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Ainun Nafisah
Food Technology Department Universitas Sultan Ageng Tirtayasa
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Engineering Environmental Science Immunology & microbiology Industrial & Manufacturing Engineering Materials Science & Nanotechnology Mechanical Engineering Public Health Social Sciences Other

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Peran Hormon Glukagon dalam Regulasi Metabolisme Energi dan Respon Stres pada Sapi Perah Periparturient: Literatur Review Maulidina, Fauziah; Maulana, Irpan; Putria, Devita Rahma; Tuzzahra, Maulida Andini; Nurrofingah, Ulfa; Nafisah, Ainun
Jurnal Sains Peternakan Nusantara Vol 5 No 02 (2025): Jurnal Sains Peternakan Nusantara
Publisher : Universitas Ma'arif Nahdlatul Ulama Kebumen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53863/jspn.v5i02.1903

Abstract

The periparturient period of dairy cows is a transitional phase starting from three weeks before to three weeks after parturition with physiological changes characterized by increased energy needs for lactation and decreased feed consumption, resulting in a negative energy balance (NEB) and metabolic stress. The periparturient glucagon hormone plays an important role in maintaining the balance of energy metabolism through the activation of glycogenolysis and gluconeogenesis in the liver to maintain blood glucose levels, as well as encouraging lipolysis of adipose tissue that produces non-esterified fatty acids (NEFA) as an alternative energy source. Glucagon plays a role in maintaining the balance of metabolic adaptation to reduce disorders, such as ketosis, fatty liver, and decreased early lactation. The main objective is to analyze the role of the glucagon hormone in regulating energy metabolism and stress responses that interact with other hormones and nutritional factors that influence the physiology and metabolism of periparturient dairy cows. The discussion covers three main aspects, namely (1) the physiological mechanism of glucagon in energy metabolism, (2) the interaction of glucagon with other hormones such as insulin, GH, IGF-1, and cortisol, and (3) the effect of medium-chain fatty acids (MCFA) supplementation and rumen-protected glutamate on the activity and stability of glucagon secretion as a stress response in periparturient dairy cows. The writing method uses a literature review approach based on the analysis of the latest scientific journals relevant to the energy metabolism of dairy cows. The results of the study indicate that glucagon is the main regulator in the integration of endocrine and metabolic responses, works synergistically with other hormones and is influenced by nutritional status to maintain homeostasis, and reduce physiological stress. In conclusion, optimizing hormonal balance and nutritional management is very important to support metabolic efficiency, dairy cow productivity, and reduce stress during the periparturient period
Peran Probiotik Terhadap Kesehatan Saluran Pencernaan dan Produktivitas Sapi Perah: Literatur Review Mulyani, Mila; Handini, Aulia Tri; Salsabila, Winda; Sutanto, Ridwan Hakim; Ilyas, Gian Wiguna; Nurrofingah, Ulfa; Nafisah, Ainun
Jurnal Sains Peternakan Nusantara Vol 5 No 02 (2025): Jurnal Sains Peternakan Nusantara
Publisher : Universitas Ma'arif Nahdlatul Ulama Kebumen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53863/jspn.v5i02.1938

Abstract

Probiotics are live microorganisms that have significant benefits for the health of ruminant livestock, especially dairy cattle, when administered in sufficient amounts. The use of probiotics in the modern livestock industry has been proven to improve digestive efficiency, stabilize rumen microflora, and increase milk productivity. Previous research indicated that probiotic strains such as Bacillus subtilis, Lactobacillus spp. dan Saccharomyces cerevisiae play an important role in improving rumen fermentation, increasing dry matter digestibility, and suppressing the growth of pathogenic microbes. The cow's digestive system begins in the mouth, then the food enters the esophagus to the rumen for fermentation, then to the omasum for water absorption, to the abomasum (true stomach), small intestine, large intestine, and then excreted. This review aims to analyze various research findings regarding the role of probiotics in the gastrointestinal health and productivity of dairy cattle, based on 20 nationally and internationally accredited scientific articles (SINTA 2 - 5 and Scopus) published between 2016 - 2025. The results of the study show that routine administration of probiotics can improve rumen health, increase feed conversion efficiency, and lead to significant increases in milk production and quality without negative effects on the livestock.
Peran Asam Lemak Tak Jenuh dalam Meningkatkan Kesehatan Metabolik dan Reproduksi Ternak Sapi Perah: Literatur Review Humairoh, Ati; Ramadhan, Firdaus; Sidik, Abdul Fathir; Ruslan, Muhammad; Fauzan, Ahmad; Nurrofingah, Ulfa; Nafisah, Ainun
Jurnal Sains Peternakan Nusantara Vol 5 No 02 (2025): Jurnal Sains Peternakan Nusantara
Publisher : Universitas Ma'arif Nahdlatul Ulama Kebumen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53863/jspn.v5i02.1941

Abstract

The transition period in dairy cows is a critical phase characterized by increased energy requirements with the onset of lactation, while feed intake is often insufficient to meet these demands, leading to negative energy balance (NEB) that adversely affects metabolic health and reproductive performance. Therefore, this literature review aims to evaluate the role of unsaturated fatty acid (UFA) supplementation, particularly polyunsaturated fatty acids (PUFA), in mitigating NEB and improving the physiological performance of dairy cows based on recent scientific findings published between 2016 and 2025. The results indicate that UFA supplementation, especially rumen-protected sources, contributes to improved energy balance, enhanced insulin sensitivity, improved oocyte and embryo quality, increased plasma progesterone concentrations, reduced systemic inflammation, and improved blood lipid profiles. In addition, UFA supplementation helps maintain milk yield while enhancing milk quality through increased levels of unsaturated fatty acids and conjugated linoleic acid (CLA). With appropriate formulation, dosage, and timing of supplementation, UFA represents an effective and sustainable nutritional strategy to improve metabolic health, energy efficiency, and reproductive performance in dairy cows
Co-Authors Ahmad Fauzan Aini, Fazriati Shofa Annazhifah, Nurul Armelia, Vony Bakti, Pramudya Dafa, Adji Muhammad Dzikribillah, Muhammad Dhabit Fahri, Mochamad Filki Ardiansyah Firdaus Ramadhan Fitria Riany Eris Gagah Hendra Wijaya, Gagah Hendra Hadiputra, Raafi Akbar Handini, Aulia Tri Hariyanti, Rahma Humairoh, Ati Ilyas, Gian Wiguna Ismail, Abiyyu Hassan Kania Asri Liany Kusumasari, Septariawulan Magfira Mardiyanti, Een Maulana, Irpan Maulidina, Fauziah Meindrawan, Bayu Mila Mulyani, Mila Mohamad Ana Syabana Muhammad Dhabit Dzikribillah Muhammad Ruslan Muztahidin, Nur Iman Nahrowi Nahrowi Najah, Zulfatun Nia Ariani Putri Nurrofingah, Ulfa Pangesti, Raiza Tri Puji Wulandari Puji Wulandari Kuncorowati Putri, Liana Putri, Nezly Nurlia Putri, Nia Ariani Putria, Devita Rahma Rifqi Ahmad Riyanto Riyanto, Rifqi Ahmad Roidelindho, Kiki Romadoni, Fathurrahman Bintang Salsabila, Winda Sidik, Abdul Fathir Sutanto, Ridwan Hakim Syafiyullah, Radian Syaifudin, Rizal Tubagus Bahtiar Rusbana Tubagus Bahtiar Rusbana, Tubagus Bahtiar Tuzzahra, Maulida Andini Vega Yoesepa Pamela Winda Nurtiana Zulfatun Najah