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Journal : INDONESIAN JOURNAL OF PHARMACY

Single dose trypanocide surveillance of diminazene aceturate on mice infected by trypanosoma Lazuardi, Mochamad
Indonesian Journal of Pharmacy Vol 16 No 4, 2005
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (175.454 KB) | DOI: 10.14499/indonesianjpharm0iss0pp222-226

Abstract

Diminazene aceturate is one of a limited number compounds currently market for treatment infection cases of infection blood eucaryot parasits llike a Leishmania, and Trypanosoma The research design of this research was post test only control groups design for founding single therapeutics dose of the eukariyot parasite blood. The serial range dose of this research was used at 1,5 to 4 mg/kg bw by intraperitoneal administreted to infected mice (Mus musculus albinus) of the Trypanosoma evansi Bangkalan isolates. The result of this research showed the minimum single therapeutics dose at 3,5 mg/kg bw (p