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Seorang Wanita dengan Cor Pulmonale Terkait Silikosis : [Cor Pulmonale in a Woman with Silicosis: A Case Report] Abdul Rahman Bahmid; Helmia Hasan
Jurnal Respirasi Vol. 5 No. 3 (2019): September 2019
Publisher : Faculty of Medicine Universitas Airlangga

Background: Silicosis is a pulmonary fibrosis disease caused by inhalation of silica crystals (silicon dioxide). Silica is a material that can be found everywhere which is the main component of the earth's crust. There are three main forms of silica crystals that cause lung injury, namely quartz, cristobalite, and tridymite. Quartz is the most commonly found silica in most rocks, including granite and sandstone. Case:A housewife aged 47 years experienced shortness since 1 month disappeared, and weighed the last 1 week. Shortness especially during activity. Cough once in a while, with white phlegm. Swelling in both legs since more than 1 month. There is no history of asthma, pulmonary TB, and DM. The patient is a housewife. About 15 years ago the patient had worked in a rubber factory for 2 years. Conclusion: Silicosis is always associated with pulmonary TB, because silicosis patients have a high risk of developing pulmonary TB. To detect the presence of pulmonary TB in these patients we have carried out smear smear and geneXpert tests of sputum specimens with negative results. Examination of M.tb from culture of induced sputum material has been carried out but the results have not been obtained.

Tinjauan Imunologi Pneumonia pada Pasien Geriatri Rizki Maulidya Putri; Helmia Hasan
Cermin Dunia Kedokteran Vol 41, No 1 (2014): Neurologi
Publisher : PT. Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v41i1.1166

Pneumonia menjadi salah satu masalah kesehatan utama pada geriatri. Karakteristik pneumonia pada pasien geriatri adalah presentasi klinisnya yang khas. Perubahan status imunologi akibat proses penuaan memberi konsekuensi penting terhadap cadangan fungsional paru, kemampuan untuk mengatasi penurunan komplians paru dan peningkatan resistensi saluran napas terhadap infeksi. Saat timus mengalami involusi karena pengaruh usia, terjadi penurunan produksi sel T naif, perubahan fungsi sel T memori, pergeseran profil sitokin dari Th1 ke Th2. Pada imunitas humoral terjadi penurunan jumlah sel B dan reseptornya, penurunan formasi germinal center, disfungsi generasi dari limfosit B primer, gangguan produksi sel B memori, peningkatan autoantibodi. Manajemen penting pada pasien geriatri meliputi terapi antibiotik dan pertimbangan perawatan di ICU, serta pencegahan episode ulangan.Pneumonia becomes one of the major health problems in the elderly. A characteristic of pneumonia in geriatric patients is its typical clinical presentation. Immunological status changes due to the aging process to give an important consequence of the pulmonary functional reserve, ability to cope with decreased lung compliance and increased airway resistance to infection. Thymus involution due to aging decreases naïve T cells production, changes memory T cell function, shifts the cytokine profile from Th1 to Th2. In humoral immunity, there are decrease of B cells and its receptors, decrease of germinal center formation, dysfunctional generation of primary B lymphocytes, impaired memory B cell production, and increase of autoantibodies. Management includes antibiotic therapy and considerations for ICU treatment, and prevention of further infection.

Factors Associated with the Level of Non-Adherence to Take Antituberculosis drugs Garuda Nusantara Putra Utomo; Helmia Hasan; Sulistiawati Sulistiawati
Journal Syifa Sciences and Clinical Research Vol 5, No 1 (2023): Volume 5 Edisi 1 2023
Publisher : State University of Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37311/jsscr.v5i1.15616

Non-adherence to take antituberculosis drugs is one of the causes of tuberculosis (TB) resistance. However, in Indonesia no study identified the factors associated with the level of non-adherence to take antituberculosis drugs in Multi-Drug Resistant Tuberculosis (MDR-TB) patients when they were still pulmonary drug-sensitive TB survivors. The aim of this study was to identify factors associated with the level of non-adherence to take antituberculosis drugs. This was a cross-sectional study which was conducted from October 2021 to December 2021 at Dr. Soetomo Hospital Surabaya. The dependent variable was the level of non-adherence to take antituberculosis drugs, while the independent variables were age, gender, education level, income, distance from home to health care service, role of health workers, role of superintendent of swallowing drugs (PMO), and side effects. Forty out of the 195 secondary-resistant MDR-TB patients were selected as subjects for this study based on their willingness. The instrument was questionnaire which had been tested for its validity and reliability. The results of bivariate analysis showed that gender, the role of PMO, and side effects had a significance of p0.05. The results of the bivariate analysis indicated that gender, role of PMO, and side effects have significance value p0.05. The conclusion of this study is gender, role of PMO, and side effects are associated with the level of non-adherence to take antituberculosis drugs.

Profil Pasien Systemic Lupus Erythematosus Dengan Manifestasi Kardiorespirasi Di Rsud Dr Soetomo Periode Januari - Desember 2018 Putri Dwi Amartya Kirana; Awalia Awalia; Helmia Hasan
Journals of Ners Community Vol 13 No 1 (2023): Journals of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i1.2498

Systemic Lupus Erythematosus (SLE) merupakan penyakit inflamasi autoimun kronis sistemik dimana sistem kekebalan tubuh menyerang jaringan dan organ tubuh itu sendiri. Penyebab penyakit autoimun ini belum dapat dijelaskan secara pasti. Manifestasi klinis penyakit SLE begitu beragam dan dapat mengenai berbagai organ tubuh. Beberapa manifestasi klinis pada pasien SLE antara lain yaitu adanya kelainan ada paru dan jantung. Penelitian ini bertujuan untuk mengetahui gambaran profil pasien SLE dengan manifestasi kardiorespirasi yang menjalani rawat inap di RSUD Dr.Soetomo Surabaya. Pengambilan sampel dilakukan dengan teknik total sampling yang berarti semua individu pada populasi yang memenuhi kriteria inklusi merupakan sampel. Jenis penelitian yang digunakan dalam penelitian ini adalah deskriptif dengan menggunakan data sekunder berupa rekam medis. Total sampel yang sesuai dengan kriteria inklusi berjumlah 74 pasien. Pasien didominasi oleh perempuan dengan kelompok usia terbanyak adalah usia 26-45 tahun. Sejumlah 22 pasien dilaporkan meninggal dengan penyebab terbanyak adalah syok sepsis. Manifestasi paru yang ditemukan berupa efusi pleura (30.6%), penumonitis lupus (28.6%), pneumonia (27%), edema paru (11.1%), hipertensi pulmonal (6.3%), tuberkulosis (6.3%), ILD (6.3%). Manifestasi jantung yang ditemukan adalah efusi perikardium (46.7%), insufisiensi katup mitral (30%), insufisiensi katup trikuspid (33.3%), insufisiensi katup pulmonal (6.7%), dilated cardiomypathy (6.7%), dan heart failure (13.3%). Kelainan laboratorium yang ditemukan adalah anemia 66.6%, limfopenia 75.3%, trombositopenia 37%. Terapi yang banyak diberikan berupa methylprednisolon, chloroquin, antibiotik ceftriaxone, dan levofloxacin. Pasien SLE dengan manifestasi kardiorespirasi didominasi oleh perempuan usia produktif. Penyebab kematian pada pasien SLE dengan manifetsasi kardiorespirasi terbanyak adalah akibat syok sepsis

The Frequency of Multidrug-Resistant Tuberculosis Patient who have History of Tuberculosis, HIV, and Diabetes Mellitus at Dr. Soetomo General Academic Hospital Marsha Zahrani; Rebekah J. Setiabudi; Helmia Hasan; Manik Retno Wahyunitisari
Current Internal Medicine Research and Practice Surabaya Journal Vol. 4 No. 1 (2023): CURRENT INTERNAL MEDICINE RESEARCH AND PRACTICE SURABAYA JOURNAL
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/cimrj.v4i1.42603

Introduction: The main causes of MDR TB include interperson transmission and TB treatment failure. In addition to TB, HIV and diabetes mellitus may raise the risk of TB MDR. To determine the TB MDR risk factors, it's critical to understand the prevalence of TB MDR patients with TB, HIV, and diabetes mellitus histories.Methods: This study is an observational descriptive study with a retrospective design. The sample for this study was all patients from the TB and MDR-TB polyclinic at Dr. Soetomo General Academic Hospital, Surabaya, in January 2020–December 2020 who met the inclusion criteria. The data obtained were analyzed descriptively.Results: There were 72 patients who met the criteria: there were 26 patients who have a history of TB, 15 patients who only have a history of diabetes mellitus, 2 patients who only have a history of HIV, 27 patients who have a history of TB with diabetes mellitus, and 2 patients who have a history of TB with HIV.Conclusion: The data could support the theory of an association between MDR-TB with TB, HIV, and diabetes mellitus and increase the awareness of primary MDR TB cases with history of HIV and diabetes mellitus.

Profil Pasien Systemic Lupus Erythematosus Dengan Manifestasi Kardiorespirasi Di Rsud Dr Soetomo Periode Januari - Desember 2018 Putri Dwi Amartya Kirana; Awalia Awalia; Helmia Hasan
Journals of Ners Community Vol 13 No 6 (2022): Journals of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i6.2760

Systemic Lupus Erythematosus (SLE) merupakan penyakit inflamasi autoimun kronis sistemik dimana sistem kekebalan tubuh menyerang jaringan dan organ tubuh itu sendiri. Penyebab penyakit autoimun ini belum dapat dijelaskan secara pasti. Manifestasi klinis penyakit SLE begitu beragam dan dapat mengenai berbagai organ tubuh. Beberapa manifestasi klinis pada pasien SLE antara lain yaitu adanya kelainan ada paru dan jantung. Penelitian ini bertujuan untuk mengetahui gambaran profil pasien SLE dengan manifestasi kardiorespirasi yang menjalani rawat inap di RSUD Dr.Soetomo Surabaya. Pengambilan sampel dilakukan dengan teknik total sampling yang berarti semua individu pada populasi yang memenuhi kriteria inklusi merupakan sampel. Jenis penelitian yang digunakan dalam penelitian ini adalah deskriptif dengan menggunakan data sekunder berupa rekam medis. Total sampel yang sesuai dengan kriteria inklusi berjumlah 74 pasien. Pasien didominasi oleh perempuan dengan kelompok usia terbanyak adalah usia 26-45 tahun. Sejumlah 22 pasien dilaporkan meninggal dengan penyebab terbanyak adalah syok sepsis. Manifestasi paru yang ditemukan berupa efusi pleura (30.6%), penumonitis lupus (28.6%), pneumonia (27%), edema paru (11.1%), hipertensi pulmonal (6.3%), tuberkulosis (6.3%), ILD (6.3%). Manifestasi jantung yang ditemukan adalah efusi perikardium (46.7%), insufisiensi katup mitral (30%), insufisiensi katup trikuspid (33.3%), insufisiensi katup pulmonal (6.7%), dilated cardiomypathy (6.7%), dan heart failure (13.3%). Kelainan laboratorium yang ditemukan adalah anemia 66.6%, limfopenia 75.3%, trombositopenia 37%. Terapi yang banyak diberikan berupa methylprednisolon, chloroquin, antibiotik ceftriaxone, dan levofloxacin. Pasien SLE dengan manifestasi kardiorespirasi didominasi oleh perempuan usia produktif. Penyebab kematian pada pasien SLE dengan manifetsasi kardiorespirasi terbanyak adalah akibat syok sepsis.

PROFIL KADAR CD4 PASIEN HIV KOINFEKSI TB PARU DI UNIT PERAWATAN INTERMEDIET PENYAKIT INFEKSI (UPIPI) RSUD DR. SOETOMO PERIODE JANUARI – DESEMBER 2019 Pranaya, Azhraa Qinan; Hasan, Helmia; Bramantono, Bramantono
Mitra Raflesia (Journal of Health Science) Vol 15, No 2 (2023)
Publisher : LPPM STIKES BHAKTI HUSADA BENGKULU

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51712/mitraraflesia.v15i2.327

ABSTRAKLatar Belakang : CD4 adalah komponen sistem imun manusia yang berperan sebagai pelindung dari infeksi yang menyerang tubuh. Menurut beberapa penelitian, pasien HIV/ AIDS yang memiliki kadar CD4 yang rendah dapat menaikkan risiko terkena koinfeksi penyakit menular, salah satunya yaitu; Tuberkulosis Paru. Penelitian ini bertujuan untuk Mengetahui gambaran kadar CD4 pasien HIV koinfeksi TB Paru di Unit Perawatan Intermediet Penyakit Infeksi (UPIPI) RSUD Dr. Soetomo periode Januari – Desember 2019.Metode : Penelitian ini adalah penelitian deskriptif retrospektif yang menggunakan rekam medik pasien. Penelitian ini menggunakan teknik sampling purposive non probability dengan metode pengambilan total sampling. Variabel yang diamati antara lain; usia, jenis kelamin, pendidikan terakhir, status pekerjaan, status perkawinan, faktor risiko penularan dan kadar CD4 pasien.Hasil : Pada penelitian ini, dari 45 subyek pasien HIV- TB Paru, terdapat 33 pasien subyek yang ter- inklusi. Dari 33 subyek tersebut, didapatkan kelompok usia didominasi oleh kelompok usia 26 – 35 (36,36%) dan jenis kelamin terbanyak didominasi oleh laki – laki (66,67%). Lalu, untuk tingkat akhir pendidikan pasien yaitu didominasi oleh kelompok dengan tingkat pendidikan akademi/ Perguruan Tinggi (PT) (36,37%). Untuk status pekerjaan pasien didominasi oleh kelompok dengan status bekerja (72,72%). Kadar CD4 pasien yang paling banyak dialami oleh subyek yaitu kelompok pasien < 200 sel/ µmL dengan persentase 87,88%.Simpulan : Kadar CD4 pasien yang paling banyak dialami oleh subyek yaitu kelompok pasien < 200 sel/ µmL dengan persentase 87,88%.Kata Kunci : HIV, Lung TB, CD4

Perceptions of COVID-19 Online Learning Students Based on Dreem in Class 2020 Students of the Faculty of Medicine Universitas Airlangga, Surabaya, Indonesia Mirza Nur Mazidah; Hasan, Helmia; Utomo, Budi
Journal of Community Medicine and Public Health Research Vol. 5 No. 2 (2024): Journal Community Medicine and Public Health Research
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jcmphr.v5i2.52852

A learning environment is anything that can influence changes in attitudes in teaching and learning activities which will further influence the achievement of learning outcomes and student development. A researcher wants to carry out research on student perceptions regarding changes in the online learning environment due to Coronavirus Disease 19 (COVID-19) in the Faculty of Medicine, Universitas Airlangga. The study aimed to describe the perceptions of the students toward five aspects of an online learning environment. This study was a descriptive research using a quantitive approach and the sampling technique used simple random sampling with 167 medical faculty student class 2020. One hundred sixty-seven respondents' data were collected using the specific measurement tool Dundee Ready Education Environment Measure (DREEM) to measure the learning environment with univariate analysis. The results obtained from this research showed that the perception of students at the Faculty of Medicine, Universitas Airlangga towards the online learning environment is quite good with a score of 139.48. The result of this study indicated that the mean DREEM score was 139.48/200 (SD 22.76) is in the good category. Although the learning environment is in a good category, several points need to be improved so the faculty can increase the quality of the medical education.

Profil Pasien Systemic Lupus Erythematosus Dengan Manifestasi Kardiorespirasi Di Rsud Dr Soetomo Periode Januari - Desember 2018 Dwi Amartya Kirana, Putri; Awalia, Awalia; Hasan, Helmia
Journals of Ners Community Vol 13 No 6 (2022): Journals of Ners Community
Publisher : Fakultas Ilmu Kesehatan Universitas Gresik

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55129/jnerscommunity.v13i6.2760

Systemic Lupus Erythematosus (SLE) merupakan penyakit inflamasi autoimun kronis sistemik dimana sistem kekebalan tubuh menyerang jaringan dan organ tubuh itu sendiri. Penyebab penyakit autoimun ini belum dapat dijelaskan secara pasti. Manifestasi klinis penyakit SLE begitu beragam dan dapat mengenai berbagai organ tubuh. Beberapa manifestasi klinis pada pasien SLE antara lain yaitu adanya kelainan ada paru dan jantung. Penelitian ini bertujuan untuk mengetahui gambaran profil pasien SLE dengan manifestasi kardiorespirasi yang menjalani rawat inap di RSUD Dr.Soetomo Surabaya. Pengambilan sampel dilakukan dengan teknik total sampling yang berarti semua individu pada populasi yang memenuhi kriteria inklusi merupakan sampel. Jenis penelitian yang digunakan dalam penelitian ini adalah deskriptif dengan menggunakan data sekunder berupa rekam medis. Total sampel yang sesuai dengan kriteria inklusi berjumlah 74 pasien. Pasien didominasi oleh perempuan dengan kelompok usia terbanyak adalah usia 26-45 tahun. Sejumlah 22 pasien dilaporkan meninggal dengan penyebab terbanyak adalah syok sepsis. Manifestasi paru yang ditemukan berupa efusi pleura (30.6%), penumonitis lupus (28.6%), pneumonia (27%), edema paru (11.1%), hipertensi pulmonal (6.3%), tuberkulosis (6.3%), ILD (6.3%). Manifestasi jantung yang ditemukan adalah efusi perikardium (46.7%), insufisiensi katup mitral (30%), insufisiensi katup trikuspid (33.3%), insufisiensi katup pulmonal (6.7%), dilated cardiomypathy (6.7%), dan heart failure (13.3%). Kelainan laboratorium yang ditemukan adalah anemia 66.6%, limfopenia 75.3%, trombositopenia 37%. Terapi yang banyak diberikan berupa methylprednisolon, chloroquin, antibiotik ceftriaxone, dan levofloxacin. Pasien SLE dengan manifestasi kardiorespirasi didominasi oleh perempuan usia produktif. Penyebab kematian pada pasien SLE dengan manifetsasi kardiorespirasi terbanyak adalah akibat syok sepsis.

A Study on Predicting High Achievers among Medical Students in the 4th Semester Faculty of Medicine Universitas Airlangga Hermanto Tri Joewono; Herawati, Lilik; Ummah, Fithriyah Cholifatul; Handayani, Samsriyaningsih; Chandra, Cecilia Felicia; Hasan, Helmia; Rejeki, Purwo Sri; Sakina; Heryana, Achmad Yuniari; Kuswandi, Dedi
Asian Journal of Health Research Vol. 4 No. 1 (2025): Volume 4 No 1 (April) 2025
Publisher : Ikatan Dokter Indonesia Wilayah Jawa Timur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55561/ajhr.v4i1.223

Introduction Student-centered learning (SCL) is based on students' needs, capacities, and other characteristics, making the method more personalized. This study aimed to analyze new questionnaires to categorize 4th-semester medical faculty students based on their characteristics. Understanding these characteristics could make the teaching and learning process more effective, potentially reducing the number of students retaking exams. Material and Methods: Subjects were 4th semester students who agreed to enroll and self-fulfilled the questionnaire. High achievers are defined as high expectations and consistent high performance (GPAs). Validity and reliability of each item were analyzed by statistical calculations accordingly. GPA in the next semester was used as threshold to confirm the participant's categorization. Results: The study commenced in March 2022, with 107 participants with Grade Point Averages (GPAs) available. The study demonstrated that the questionnaires had high validity and reliability (p-value < 0.005; Pearson Correlation Coefficient and Cronbach alpha). Among the participants, 3 (2.8%) were classified as high achievers, while 3 (28%) were categorized as low achievers. Notably, 44.86% of participants reported their passions as unrelated to medicine, while 5.61% were uncertain of their passions. Regarding vocation, 8.2% cited parental influence, and 10.3% felt their educational progress was not within their control. Conclusion: The questionnaires had high validity and reliability in item analysis. There were 2,8% of participants predicted as High Achievers and Low Achievers. Refinements of items and score presentation are needed. Follow-up activities should be given to the low achievers to prevent becoming retakers.

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