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ANALISIS AKTIVITAS ANTIOKSIDAN JAMUR ENDOFITIK DDP YANG BERKOLONISASI DENGAN DAUN DEWA (GYNURA SEGETUM) DENGAN METODE DPPH (2,2-DEFENIL-1-PIKRILHIRAZIL) Nur Meisinca, Dzulhijjah; Riga, Riga; Adia Silvani, Mauline; Oktria, Wandi; Nasra, Edi; Kurniawati, Desi; Oktavia Dewita, Febby; Dwi Rahma Doni, Deani; Khairiyah, Ghina
Jurnal Farmamedika (Pharmamedika Journal) Vol 9 No 2 (2024): Jurnal Farmamedika (Pharmamedica Journal)
Publisher : Sekolah Tinggi Teknologi Industri dan Farmasi Bogor

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47219/ath.v9i2.371

Abstract

Daun dewa (Gynura segetum) tergolong ke dalam famili Asteraceae dan juga termasuk sebagai tanaman obat untuk mengatasi berbagai penyakit. Daun dewa menghasilkan senyawa aktif yang memiliki bioakivitas, salah satunya bersifat antioksidan. Senyawa antioksidan dari tumbuhan ini dapat dieksplorasi lebih lanjut melalui jamur endofitik. Tujuan dari penelitian ini yaitu untuk menganalis metabolit sekunder dan menguji aktivitas antioksidan dari jamur endotifik DDP yang berkolonisasi dengan daun dewa menggunakan media nasi sebagai media pertumbuhan. Hasil analisis fitokimia membuktikan bahwa ekstrak etil asetat (EtOAc) jamur endofitik DDP menunjukkan hasil positif terpenoid dan alkaloid. Analisis aktivitas antioksidan menggunakan metode DPPH (2,2-Defenil-1-Pikrilhirazil) juga dilakukan pada studi ini. Nilai IC50 yang diperoleh yaitu 77,83 ppm yang menunjukkan ekstrak jamur endofitik DDP memiliki aktivitas antioksidan yang kuat.
POTENSI INTERAKSI OBAT PADA PASIEN HIPERTENSI DENGAN PENYAKIT PENYERTA DI RSUD PREMBUN: POTENTIAL DRUG INTERACTIONS IN HYPERTENSION PATIENTS WITH COMORBID DISEASES AT PREMBUN HOSPITAL Kurniawati, Desi; Widiastuti, Tri Cahyani; Khuluq, Khusnul
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1762

Abstract

In the treatment of hypertension accompanied by comorbidities, there are many occurrences, so the potential for polypharmacy is very large, which causes the possibility of drug interactions. Drug interactions cause various problems such as decreased therapeutic effects, increased toxicity, or altered pharmacological effects of a drug.This study aims to describe the potential interaction of hypertension drugs in inpatients at Prembun Hospital for the 2023 period. This research is descriptive research by collecting data retrospectively. Data on the use of antihypertensive drugs and data on inpatient visits were obtained from the Inpatient Institution of Prembun Hospital for the 2023 Period. Out of a total of 100 patients, there were 93 interactions (93%). There were 3 interactions, namely the most severe level, namely moderate interactions as many as 150 interactions (58.3%) occurred in drugs between Aspirin and Amlodipine, the severity of minor interactions as many as 71 interactions (27.6%) occurred between Amlodipine drugs and Furosemide, and the least severe level of drug interactions was major interactions as many as 36 interactions (14%) occurred between Spironolactone and Candesartan. From the results of the study, it can be concluded that there is 93% interaction in the use of hypertension drugs, and 7% there is no interaction in the use of hypertension drugs. Keywords:  Hypertension, Comorbidities, Interaction
Hubungan pemberian asi eksklusif terhadap kejadian diare Pada bayi usia 0-24 bulan Noprida, Dayana; Rostika, Silma; Kurniawati, Desi; Fatimah, Wahyu Dwi
THE JOURNAL OF Mother and Child Health  Concerns Vol. 4 No. 3 (2025): February Edition 2025
Publisher : Indonesian Public Health-Observer Information Forum (IPHORR) Kerjasama dengan Persatuan Perawat Nasional Indonesia (PPNI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56922/mchc.v4i3.682

Abstract

Background: Diarrhea is the leading cause of infant mortality and morbidity in developing countries. Diarrhea can be triggered by various factors, one of which is not exclusive breastfeeding. Infants who are exclusively breastfed until 6 months of age have fewer gastrointestinal disorders and growth disorders. Purpose: To determine the relationship between exclusive breastfeeding and the incidence of diarrhea in infants aged 0-24 months. Method: Quantitative research with cross-sectional research design. The population in this study were all children aged 0-24 months in the Gisting Health Center Working Area, with a sample of 66 respondents using the total sampling technique. Data collection using questionnaire. Univariate and bivariate analysis (chi square test). Results: It was found that 35 (53.0%) respondents practiced exclusive breastfeeding. and 52 (78.8%) respondents did not experience diarrhea. Conclusion: There is a relationship between exclusive breastfeeding and the incidence of diarrhea in infants aged 0-24 months at the Gisting Health Center in 2024 (p-value = 0. 003). Suggestion: Health workers can increase health promotion, especially regarding exclusive breastfeeding as an effort to prevent diarrhea in infants and provide education to mothers and families regarding additional food for babies.   Keywords: Diarrhea incidence; Exclusive breastfeeding; Infants aged 0-24 months.   Pendahuluan: Diare merupakan penyebab utama terjadinya mortalitas dan morbiditas pada bayi di negara berkembang. Diare dapat dipicu oleh berbagai faktor salah satunya ialah tidak dilakukannya pemberian ASI eksklusif. Bayi yang diberikan ASI eksklusif sampai usia 6 bulan lebih sedikit mengalami gangguan gastrointestinal dan gangguan pertumbuhan. Tujuan: Untuk mengetahui hubungan pemberian ASI eksklusif terhadap kejadian diare pada bayi usia 0-24 bulan. Metode: Penelitian kuantitatif dengan rancangan penelitian cross-sectional. Populasi dalam penelitian ini adalah semua anak usia 0-24 bulan Wilayah Kerja Puskesmas Gisting, dengan sampel yang digunakan sebanyak 66 responden menggunakan teknik total sampling. Pengumpulan data menggunakan lembar keusioner. Analisis secara univariat dan bivariat (uji chi squre). Hasil: Diketahui sebanyak 35 (53.0%) responden melakukan pemberian ASI eksklusif. dan sebanyak 52 (78.8%) responden tidak mengalami kejadian diare. Simpulan: Ada hubungan pemberian ASI eksklusif terhadap kejadian diare pada bayi usia 0-24 bulan di Puskesmas Gisting tahun 2024 (p-value =0. 003). Saran: Bagi tenaga kesehatan dapat meningkatkan promosi kesehatan terutama mengenai pemberian ASI eksklusif sebagai upaya preventif diare pada bayi dan pemberian edukasi pada ibu dan keluarga mengenai makanan tambahan untuk bayi.
The Role of Auditor Reputation in Moderating the Effect of CSR and Earnings Management on Tax Avoidance Kurniawati, Desi; Pertiwi, Indah
IJESS International Journal of Education and Social Science Vol. 5 No. 2 (2024): VOL 5 NO 2 OCTOBER 2024
Publisher : INTERNATIONAL PENELITI EKONOMI, SOSIAL, DAN TEKNOLOGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56371/ijess.v5i2.368

Abstract

This study analyzed the effect of earning management and corporate social responsibility disclosure on tax avoidance moderated by auditor reputation. This study employed panel data from 12 Indonesia's mining companies from 2015 – 2019. This study used the effective tax ratio (ETR) as the proxy of tax avoidance. By employing the regression panel data analysis, this study found that earnings management has a negative and significant effect on ETR. Meanwhile, this study revealed that CSR could not affect the ETR. On the other hand, this study found that auditor reputation has a negative moderated role in the CSR's effect on ETR. Nevertheless, this study failed to prove any moderating role of auditor reputation in earnings management's effect on ETR. These results revealed that earnings management in mining companies was carried out in the context of tax avoidance.
The linguistic features of texting and their utilization in a WhatsApp group of English major students Kurniawati, Desi; Rusfandi, R; Liskinasih, Ayu
Leksika: Jurnal Bahasa, Sastra dan Pengajarannya Vol 19, No 1 (2025)
Publisher : Universitas Muhammadiyah Purwokerto

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30595/lks.v19i1.24253

Abstract

This research investigates the linguistic features present in text messaging among students enrolled in an English literature program. The study specifically examines the WhatsApp group "Ellite Students Assemble," utilizing the classification of linguistic features developed by Ali, Hasnain, and Beg (2021) and exploring the factors that influence the use of textese. This research employs a qualitative design to analyze linguistic characteristics in digital communication, particularly on WhatsApp. The analysis encompasses morpho-syntactic and phonological features, revealing a complex phenomenon of language adaptation. A detailed examination of WhatsApp texts highlights the occurrence of each linguistic feature, providing insights into the observed patterns and tendencies. The study identifies key influences on texting styles, including informality, speed, efficiency, and creative expression. Interviews with five active participants elucidate the reasons behind their textese choices, demonstrating that individuals adjust their texting styles based on considerations of formality, efficiency, and creative expression. The results illustrate the dynamic nature of language within the WhatsApp context among English literature students. An understanding of these linguistic features and their influences offers valuable insights for educators, researchers, and language enthusiasts, contributing to a comprehensive understanding of contemporary communication practices.
The Influence of Stakeholder Pressure and Audit Quality on Sustainability Performance Budi, Saksono; Kurniawati, Desi
IJESS International Journal of Education and Social Science Vol. 6 No. 1 (2025): VOL 6 NO 1 APRIL 2025
Publisher : INTERNATIONAL PENELITI EKONOMI, SOSIAL, DAN TEKNOLOGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56371/ijess.v6i1.437

Abstract

The influence of stakeholder pressure and audit quality on sustainability performance. The purpose of this study is to examine the relationship between stakeholder pressure and Sustainability Performance, to examine the relationship between audit quality and Sustainability Performance. The research was conducted using associative quantitative methods. The type of data uses secondary data. The population in this study were Primary Consumer Goods Sector Manufacturing Companies listed on the Indonesia Stock Exchange (BEI) index from 2017 to 2022 as many as 12 companies using the company's financial statements listed on theBEI. The sample determination method in this study used purposive sampling of 72 samples. The results of the study can be concluded that stakeholder pressure affects Sutainability Performance and Audit Quality affects Sutainability Performance. In this study also tested the variables of stakeholder pressure and audit quality together on Sutainability Performance Based on the test results, the variables of stakeholder pressure and audit quality together have an effect on Sutainability Performance. As a result of this research, it is suggested that companies should also attach importance to knowledge, expertise and innovation in the field of sustainability so as to give companies a competitive advantage in adopting and implementing sustainable practices. Accurate and transparent information about the company's sustainability efforts can also increase trust and support from stakeholders.
The Influence of Managerial Ownership on Company Value in Manufacturing Companies Kurniawati, Desi; Erliana, Erliana; Febriyanto, Muhammad Ikhsan; Yulyanah, Yulyanah
IJESS International Journal of Education and Social Science Vol. 6 No. 1 (2025): VOL 6 NO 1 APRIL 2025
Publisher : INTERNATIONAL PENELITI EKONOMI, SOSIAL, DAN TEKNOLOGI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56371/ijess.v6i1.446

Abstract

The purpose of this study is to determine the Effect of Managerial Ownership on Company Value. This study uses a descriptive quantitative approach with data collection techniques using secondary data. The study population includes companies listed on the Indonesia Stock Exchange in 2020-2023. Sampling in this study used the purposive sampling method, so that a sample of 248 research samples was obtained. The data used in this study uses secondary data obtained from the annual report of mining companies. The data analysis method used is multiple linear regression analysis using the Eviews 10 program. The results of the study Managerial Ownership has a positive effect on Company Value.
PELATIHAN PENGISIAN SPT TAHUNAN BADAN PADA PT. PILAR TEKNOLOGI SOLUSI Hakim, Lukmanul; Kurniawati, Desi; Sunanto, Ghea Astrid
Pengabdian Kepada Masyarakat Indonesia SEAN (ABDIMAS SEAN) Vol. 3 No. 01 (2025): Pengabdian Kepada Masyarakat Indonesia SEAN (ABDIMAS SEAN), Februari 2025
Publisher : SEAN Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58471/abdimassean.v3i01.633

Abstract

Kegiatan Pengabdian Kepada Masyarakat ini bertujuan untuk meningkatkan pemahaman dan keterampilan peserta dalam bidang perpajakan, khususnya terkait pengisian Surat Pemberitahuan Tahunan (SPT) Pajak Penghasilan (PPh) Badan. Program ini dilaksanakan di PT. Pilar Teknologi Solusi, Cipondoh, Kota Tangerang, dan dirancang untuk menjawab tantangan minimnya pemahaman pengusaha pemula terhadap kewajiban perpajakan. Metode pelaksanaan meliputi ceramah, tutorial, diskusi, dan praktik langsung, dengan fokus pada pengenalan peraturan perpajakan, penggunaan sistem perpajakan digital, dan simulasi pengisian SPT. Hasil kegiatan menunjukkan peningkatan yang signifikan dalam pengetahuan dan keterampilan peserta, terutama dalam memahami aturan PPh Pasal 4 ayat (2), penggunaan sistem pelaporan pajak online, dan pengisian SPT dengan benar. Dampak positif juga terlihat pada perubahan pengelolaan perpajakan di perusahaan, di mana pencatatan keuangan dan pelaporan pajak menjadi lebih terstruktur. Meskipun menghadapi kendala berupa tingkat pemahaman awal peserta yang beragam dan adaptasi terhadap teknologi, solusi berupa bimbingan tambahan berhasil mengatasi tantangan tersebut. Kegiatan ini diharapkan dapat mendorong peserta untuk lebih siap menghadapi kewajiban perpajakan secara mandiri, sekaligus berkontribusi dalam menciptakan budaya sadar pajak di Indonesia.
PENGARUH INTELLECTUAL CAPITAL TERHADAP KINERJA KEUANGAN SEKTOR PERBANKAN SYARIAH YANG TERDAFTAR DI BURSA EFEK INDONESIA Kurniawati, Desi
Jurnal Ilmiah Publika Vol 11 No 2 (2023): Jurnal Ilmiah Publika
Publisher : Faculty of Social and Political Sciences, Universitas Swadaya Gunung Jati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33603/.v11i2.8873

Abstract

This research aims to analyze the influence of Intellectual Capital (VAHU, STVA and VACA) as an independent variable on Financial Performance as measured by Net Profit Margin (NPM). This research uses a sample of six Islamic banks listed on the Indonesian Stock Exchange for the 2011-2022 period. The sampling method used was the purposive sampling method. The empirical results of this research show that partially, the results of the t test explain that the influence of the Intellectual Capital variables (VAHU, STVA and VACA) on Financial Performance, only the STVA variable has a significant negative effect, while the other two variables (VAHU and VACA) do not have significant influence on financial performance.
HUBUNGAN PENGGUNAAN MEDIA SOSIAL DENGAN KUALITAS INTERAKSI SOSIAL PADA REMAJA DI SMP NEGERI 1 BANGUN REJO Fatimah, Wahyu Dwi; Yogaswari, Yosinia; Kurniawati, Desi
Jurnal Ilmiah Kesehatan Vol 14, No 2 (2025): Jurnal Ilmiah Kesehatan
Publisher : Universitas Muhammadiyah Pringsewu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52657/jik.v14i2.3041

Abstract

Perkembangan teknologi saat ini semakin meningkat, salah satunya dengan adanya penggunaan media sosial. Pengguna media sosial terbanyak salah satunya didominasi oleh para remaja. Perkembangan tekonologi ini juga mengubah cara remaja bermain, belajar, dan bersosialisasi. Remaja yang sulit mengontrol diri sendiri cenderung menggunakan media sosial secara berlebihan. Tujuan dari penelitian ini untuk mengetahui hubungan antara penggunaan media sosial dengan kualitas interaksi sosial pada remaja di SMP Negeri 1 Bangun Rejo. Desain penelitian ini menggunakan korelasional dengan pendekatan cross-sectional. Responden pada penelitian ini sebanyak 211 remaja di SMP Negeri 1 Bangun Rejo, dengan teknik purposive sampling. Peneliti menggumpulkan data menggunakan kuisioner dengan uji analisis chi-square. Hasil penelitian didapatkan terdapat hubungan yang signifikan antara penggunaan media sosial dengan kualitas interaksi sosial remaja (p-value = 0.000). Dimana penggunaan jejaring sosial lebih banyak digunakan, dengan interaksi sosial kurang baik. Maka dapat disimpulkan terdapat hubungan antara penggunaan media sosial dengan kualitas interaksi sosial pada remaja di SMP Negeri 1 Bangun Rejo. Diharapkan adanya pengontrolan durasi menggunakan media sosial, dengan kegiatan lain yang lebih mengutamakan interaksi remaja.