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All Journal CAKRA KIMIA (Indonesian E-Journal of Applied Chemistry) INDONESIAN JOURNAL OF LEGAL AND FORENSIC SCIENCES Journal Pharmaceutical Science and Application (JPSA) Buletin Udayana Mengabdi Jurnal Farmasi Udayana Indonesian Journal of Pharmaceutical Science and Technology Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Bali Membangun Bali Humantech : Jurnal Ilmiah Multidisiplin Indonesia Sains Medisina Prosiding Workshop dan Seminar Nasional Farmasi (WSNF) Svāsthya: Trends in General Medicine and Public Health
Ni Kadek Warditiani
Program Studi Farmasi Universitas Udayana
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Public Health Social Sciences Transportation Other

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Review potensi Emblica officinalis (Amla) dalam mengatasi gangguan metabolisme dislipidemia dan antioksidan Ni Kadek Warditiani; Pande Made Nova Armita Sari; Ni Made Widi Astuti; I Made Agus Gelgel Wirasuta
Jurnal Farmasi Udayana Vol. 12, No 1, Tahun 2023
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JFU.2023.v12.i01.p10

Abstract

Emblica officinalis (Amla) is a plant that is not widely utilized in Bali, but it has tremendous potential. This study aims to investigate the antioxidant and anti-dyslipidemia potential of Amla. Literature search was conducted on Pubmed, Scopus, and Science Direct, followed by screening and review to match the inclusion and exclusion criteria. The search resulted in 346 articles, and after reviewing and screening the titles, keywords, and abstracts, 12 articles that met the criteria were obtained. The review findings indicate that Emblica officinalis (Amla) has a strong potential in preventing or addressing cardiovascular disorders such as atherosclerosis due to its abilities as a potential anti-dyslipidemia and antioxidant agent.
Uji Sifat Fisik dan Mikrobiologi Sediaan Lulur Krim yang Mengandung Serbuk Kopi serta Penentuan Aktivitas Antioksidannya Ni Kadek Warditiani
Jurnal Farmasi Udayana Vol. 12, No 1, Tahun 2023
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/JFU.2023.v12.i01.p11

Abstract

In 2017 the Ministry of Industry noted Indonesia’s cosmetics industry in the country out numbered to 760 companies. Further,95% of the industry is dominated by small to medium industrial sector, for this reason, in order to comply with international standards and certification bodies, it is necessary to guarantee the product quality. One of the product tested was a cream scrub containing coffee. Coffee has various chemical compounds that have antioxidant activity which plays a very important role in preventing premature aging. The product quality testing carried out is physical testing, microbiology and also the determination of antioxidant activity. From the prior tests, it was found that the pH of the preparation was 5.73 for the type of oil-in-water emulsion, the spreadability was 5.34 and 6.29 cm. Adhesion 11.10 seconds. The preparation meets all microbiological requirements and has an IC50% of 69.09 ppm.
Review Artikel Beyond Use Date Sediaan Steril Rekonstitusi wahyuni, LP eka; Warditiani, Ni Kadek; Suryani, N.P Febri; Sugiantara, I.W Eka; Rahayu, N.P Savitri; Dewi, N.P Apsari; Jayanti, N.K.P Aprilia; Adi P.S, I.K; Chantika P, N.K; Bayu J.K, I.M; Diah K, Shinta
Jurnal Farmasi Udayana Vol. 13, No. 1, Tahun 2024
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

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Abstract

Beyond Use Date (BUD) is the last date on which a medicinal preparation is considered stable and safe for use after reconstitution or preparation. Determination Beyond Use Date (BUD) functions to keep injection preparations sterile, protected from contaminants, protected from physical and chemical degradation. The method used in preparing this article is based on pharmaceutical literature, especially related literature steril coumponding method and pharmaceutical libraries. The purpose of this review article is to find out the importance of information regarding the BUD of reconstituted sterile preparations and how to use the drug after reconstitution. Determination of BUD for sterile preparations based on literature review United states of Phamacophea, American Society of Health-System Pharmacists (ASHP), and national and international published journals. The results of the article preparation are that the BUD determination is based on factors such as the chemical, physical and microbiological stability of the diluted drug. Reconstitution injection is a process in which a drug in dry form, such as powder or crystals, is converted into an injectable solution by adding a certain solvent or liquid. Quality requirements for reconstituted preparations include criteria that must be met by medicinal preparations after the reconstitution process to ensure their quality, safety and effectiveness. There are obstacles in determining the BUD for sterile preparations because the BUD time available is shorter after reconstitution, so there are several solutions that can be applied to maintain the stability of the preparation.
Literatur Review: Gambaran Pengetahuan Masyarakat Mengenai Beyond Use Dates Obat Racikan Padat Non Steril Prascitasari, Ayu; Warditiani, Ni Kadek; Septiarini, Putu Ayudia; Permatasari, Ni Made Ayu Dinda; Ananda Putri, Ida Ayu Ngurah Trisna Noviani; Andika, Dewa Made Dwi; Candrayani, Komang Tri; Arkhania, Ni Putu Ayu Dhea; Sanjaya, Sadina Vania Tsany Dyah; Ariswari, Ni Kadek Putri; Nugrahaeni, Luh Gede Ratih Dewi Tri
Jurnal Farmasi Udayana Vol. 13, No. 1, Tahun 2024
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

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Abstract

Kurangnya pemahaman masyarakat terkait Beyond Use Date (BUD) disebabkan oleh minimnya informasi yang diberikan oleh tenaga kesehatan mengenai hal tersebut. BUD merupakan batas waktu obat bisa dikonsumsi setelah kemasan primernya dibuka. Metode yang digunakan dalam penyusunan artikel ini didasarkan pada Literatur Review mengenai penerapan Beyond Use Date (BUD) pada obat campuran padat non-sterile. Artikel yang dipilih telah memenuhi kriteria inklusi yang telah ditetapkan yaitu artikel yang terpublikasi pada tahun 2014-2024. Hasil yang diperoleh yaitu peningkatan pengetahuan masyarakat setelah diberikan sosialisasi terkait BUD tentang pengertian BUD, perbedaan BUD dan ED pada tablet, kapsul, obat racikan, dan non racikan. Sediaan padat harus memiliki BUD paling lambat sama dengan sisa waktu sampai tanggal kadaluarsa zat aktif terawal dalam sediaan atau 180 hari, dipilih yang paling singkat.
Penumbuh Rambut Hair Tonic Aloe vera secara in vivo pada Kelinci Warditiani, Ni Kadek; Armita Sari, Pande Made Nova; Maha Dewi, Ni Kadek Santi; Natalia Kote, Jessica Christy
Jurnal Farmasi Udayana Vol. 13, No. 1, Tahun 2024
Publisher : Departement of Pharmacy, Faculty of Mathematics and Natural Science, Udayana University

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Abstract

Hair loss is an event of hair loss from the scalp that occurs regularly. However, hair loss becomes a problem if the amount of loose hair exceeds the normal limit. A hair tonic serves as a base for taking care of the hair and scalp. Aloe vera is often used as a hair care ingredient. In addition, this natural ingredient has the function of accelerating hair growth and reducing hair loss. Another natural ingredient used in making hair tonic is patchouli oil, which of course has a distinctive smell. The intention of this examine became to assess the effectiveness of a mixture of aloe vera and patchouli oil as a hair tonic for hair growth. In this study using a rabbit ridge which will be divided into 5 treatment groups with each different treatment. The treatment group that was given consisted of normal control, negative control (basic hair tonic), comparison control (hair tonic on the market), treatment control 1 (hair tonic given every 2 days) and treatment control 2 (hair tonic given 3 times). once a day). The test results were carried out by measuring the length of the rabbit's hair every 7 days for 21 days. One Way ANOVA and the LSD test were then used to statistically test the collected data. The study's findings demonstrated that a hair tonic consisting of aloe vera and patchouli oil, administered once every three days, significantly (p<0.05) accelerated the development of hair in rabbits.
Review Article: Akar Pule Pandak (Rauwolfia serpentina) Sebagai Antihipertensi Ratih, Ayu Putu Pramana Maha; Warditiani, Ni Kadek
Sains Medisina Vol 2 No 6 (2024): Sains Medisina
Publisher : CV. Wadah Publikasi Cendekia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63004/snsmed.v2i6.414

Abstract

Hipertensi adalah penyakit karena tekanan darah sistolik di atas 140 mmHg dan diastolik di atas 90 mmHg. Data riskesdas 2018 menunjukkan bahwa Indonesia, 34,1% penduduk usia di atas 18 tahun menderita hipertensi. Kasus hipertensi terbanyak di Kalimantan Selatan 44,1% dan terendah di Papua 22,2%. Studi tentang Rauwolfia serpentina sebagai obat masih jarang. Rauwolfia serpentina merupakan salah satu sumber senyawa bioaktif yang berpeluang dalam bidang farmasi untuk pengobatan hipertensi. Tujuan review artikel ini dilakukan untuk memberikan informasi dan edukasi tanaman Rauwolfia serpentina dengan fokus pada kandungan senyawa dan potensinya sebagai antihipertensi sehingga dapat digunakan pengobatan alternatif hipertensi. Review artikel ini dibuat dengan metode studi pustaka dari kumpulan jurnal nasional, jurnal internasional, dan buku. Berbagai penelitian diperoleh bahwa ekstrak akar Rauwolfia serpentina dapat menurunkan tekanan darah baik sistolik maupun diastolik.
Review artikel : Potensi tanaman sebagai anti diare Mutmainah, Susanti; Ni Kadek Warditiani
Humantech : Jurnal Ilmiah Multidisiplin Indonesia Vol. 2 No. Spesial Issues 3 (2022): Humantech : Jurnal Ilmiah Multidisiplin Indonesia
Publisher : Program Studi Akuntansi IKOPIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32670/ht.v2iSpesial Issues 3.1496

Abstract

Diarrhea is a condition in which excessive bowel movements with stools that are not forming or liquid with a frequency of more than 3 times in 24 hours. Diarrhea that lasts less than 2 weeks is known as acute diarrhea. Treatment of acute and chronic diarrhea can be done using modern medicine or traditional medicine. With the development of today's modern world, herbal medicine is still popularly used by rural communities. However, currently, the use of various traditional herbs for medical treatment continues to increase. Traditional treatment of disease using herbal plants is called phytotherapy. The purpose of writing this review article is to find out which plants have the potential as antidiarrheals. The method used is by conducting a literature study related to plants that have antidiarrheal activity found in national and international journals published in the last 10 years. From the results of a literature study, it was found 7 plants that have antidiarrheal activity including Guava Leaves (Psidium guajava L. ), Neem Leaves (Azadirachta indica Juss), Melinjo Fruit Peel (Gnetum gnemon L.), Ciplukan Leaves (Physalis angulata L.), Rhizome Turmeric (Curcuma domestica Val.), Senggani Leaf (Melastoma malabathricum L.), and Meat Remek Leaf (Hemagraphis colorata Hall F).
Review Artikel: Aktivitas Antiulcer Dari Tanaman Famili Zingiberaceae Kinanti, Novi Sekar; Ni Kadek Warditiani
Humantech : Jurnal Ilmiah Multidisiplin Indonesia Vol. 2 No. Spesial Issues 3 (2022): Humantech : Jurnal Ilmiah Multidisiplin Indonesia
Publisher : Program Studi Akuntansi IKOPIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32670/ht.v2iSpesial Issues 3.1502

Abstract

Peptic ulcer is commonly known as gastrointestinal disease due to disturbance of normal equilibrium caused by an increase or decrease in mucosal ulceration resistance. The main risk factors for peptic ulcers are Helicobacter pylori infection and the use of non-steroidal anti-inflammatory drugs (NSAIDs). Prevention or treatment of peptic ulcers can be done by using medicinal plants that have an antiulcer effect. One of the plant families that has great potential to be used as medicine is the Zingiberaceae family, which has a gastroprotective effect. This review article was compiled with the aim of determining plants with antiulcer potential from the Zingiberaceae family. Literature study was conducted on national and international journals related to Zingiberaceae family plants that have antiulcer activity, published in the last 10 years. Referring to the results of the literature study, 8 plants of the Zingiberaceae family were successfully identified as having potential as antiulcer, including Zingiber Officinale plants with the active compound of 6-gingesulfonic acid; Zingiber cassumunar with the active compounds of alkaloids, flavonoids, saponins, tannins, quinones, and steroids; Curcuma xanthorrhiza with the active compound of curcuminoid; Curcuma longa with the active compound of curcumin; Alpinia galang with the active compound of 1’acetoxy chavicol acetate, flavonoids and saponins; Kaempferia galanga with the active compound of p-methoxy cinnamic acid; Aframomum melegueta with the active compound of 6-Paradol; and Elettaria Cardamomum with the active compound of αphellandrene.
Review artikel: Potensi daun sirih hijau (piper betle l.) dan daun sirih merah (piper crocatum) sebagai antioksidan Kopong, Maria Vianey Uma; Ni Kadek Warditiani
Humantech : Jurnal Ilmiah Multidisiplin Indonesia Vol. 2 No. Spesial Issues 3 (2022): Humantech : Jurnal Ilmiah Multidisiplin Indonesia
Publisher : Program Studi Akuntansi IKOPIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32670/ht.v2iSpesial Issues 3.1504

Abstract

Green Betel (Piper betle.) and Red Betel (Piper crocatum) plants belong to the genus Piper from the Piperaceae family. It is known that the leaves of the betel plant have some bioactivity and are used in traditional medicine systems. Many research studies on the betel plant have reported that it contains important chemical components which have pharmacological effects, one of which is as an antioxidant. In this review, we discuss extracts from green and red betel plants as antioxidants and the phytochemical content contained therein. The review that has been made states that the green and red betel leaf extracts have antioxidant activity with a widely used method, namely DPPH (2,2-diphenyl-1-picrylhydrazy) with the results of antioxidant activity tests from the latest journal showing that the n-hexane fraction is more active as an antioxidant. Antioxidant (IC50 26.73 mg/L) compared to the diethyl ether fraction (IC50 114.54 mg/L). The phytochemical content of green and red betel leaf extract is positive for various secondary metabolites such as flavonoids, saponins, terpenoids, steroids, tannins, alkaloids, and phenolic compounds.
Review Artikel: Aktivitas Antioksidan Ekstrak Amla (Phyllanthus emblica / Emblica officinalis) Asih, Diah Jenari; Ni Kadek Warditiani; I Gede Sandi Wiarsana
Humantech : Jurnal Ilmiah Multidisiplin Indonesia Vol. 1 No. 6 (2022): Humantech : Jurnal Ilmiah Multidisiplin Indonesia
Publisher : Program Studi Akuntansi IKOPIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32670/ht.v1i6.1533

Abstract

The production of free radicals that exceeds the need will cause various degenerative diseases. Therefore, to protect itself from free radicals, the body produces anti-free radical compounds or so-called antioxidants. Antioxidants are compounds that are able to inhibit damage caused by free radical oxidation. Natural antioxidant compounds may be sourced from several plants, one of which is the Amla plant (Phyllanthus emblica L.). The antioxidant activity of Amla extract is due to the presence of phenolic compounds such as gallic acid and flavonoids as well as the content of ascorbic acid. This is because these three compounds contain hydroxyl groups that can donate hydrogen atoms to free radical compounds and stabilize reactive oxygen species (ROS). The purpose of writing this review article was to determine the potential of Amla (Kemloko) as an antioxidant. The method used in this article review was a literature study related to the benefits of Amla extract as an antioxidant through a literature search process using research articles from the last 10 years. Based on the conducted research, it shows that Amla extract has the potential as a natural antioxidant.
Co-Authors Ade Winanda Pangestu Adi P.S, I.K Agus Adi Purnama Putra Ananda Putri, Ida Ayu Ngurah Trisna Noviani Andika, Dewa Made Dwi Ariswari, Ni Kadek Putri Arkhania, Ni Putu Ayu Dhea Armita, Pande Made Nova Artini, P. E. U. D Asih, Diah Jenari Astarina, N. W. G. Astuti N.M.W. Astuti, K. W. Astuti, K.W. Astuti, Ni Made Widi Bayu J.K, I.M Budiman, I.N.A C. Juwianti Candrayani, Komang Tri Chantika P, N.K Cokorda Istri Sri Arisanti Dewa Ayu Swastini Dewa, Julio Angga Purnama Dewi K. A. S. Dewi P.E.M.U Dewi S.M. Dewi Wulandari Dewi, A.A.A.P.K. Dewi, I Gst A A Gangga Samala Dewi, I Gusti Ayu Widha Paramistya Dewi, I.D.A.D.Y. Dewi, N.P Apsari Dewi, N.P.A.K. Dewi, Ni Kadek Santi Maha Dewi, Ni Pande Kadek Sinta Dharmapradnyawati N.N.P. Diah K, Shinta G.D. Pranawa Gitarini N. M. Hapsari, Meivanti Diva I Gede Sandi Wiarsana I Ketut Adnyana I Made Agus Gelgel Wirasuta I N.K. Widjaja I Nyoman Arsana I Nyoman Arsana, I Nyoman I Putu Sudiartawan I Wayan Martadi Santika I. Damanik, I. N. T. Wisesa I.A.T Dewi I.B.D Esa I.M.K.A Suyadnya I.M.S. Sapanca Ida Bagus Putra Suta Ida Bagus Wiryanatha IG.Y Prayadnya IK.A.Y. Murti Indrani, A.A.I. S. Indriani N. P. W. Indyayani I.G.A Jayanti, N.K.P Aprilia Juniari N.P.M. K. Megayanti Kadek Dian Widyapurwanti Kinanti, Novi Sekar Komang Tri Farmani Kopong, Maria Vianey Uma Luh Putu Febryana Larasanty M. A. P. P. Rashid M. Primantara Made Galu Putra Ardiana Maha Dewi, Ni Kadek Santi Maruli Davidson Sitompul Milawati Milawati Mutiarani Dasha Hanggaresty Mutiarani Dasha Hanggaresty Mutmainah, Susanti N.K.A. Suksmawati N.K.I.P Dewi N.L.P.A Pratiwi N.M. Febrianti N.M. Suryaningsih N.P. Widiastuti N.P.R.A Putri N.P.R.D. Putri N.W.W Citradewi Nasya Nathania Chandra Natalia Kote, Jessica Christy Ni Luh Gede Sudaryati Ni Luh Putu Putri Dewi Ni Made Pitri Susanti Ni Made Widi Astuti Ni Made Widi Astuti Ni Made Widiastuti Ni Putu Eka Leliqia Ni Putu Linda Laksmiani Ni Putu Wahyudewi Primananda Noviyanti N. W. R Noviyanti, Ni Putu Rika Nugrahaeni, Luh Gede Ratih Dewi Tri Nugroho A.E. Oka M. P.A. Pramana, P.A. Savitri, P.P.K. Vedawati P.R. Satriari Padmanaba I.G.P. Padmasari, P.D. Pande Made Nova Armita Pande Made Nova Armita Sari Pande Made Nova Armita Sari, Pande Made Nova Permatasari, Ni Made Ayu Dinda Pinangkaan, C. Pramono S. Prascitasari, Ayu Prasetya, I Wayan Sindhu Wahyu Putri, Lucienne Agatha Larasati Nugraha Putri, W. S. Putu Dinda Pradnya Putri Permatasari Putu Lakustini Cahyaningrum Putu Oka Samirana R. Wirayanti Rahayu, N.P Savitri Rajeswari, Ni Kadek Ida Ratih, Ayu Putu Pramana Maha Rismayanti, A. A. M. I. Sanjaya, Sadina Vania Tsany Dyah Sanjiwani, P. Sarasmitha M.A Sarayawati, Kadek Ayu Mas Sari , Putri Ayu Puspita Sari, N. A. P. P. Septiarini, Putu Ayudia Setyawan E.I Setyawan E.I. Siahaan, T. F. Silalahi, Lydia Devy Sudiartawan, I Putu Sugiantara, I.W Eka Suhendi, Jessica Rianty Sunariyani, P. E. A. Suryani, N.P Febri Susanti, N.M.P Suta, Ida Bagus Putra Swasti, I.A.S. Talitha Amanda Hartono wahyuni, LP eka Wahyuni, N.N.S Wahyuni, Ni Luh Komang Widhiastuti, K.A.P. Widjaja I N.K. Widjaja I. N. K Widjaja I.N.K Widjaja I.N.K. Widjaja, I. N. K. Widjaja, I.N.K Wijayanti, N.L.P.D Windarini, L.G.E. Wiputri N.M.C.A.