 6 No 4 (2023): Medika Kartika : Jurnal Kedokteran dan Kesehatan
Publisher : Fakultas Kedokteran Universitas Jenderal Achmad Yani

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Biofilm pada kateter merupakan salah satu penyebab terjadinya Catheter Associated Urinary Tract Infection (CAUTI). Telaah pustaka ini bertujuan mengetahui manfaat dan efektivitas pelapisan antibiofilm pada kateter urine dalam mencegah CAUTI. Pustaka yang dihimpun dalam telaah ini diperoleh melalui database electronic seperti Proquest dan PubMed menggunakan beberapa kata kunci yaitu, antibiofilm, biofilm, catheter, dan CAUTI. Semua jurnal yang diperoleh diseleksi menggunakan kriteria yang telah ditentukan, seperti artikel penelitian eksperimental, tahun publikasi kurang dari 10 tahun, dan penelitian menggunakan lapisan antibakteri pada permukaan kateter. Delapan jurnal hasil seleksi digunakan sebagai acuan utama pada telaah pustaka ini. Efektivitas yang baik dalam mencegah terbentuknya biofilm ditunjukkan oleh beberapa antibiofilm berikut, yakni, Amino Selulosa-nanosphere (ACNS), Chlorhexidine-nanosphere (CHX-NS), Ag/Poli-p-xylylenen hydrophilic (Ag/PPX-N), Perak-polytetrafluoroethylene (AG- PTFE), Perak-nanopartikel (Ag-NPs), Sodium selenite, dan Octenidine Dihydrochloride (OH). Bakteriuria dapat dihambat dalam waktu lama (> 30 hari) oleh antibiofilm Perak-polytetrafluoroethylene (AG- PTFE). Hal tersebut menunjukkan bahwa pelapisan kateter menggunakan antibiofilm memiliki potensi dalam mencegah terjadinya bakteriuria dan terbentuknya biofilm penyebab CAUTI. Kata Kunci: antibiofilm, CAUTI, kateter DOI : 10.35990/mk.v6n4.p395-405
BIOTECHNOLOGY OF PRODIGIOSIN: RECENT DEVELOPMENTS AND TECHNOLOGICAL CHALLENGES Gunardi, Wani Devita; Margaretha; Timotius, Kris Herawan
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 10 No. 2 (2023)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2023.2010

Abstract

Background: Prodigiosin is produced by Serratia marcescens. It has several pharmacological benefits, such as anticancer, antimicrobial, and antidaibetic. However, prodigiosin production still faces problems because it cannot be produced effectively, efficiently, and cheaply. Objective: This study aimed to conduct a review that can explain the upstream and the downstream process in prodigiosin production. Methods: Articles were searched from PubMed and ScienceDirect with the keywords prodigiosin and Serratia marcescens from Juny until September 2023 including review and original article. Relevant data and information were then extracted. Results: Prodigiosin has spectrometrical characteristics, which are crucial for evaluating its production, extraction, and purification identification. Submerged or solid-state fermentation is applicable for prodigiosin production, but solid-state fermentation is better. The kind of growing substrates and the cultural condition influence it. The use of oil-based carbon sources is recommended for the high productivity of prodigiosin. In order to have a cheap, effective, and efficient production process, different experiments have been conducted. Standard extraction and purification methods can carry out the downstream process. Conclusion: Prodigiosin can be produced via submerged or solid-state fermentation. Using cheap and readily available substrate are the key to success for the upstream and downstream process. The standard extraction and purification methods are available.This findings can be used as a basis for further research regarding large-scale production of prodigiosin with the cheap, effective, and efficient methode.
MICROBIAL CONTAMINATION AND BIOACTIVE COMPOUNDS OF JAMU BERAS KENCUR Gunardi, Wani Devita; Teiseran, Virginia Marsella; Timotius, Kris Herawan
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 11 No. 2 (2024)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2024.5966

Abstract

Background: Jamu Beras Kencur (JBK) is recognized as an herbal medicine, containing two main components: the rhizome of Kaempferia galanga and rice. While previous research has identified bioactive compounds in galangal rhizomes, such as Ethyl p-Methoxycinnamate (EPMC), Ethyl-cinnamate, and Kaempferol, there are few reports on polar or aqueous compounds in JBK. LC-MS/MS and GC-MS enable comprehensive analysis of bioactive compounds, with LC-MS/MS detecting non-volatile, polar, and thermally sensitive compounds like flavonoids and glycosides, while GC-MS analyzes volatile and semi-volatile compounds, such as terpenoids, providing precise separation and identification. Therefore, this study were to know the amount and the growth of contaminant bacteria, yeast and mold; to determine the main bioactive compounds in JBK; and to determine the bioactive compound in aqueous and ethanolic extracts of rhizome that analysed with LC-MS/MS and GC-MS. Methode: JBK samples were sourced from local producers in West Jakarta, freshly prepared, and immediately analyzed for microbial contamination and bioactive compounds. Result: The analysis revealed microbial contamination in JBK, including Escherichia coli, Staphylococcus aureus, Coliform, yeast, and mold. Additionally, three novel flavonoid glycosides were identified: Chrysoeriol-4'-O-β-D-glucopyranoside, Patuletin-7-O-[6′′-(2-methylbutyryl)]-glucoside, and Acacetin-7-galactoside. Conclusion: Therefore, from the pharmacological perspective, JBK has the potentials as a healthy herbal drink. However, further preclinical and clinical studies are essential to validate its safety and efficacy for clinical use, which could pave the way for its integration into mainstream healthcare as a natural therapeutic option.
Co-Authors Ade Dharmawan Andini , Natasya Johanna Astrid, Mariana Berlianti Bulovannelisa Meykward Salamahu Bernard T. Widjaja Devita, Arleen Dewi, Vica Christia Diana Wijaya Donna Mesina Rosadini Pasaribu Donna Mesina Rosadini Pasaribu Eka Desy Purnama Eka Desy Purnama Eka Desy Purnama Elisabeth D. Harahap Erma Mexcorry Sumbayak Ernawaty Tamba Eva Oktavia Eva Oktavia, Eva Evan Luke Aditya Evrilia Trihandayani Fushen Fushen Fushen Fushen, Fushen Gratia Erlinda Tomasoa Handy Winata Hansel Sanchia Haq, Satria Addienul Haryono, Budi Hikmah, Dian Nurul Ivan Yoseph Saputra Jannah, Ega Farhatu Kintan Utami Kris Herawan Timotius Layanto, Nicolas Lepianda, Jessica Mahardik, Ngakan Made Ari Marcel Antoni Margaretha MH, Fushen Mohamad Yanuar Prasetyo Nugroho Monica Puspa Sari Muhammad Faturrahman Adani Muhammad Nazmi Nazmi, Muhammad Ngakan Made Ari Mahardik P.M Budi Haryono Pasaribu, Donna Mesina Restu Aritonang Rina, Veronica Samantha Saparso Saputra, Ivan Yoseph Sari, Monica Puspa Simon, Flyndie Soegeng Wahyoedi Sudradjat, Susana Elya Tania, Rada Teiseran, Virginia Marsella Tintin Supriatin Utami, Kintan Widjaja, Bernard Tirto Widya Widya, Widya