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Journal : Medula

Hubungan Kadar Timbal dalam Darah terhadap Kejadian Hipertensi pada Operator SPBU di Kota Kendari Noviarsih Muslimah; Hartati Hartati; Fedelia Raya
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 2 (2017)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (188.946 KB) | DOI: 10.46496/medula.v4i2.2815

Abstract

ABSTRACTHypertension is a common health problem and often asymptomatic until advanced stages of development and often leads to death. One of the factors that play a role in the occurrence of hypertension is a heavy metal, that is lead (Pb) which is used as an additional chemical mixture of gasoline. Gas station’s operator is one of the jobs are high-risk exposure to lead for a long time. This study aims to determine the association of blood lead levels with incidence of hypertension among the gas station’s operators in Kendari. This study used cross sectional design with observational analytic approach. The study was conducted at nine stations in Kendari and Forensic and Molecular Biology Laboratory, Faculty of Mathematics and Science, Haluoleo University, Kendari on 16 - 20 December 2016. Sample consisted of 30 operators of gas station, using proportional stratified sampling technique. The instrument used in this study were questionnaires and testing blood specimens in the laboratory by ashing method. Analysis of the data used in this study was Fisher Exact Test. The result showed respondents with normal blood lead levels are 6 respondents (20.0%) and abnormal blood lead levels are 24 respondents (80.0%). Respondents who have hypertension are 26 respondents (86.7%) and respondents who did not have hypertension are 4 respondents (13.3%). Respondents with normal lead levels who had hypertension totaled 2 respondents (6.7%) and who do not have hypertension totaled 4 respondents (13.3%). Respondents with abnormal lead levels who had hypertension totaled 24 respondents (100.0%) and who do not have hypertension numbered 0 respondents (0.0%). Based on the result of data analysis using the Fisher Exact statistical tests on the correlation of blood lead levels in the incidence of hypertension among the gas station’s operators  in Kendari, p value = 0.001 which means that H0 is rejected. There is correlation between blood lead level with incidence of  hypertension among the gas station’s operators in Kendari .Keywords: Lead in the blood, hypertension, gas station’s operator
Antibacterial Activity Test on Ethanol Extract of Gedi Leaf (Abelmoschus manihot L.) on the Growth of Escherichia coli and Staphylococcus aureus Lista Yul Zamrul; Hartati Hartati; Parawansah Parawansah
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 6, No 3 (2019): Edisi Suplemen
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (74.058 KB) | DOI: 10.46496/medula.v6i3.9650

Abstract

ABSTRACTBackground: Infectious diseases are one of the major causes of death worldwide, mostly caused by bacteria. The use of less targeted antibiotics leads to resistance cases, thus encouraging the discovery of  alternative  medicine.In  general,  gedy  leaves  are  known  as  animal  feed  but gedy  leaves  contain antibacterials such as flavonoids, saponins, tannins and terpenoids. Research Purpose:This study aims to determine the antibacterial activity of ethanol extract of gedy leaves on the growth of E. coli and S. aureus. Research Method: This research uses post test only control design, free variable is ethanol extract of gedi leaves and dependent variable is bacterial growth inhibition zone. Ginger leaf ethanol extract was obtained by maceration method for 3 x 24 hours. The test of antibacterial activity using the well diffusion method. Research result: The results of ethanol extract of gedi leaf with concentration of 2.5 mg/ml, 1.25 mg/ml and 0.625 mg/ml resulted in inhibition zone to E. coli growth successively; they were 11.33 mm, 8 mm and 6.3 mm. Extracts of the same concentration also showed inhibition of S. aureus growth with inhibit zone of 8 mm, 3.6 mm and 2 mm. Conclution:The conclusion of this research is the extract ethanol of gedi leaf has antibacterial activity against E. coli and S. aureus.Keywords: Antibacterial,E. coli and S. aureus , Gedi leaf (Abelmoschus manihot L.), Infection.
Uji Aktivitas Ekstrak Etanol Daun Dadap Serep (Erythrina lithosperma Miq) sebagai Antibakteri terhadap Bakteri Salmonella typhi Andi Noor Kholidha; I Putu Wira Putra Suherman; Hartati Hartati
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 4, No 1 (2016)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (258.842 KB) | DOI: 10.46496/medula.v4i1.2555

Abstract

Dadap serep (Erythrina lithosperma Miq) is one of the plants that grow in Indonesia. Dadap serep leaves are commonly used as a traditional medicin. It can be used as an antimicrobial. This study aims to determine the inhibition of Dadap Serep (Erythrina lithosperma Miq) Leaf Extract  on the growth of the bacteria Salmonella typhi. The methods used in this research was an analytic experimental test. The samples of this study are Leaf Extract of Dadap Serep (Erythrina lithosperma Miq), which is divided into eight concentration, i.e. the concentration of 200,000 ppm, 100,000 ppm, 50,000 ppm, 25,000 ppm, 12,500 ppm, 6,250 ppm, 3,125 ppm, 1,560 ppm and two control i.e. a positive controls and a negative controls. Each test was repeated three times. Antibacterial activity test performed by disc diffusion method, wherein the diameter of each extract was determined and assessed their effectiveness inhibitory zone with chloramphenicol. Minimum Inhibitory Concentration (MIC) was determined by disc diffusion method togeth er with the inhibition test. We then measured at the lowest concentration of extract that they can inhibit the bacteria Salmonella typhiTop of FormBottom of Form. The results showed that the leaves of Dadap Serep (Erythrina lithosperma Miq) has antibacterial activity against growth of bacteria Salmonella typhi. MIC seen from the leaves of Dadap Serep is 50,000 ppm with inhibition zone diameter of 1.3 mm were formed. Diameter of clear zone is highest at a concentration of 200,000 ppm with inhibition zone diameter formed is 4.83 mm. Phytochemical test results on Leaf of Dadap Serep (Erythrina lithosperma Miq) retrieved alkaloids, flavonoids, tannins and saponins are positive.From this research it can be concluded that the extracts from dadap serep leaves (Erythrina lithosperma Miq) has antibacterial activity against growth of bacteria Salmonella typhi.Keywords: Dadap serep leaves (Erythrina lithosperma Miq), Salmonella typhi, Minimum inhibitory concentration (MIC), Antibacterial test
Uji Aktivitas Ekstrak Etanol Daun Tembelekan (L.camara L.) terhadap Pertumbuhan Bakteri Salmonella typhi Ulilta Muktadira; Satrio Wicaksono; Hartati Hartati
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 5, No 2 (2018)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (170.373 KB) | DOI: 10.46496/medula.v5i2.4369

Abstract

Background: Infectious diseases are the prime reason of high morbidity and mortality rate especially in developing countries like Indonesia which is mostly caused by bacteria. One of the plants which can be used as an antibacterial alternative ingredient is tembelekan leaf. Research Purpose: This study aimed to determine the activity of ethanol extract of tembelekan leaf on the growth of S.typhi. Research Method: The research uses  post test only control design.Independent  variable is the ethanol extract of tembelekan leaf and dependent variable is the inhibition zone of the growth of bacteria. Antibacterial activity was tasted using pitting diffusion method.Chloramphenicolusedas a positive controland aquadest as a negativecontrol. Testing activity by concentration of 12,5%, 10%, 7,5%  and 5% in threetimesrepetition. Research result: Ethanol extract of tembelekan leafwith concentration 12,5%, 10% and 7,5% resulted inhibitory zone of the growth of S.typhi, respectively for 6,6 mm, 5,3 mm and 2,6 mm. Conclution:The conclusion of the research was ethanol extract of tembelekan leaf has antibacterial activity against S.typhi.Keywords :tembelekan leaf (L.camara L.), S.typhi, infection
Identifikasi Candida albicans pada Wanita Dewasa di Kota Kendari secara Makroskopis dan Mikroskopis Hartati Hartati; Maliftha Dwi Aini; Yuliyanti Yasin
MEDULA JURNAL ILMIAH FAKULLTAS KEDOKTERAN UNIVERSITAS HALU OLEO Vol 6, No 2 (2019)
Publisher : Halu Oleo University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (210.565 KB) | DOI: 10.46496/medula.v6i2.6726

Abstract

ABSTRACTBackground: Candida albicans is a major cause of invasive fungal infections and the common health problems that occur in the community. It was reported that 85-90% of C. albicans is a major cause of candidiasis vulvovaginalis (CVV) infections worldwide. Reports from the University of Manchester in England and Wayne State University in the United States of America specified that the prevalence of CVV cases in Indonesia is ranked fourth in the world with 4 million cases. Research Purposes: This research aims to determine the macroscopic and microscopic depiction of C. albicans from vaginal swab in Kendari City. Research Methods: The present research is a descriptive study conducted in adult women who visit the Clinical Laboratory Maxima Kendari to do pap smear of both with and without complaints. The total sampling technique was used for collecting 36 samples. The variables being studied consist of independent variables by macroscopically and microscopically and C. albicans is the dependent variable. Research Result The results showed that as of 36 samples of the secret vaginal, 4 samples (11.1%) were identified positive Candida sp. on direct examination with 10% KOH, 15 samples (41.7%) were positive Candida sp. resulting from gram stain test and culture of sabouraud dextrose agar, and there were 12 samples (80%) detected as positive C. albicans on biochemistry test. Conclusion: Research concluded that C. albicans can be identified by both macroscopic and microscopic analysis. As of 36 secret vaginal samples, 6 samples with complaint and 9 samples without complaint positive contain C. albicans, yet 14 samples with complaint and 7 samples without complaint do not detected C. albicans. Keywords : Candida albicans, swab vagina, macroscopic, microscopic
Co-Authors AFRIZAL AFRIZAL Agustina Rahmawati Ahmad Afiif Ahmad Ali Syauqi Ahmad Faqih Hasyim Ahmad Syakir Kurnia Ahmadi Jaya Permana Alif Rahman Habibi Arifin Allu Aslamia Rosa Atip Nurharini AYU WULANSARI Bunga Aulia Cahyo Muarif Wibowo Pratama Choliq Sabana Daffa Nur Derry Trisna Wahyuni S Dessy Yunita Destriani Destriani DIAN WULANDARI Dina Martha Fitri Doni Pranata E. Rokhminarsi Eka Aprilia Elita Rahmi Enny Sudarmonowati Enung Sri Mulyaningsih Ermawati Ermawati Fedelia Raya Feniliana Feniliana Fransischa Apryeni Haedariah Haedariah Handoyo Handoyo Hardiyanti Hardiyanti Hargiani, Fransisca Xaveria Harsasi Setyawati Herry Prasetyo I Putu Wira Putra Suherman Ihsan Hilmi Iisnawati, Iisnawati Ija Rianti Ilyas Ismail Irfan Fadhlurrohman Isman.H Iyakrus Juni Sumarmono Keysa Keysa Khairul Awaludin Lista Yul Zamrul Lukman Zain MS M Ferdiansyah Maliftha Dwi Aini Millatin Puspaningtyas Mochammad Zakki Fahmi Moh. Projo Angkasa Muh. Febriansyah Karlis Muh. Ibra Julianto Nadirah Nadirah Naofal Dhia Arkan Novi Setyasto Noviarsih Muslimah Nura Malahayati Nuraeni Abbas Nurhamidar Rahman Okky Putra Alwin Parawansah Parawansah Putri Yanuarita Sutikno Rahmalia Afriyani Renggani Renggani Reski Reski Riri Rizqiyatul Falah Satrio Wicaksono Sobrotul Imtikhanah Sri Hartati Sri Sumarni Sudirman Sudirman Sumarni Sumarni Suriati Eka Putri Suryo Adi Nugroho Suwandi Suwandi Syarifin, Andi Noor Kholidha Syska Purnama Sari Ta’adi Ta' adi Triana Setyawardani Ulfa Natsir Ulilta Muktadira Victorian, Ahmad Richard Wahyu Indra Bayu Waluyo Waluyo Yasri Hasim Yetniwati Yetniwati yuliana Galih Dyan Anggraheni Yuliyanti Yasin Yusfi, Herri Yusrianti Yusrianti Zulfiati Syahrial