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All Journal Jurnal Pendidikan dan Pembelajaran Khatulistiwa (JPPK) PROSIDING SEMINAR KIMIA Jurnal Kimia Mulawarman Science and Technology Indonesia JURNAL ATOMIK Acta Chimica Asiana Jurnal Riset Kefarmasian Indonesia Narra J Jurnal Ilmiah Sains Jurnal Bahan Alam Terbarukan Jurnal Abdimas Mahakam
Eva Marliana, Eva
Jurusan Kimia Fakultas Matematika Dan Ilmu Pengetahuan Alam Universitas Mulawarman
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Education Energy Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Other

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UJI FITOKIMIA DAN ANTIBAKTERI EKSTRAK METANOL DAUN MACARANGA LAMELLATA WHITMORE Ramadhani, Riski Vebryanti; Marliana, Eva; Erwin, Erwin
JURNAL ATOMIK Vol 4 No 2 (2019)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (351.472 KB)

Abstract

Phytochemical test and antibacterial activity of Macaranga lamellata Whitmore have been done. This research aims to find out the secondary metabolites using Thin Layer Chromatography (TLC) and to determine antibacterial activity by paper disc method from methanol extract on Macaranga lamellata Whitmore leaf. Based on the results obtained from phytochemical tests, it was known that methanol extract contains alkaloid, flavonoid, polyphenol and terpenoid/steroid compounds. Antibacterial activity obtained Minimum Inhibitory Concentration values from methanol extract for Streptococcus sobrinus KCCM 11898 and Salmonella typhi ATCC 422 at 0-0.5%.
UJI FITOKIMIA DAN AKTIVITAS ANTIBAKTERI EKSTRAK METANOL AKAR MERUNG (Coptosapelta tomentosa) Dewi, Dynda Rosiana; Marliana, Eva; Pratiwi, Djihan Ryn
JURNAL ATOMIK Vol 4 No 2 (2019)
Publisher : Jurusan Kimia FMIPA UNMUL

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Abstract

Phytochemical tests and antibacterial activity of the roots of Merung plants (Coptosapelta tomentosa) have been done. This research aims to find out the content of secondary metabolites contained in the sample using the Thin Layer Chromatography method and to determine antibacterial activity by paper disc method from methanol extract Merung root (Coptosapelta tomemtosa). Based on results of phytochemical screening, it was known that methanol extract contained alkaloid, polyphenol, flavonoid and terpenoid/steroid. Methanol extract antibacterial activity against Propionibacterium acnes KCCM 11898 range of MIC of 0-1%. Methanol extract showed antibacterial activity against Escherichia coli bacteria ATCC 25922 range of MIC of 0-1%. From the results of the antibacterial activity test it can be concluded that the methanol extract have antibacterial activity against Propionibacterium acne KCCM 11898 and Escherichia coli ATCC 25922.
PHYTOCHEMICAL TEST ON METHANOL EXTRACT OF LEAF OF Macaranga hullettii King ex Hook.f. Rismawati, Rismawati; Marliana, Eva; Daniel, Daniel
JURNAL ATOMIK Vol 3 No 2 (2018)
Publisher : Jurusan Kimia FMIPA UNMUL

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (294.086 KB)

Abstract

Phytochemical test of Macaranga hullettii King ex Hook.f have been done. This research aims to find out the secondary metabolites using Thin Layer Chromatography (TLC) from methanol extract on Macaranga hullettii leaf. Based on results of phytochemical screening, it is known that methanol extract contains alkaloid, steroid/triterpenoid, polifenol and flavonoid compounds.
Synthesis of Silver Nanoparticle Using Bio-Reductant from Wuluh Star Fruit (Averrhoa Bilimbi L.) Extract and Their Activity as Sunscreen Hindryawati, Noor; Muhammad Marion Akbar; Eva Marliana; Ratna Kusuma
Jurnal Bahan Alam Terbarukan Vol. 14 No. 1 (2025): June 2025 [Nationally Accredited Sinta 3]
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/jbat.v14i1.16552

Abstract

Synthesis of silver nanoparticles has been carried out using AgNO3 solution as precursor with wuluh star fruit extract as bioreductant and reacted under the sunlight. The synthesized silver nanoparticles were tested for its sunscreen activity. The synthesized has been done with optimation of AgNO3 precursor and bioreductant. Based on absorbances value using UV-Vis Spectrophotometer, it is shown that silver nanoparticles from 1,5 mM AgNO3 and 25% (v/v) extract are more stable than the other variation for 4 days. The characterization of silver nanoparticles using Transmission Electron Microscope (TEM) and Particle Size Analyzer (PSA) instrument result shows the morphology of rounded silver nanoparticles with diverse sizes at range 6,9 – 27,7 nm, and with average particle size of 14,8 nm. Particle Size Analyzer (PSA) instrument shows the distribution of silver nanoparticles at range under 100 nm. Sunscreen activity of silver nanoparticles shows the SPF value of 44,14 with ultra protection type and on high level. The SPF value obtained indicates that silver nanoparticles can be applied as sunscreen.  
The Utilization of Chitosan from Maggot (Hermetia illucens) Exuvia as Edible Coating for Tomatoes (Lycopersicon esculentum) and Edible Film with the Addition of Honey as an Antibacterial Agent Daniel; Sitorus, Saibun; Pasaribu, Subur P.; Marliana, Eva; Hairani, Rita; Ruga, Ritbey; Purba, Ritson; Saleh, Chairul; Pratiwi, Djihan Ryn; Magdaleni, Agustina Rahayu; Masmur, Indra; Masmur, Hestina
Science and Technology Indonesia Vol. 10 No. 4 (2025): October
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.4.1232-1241

Abstract

The use of chitosan from maggot (Hermetia illucens) exuvia as an edible coating for tomatoes (Lycopersicon esculentum) and an edible film with honey added as an antibacterial agent was investigated. This study aimed to determine the yield of chitosan from black soldier fly (BSF, Hermetia illucens) maggot exuviae as an edible coating. The chitosan was produced from chitin by deacetylation, and its effect on the weight loss and vitamin C levels of tomatoes for 7 days after treatment was investigated. The chitosan coating was characterized by scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy. The antibacterial activity was evaluated using a disk diffusion method. The result showed that by deacetylation, conversion of chitin produced chitosan with a yield of 72% and a deacetylation degree of 75.05%. The chitosan coating significantly affected the weight loss of tomatoes, with the best concentration being 2%. However, the treatment did not significantly affect the decrease in vitamin C levels. The edible chitosan film from BSF maggot exuviae with added honey had a thickness, water content, and water vapor transmission rate of 0.156 mm, 16.9913%, and 30.45 g/m2/24 hours, respectively. SEM characterization showed a relatively dense surface structure, which was slightly smooth and porous. Regarding antibacterial activity, the edible chitosan film inhibited Staphylococcus aureus with an inhibition zone of 10.37 mm; however, Escherichia coli was not inhibited. These results suggest that chitosan from BSF maggot exuviae has potential as an effective edible coating for reducing weight loss in tomatoes despite showing limited antibacterial properties.
Pharmacological Potential of the Stem of Butterfly Root Plant (Phanera semibifida Roxb. var. semibifida): A Phytochemical, Toxicity, and Anti-Inflammatory Activity Study Ayu Mellyanti; Rita Hairani; Erwin Erwin; Winni Astuti; Medi Hendra; Eva Marliana
Jurnal Ilmiah Sains Volume 25 Issue 2, October 2025
Publisher : Sam Ratulangi University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35799/jis.v25i2.62442

Abstract

Phanera semibifida Roxb. var. semibifida, commonly known as the butterfly root plant, is one of the plants frequently used by various indigenous tribes in Kalimantan as a traditional medicinal plant. This study was conducted to identify the secondary metabolite compounds, toxicity level, and anti-inflammatory activity of the plant. Extraction of the stem of the butterfly root plant was carried out using the maceration method with methanol as the solvent, followed by partitioning with n-hexane and ethyl acetate. Phytochemical screening of the stem was performed using Thin Layer Chromatography (TLC). Toxicity testing was conducted using the Brine Shrimp Lethality Test (BSLT), and anti-inflammatory activity was evaluated based on protein denaturation inhibition in vitro using a ultraviolet-visible (UV-Vis) spectrophotometer. The crude extract of the stem was found to contain alkaloids, triterpenoids, steroids, flavonoids, and phenolics; the n-hexane fraction contained triterpenoids and steroids; the ethyl acetate fraction contained alkaloids, triterpenoids, steroids, flavonoids, and phenolics, while the aqueous fraction contained alkaloids, flavonoids, and phenolics. The toxicity levels (LC₅₀) of the crude extract, n-hexane fraction, ethyl acetate fraction, and aqueous fraction were 57.45; 158.04; 42.34; and 72.88 µg/mL, respectively, indicating toxic activity against Artemia salina L. larvae. The anti-inflammatory activity levels (IC₅₀) of the crude extract, n-hexane fraction, ethyl acetate fraction, and aqueous fraction were 124.95 µg/mL (moderate category); 161.27 µg/mL (moderate category); 99.15 µg/mL (strong category); and 143.44 µg/mL (moderate category), respectively. These results indicate that the stem of the butterfly root plant (Phanera semibifida Roxb. var. semibifida) contains bioactive compounds and has potential as a natural anti-inflammatory agent.
UJI Brine Shrimp Lethality Test (BSLT) UMBI BAWANG TIWAI (Eleutherine bulbosa (Mill.) Urb) DAN UJI TOKSISITAS AKUT FRAKSI AKTIF Lestari, Dwi; Kartika, Rudi; Marliana, Eva
Jurnal Riset Kefarmasian Indonesia Vol. 1 No. 1 (2019): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v1i1.43

Abstract

Eleutherine bulbosa (Mill.) Urb come from the Iridaceae family, this species contains secondary metabolites in the form of flavonoids and quinones. This research method includes Brine Shrimp Lethality Test (BSLT) toxicity using Artemia salina Leach larvae to determine the LC50 value. This study used experimental methods pharmacologically using a completely randomized design in the same direction pattern in the selection of test animals, 25 animals used were white mice divided into 5 groups with 5 mice per group, with 4 hours observed to find out toxic symptoms and continued observation every 24 hours to see death. Testing of BSLT results showed that ethanol extract had LC50 toxicity = 66.68 ppm (very toxic category), n-hexane fraction had LC50 toxicity = 47.64 ppm (very toxic category), chloroform fraction had LC50 toxicity = 295.1 ppm ( toxic category), and the water fraction has a toxicity of LC50 = 194.54 ppm (very toxic category). The chloroform fraction is an active fraction. Acute toxicity test LD50 value according to the calculation method of Miller Tainter Probit (187,499 mg/KgBB), the method of calculation of Thompson Weil (182,810 mg/KgBB), how to calculate Indonesian Pharmacopoeia (187,068 mg/KgBB). Based on the three calculations, the LD50 value is in the medium category (50-500 mg/kgBB).
Pelatihan Pengelolaan Sampah, Pembuatan Dekomposer dan Pupuk Organik Cair bagi Santri Panti Asuhan Ruhamaa Kota Samarinda Djihan Ryn Pratiwi; erwin erwin; Ika Yekti liana Sari; irfa Ashari Hyahara; Noor Hindryawati; Eva Marliana
Jurnal Abdimas Mahakam Vol. 7 No. 01 (2023): Abdimas Mahakam
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24903/jam.v7i01.1977

Abstract

Panti asuhan adalah suatu lembaga pelayanan sosial yang didirikan oleh pemerintah maupun masyarakat, bertujuan untuk membantu individu, kelompok masyarakat. Salah satu panti asuhan yang ada di kota Samarinda adalah Panti Asuhan Ruhama yang beralamatkan di Jalan Suryanata Kelurahan Bukit Pinang. Panti Asuhan Ruhama memenuhi kebutuhan anak-anak yang dirawatnya mulai dari tempat tinggal, makanan, kebutuhan sehari - hari hingga sekolahnya. Dalam Kegiatan sehari - hari Panti Asuhan Ruhama banyak menghasilkan sampah, sampah dipanti asuhan Ruhamaa terutama sampah organik belum dimanfaatkan dengan baik padahal panti Asuhan Ruhama memiliki green house. Untuk itu Dosen Jurusan Kimia FMIPA UNMUL bekerjasama dengan PT. Global Environmet Laboratory (PT. GEL) pada hari Minggu, 25 September 2022 memberikan pelatihan mengenai Pengelolaan Sampah, Pembuatan Dekomposer dan Pupuk Organik Cair (POC) dari sampah organik berupa nasi sisa Bagi Santri Panti Asuhan Ruhama Kota Samarinda. Metode pengabdian masyarakat yang dilakukan adalah metode ceramah ; memberikan materi pengelolaan sampah dan pembuatan dekomposer dan pupuk organik cair, metode eksperimen ; santri panti asuhan ruhama praktek terkait materi yang sudah disampaikan sebelumnya dan mengaplikasikan langsung pupuk organik cair yang sudah dibuat ke tanaman yang ada di green house milik panti. Dengan metode ceramah dan eksperimen dapat menambah pengetahuan dan skill keterampilan santri dalam mengelola sampah, pembuatan dekomposer dan pupuk organik cair (POC) serta dapat mengaplikasikan langsung di green house milik panti. Dari hasil kuisioner dapat dijabarkan bahwa santri Panti Asuhan Ruhamaa menanggapi baik dengan rata - rata tanggapan terhadap pernyataan yang diberikan adalah baik sekali dengan presentase untuk tiap pernyataan sebesar 90%.
The larvicidal activity of auraptene: oxygeranylated coumarin from Limonia acidissima L. Siti Mariyatul Ulfah; Tjitjik Srie Tjahjandarie; Mulyadi Tanjung; Ratih Dewi Saputri; Eva Marliana
Acta Chimica Asiana Vol. 9 No. 1 (2026)
Publisher : The Indonesian Chemical Society, Chapter Nusa Tenggara and The University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/aca.v9i1.288

Abstract

Limonia acidissima  L. (Rutaceae) is a plant rich in coumarin compounds and has been used in traditional medicine. One of the main coumarin compounds reported from the roots of this plant is auraptene (7-oxygeranylcoumarin), which has previously been reported to have antioxidant activity. With increasing cases of vector-borne diseases, especially dengue fever transmitted by Aedes aegypti, the development of effective and environmentally friendly natural larvicides is needed. This study aimed to evaluate the larvicide activity of auraptene, building on previous research. The larvicide test was carried out using the WHO larval bioassay method on third-instar A. aegypti larvae at concentrations of 25–500 ppm within an exposure time of 24 h. Mortality data were analyzed using probit analysis to determine the Lethal Concentration 50% (LC50) value. The results showed that auraptene increased larval mortality with an LC50 of 145.29 ± 0.02 ppm after 24 h of exposure. This value indicates that auraptene is classified as an active natural larvicide. In conclusion, auraptene has the potential to be developed as a natural larvicidal candidate against A. aegypti and may expand the spectrum of biological activity of coumarin compounds from L. acidissima L.
AKTIVITAS ENZIM LIPASE PADA BERBAGAI KECAMBAH BIJI TUMBUHAN: A MINI REVIEW Mita Haryani; Djihan Ryn Pratiwi; Eva Marliana
PROSIDING SEMINAR KIMIA Vol 4 No 2 (2025): Prosiding SNKT 2025
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Lipase is an enzyme that functions as a catalyst in the hydrolysis reaction of triglycerides into glycerol and free fatty acids. Lipase has wide applications in various fields such as the food industry, cosmetics, biotechnology, and biocatalysis. This review examines the activity of lipase enzymes derived from various tropical plant sources based on previous research results using in vitro enzymatic assay methods. Lipase activity was detected in germinated seed samples of several plant species, including Jackfruit Seed Sprouts (Artocarpus integer), Avocado Seed Sprouts (Persea americana Mill), Cocoa Seeds (Theobroma cacao L.), Indian Almond Seed Sprouts (Terminalia catappa L.), Rambutan Seed Sprouts (Nephelium lappaceum L.), Durian Seed Sprouts (Durio zibethinus R.), Kesambi Seed Sprouts (Schleichera oleosa L.), Sunflower Seeds (Helianthus annuus L.), Jatropha Seed Sprouts (Jatropha curcas L.), and Palm Princess (Veitchia merrillii). The results showed varying lipase activity values ranging from 0.100 to 41.5 U/mL, reflecting differences in expression and physiological function. The highest lipase activity was found in Kesambi Seed Sprouts (Schleichera oleosa L.) with a value of 41.5 U/mL, while the lowest was found in Cocoa Seeds (Theobroma cacao L.) with a value of 0.010 U/mL. These findings indicate that Kesambi Seed Sprouts have strong potential to be further developed as a source of lipase enzymes for various industrial and biotechnological applications. Keyword: Plants, Enzymes, Lipase, lipase enzyme activity
Co-Authors -, Nurfadzillah Afandi, Irvan Agustina R. M. Alma Yulvita Pebriana Amalia, Elfiza Aman S. Panggabean Anggriani, Yusnia Wati Aryoga Oktabriangga Saputra Audia, Nuraini Meti Ayu Mellyanti Az-zahra, Deannisa Khoiru Chairul salaeh Daniel Daniel -, Daniel Daniel Daniel Daniel Daniel Daniel Daniel Daniel Daniel Dewi, Dynda Rosiana Djihan Ryn Pratiwi Djihan Ryn Pratiwi, Djihan Ryn Doni Prio Atmoko Dwi Lestari Ersa Marina Rahmawati Erwin Erwin Erwin Erwin Erwin Erwin Erwin Erwin Fikriah, Ika Firmansyah, Muchammad Ravi Husnul Chatimah Ika Yekti Liana Sari Indra Masmur irfa Ashari Hyahara Isyahro, Novia Rahmawati Jumaidil Awal K Y Margiati, K Y Kim, Soo-Ya Kim, Yong-ung Kusuma, Irawan W. Madaniah Fathirah Magdaleni, Agustina Rahayu Masmur, Hestina Masruhin, Muhammad A. Medi Hendra Mikdariawan, Adha Mita Haryani Muh. Naufal Hisyam Muhammad Marion Akbar Mulyadi Tanjung Mulyana Mulyana Nabila, Sahira Fara Nanang Tri Widodo Nanang Tri Widodo Nanang Tri Widodo Nisa, Nahdia Khairun Noor Hindryawati Noor Hindryawati, Noor Novia Rahmawati Isyahro Novia Rahmawati Isyahro Nur Aina Nur Hidayah Nur Khasanah Nur Khsanah Nurul Jannah Pramana, Aditiya Hadi Ryan Purnamasari, Ade Rezki Rachman, Ferry Aditya Rahimah, Priliza Rahmat Gunawan Rakasiwi, Dea Ramadhani, Riski Vebryanti Ratih Dewi Saputri Ratna Kusuma Rismawati Rismawati Rita Hairani Ritbey Ruga Ritson Purba, Ritson Rudi Kartika, Rudi Ruga, Ritbey Saibun Sitorus Saleh, Chairul Siti Halidjah Siti Mariyatul Ulfah Siti Nurjanah Soerja Koesnarpadi Subur P Pasaribu Swandari Paramita Syamsul Arifin Teguh Wirawan, Teguh Tjitjik Sri Tjahjandarie Tjitjik Srie Tjahjandarie Tullah, Mirna Hidaya Winni Astuti Winni Astuti, Winni