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All Journal JURNAL ANATOMI FISIOLOGI VISIKES Indonesian Journal of Natural Pigments JKPK (Jurnal Kimia dan Pendidikan Kimia) Jurnal Ilmiah Kesehatan Ar-Rum Salatiga Jurnal Ilmiah Cendekia Eksakta Jurnal DiMas (Jurnal Pengabdian Kepada Masyarakat) Media Farmasi Indonesia Molekul: Jurnal Ilmiah Kimia Journal of Tropical Pharmacy and Chemistry Berita Biologi

Ahmad Fuad Masduqi

STIFAR Yayasan Pharmasi Semarang

Author-ID : 317218

Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Health Professions Immunology & microbiology Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Veterinary Other

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Efek Metode Pengeringan Terhadap Kandungan Bahan Kimia Dalam Rumput Laut Sargassumpolycystum Masduqi, Ahmad Fuad; Izzati, Munifatul; Prihastanti, Erma
BULETIN ANATOMI DAN FISIOLOGI dh SELLULA Vol 22, No 1 (2014): Volume XXII, NOMOR 1, MARET 2014
Publisher : BULETIN ANATOMI DAN FISIOLOGI dh SELLULA

Sargassum polycystum as a seaweed that contains several chemical. Chemical in Sargassum polycystum is potential to be exploited and developed. Post harvest handling of Sargassum polycystum is very important, especially in drying method. Drying method will affect the chemical contentin Sargassum polycystum. The aims of this research is to study the effect of drying methods to the chemical in Sargassum polycystum. This research is conducted in the Biology laboratory, department of Biology faculty of Sains and Mathematics Diponegoro University. This research was designed by random complete design. The research was the methods of drying (under the sun, using the oven and wind drying), each treatment were replicated 3 times. The resulted data was analized by Analysis of Variance (ANOVA) continued by real difference test Duncan Multiple Range Test (DMRT) in 95% significance level. The parameters in this research were the content of total phenols, alginate, proximate (ash content, water, fat, crude protein and crude fiber). Beside that, the effectivity of Sargassum polycystum flour for fish presertative were also examined by calcuting the number of bacteria and organoleptic parameters, including the freshness, durability and fish performance. The result showed that drying methods affect the content of total phenols, alginate and proximate of Sargassum polycystum. Wind drying method is the most efficient drying in getting the phenolic compounds (at 1656.3ppm).

Pengaruh Penambahan Pembenah Tanah Dari Pistia stratiotes L. dan Ceratophyllum demersum L. Pada Tanah Pasir dan Liat Terhadap Kapasitas Lapang dan Pertumbuhan Kacang Hijau (Vigna radiata L.) Masduqi, Ahmad Fuad; Izzati, Munifatul; Saptiningsih, Endang
BULETIN ANATOMI DAN FISIOLOGI dh SELLULA Vol 12, No 1 (2012): VOL XX, NOMOR 1, TAHUN 2012
Publisher : BULETIN ANATOMI DAN FISIOLOGI dh SELLULA

Bahan pembenah tanah (soil conditioner) adalah material-material yang ditambahkan kedalam tanah. Pembenah tanah mampu memperbaiki struktur tanah, mengubah kapasitas tanah menahan dan melalukan air, sehingga dapat mendukung pertumbuhan tanaman. Penambahan pembenah tanah dapat meningkatkan kapasitas lapang dan pertumbuhan tanaman kacang hijau. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan pembenah tanah terhadap kapasitas lapang dan pertumbuhan kacang hijau pada tanah pasir dan liat. Penelitian ini dilaksanakan di Laboratorium Biologi Struktur dan Fungsi Tumbuhan Jurusan Biologi FMIPA Undip dan rumah kaca Jurusan Biologi FMIPA Undip. Rancangan yang digunakan adalah rancangan acak lengkap pola faktorial dengan 3 pengulangan. Faktor pertama yaitu tekstur tanah (pasir dan liat). Faktor kedua adalah pembenah tanah (kontrol, Pistia dan Ceratophyllum). Hasilnya menunjukkan bahwa penambahan pembenah tanah dari P.stratiotes dan C.demersum meningkatkan kapasitas lapang pada tanah pasir dan liat. Penambahan pembenah tanah dari P.stratiotes dan C.demersum juga meningkatkan tinggi tanaman, jumlah daun, berat basah dan berat kering tanaman kacang hijau pada tanah pasir dan liat. Berdasarkan hasil uji DMRT tarafÂ signifikasi 95% penambahan pembenah tanah berpengaruh terhadap kapasitas lapang tanah pasir dan liat, tinggi tanaman, jumlah daun, berat basah dan berat kering tanaman kacang hijau

Activity Antioxidant on Pigments of Bacterial Symbionts of Soft Coral From Jepara Sea Masduqi, Ahmad Fuad; Franyoto, Yuvianto Dwi; Kusmita, Lia; Muchlisin, Sakti; Widyananto, Prasetyo Abi; Sulistyani, Sulistyani; Wijayanti, Diah Permata
Indonesian Journal of Natural Pigments Vol 2 No 2 (2020): Agustus 2020
Publisher : Ma Chung Research Center for Photosynthetic Pigments

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33479/ijnp.2020.02.02.43

Soft corals have been known to produce secondary metabolites, some of which may have anticancer, antifouling, antibacterial and antioxidants activity. It has been suggested that natural products from marine invertebrates have striking similarities to metabolites of their association microorganisms. Symbiont bacteria on soft coral can produce bioactive compounds that play an important role in chemical ecology and as a marine natural product. Marine bacteria associated with soft coral collected from Jepara were successfully isolated on medium ZoBell 2216E and screened to synthesize the pigment. This approach has allowed the use of this organism as an environmentally friendly alternative source of new natural pigment. This study found 25 bacterial isolates from 6 types of soft coral. Out of 25 bacterial isolates, only 3 bacterium, positively contains pigments. Four isolates, PCl 1, PS2 1, and PSa 2. Pigments analysis with UV spectrophotometric method showed the wavelength of pigments were in the range 300-600 nm. Genomic DNA was isolated from these colonies and nested PCR of the DNA was performed to amplify the 16S rDNA. Antioxidant activity was tested with the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. From the results of molecular identification by 16S rDNA method, it was shown that bacterium PCl 1, PS2 1, and PSa 2 was closely related to Pseudomonas stutzeri, Ponticoccus gilvus, Bacillus marisflavi with 99%, 99and 98% homology value. Antioxidant activity is as follows: PCl 1>PS2 1>PSA 2.

UJI AKTIVITAS ANTIBAKTERI MASKER GEL PEEL OFF EKSTRAK DAUN PLETEKAN (Ruellia tuberosa L.) TERHADAP Staphylococcus aureus Mighfar Syukur; Ahmad Fuad Masduqi
VISIKES: Jurnal Kesehatan Masyarakat Vol 21, No 1 (2022): VISIKES
Publisher : Dian Nuswantoro Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33633/visikes.v21i1Supp.5962

Staphylococcus aureus is one of the pathogenic bacterial species. Pletekan plant has potential as a medicinal plant. This plant contains secondary metabolites and has been shown to have an antibacterial effect. The purpose of this study was to determine whether the peel off gel mask pletekan leaf extract could inhibit the growth of Staphylococcus aureus and whether there was a difference in the antibacterial activity of the peel off gel mask pletekan leaf extract at concentrations of 20%, 25%, and 30%. This research used maceration extraction method, phytochemical filtering and TLC. Peel off gel mask formulation from extracts with different concentrations. Furthermore, the research was carried out to test the antibacterial activity by using the well-drilled method on the peel off gel mask of pletekan leaf extract (Ruellia tuberosa L.) against the growth of Staphylococcus aureus. The results of screening and TLC showed pletekan leaf extract containing flavonoids, steroids, triterpenoids, and alkaloids. The peel off gel mask preparation test includes organoleptic, pH, homogeneity, adhesion, dispersion and drying time included in the Indonesian National Standard Criteria. The results showed that pletekan leaf extract (Ruellia tuberosa L.) in a peel off gel mask could inhibit the growth of Staphylococcus aureus. The results of statistical tests showed that the data were normally distributed and homogeneous. There was a significant difference in antibacterial activity in the peel off gel mask of pletekan leaf extract with concentrations of 20%, 25% and 30%, which were 4.323mm; 5.218mm; and 6.509mm. The antibacterial activity showed that the concentration was directly proportional to the resulting inhibition zone.

Synthesis of Core-Shell Fe3O4/C18/SiO2/[3 (2-Aminoethyl amino) propyl] Trimethoxy Silane and The Study of The Adsorption Kinetics Model of Cu2+ and Cr6+ Ions Mighfar Syukur; Ahmad Fuad Masduqi
JKPK (Jurnal Kimia dan Pendidikan Kimia) Vol 5, No 2 (2020): JKPK (Jurnal Kimia dan Pendidikan Kimia)
Publisher : Program Studi Pendidikan Kimia FKIP Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jkpk.v5i2.37820

Synthesis of Core-Shell Fe3O4/C18/SiO2/[3 (2-Aminoetil amino) propyl] Trimethoxy silane has been conducted to study its adsorption kinetics of Cu2+ and Cr6+ ions. Fe3O4 synthesis was carried out to form cores that have magnetic properties. The aim of the coating C18/SiO2/[3(2-Aminoetilamino) propyl] trimethoxy silane was to protect these cores from physical degradation due to acids and bases, as well as the application of synthetic materials. The sono-coprecipitation method showed good results under N2 gas flow with the results of black crystals. The success of SiO2 and [3(2-Aminoethylamino) propyl coatings the transformation of the color showed Trimethoxy silane into brown and weight gain of the synthesis result. Analysis of XRD data showed that little Fe2O3 impurities were clarified by FTIR data showing the presence of amine groups from the starting material. The SEM-EDX and TEM showed a spherical shape with a core-shell system. The adsorption kinetics model was studied using two kinetics models for Cu2+ and Cr6+ ions. The results were demonstrated by the suitability of Cu adsorption to the pseudo order 1, with an adsorption rate of 0.0333 min-1, whereas for Cr corresponded to pseudo order 2 with an adsorption rate of 0.00536 gmM-1min-1.

Peranan Gracilaria verrucosa dalam Menurunkan Nitrogen (N) dan Mangan (Mn) Melalui Sistem Polikultur dan Monokultur Ahmad Fuad Masduqi; Munifatul Izzati
Media Farmasi Indonesia Vol. 9 No. 2 (2014): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.891 KB)

ABSTRACT Gracilaria verrucosa is one type of seaweed that has the potential to be exploited and developed mainly used in ponds. The aims of this research is to study the role of Gracilaria verrucosa in reducing the content of Nitrogen (N) and Mangan (Mn) in the sediment on the pond. This research is conducted in the village pond Mororejo, Kendal and in the Biology laboratory, department of Biology faculty of Sains and Mathematics Diponegoro University. This research was designed by random complete design. The research was the methods of shrimp monoculture, monoculture Gracilaria verrucosa and polyculture containing shrimp, milkfish and Gracilaria verrucosa. The resulted data was analized by Analysis of Variance (ANOVA) continued by real difference test Duncan Multiple Range Test (DMRT) in 95% significance level. The parameters in this research were N and Mn content in the sediment. The results showed that the content of N and Mn in sediments more on shrimp monoculture farming systems than in monoculture Gracilaria verrucosa and polyculture of Gracilaria verrucosa.

AKTIVITAS ANTIOKSIDAN DARI EKSTRAK DAUN PEPAYA DAN DAUN CENGKEH SECARA IN VITRO Novi Elisa; Yustisia Dian Advistasari; Ahmad Fuad Masduqi
Jurnal Ilmiah Kesehatan Ar-Rum Salatiga Vol 8, No 1 (2023)
Publisher : STIKES Ar-Rum Salatiga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36409/jika.v8i1.194

Indonesia kaya akan tanaman herbal yang belum banyak dibudayakan sebagai pengobatan, masyarakat memanfaatkan tanaman sebagai pewarna makanan, olahan minuman dan makanan lainnya. Perkembangan zaman masyarakat lebih memilih untuk menggunakan makanan siap saji sehingga kurang dalam memahami khasiat dan kandungan pada makanan tersebut. Radikal bebas memiliki efek yang relatif dan tidak stabil Antioksidan merupakan zat yang dapat mempertahankan dan melindungi tubuh dengan baik oleh penyebab senyawa radikal bebas. Tujuan dalam penelitian ini adalah menguji total flavonoid dan uji antioksidan dari bahan alam ekstrak daun pepaya dan daun cengkeh. Metode penelitian mengguanakan determinasi tanaman dengan pemilihan sempel yang segar, uji total flavonoid yaitu Kandungan flavonoid total ditentukan dengan spektrofotometri UV-VIS dengan panjang gelombang 500 ppm. Sedangkan pada uji antioksidan mengguanakan metode DPPH yang dihasilkan dengan nilai IC50. Hasil penelitian ini uji total flavonoid antara ekstrak dari daun pepaya dan ekstrak daun cengkeh yang dapat memiliki kandungan total flavonoid tebaik adalah ekstrak daun cengkeh dengan total (61.017±0.061), uji antioksidan yang kuat adalah ekstrak daun cengkeh dengan nilai IC50 31.19 %..

POTENTIAL FLAVONOID FRACTIONS OF PURPLE EGGPLANT SKIN (SOLANUM MELONGENA VAR. SERPENTINUM L. ) AS AN ANTIOXIDANT Wulandari, Wulandari; Masduqi, Ahmad Fuad
CENDEKIA EKSAKTA Vol. 9 No. 1 (2024)
Publisher : Universitas Wahid Hasyim

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31942/ce.v9i1.11721

Antioksidan merupakan senyawa yang dapat digunakan untuk mengatasi radikal bebas dengan cara menetralisirnya sehingga dampak negatif yang ditimbulkannya dapat dihindari. Antioksidan dapat diperoleh dari dalam tubuh maupun dari luar, misalnya senyawa aktif yang terdapat pada tumbuhan seperti terong ungu. Kulit terong ungu diketahui mengandung senyawa aktif fenolik, flavonoid, antosianin, saponin, dan alkaloid. Tujuan penelitian ini adalah untuk mengetahui potensi antioksidan fraksi flavonoid kulit terong ungu. Metode ekstraksi dilakukan dengan cara remaserasi; fraksinasi dilakukan dengan metode kromatografi kolom vakum dengan pelarut n-heksana, etil asetat, dan metanol dengan berbagai perbandingan. Metode DPPH digunakan untuk menguji antioksidan dari sampel. Hasil fraksinasi kulit terong ungu mengandung senyawa flavonoid, dan aktivitas antioksidan fraksi flavonoid kulit terong ungu sebesar 275,218 ppm.Kata kunci: fraksi, flavonoid, kulit terong ungu, antioksidanÂ Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â AbstractAntioxidants are compounds that can be used to deal with free radicals by neutralizing them so that the negative effects they cause can be avoided. Antioxidants can be obtained from inside the body or from outside, for example active compounds found in plants such as purple eggplant. Purple eggplant skin is known to contain active phenolic compounds, flavonoids, anthocyanins, saponins, and alkaloids. The aim of this research was to determine the antioxidant potential of the flavonoid fraction of purple eggplant skin. The extraction method is carried out by remaceration; fractionation is carried out by vacuum column chromatography method with n-hexane, ethyl acetate, and methanol as solvents in various proportions. The DPPH method is used to test antioxidants from samples. The results of purple eggplant skin fractionation contain flavonoid compounds, and the antioxidant activity of the purple eggplant skin flavonoid fraction is 275.218 ppm.Key Words: fractions, flavonoids, purple eggplant skin, antioxidants

GRANUL EFFERVESCENT EKSTRAK KULIT BAWANG MERAH (Allium cepa L.) SEBAGAI OBAT HERBAL PENGOBATAN INFEKSI BAKTERI Streptococcus pyogenes PENYEBAB FARINGITIS N, Ratih Wirdia; A, Niken Fitri; Amalia, Nuansa; M, Rian Rizki; Mudiana, NIta; Masduqi, Ahmad Fuad
Media Farmasi Indonesia Vol. 12 No. 2 (2017): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (665.31 KB)

ABSTRAKInfeksi saluran pernapasan atas (ISPA) seperti faringitis merupakan peradangan pada membran mukosa yang mendasari struktur tenggorokan, mempunyai gejala nyeri kepala yang hebat, demam atau menggigil, malaise, nyeri menelan, muntah dan mungkin batuk tapi jarang. Faringitis dapat disebabkan oleh infeksi bakteri Streptococcus pyogenes. Kulit bawang merah (Allium cepa L.)merupakan bagian tanaman yang diidentifikasi mengandung senyawaflavonoid, tanin dan saponin. Senyawa tersebut memiliki aktivitas antibakteri. Penelitian ini bertujuan untuk mengetahui potensi antibakteri ekstrak etanol kulit bawang merah dalam berbagai konsentrasi terhadap Streptococcus pyogenessecara in vitro. Kulit bawang merah diektsraksi menggunakan etanol 96% dengan metode maserasi, formulasi granul effervescent dan uji karakteristik fisik granul effervescent. Formulasi granul effervescent dibuat dengan konsentrasi efektif: 5% ekstrak kulit dari Allium cepa L. Uji karakteristik fisikgranul effervescent meliputi: tanggapan rasa, waktu larut, kelembaban, volume bulk, pengetapan, waktu alir dan sudut diam. Hasil penelitian menunjukkan bahwa ekstrak kulit bawang merah memiliki aktivitas antibakteri terhadap S. pyogenes penyebab faringitis dan formulasi granul effervescent memenuhi seluruh uji karakteristik fisik sediaan.

Pemanfaatan Ekstrak Daun Belimbing Wuluh Sebagai Bahan Dasar Formula Pastagigi dan Daya Antibakteri Streptococcus mutans Masduqi, Ahmad Fuad; Anggoro, A. Barry
Media Farmasi Indonesia Vol. 12 No. 1 (2017): Media Farmasi Indonesia
Publisher : SEKOLAH TINGGI ILMU FARMASI YAYASAN PHARMASI SEMARANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (179.811 KB)

ABSTRAK Tanaman yang tumbuh di Indonesia sebagian besar dapat digunakan sebagai bahan baku obat tradisional. Salah satu tanaman yang digunakan sebagai tanaman obat yaitu belimbing wuluh ( Averhoa bilimbi L.). Ekstrak daun belimbing wuluh akan digunakan sebagai bahan dasar formula pastagigi dan diuji daya antibakterinya. Tujuan penelitian ini untuk mengetahui perbandingan ekstrak daun belimbing wuluh terhadap karakteristik fisik sediaan pastagigi. Selain itu, untuk mengetahui daya antibakterinya terhadap Streptococcus mutans. Penelitian ini dilaksanakan di Laboratorium Biologi Farmasi STIFAR “Yayasan Pharmasi” Semarang. Analisis data menggunakan Analisis of Variance (ANOVA) dilanjutkan uji beda nyata pada taraf signifikasi 95%. Parameter yang diamati meliputi karakteristik fisik sediaan pastagigi (organoleptis, pH, homogenitas, daya sebar, daya lekat dan viskositas) dan zona hambat antibakteri. Hasil penelitian menunjukkan bahwa perbandingan ekstrak daun belimbing wuluh berpengaruh terhadap karakteristik fisik sediaan pastagigi. Semakin besar konsentrasi ekstrak daun belimbing wuluh maka warna pastagigi berbeda, daya lekat semakin lama, daya sebar semakin kecil dan nilai viskositas semakin besar. Sediaan pastagigi dari ekstrak daun belimbing wuluh memiliki aktivitas antibakteri terhadap bakteri Streptococcus mutans pada konsentrasi efektif 20%.

Co-Authors A, Niken Fitri Achmad wildan Achmad Wildan Advistasari, Yustisia Dian Amalia, Nuansa Anggoro, A. Barry Aries Koes Sundoro Diah Permata Wijayanti Diah Permata Wijayanti Elisa, Novi Endang Saptiningsih Erma Prihastanti erna prasetyaningrum Erwin Indriyati Franyoto, Yuvianti Dwi Franyoto, Yuvianto Dwi Indriyanti, Erwin Kristantri, Rika Sebtiana Lia Kusmita Lia Kusmita Lutfhi Berlian Shandra M, Rian Rizki Ma’arif, Mohammad Naufal Syahrul Muchlisin, Sakti Mudiana, NIta Munifatul Izzati Munifatul Izzati N, Ratih Wirdia Novi Elisa Nurhartanti, Erli Puji Prastyo Abi Widyananto Purwaningsih, Yuliana Radix R , M. Ryan Rahardhian, Muhammad Rahmawati Salsa Dinurrosifa Rohmah, Syifaur Sakti Muchlisin Salsabila, Karisma Putri Sulistiyani Sulistiyani Sulistyani Sulistyani Susanti Hp, Eka Syukur, Mighfar verdia M, Erlita Wulan Kartika Sari Wulandari Wulandari Yustisia Dian Advistasari

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