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All Journal HAYATI Journal of Biosciences Journal of Food and Pharmaceutical Science Jurnal Matematika & Sains Indonesian Journal of Tropical and Infectious Disease UNEJ e-Proceeding Jurnal Kimia Riset Indonesian Journal of Chemistry Jurnal Layanan Masyarakat (Journal of Public Service) Journal of Food and Pharmaceutical Sciences Bulletin of Chemical Reaction Engineering & Catalysis Journal of Bio-molecule Research And Engineering Andan Jejama: Indonesian Journal Of Community Engagement
Nanik Siti Aminah
Departemen Kimia, Fakultas Sains Dan Teknologi, Universitas Airlangga
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Education Environmental Science Health Professions Immunology & microbiology Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Public Health Social Sciences Other

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Journal : Indonesian Journal of Chemistry

 1 
(-)-AMPELOPSIN A : A DIMER RESVERATROL FROM Dryobalanops oblongifolia (dipterocarpaceae) Nanik Siti Aminah; Sjamsul Arifin Achmad; Masatake Niwa; Yana Maolana Syah; Euis Holisotan Hakim
Indonesian Journal of Chemistry Vol 6, No 1 (2006)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (227.094 KB) | DOI: 10.22146/ijc.21778

Abstract

A dimer resveratrol compound named (-)-ampelopsin A was isolated from acetone extract of the stem bark of  Dryobalanops oblongifolia (Dipterocarpaceae). The structure of this compound was determined on the basis of NMR spectroscopic data.
Design of Catechin-based Carbon Nanodots as Facile Staining Agents of Tumor Cells Yaung Kwee; Alfinda Novi Kristanti; Nanik Siti Aminah; Mochamad Zakki Fahmi
Indonesian Journal of Chemistry Vol 20, No 6 (2020)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.50327

Abstract

Carbon nanodots (CNDs) have widely received great attention as a result of favorable optical, electrical, optoelectrical, biocompatible, and non-toxic properties these nanoparticles possess. However, the exploration of nanoparticle from natural raw material was limited. In present work, the carbon dots were produced from catechin isolated from Uncaria gambir through a simple and facile process. Carbon nanodots were further produced by the pyrolysis process of catechin, which allowed it for carbonization. Owing to its unique properties such as photoluminescence with an emission peak at 500 nm (lex = 380 nm), average size diameter about 5 nm and non-toxic; Cat-CNDs were incredibly potential for staining targeted tumor cells. The staining ability by confocal microscopy observations showed their green fluorescence images which meant that the CNDs easily penetrated HeLa cells via endocytosis. The resulting CNDs which were analyzed using some significant techniques approved that the prepared Cat-CNDs were tremendously dispersible and water-soluble, good colloidal stability, excellent biocompatibility, favorable hydrophilicity, high photostability, and non-toxicity.
The Use of Chemometrics for Classification of Sidaguri (Sida rhombifolia) Based on FTIR Spectra and Antiradical Activities Abdul Rohman; Asefin Nurul Ikhtiarini; Widiastuti Setyaningsih; Mohamad Rafi; Nanik Siti Aminah; Muhamad Insanu; Irnawati Irnawati; Djoko Santosa
Indonesian Journal of Chemistry Vol 21, No 6 (2021)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.64360

Abstract

Sidaguri (Sida rhombifolia) is one of the herbal components used in traditional medicine. The application of chemometrics in the standardization of herbal medicine is common. The objective of this study was to classify Sidaguri from different regions based on FTIR spectra with chemometrics of principal component analysis (PCA) and to correlate the antioxidant activities with FTIR spectra using the multivariate calibration of partial least square regression (PLSR). The extraction of Sidaguri powder was performed using ultrasound-assisted extraction (UAE) at optimum conditions. The obtained extracts were subjected to antiradical scavenging activities using DPPH (2,2’-diphenyl-1-picrylhydrazyl) and ABTS (2,2′-azinobis-3-ethylbenzothiazoline-6-sulfonic acid) radicals. The PCA result shows that Sidaguri from different regions could be separated using 14 wavenumbers of FTIR spectra based on the PCA's loading plot. PLSR regression using the second derivative FTIR spectra at wavenumbers of 3662–659 cm–1 could predict radical scavenging activities (RSA) of Sidaguri with R2 values of 0.9636 and 0.9024 for calibration and validation models, with RMSEC and RMSEP values of 1.45% and 2.65%, respectively. It can be concluded that FTIR spectra treated by PCA were reliable for classifying Sidaguri from different regions. At the same time, PLSR was accurate and precise enough to predict the RSA of Sidaguri.
Identification of Sida rhombifolia from Its Related Plants Using Thin-Layer Chromatographic Analysis Mohamad Rafi; Sefni Reza Yolanda; Dewi Anggraini Septaningsih; Maria Bintang; Nanik Siti Aminah; Muhamad Insanu; Abdul Rohman
Indonesian Journal of Chemistry Vol 23, No 1 (2023)
Publisher : Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijc.73077

Abstract

Sida rhombifolia belongs to the Malvaceae family and is often used to treat gout in Indonesia. S. rhombifolia has many efficacies and contains many different chemical components. The abundance and variation of chemical content and chemical compounds in this medicinal plant are challenging factors in ensuring medicinal plants' safety and quality control. Thin-layer chromatography (TLC) fingerprint analysis derived from S. rhombifolia extract can also be used for the medicinal plant's quality control. This research aimed to develop the optimum condition for the chemical fingerprint analysis of S. rhombifolia using a TLC fingerprint analysis. A total of 11 bands were produced with optimum separation using silica gel 60 F254 TLC plate, a mixed mobile phase condition with chloroform, ethyl acetate, and methanol (6.5:2:1.5). This fingerprint analysis performed an excellent separation in the TLC plate at 366 nm with sulfuric acid as reagent derivatization. In general, the results of the analysis validation, including stability, specificity, precision, and robustness of TLC fingerprints, met the acceptance criteria. The TLC fingerprint of S. rhombifolia can be distinguished from 2 related plants with similar leaf shapes, Turnera ulmifolia L. and Hibiscus rosa-sinensis. The developed method was validated, so it could be used to control S. rhombifolia quality.
Co-Authors Abdjan, Muhammad Ikhlas Abdul Rohman Abdul Rohman Abdul Rohman Abdul Rohman Abdullah Abdulloh Abdulloh Abdulloh Alfa Akustia Widati Alfi Hudatul Karomah Alfian, Fariz Rizky Alfinda Novi Kristanti Alsya Firdausi Nuzula Alsya Firdausi Nuzula Ana Firdausyah Andika Pramudya Wardana Andika Pramudya Wardana Asefin Nurul Ikhtiarini Asma Asma Auliya Ilmiawati Azalea Rahma Septianti Baharin, Siti Nor Atika Budi Prasetyo, Antonius Choirotul Isma Citra Putri Pramitha Didik Prasetyoko Didik Prasetyoko Didik Prasetyoko Djoko Santosa Emilia L. Ghisalberti Euis Holisotan Hakim Euis Holisotasn Hakim Ganden Suprianto Giman Giman Haq, Kautsar Ul Hariyanto, Geraldo Figo Hery Suwito Imam Siswanto Irnawati Irnawati Irnawati Irnawati Khoso, Mir Hasan Khusnul Wardah Mukharomah Lia Dewi Juliawaty Mahmiah Maria Bintang Marisa Nur Sahadatin Marisa Nur Shahadatin Masatake Niwa Mochamad Zakki Fahmi Mohamad Rafi Mohamad Rafi Mohamad Rafi Mohamad Rafi Mudasir Mudasir Mudasir Mudasir Muhamad Insanu Mulyadi Tanjung Nita Citrasari NUrina Fitriani, NUrina Qonitah Labibah Rico Ramadhan, Rico Rimuljo Hendradi Rusdipoetra, R. Aryabraga Satya Candra Wibawa Sakti Sefni Reza Yolanda Septaningsih, Dewi Anggraini Setyaningsih, Widiastuti Siti Maryam Siti Maryam Sjamsul Arifin Achmad Sjamsul Arifin Achmad Suhaili, Suhaili Susilowati, Rina Priastini Syarifah Asyura, Syarifah Takaya, Yoshiaki Taufik Taufik Tio Christiawan Bramayudha Tokok Adiarto Triyono Triyono Triyono Triyono Utami Dyah Syafitri Wardana, Andika Pramudya Wega Trisunaryanti Wega Trisunaryanti Win Darmanto Yana Maolana Syah Yaung Kwee Yoshiaki Takaya Yoshiaki Takaya