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All Journal Journal of Tropical Life Science : International Journal of Theoretical, Experimental, and Applied Life Sciences Dentino: Jurnal Kedokteran Gigi Berkala Kedokteran Acta Biochimica Indonesiana Homeostasis: Jurnal Mahasiswa Pendidikan Dokter Jurnal Abdimas Mahakam
Dona Marisa, Dona
Departemen Biomedik Divisi Fisiologi Fakultas Kedokteran Universitas Lambung Mangkurat, Banjarmasin
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Public Health Other

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Anti-Lipid Peroxidation Activities of Three Selected Fruits Juices Against Cadmium Induced Liver Damage In Vitro Eko Suhartono; June Astri Nijka; Vini Yulia Anhar; Rizki Amalia Sari; Edyson Edyson; Dona Marisa
Journal of Tropical Life Science Vol. 5 No. 2 (2015)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.05.02.03

Abstract

Cadmium (Cd) is one of the most toxic heavy metal. Numerous tissues both in vitro and in vivo suggest that Cd induced lipid peroxidation. The presence of antioxidant can inhbit this process. This present study was designed to determine the effects of mango, papaya, and banana juices on on malondi aldehyde levels (MDA, product of cellular lipid peroxidation) during Cd exposure in vitro. Significant differences was observed between three selected fruits juices and MDA levels and also between concentration of fruits juices and MDA levels. The highest correlation was found between banana juices and MDA levels with IC50 1,12, and followed by papaya and mango juices with IC 50 1,37 and 3,87 respectively. The findings of this study suggest that the three selected fruits juices may exert its protective action against Cd-induced lipid peroxidation in liver homogenate in vitro possibly through its antioxidant mechanism.Key WordCadmium, Lipid Peroxidation, Antioxidant Activity and Fruits Juices
HUBUNGAN TEKANAN DARAH DENGAN FUNGSI KOGNITIF PADA GERIATRI DI RSUD ULIN BANJARMASIN Diva Aurellia Rosa; Pagan Pambudi; Ahmad Husairi; Muhammad Welly Dafif; Dona Marisa
Homeostasis Vol 5, No 3 (2022)
Publisher : Homeostasis

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Abstract

One health problems that often occur in elderly is a decline in cognitive function. The brain needs oxygen and glucose reserves to work, if there is a blood vessel blockage, it can cause oxygen and glucose inadequacy which can reduce the work function of brain nerve cells. Hypertension is a medical condition of an elevated vascular blood pressure above normal limits. The purpose of this study was to analyze the relationship between blood pressure and cognitive function in the elderly at RSUD Ulin Banjarmasin. This study is an analytic observational study using a cross-sectional method with total of 32 elderly people were selected using a purposive sampling method. Data was analyzed by using Pearson. The average value systolic blood pressure was 152,2 ± 5,1 from secondary data of medical record, and the average value of cognitive function using the Mini Mental State Examination (MMSE) was 26,3 ± 1,0 with Pearson correlation test results obtained value of p = 0.594 and r = 0.098. These findings provide additional evidence that there is no relation between blood systolic pressure and cognitive function in the elderly in RSUD Ulin Banjarmasin
LITERATURE REVIEW: KOMPONEN NYERI NEUROPATIK PADA NYERI PUNGGUNG BAWAH Nasywa Maharani Yudiantara; Pagan Pambudi; Ahmad Husairi; Muhammad Welly Dafif; Dona Marisa
Homeostasis Vol 5, No 3 (2022)
Publisher : Homeostasis

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Abstract

Low back pain is a very common health problem and can affect the quality of life. Pain that arises in low back pain can be either nociceptive pain or neuropathic pain. This literature review discusses the neuropathic pain component of low back pain.  This review uses a narrative review method. The articles were obtained from keyword searches in the Science Direct, PubMed, and ProQuest databases with a publication range of 2011-2021 in Indonesian or English, and research on the components of neuropathic pain in low back pain. Of the eight articles included in this literature review, the prevalence of neuropathic pain in low back pain was 2.8% - 65.3%. Neuropathic pain can be ruled out using LANSS, DN4, and PDQ. Low back pain with neuropathic pain had symptoms of burning (34.58% - 82.9%), pinpricks (31.77% - 78%), tingling (32.71% - 84.8%), numbness (42.05% - 97%), electric shock (38.97% - 78%), itching (16.82% - 42.4%), cold sensation (12.15% - 48.5%), allodynia (19.62% - 85.4%), 61% hyperalgesia, 14.6% autonomic dysfunction, 100% had dysesthesia, and 100% experienced a decrease in tenderness/prickling. Radicular low back pain is often caused by L5 or S1 root compression and rarely L4. Neuropathic low back pain can be based on an assessment of the symptom profile. Associated risk factors are older age, being a female, greater anthropometric status, the habit of drinking alcohol, smoking, and history of previous lumbar, abdominal or pelvic surgery
PERBEDAAN WAKTU REAKSI SEBELUM DAN SESUDAH LARI AEROBIK 12 MENIT PADA REMAJA TERLATIH BASKET DAN TIDAK Muhammad Hasan Ridhoni; Siti Kaidah; DOna Marisa; Asnawati Asnawati; Didik Dwi Sanyoto; Muhammad Marwan; Finna Rahmiati
Homeostasis Vol 6, No 1 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i1.8811

Abstract

Pada masa pandemi Covid 19, latihan fisik atau olahraga merupa hal yang penting untuk dilakukan guna meningkatkan kesehatan dan kebugaran tubuh. Lari aerobik 12 menit dengan intensistas sedang merupakan salah satu jenis latihan fisik yang biasa dilakukan oleh semua golongan umur terutama  remaja. Latihan fisik sangat berhubungan erat dengan waktu reaksi. Waktu reaksi adalah seberapa cepat seseorang merespon terhadap suatu stimulus/rangsangan. Penelitian ini bertujuan untuk menjelaskan perbedaan waktu reaksi sebelum dan sesudah lari aerobik 12 menit dengan intensitas sedang pada remaja terlatih basket dan tidak terlatih basket. Penelitian dilakukan dengan Cross Sectional Study pada 15 siswa pemain basket dan 15 siswa bukan pemain basket SMAN 1 Banjarbaru. Teknik pengambilan sampel dilakukan dengan metode purposive sampling. Analisis data menggunakan T-test berpasangan (sebelum dan sesudah) dan T-test tidak berpasangan (terlatih dan tidak terlatih) dan uji mann-whitney (selisih waktu reaksi). Hasil analisis data adalah terdapat perbedaan bermakna (p=0.000) antara nilai waktu reaksi  remaja terlatih basket (0,020) dan remaja tidak terlatih basket (0,040). Hasil penelitian ini menyimpulkan bahwa waktu reaksi remaja terlatih basket lebih baik dibanding remaja tidak terlatih basket dilihat dari hasil selisih waktu reaksi sebelum dan sesudah lari aerobik 12 menit dengan intensitas sedang
HUBUNGAN ANTARA USIA DAN JENIS KELAMIN DENGAN KEJADIAN STROKE PADA PASIEN DIABETES MELITUS DI RSUD ULIN BANJARMASIN Theresa Tyra Sertani; Nanang Miftah Fajari; Mohammad Bakhriansyah; Wiwit Agung Sri Nur Cahyawati; Dona Marisa
Homeostasis Vol 6, No 1 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i1.8802

Abstract

Diabetes melitus (DM) merupakan penyakit kronis yang ditandai dengan terjadinya peningkatan kadar glukosa darah melebihi normal atau hiperglikemia, salah satu penyakit kardiovaskuler yang berisiko besar terjadi pada penderita DM adalah stroke. Usia dan jenis kelamin merupakan faktor yang diduga berpengaruh terhadap terjadinya risiko stroke pada pasien DM. Tujuan penelitian ini untuk mengetahui hubungan antara usia dan jenis kelamin dengan kejadian stroke pada pasien DM. Penelitian observasional analitik ini menggunakan pendekatan potong lintang pada 108 pasien yang tercatat di pangkalan data milik Poliklinik Endokrin RSUD Ulin Banjarmasin yaitu BEST DIAB 2 (Borneo Wetland Study on Diabetes 2). Pengambilan sampel secara total sampling untuk pasien stroke dan simple random sampling untuk pasien tidak stroke dengan perbandingan 1:1. Data dianalisis dengan uji Fisher’s exact dan Chi-square menggunakan perangkat lunak statistik SPSS versi 26. Penelitian ini menunjukkan tidak ada hubungan antara usia (p=0,205) dan jenis kelamin (p=1,00) terhadap kejadian stroke pada pasien DM di RSUD Ulin Banjarmasin.
HUBUNGAN ANTARA INDEKS MASSA TUBUH DENGAN KEJADIAN STROKE PADA PASIEN DIABETES MELITUS DI RSUD ULIN BANJARMASIN Widi Aurelia Mirmaningtyas; Nanang Miftah Fajari; Mohammad Bakhriansyah; Wiwit Agung Sri Nur Cahyawati; Dona Marisa
Homeostasis Vol 6, No 2 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i2.10016

Abstract

Diabetes melitus (DM) merupakan penyakit metabolik yang dapat mengakibatkan beberapa komplikasi salah satunya berupa stroke. Indeks massa tubuh (IMT) diduga dapat meningkatkan risiko terjadinya stroke pada pasien DM. Tujuan penelitian ini adalah untuk mengetahui hubungan antara IMT dengan kejadian stroke pada pasien DM. Penelitian ini bersifat observasional analitik dengan pendekatan potong lintang pada 52 data pasien stroke yang dipilih menggunakan metode total sampling dan 52 data pasien tidak stroke yang dipilih menggunakan metode simple random sampling. Data pasien diperoleh dari pangkalan data Borneo Wetland Study on Diabetes 2 (BEST-DIAB 2) milik Poliklinik Endokrin RSUD Ulin Banjarmasin. Data dianalisis menggunakan uji Chi-square dengan perangkat lunak SPSS versi 26. Hasil analisis menunjukan bahwa tidak terdapat hubungan yang bermakna secara statistik antara IMT dengan kejadian stroke pada pasien DM di RSUD Ulin Banjarmasin (p=0,377).
HUBUNGAN INDEKS MASSA TUBUH DENGAN SIKLUS MENSTRUASI PADA MAHASISWA PSKPS ULM ANGKATAN 2019-2021 Cibro, Impana; Kaidah, Siti; Marisa, Dona; Asnawati, Asnawati; Sanyoto, Didik Dwi
Homeostasis Vol 6, No 3 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i3.11452

Abstract

The menstrual cycle is the distance from the first day of menstruation in one month to the following month. This is influenced by several things, one of which is the body mass index. This study aims to explain the relationship between body mass index and the menstrual cycle in PSKPS ULM student class of 2019-2021. This research was carried out using the analytic observational method with a cross-sectional approach on 113 PSKPS ULM student class of 2019-2021. The sampling technique was carried out using the total sampling method where all respondents who met the inclusion criteria were used as research subjects. Subjects were asked to fill out a research questionnaire online via the Google form. 70 people (61.9%) had normal BMI, 43 people (38.1%) had abnormal BMI, 92 people (81.4%) had regular menstrual cycles and 21 people (18.6%) irregular. Of the 70 people with normal BMI, 59 people had regular menstrual cycles, and 11 people had irregular cycles. Of the 43 people with abnormal BMI, 32 people had regular menstrual cycles, and 10 people had irregular menstrual cycles. Data analysis used the chi square statistical test. The results of the data analysis showed that there was no relationship between body mass index and the menstrual cycle in PSKPS ULM student class of 2019-2021 (p=0.272).
KORELASI KADAR MASSA OTOT DAN KUALITAS HIDUP PADA PASIEN YANG MENJALANI HEMODIALISIS RUTIN DI RSUD ULIN BANJARMASIN Ariewardana, Angger; Rudiansyah, Mohammad; Pratiwi, Dewi Indah Noviana; Cahyawati, Wiwit Agung Sri Nur; Marisa, Dona
Homeostasis Vol 7, No 2 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i2.13180

Abstract

Abstract: Chronic Kidney Disease (CKD) is defined as kidney damage or a decrease in the gromerular filtration rate that occurs for 3 months or more, manifesting as kidney damage and requiring kidney replacement therapy, namely hemodialysis. CKD sufferers often experience an energy imbalance due to anorexia which increases energy needs while energy reserves are depleted. Muscle mass levels function as bone moving organs. Muscle mass will be measured using the BIA (Bioimpedance Analysis). Low muscle mass is often associated with low quality of life. Quality of life is an assessment of several aspects of life. Hemodialysis therapy will affect quality of life including lack of energy, fatigue and stress. Quality of life can be measured using the SF-36 questionnaire. This study was to regulate the correlation among muscle mass levels and the level of quality of life of routine hemodialysis patients at RSUD Ulin Banjarmasin. The research method uses analytical observational with a cross-sectional approach. The technique for taking subjects was simple random sampling of 60 subjects. Data collection was carried out by direct measurements and interviews of muscle mass levels and quality of life. Data analysis used the Komolgorov-Smirnov normality test and continued with test called Pearson correlation test. The results of data analysis showed a strong significant correlation (p=0.000, r=0.706). The results of the study concluded that muscle mass levels had a significant correlation with the level of quality of life of hemodialysis patients at RSUD Ulin Banjarmasin. Keywords: Muscle mass, quality of life, hemodialysis, BIA (Bioimpedance analysis), questionnaire QOL Short Form-36. Abstrak: Penyakit ginjal kronis (PGK) didefinisikan sebagai kerusakan ginjal atau penurunan laju filtrasi gromerulus yang terjadi selama 3 bulan atau lebih bermanifestasi sebagai kerusakan ginjal dan memerlukan terapi pengganti ginjal yaitu hemodialisis. Penderita PGK sering mengalami ketidakseimbangan energi akibat anoreksia yang meningkatkan kebutuhan energi sementara asupan energi cadangan habis. Kadar massa otot berfungsi sebagai organ penggerak tulang. Massa otot dapat diukur salah satunya dengan menggunakan alat BIA (Bioimpedance analysis). Rendahnya massa otot kerap dihubungkan dengan rendahnya kualitas hidup. Kualitas hidup merupakan penilaian beberapa aspek dalam kehidupan. Terapi hemodialisis akan mempengaruhi kualitas hidup meliputi kekurangan energi, kelelahan, dan stress. Kualitas hidup dapat diukur salah satunya menggunakan kuesioner SF-36. Tujuan penelitian ini adalah untuk mengetahui korelasi kadar massa otot dan kualitas hidup pasien hemodialisis rutin di RSUD Ulin Banjarmasin. Metode penelitian menggunakan observasional analitik dengan pendekatan cross-sectional. Teknik pengambilan subjek dengan simple random sampling sebanyak 60 subjek. Pengambilan data dilakukan dengan pengukuran dan wawancara langsung kadar massa otot dan kualitas hidup. Analisis data menggunakan uji normalitas Komolgorov-Smirnov dan dilanjutkan dengan uji korelasi Pearson. Hasil analisis data terdapat korelasi bermakna kuat (p=0,000, r=0,706). Hasil penelitian menyimpulkan kadar massa otot terdapat korelasi bermakna dengan kualitas hidup pasien hemodialis di RSUD Ulin Banjarmasin. Kata-kata kunci: Massa otot, kualitas hidup, hemodialisis, BIA (bioimpedance analysis), kuesioner QOL Short form-36.
HUBUNGAN ANTARA LAMA MENDERITA DIABETES MELITUS DENGAN KEJADIAN STROKE DI RSUD ULIN BANJARMASIN Munirah, Nida; Fajari, Nanang Miftah; Bakhriansyah, Mohammad; Cahyawati, Wiwit Agung Sri Nur; Marisa, Dona
Homeostasis Vol 6, No 3 (2023)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v6i3.11463

Abstract

Diabetes mellitus (DM) is a metabolic disorder that if it is left untreated for a long period could lead to various complications such as stroke. The longer duration of DM is predicted to increase the risk of stroke. The purpose of this study was to determine the relationship between the duration of DM with the risk of stroke. This was an analytic observational study with a cross-sectional approach. This study involved 54 DM patients with stroke selected by using total random sampling method and 54 DM patients without stroke selected by using simple random sampling method. Data were obtained from the Borneo Wetland Study on Diabetes 2 (BEST-DIAB 2) database owned by Poliklinik Endokrin RSUD Ulin Banjarmasin. Data were then analyzed by using Chi-square test in a statistical software the SPSS version 26 with 95% of confidence interval.  The results showed that no significant relationship (p=0.501) between the duration of DM with the risk of stroke for patients with DM at RSUD Ulin Banjarmasin.  
KORELASI TEBAL LEMAK BAWAH KULIT DENGAN NILAI FVC PADA MAHASISWA PSKPS FK ULM Azzahra, Wikha; Kaidah, Siti; Marisa, Dona; Asnawati, Asnawati; Haryati, Haryati
Homeostasis Vol 7, No 1 (2024)
Publisher : Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/ht.v7i1.12409

Abstract

Abstract: Body fat measurement can be performed in various ways, one of which is by measuring skinfold thickness. Excess body fat is often associated with decreased lung function. Spirometry, a crucial screening method, assesses respiratory health by measuring inspiratory and expiratory air volume. This study aimed to determine the correlation between skinfold thickness and FVC value of medical students at Lambung Mangkurat University. The research utilized an observational analytical method with a cross-sectional approach, sampling 32 participants through simple random sampling. Data collection involved direct measurement of skinfold thickness and the FVC value. Data was analyzed with the Pearson correlation test. The results revealed no significant correlation (p=0.472, r=-0.132) between skinfold thickness and the FVC value of medical students at Lambung Mangkurat University. In conclusion, skinfold thickness showed no significant correlation with the FVC value of medical students at Lambung mangkurat University Keywords: fat mass, skinfold thickness, FVC value, spirometry Abstrak: Banyak cara yang dapat dilakukan untuk mengukur massa lemak tubuh, salah satu caranya adalah dengan mengukur tebal lipatan kulit dan diukur pada area spesifik sesuai standar. Massa lemak yang berlebihan dalam tubuh erat dihubungkan dengan penurunan fungsi paru. Pemeriksaan spirometri merupakan metode screening yang sangat penting dilakukan untuk menilai kesehatan pernapasan secara umum dengan cara melihat nilai volume udara inspirasi dan ekspirasi. Tujuan dari penelitian ini adalah untuk mengetahui korelasi antara tebal lemak bawah kulit dengan nilai FVC pada mahasiswa PSKPS FK ULM. Metode penelitian bersifat observasional analitik dengan pendekatan cross-sectional. Pengambilan sampel dilakukan menggunakan teknik simple random sampling sebanyak 32 partisipan. Analisis data dilakukan dengan menggunakan uji korelasi Pearson. Hasil analisis data penelitian ini yaitu tidak terdapat korelasi bermakna (p=0,472, r=-0,132). Hasil penelitian ini menyimpulkan bahwa tebal lemak bawah kulit tidak memiliki korelasi bermakna dengan nilai FVC pada mahasiswa PSKPS FK ULM. Kata-kata kunci: lemak tubuh, tebal lemak bawah kulit, nilai FVC, spirometri
Co-Authors Abdian Purnapita Pambudi Achmad Rofii Ahmad Husairi Ahmad Husairi Ahmad Husairi Ajeng Dwi Novitasari Alfi Yasmina Anggia Ayunanda Arrafieka Annisa Susilo Anwari Delmi Ariewardana, Angger Asnawati Asnawati Asnawati Asnawati Asnawati Asnawati Athiya Nadifa Azzahra, Wikha Bagus Maulana Akbar Cibro, Impana Dewi Indah Noviana Pratiwi, Dewi Indah Noviana Diah Mutia Rahmawati Didik Dwi Sanyoto Diva Aurellia Rosa Dohamid, Firdinia Gafuri Dwi Laksono Adiputro Dwi Laksono Adiputro Dwi Laksono Adiputro Dwi Laksono Adiputro Edi Hartoyo Edyson Edyson Effiyana, Arika Eka Dewi Yanti Eko Suhartono Fakhrurrazy Fakhrurrazy Farisa Shauma Fachir Farisa Shauma Fachir, Farisa Shauma Farizka Erianti Farizka Erianti, Farizka Fauzan Muttaqien Fauzan Muttaqien Fauzan Muttaqien Febryan, Marcellino Finna Rahmiati Firdaus, Muhammad Reyhan Firdinia Gafuri Dohamid Firman Raudana Gusti Muhamma Edy Muttaqin Gusti Muhamma Edy Muttaqin, Gusti Muhamma Edy Handono Kalim Haryati Haryati Hasna, Usratul Hayati, Azka Huldani Huldani Irham Taufiqurrahman Iskandar Iskandar Islami, Shafira Aulia Istiana Istiana Ivana Ellenora Ellenora June Astri Nijka Khan, Muhammad Fawwaz Kusworini Handono Lisda Hayatie, Lisda M Naufal Firdaus M. Iqbal Hisyam Qiroth Mashuri Mashuri Mohammad Bakhriansyah Mohammad Bakhriansyah Mohammad Rudiansyah Muhammad Farid Adlirrahman Muhammad Hasan Ridhoni Muhammad Marwan Muhammad Muzain Azhar Muhammad Welly Dafif Muhammad Welly Dafif Munirah, Nida Muthaminah, Noor Muthmainah, Noor Nanang Miftah Fajari Nasywa Maharani Yudiantara Noer Komari Noor Muthaminah Nur Qamariah Oski Illiandri Oski Illiandri Pagan Pambudi Panghiyangani, Roselina Perdana Putera, Gusti Muhammad Pradito, Syaifullah Akbar Prenggono, Muhamad Darwin Putri Nur Aini Rafida Ikhsania Camalis Ramadan, Yoga Aditya Noor Rizki Amalia Sari Rizky Frida Monica Santrino, Syifa Nurafifah Sanyoto, Didik Dwi Septiyan Dimas Putra Akbar Sherly Limantara Sherly Limantara Siddik, Muhammad Siti Juliati Siti Kaidah Theresa Tyra Sertani Vini Yulia Anhar Vivin Nurul Islami Widi Aurelia Mirmaningtyas Wiwit Agung Sri Nur Cahyawati Yusril Gunawan Zairin Noor Zulfikar, Muhammad Rakha