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All Journal JURNAL GIZI INDONESIA Media Penelitian dan Pengembangan Kesehatan Acta Interna : The Journal of Internal Medicine Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Jurnal NERS Indonesian Journal of Biotechnology Majalah Obat Tradisional INDONESIAN JOURNAL OF PHARMACY Jurnal Farmasi Sains dan Komunitas Universa Medicina JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Jurnal Gizi Klinik Indonesia Journal Of Nursing Practice Indonesian Journal of Rheumatology JPSCR : Journal of Pharmaceutical Science and Clinical Research Ina Kidney Jurnal Pedagogi dan Pembelajaran Nutrisia JKKI : Jurnal Kedokteran dan Kesehatan Indonesia Media Farmasi Indonesia Berita Kedokteran Masyarakat Journal of Tropical Pharmacy and Chemistry

Nyoman Kertia

Departemen Ilmu Penyakit Dalam, Fakultas Kedokteran, Kesehatan Masyarakat, Dan Keperawatan, Universitas Gadjah Mada, Yogyakarta

Author-ID : 297573

Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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PENGARUH TERAPI KURKUMINOID EKSTRAK RIMPANG KUNYIT DIBANDINGKAN DENGAN NATRIUM DIKLOFENAK TERHADAP FUNGSI GINJAL PENDERITA OSTEOARTRITIS Kertia, Nyoman; Asdie, Ahmad Husain; Rochmach, Wasilah; -, Marsetyawan
Media Penelitian dan Pengembangan Kesehatan Vol 21, No 4 Des (2011)
Publisher : Badan Penelitian dan Pengembangan Kesehatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/mpk.v21i4 Des.81.

Background: Osteoarthritis is a joint disease most often found in the community. Patients with osteoarthritis are frequently drink non steroidal anti inflammatory drugs such diclofenac sodium. Data has shown too many side effects of diclofenac sodium especially to the kidney function. A research data in Malang shows that people who use herbs were 476 persons in city area and 580 persons in distric area per thousand patients with arthritis. Curcuma domestica Val. is one of Asia's native plants used to make herbal medicine mainly used to reduce inflammation. The purpose of this study was to assess the safety of curcuminoid from Curcuma domestica Val. rhizome extract compared to diclofenac sodium to the kidney function of patients with osteoarthritis. Methods: This was a prospective randomized open and blinded evaluation (PROBE) study. Subjects with knee osteoarthritis were divided randomly into two groups: the group who received 30 mg 3 times daily of curcuminoid from Curcuma domestica Val rhizome extrac (curcuminoid group) and group who received 25 mg 3 times daily of diclofenac sodium (diclofenac group). Assessment of results including serum blood urea nitrogen (BUN) and creatinine level was performed before and after 4 weeks period of treatment. Data analysis compared the change of those levels in each group during the treatment period by student t test analysis. Results: In the curcuminoid group there was no significant decrease of serum BUN level (p=0.52) and there was a significant decrease of serum creatinine level (p=0.03). In the diclofenac group there was a significant increase of serum BUN level (p<0.01) and no significant increase of serum creatinine level (p=0.39). Increasing the serum level of BUN and creatinine in diclofenac group were significantly different compared to decreasing of those level in the curcuminoid group with p=0.01 and p=0.03 respectively. Conclusion: Treatment with Curcuminoid from Curcuma domestica Val. rhizome extract was significantly decreased the serum BUN and creatinin level compared to those increased level in diclofenac sodium treatment. AbstrakLatar belakang: Osteoartritis merupakan penyakit sendi yang paling banyak dijumpai di masyarakat. Pasien osteoartritis sering menggunakan obat anti inflamasi non steroid seperti natrium diklofenak. Data menunjukkan banyaknya efek samping natrium diklofenak khususnya terhadap fungsi ginjal. Data penelitian di Kotamadya dan Kabupaten Malang menunjukkan bahwa penduduk yang menggunakan jamu masing-masing adalah 476 orang dan 580 orang per seribu pasien. Kunyit (Curcuma domestica Val.) adalah salah satu tumbuhan asli Asia yang biasa dibuat jamu yang utamanya digunakan untuk mengurangi peradangan. Tujuan penelitian ini adalah untuk menilai keamanan terapi kurkuminoid ekstrak rimpang kunyit dibandingkan dengan natrium diklofenak terhadap fungsi ginjal penderita osteoartritis. Metode: Penelitian ini dirancang sebagai prospective randomized open and blinded evaluation (PROBE). Subjek dengan osteoartritis lutut yang memenuhi syarat dan bersedia ikut dalam penelitian ini dibagi menjadi dua kelompok secara random yaitu kelompok yang mendapatkan terapi kurkuminoid ekstrak rimpang kunyit 30 mg diminum 3 kali sehari (kelompok kurkuminoid) dan kelompok yang mendapatkan terapi natrium diklofenak 25 mg diminum 3 kali sehari (kelompok diklofenak). Penilaian hasil terapi yang meliputi kadar blood urea nitrogen (BUN) dan kreatinin serum dilakukan sebelum dan setelah 4 minggu terapi. Analisis data untuk membandingkan perubahan kadar BUN dan kreatinin pada masing-masing kelompok perlakuan dilakukan dengan student t test. Hasil: Pada kelompok yang mendapat terapi kurkuminoid ekstrak rimpang kunyit terjadi penurunan kadar BUN serum yang tidak bermakna (p=0,52) dan penurunan kadar kreatinin serum secara bermakna (p=0,03). Pada kelompok yang mendapat terapi natrium diklofenak terjadi peningkatan kadar BUN serum secara bermakna (p<0,01) dan peningkatan kadar kreatinin serum yang tidak bermakna (p=0,39). Peningkatan kadar BUN dan kreatinin serum pada terapi natrium diklofenak berbeda bermakna dengan penurunan kadarnya pada terapi kurkuminoid (p=0,01 dan p=0,03). Kesimpulan: Terapi kurkuminoid ekstrak rimpang kunyit menurunkan kadar BUN dan kreatinin serum penderita osteoartritis secara bermakna dibandingkan dengan peningkatan kadarnya pada terapi dengan natrium diklofenak.

Efek konsumsi yoghurt probiotik terhadap kadar low density lipoprotein pada penyandang diabetes mellitus tipe 2 Yuliani, Kartika; Kertia, Nyoman; Lestari, Lily Arsanti
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 8, No 1 (2019)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background : As one of important markers of cardiovascular complication in patients with type 2 diabetes mellitus, low density lipoprotein (LDL) shall be maintained to be in normal range. Based on previous research, consumption of probiotic yogurt contains Lactobacillus acidophilus and Bifidobacterium animalis subsp. Lactis is presumed can improve LDL in patients with type 2 diabetes mellitus but the scientific evidence is still few.Objectives: To investigate the effect of probiotic yogurt on LDL in patients with type 2 diabetes.Methods: This study was double blinded randomized controlled trial which was conducted on 32 patientss with type 2 diabetes mellitus. Subjects were divided randomly into 2 groups and given 4 weeks intervention. Subjects in control group were given conventional yogurt while subjects in intervention group were given probiotic yogurt contains L. acidophilus LA5 and B. animalis subsp. Lactis Bb12. Food intake data was collected 4 times using 24-hour recall method during intervention period. LDL of subjects was measured before and after intervention.Results: There was no significant difference between LDL before and after intervention in control group (128 â€“ 148.5 mg/dL) and intervention group (130 â€“ 120.5 mg/dL). Meanwhile, LDL after intervention in control group and intervention group were significantly different (p<0.05). LDL between energy and macronutrients intake categories were not significantly different.Conclusion: Probiotic yogurt has a better LDL reduction effect in patients with type 2 diabetes mellitus than conventional yogurt, although the reduction is not significant.

Efek konsumsi yogurt terhadap glukosa darah puasa pada penyandang diabetes melitus tipe 2 Nuriannisa, Farah; Kertia, Nyoman; Lestari, Lily Arsanti
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 8, No 1 (2019)
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Background: Generally, patients with type 2 diabetes mellitus (T2D) have dysbiosis condition. Dysbiosis can increase oxidative stress that leads to hyperglycemia. Previous researches showed that yogurt consumption can reduce blood glucose in T2D, so it can be used as an alternative healthy snack for T2D patients.Objectives: To investigate the effects of probiotic and conventional yogurt with dosage 100ml/day on fasting blood glucose (FBG) in T2D patientsMethods: Randomized controlled trial, double blind with pre-post group design. The 30 T2D patients from 3 publics health centre in Yogyakarta, were assigned to two groups. Each group, either control or intervention group, received 100 ml/d of yogurt for 4 weeks. FBG samples was assessed before and after intervention periodResults: FBG significantly decreased in both group, which was -27 mg/dL in control group (p<0.05) and -19 mg/dL in intervention group (p<0.05). No significant difference in FBG change between intervention and control group, but control group has greater reduction in FBG compared to intervention group. Conclusion: Conventional yogurt has no significant difference effect in FBG change compared to probiotic yogurt.Â

Role of nuclear factor-κB (NF-κB) on mind body interventions (MBIs) in patients with systemic lupus erythematosus (SLE) Achadiono, Deddy Nur Wachid; Kertia, Nyoman; Asdie, Achmad Husain; Riyanto, Bambang Udji Djoko
Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Vol 52, No 3 (2020)
Publisher : Journal of the Medical Sciences (Berkala Ilmu Kedokteran)

Mind body interventions (MBIs) are exercise that emphasizes the use of brain and body to assist the healing process and to manage symptoms in order to improve wellbeing. The MBIs are expected to be a supporting therapy for patients with autoimmune disease such as systemic lupus erythematosus (SLE), to improve patients’ activities, reduce fatigue, stress, and depression.One type of MBIs that could be potentially applied in Indonesia is latihan pasrah diri (LPD). Studies showed that MBIs can affect the expression of pro- and anti-inflammatory mediators. Nuclear factor-κB(NF-κB) is a transcription factor that controls gene expression related to many physiological responses including inflammation, proliferation, cell differentiation, and apoptosis. NF-κB can be activated through canonical and alternative pathway. This literature review aimed to identify the role of NF-κB as consequence of practicing MBIs in SLE patients. We searched for relevant publications in the MEDLINE/Pub Med and Google Scholar with no date restriction. This review revealed that abnormal NF-κB could mediate autoimmune condition in SLE pathogenesis. MBIs are expected to be a supportive treatment that can help to control NF-κB expression in SLE patients. LPD as an Indonesian original MBI is expected as a suitable techniques that can be applied in patients with SLE in Indonesia. Further studies on the effect of LPD on NF-κB expression in patients with SLE need to be further explored.

PENERAPAN MODEL PEMBELAJARAN KOOPERATIF TIPE ROLE PLAYING UNTUK MENINGKATKAN HASIL BELAJAR SISWA KELAS X AP1 PADA PELAJARAN PPKN Kertia, Nyoman
Jurnal Pedagogi dan Pembelajaran Vol 2, No 1 (2019)
Publisher : Universitas Pendidikan Ganesha

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23887/jp2.v2i1.17604

Penelitian ini bertujuan meningkatkan hasil belajar mata pelajaran PPKn siswa kelas X AP1 SMK Negeri 1 Sukasada semester genap tahun pelajaran 2017/2018 dengan penerapan model pembelajaran Kooperatif tipe Role playing. Jenis penelitian ini adalah Penelitian Tindakan Kelas (PTK). Penelitian dilaksanakan sebanyak 2 siklus. Subyek penelitian adalah siswa kelas X AP1 SMK Negeri 1 Sukasada tahun pelajaran 2017/2018 semester genap yang berjumlah 30 orang. Data dianalisis menggunakan kuantitaif dan kualitatif. Berdasarkan hasil penelitian didapatkan terjadi peningkatan hasil belajar PPKn siswa siklus 1 dengan materi ?Wawasan Nusantara dalam konteks Negara kesatuan Republik Indonesia? pada siklus I dengan rata-rata sebesar 74,8 yang termasuk ke dalam kategori kurang, sedangkan ketuntasan klasikal sebesar 30 %. Sedangkan pada materi yang sama siklus II rata-rata PPKn siswa sebesar 85,81 yang termasuk klasifikasi baik, dan ketuntasan klasikal sebesar 100% dari 30 siswa. Dari analisis data di atas model pembelajaran kooperatif tipe Role Playing terbukti efektif dalam meningkatkan hasil belajar siswa. Kata Kunci: Hasil Belajar PPKn, Model Pembelajaran Kooperatif tipe Role Playing

QUALITY OF LIFE OF PATIENTS PRESCRIBED WITH HERBAL MEDICINE Dyah Aryani Perwitasari; Nur Mahdi; Mustika Muthaharah; I Nyoman Kertia
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 13, No 2 (2016)
Publisher : Sanata Dharma University

Herbal medicine has been an alternative treatment, instead of modern medicines. However, some of patients could experience adverse drug reaction (ADR) due to the use of herbal medicines. The ADR can decrease patients quality of life (QoL). Objective. This study was aimed to understand the QoL of patients prescribed with herbal medicines. Methods. Patients prescribed with herbal medicines as complementary treatment, in two Public Health Centers of Yogyakarta were recruited. The patients were prescribed with herbal medicines one year before this study was started. Naranjo algorithm was used to identify the ADR. The SF-36 questionnaire was given to the patients as the instrument to measure patients QoL. Results. There were 47 patients participated in this study. Most of the patients are female (62.5%).Ten patients experienced ADR. There are no significant differences between QoL domains in patients experienced ADR and those without ADR. However, the scores of physical function, role physical, general health, social function, role emotional, and mental health in patients without ADR are higher than those with ADR ( p0.05) . Conclusion. There are no significant differences of QoL between patients with and without ADR. In general, the QoL of patients without ADR is higher than those with ADR.

Ability of Curcuminoid from Curcuma domestica Val. in Reducing the Secretion of Reactive Oxygen Intermediates by Synovial Fluid Monocytes in Patients with Osteoarthritis Nyoman Kertia; Ahmad Husain Asdie; Wasilah Rochmah; M. Marsetyawan
Indonesian Journal of Biotechnology Vol 16, No 2 (2011)
Publisher : Universitas Gadjah Mada

Increasing the secretion of reactive oxygen intermediates (ROI) by monocytes in the synovial fluid is anindicator to determine the severity of joint inflammation. Previous studies have shown that curcumin inhibitthe osteoarthritis progression with its ability to inhibite the activity of the nitric oxide synthase (NOS) enzymefrom macrophages. In this prospective randomized open end blinded evaluations = PROBE study, 80 patientswith knee osteoarthritis were eligable. The subject were devided in to two group: group who received 3 x 30mg of curcuminoid from Curcuma domestica Val. extract (curcuminoid group) and group who received 3 x 25mg of diclofenac sodium (diclofenac group) as comparison. The treatment was for 4 weeks time. The secretionof ROI by sinovial fluid monocytes was calculated by scoring the amount of formazan formation after neutralred staining in nitrobleu tetrazolium reduction assay. The result of this study showed that the secretion of ROIby synovial fluid monocytes was significantly decreased in both groups (p <0.001) respectively. There wasno significant difference in decreasing of ROI secretion of synovial fluid monocytes between both treatmentgroups (p = 0.92).

ANTI-INFLAMMATORY ACTIVITIES OF TEMULAWAK, GINGER, SOYBEAN AND SHRIMP SHELL EXTRACTS IN COMBINATION COMPARED TO DICLOFENAC SODIUM Nyoman Kertia; Deddy Nur Wachid Akhadiono; Ayu Paramaiswari; Arina Syarifa Fadlilah; Hangga Harinawantara
Acta Interna The Journal of Internal Medicine Vol 1, No 1 (2011): Acta Interna The Journal of Internal Medicine
Publisher : Faculty of Medicine Universitas Gadjah Mada

ABSTRACT Background: The prevalence of osteoarthritis (OA) in the community is high. This disease is the second most common cause of physical disability worldwide. Pain in OA is caused by several factors, such as inflammation. Non steroidal anti-inflammatory drugs (NSAIDs) were the most common drugs given worldwide to reduce pain in OA. NSAIDs were also associated with a high incidence of gastrointestinal side effects. An alternative to manage this problem is by using the combination of Curcuma xantorrhyza Roxb. (commonly known as temulawak) extract, ginger (Zingiber officinale) extract, soybean (Glycine max), and shrimp shell. Curcuma xantorrhyza contains curcumin which has anti-inflammatory effect by suppressing cyclo-oxygenase (COX-2) enzyme activity, suppressing lipo-oxygenase enzyme activity, and play a role as a free radical scavenger. Ginger can inhibit COX-2 activity in PGE-2 production. Shrimps shell contains glucosamine and chondroitin which can increase proteoglycan in articular chondrocytes and inhibit COX-2 synthesis. Isoflavone in soybean can inhibit articular cartilage degradation and COX-2 synthesis.Study Aims: The purpose of this study is to compare the effect of the combination to diclofenac sodium in reducing synovial fluid leukocyte count and joint pain in patients with osteoarthritis.Study Method:This study was a prospective randomized open end blinded evaluation (PROBE). Twenty one patients with knee osteoarthritis diagnosed by American College of Rheumatology criteria were included in this study. Patients were randomized into two groups to receive either diclofenac sodium 25 mg (control group) or the combination of Curcuma xantorrhyza extract 50 mg, ginger extract 100 mg, shrimp shell 100 mg, and soy bean flour 50 mg (treatment group) three times daily for 14 days. Independent t-tests and Mann-Whitney-Wilcoxon tests were used to evaluate changes between prior and post intervention.Results: There were significantly reduction of synovial fluid leukocyte count in both control group (p=0.017) and treatment group (p=0.008) respectively. The reduction of synovial fluid leukocyte count was not significantly different between control group and treatment group (p=0.929). There were significant improvement of joint pain (VAS score) in both control group (p=0.012) and treatment group (p<0.001). The reduction of VAS score was not significantly different between diclofenac group and treatment group (p=0.607).Conclution: These results indicate that the evicacy of this combiation was not significantly different with diclofenac sodium in reducing the synovial fluid leukocyte count and joint pain in patients with osteoarthritis.Keywords: osteoarthritis, Synovial fluid leukocyte count, Pain, VAS, Diclofenac sodium,Combinaion of curcuma, ginger, shrimp shell and soybean.

Relationship Between Systemic Lupus Activity Measurement (SLAM) Score and Mortality in Systemic Lupus Erytemathosus (SLE) Inpatients Ayu Paramaiswari; Nyoman Kertia; Deddy Wachid Achadiyono
Acta Interna The Journal of Internal Medicine Vol 4, No 1 (2014): Acta Interna The Journal Of Internal Medicine
Publisher : Faculty of Medicine Universitas Gadjah Mada

ABSTRACTBackground: Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disorder that can be severe and life threatening. Mortality in SLE may due to lupus activity or long-term sequel. Systemic Lupus Activity Measurement (SLAM) score is a tool that can count lupus disease activity inpatients.Aims: To analyze the relationship between SLAM score and mortality in lupus inpatients.Methods: Retrospective cohort study used for reaching objective of the study. Lupus inpatients was used as research population. Medical record was used as study data collection over periods of 2006 until 2011. Independent variable was a SLAM score. The cut point of SLAM score was made based on the mean of SLAM score (16.7 point score). Dependent variable was mortality.Results: There were differences between number of ACR criteria fi ndings, pneumonia, heart rate with SLAM score (p value 0.001; 0.001; 0.002 respectively).There was a difference of median survival between less and more than 16.7 point score, 45 and 28 respectively (p 0.034). There was a relationship between SLAM score (more than 16.7 point score) and mortality HR 2.78 (96% CI 1.01-7.53). There was a difference of mortality incidence between more and less than 16.7 point score, 0.35 and 0.10 respectively. There was a relationship between SLAM score (more than 16.7 point score) and mortality RR 3.5 (95% CI). Mortality in lupus inpatients was 23%.Conclusion: There was a relationship between SLAM score and mortality on lupus inpatients.Keywords: SLE, SLAM, Mortality

Maxillary Reconstruction Timing in Severe Systemic Lupus Erythematous (SLE) Patient with Bone Destruction due to Invasive Aspergillosis: Case Report Yulyani Werdhiningsih; Ayu Paramaiswari; Deddy Nur Wachid Achadiono; Nyoman Kertia
Acta Interna The Journal of Internal Medicine Vol 10, No 2 (2020): Acta Interna The Journal of Internal Medicine
Publisher : Faculty of Medicine Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/actainterna.62845

Severe Systemic Lupus Erythematosus patient was in the third of 28-days-cycle cyclophosphamide chemotherapy when the early symptoms of aspergillus infection occurred. This developed into extensive cranial bone damage. It was planned to get a biopsy and debridement for bone and soft tissue to diagnose and therapy palate osteonecrosis, followed by reconstruction surgery. This case report aimed to report the successful management of a severe patient on chemotherapy undergoing several operations so that the SLE aspergillosis is optimally managed.

Co-Authors Abdul Khairul Rizki Purba Mustofa Indwiani Astuti Achadiono, Deddy Achadiono, Dedy Nurwachid Ahmad Husain Asdie Ahmad Husain Asdie Ahmad Husain Asdie Arif Nurrochmad Arif Prassetyo Arina Syarifa Fadlilah Asdie, Achmad Husain Ayu Paramaiswari Ayu Paramaiswari Baiq R Rhadianaa Bambang Udji Djoko Rianto Bambang Udji Djoko Riyanto, Bambang Udji Djoko Danang ., Danang Deddy Nur Wachid Deddy Nur Wachid Achadiono Deddy Nur Wachid Akhadiono Deddy Wachid Achadiyono Dewa Ayu G. N. Dewa Ayu G. N., Dewa Ayu Dyah Ariani Perwitasari Dyah Aryani Perwitasari Ema Madyaningrum Endang Mahati Eny Catur, Eny F, Melani Farah Nuriannisa Gede Kambayana Gunawan, I Made Alit Hangga Harinawantara Haslinda Haslinda Haslinda Haslinda, Haslinda Heru Yulianto I Dewa Putu Pramantara I Made Alit Gunawan I Made Alit Gunawan Ika Puspitaningrum Imono A.D., Imono Indwiani Astuti Irwan Supriyanto Kartyanto, Adhita Khasana, Tri Mei Krishnan, P N Lily Arsanti Lestari M. Marsetyawan Mae Sri Hartati Wahyuningsih Maria Caecilia Nanny Setiawati Maria Caecilia Setiawati Marsetyawan -, Marsetyawan Marsetyawan Marsetyawan Marsetyawan Marsetyawan Metalia Puspitasari Mohammad Robikhul Ikhsan Mufrod ., Mufrod mustika muthaharah Mustika Muthaharah Mustika Muthaharah muthaharah, mustika N. Setiawati, M. Caecilia Nastiti Hemas M. Nastiti Hemas M., Nastiti Hemas Nugroho, Dhite Nunu N Madjid Nur Arfian Nur Mahdi Nurrochmad, Arif P N Krishnan Poerwono Rahardjo Pratiwi, Woro Rukmi Probosuseno Probosuseno Probosuseno Probosuseno, Probosuseno Rochmach, Wasilah Ronny T Wirasto Sinarta, Armin SRI SETIYARINI, SRI Srinalesti Mahanani Sugeng Sugeng Supanji, Supanji Susini R Sari Tri Mei Khasana W.N., Meika Wachid, Deddy Nur Wasilah Rochmah Wasilah Rochmah Wasilah Rochmah Widhiarta, Putu Raka Wiwekananda, Ketut Shri Satya Wiwin Lismidiati Yenny Kandarini Yogiswara, Komang Satvika Yolanda Dyah Kartika Yuliani, Kartika Yulyani Werdhiningsih Z, Ikawati Zulies Ikawati

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