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All Journal Farmaka Biology, Medicine, & Natural Product Chemistry Majalah Obat Tradisional The Indonesian Biomedical Journal Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Jurnal Penelitian Farmasi Indonesia SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan JOPS (Journal Of Pharmacy and Science) JISIP: Jurnal Ilmu Sosial dan Pendidikan Jurnal Ilmu Kefarmasian Indonesia Jurnal Riset Kefarmasian Indonesia JPK: Jurnal Proteksi Kesehatan Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal Pengabdian Masyarakat Medika Journal of Artificial Intelligence and Digital Business Sinteza Jurnal Farmasi Indonesia Jurnal Pengabdian Masyarakat Borneo Journal of Pharmacy Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Meiriza Djohari, Meiriza
Sekolah Tinggi Ilmu Farmasi Riau
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Potential of Kedabu (Sonneratia ovata Backer) Fruit Juice Supplemented in Kombucha Beverage as Antibacterial Agent Nasution, Musyirna Rahmah; Nabilah, Clara; Djohari, Meiriza; Nurhapipah, Nurhapipah
Biology, Medicine, & Natural Product Chemistry Vol 14, No 1 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.141.453-463

Abstract

Riau Province has abundant natural resources of mangrove forests almost along the coast of Riau. Mangrove fruit can be developed into various processed foods, but processed foods derived from mangroves have not been widely developed and are of interest to coastal communities. Kombucha tea is a probiotic beverage produced through the fermentation of tea and sugar using a kombucha starter known as SCOBY (Symbiotic Culture of Bacteria and Yeast). The presence of sugar in kombucha colonies is a vital source of nutrition. Additionally, fruit juice can be incorporated to create variations of kombucha tea. Kedabu fruit (Sonneratia ovata B.), a native fruit of Riau Province, is recognized for its high carbohydrate content and secondary metabolites, which exhibit potential antibacterial properties. This research developed four formulations of kombucha tea, each with different concentrations of kedabu fruit juice (0%, 10%, 20%, and 30%). The study’s objectives were to formulate, evaluate the physicochemical properties and antibacterial activity of these formulations against Escherichia coli and Staphylococcus aureus. The organoleptic properties, alcohol content, pH, %TTA (Total Acidity Titratable), total LAB (Lactic Acid Bacteria), and yeast count were assessed during a 14-day fermentation period. The assay results indicated that the kombucha fruit kedabu tea formulation exhibited favorable organoleptic characteristics, a decrease in pH, an increase in %TTA, total LAB, and yeast count within the acceptable range defined by standards. Moreover, it displayed inhibitory activity against Escherichia coli and Staphylococcus aureus bacteria, falling within the weak to moderate categories.
PEMBERIAN EDUKASI TENTANG CARA MENGATUR OBAT BAGI LANSIA AGAR TETAP SEHAT SELAMA RAMADHAN DI UPT PSTW HUSNUL KHOTIMAH Djohari, Meiriza; Pratiwi, Erniza; Fadhli, Haiyul; Safitri, Devi; Rifani, Mhd; Putri, Sella Hilmalia Nur Al; Sumbarita, Silvia; Rahmatunnur, Siti; Mardianti, Tengku Shella; Muti’ah, Try Hadirah; Azizah, Wahyu; Zamri, Wiedya Alfitrya; Maqfiroh, Wirdarani
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 7 (2025): BESIRU : Jurnal Pengabdian Masyarakat, Juli 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i7.1574

Abstract

Elderly people who undergo regular drug therapy often face problems in adjusting the time they take medication during fasting. This is due to changes in eating schedules during Ramadan. Some medications may require adjustments in dose, frequency, or even formulation so that they continue to work well. The aim of this service is to increase public understanding, especially the elderly, about how to manage medication schedules and doses during fasting. Service activities are carried out using a demonstration and discussion system by giving brochures to the elderly at UPT PSTW Husnul Khotimah. Starting from filling out the questionnaire sheet (pre-test), distribution of brochures, verbal education and ending with filling out a questionnaire sheet (post-test) related to participants' understanding of the information that has been presented. Based on the results, an increase in the average value was obtained pre-test by 41.25% to 72.16% in post-test, and in statistical tests with Paired Sample Test shows a significance value of 0.000, which indicates there is a significant difference between before and after counseling. So it can be concluded that the counseling carried out at UPT PSTW Husnul Khotimah significantly increased the knowledge of the elderly, especially regarding the use of medication during fasting.
Peningkatan pengetahuan terhadap sosialisasi dagusibu pada siswa SMA An Namiroh kota Pekanbaru Djohari, Meiriza; Susanti, Adriani; Ulfa, Rodhia; Parina, Ana Bella; Putri, Atika; Fadila, Azhariah; Winekas, Bintang Bayu; Setyowati, Bonita Dwi; Adilla, Dea; Amrianis, Delfi; Farahdilla, Dinda; Rizki, Rahmi Asrina; Ikhwani, Ulfha; Sinulingga, Yori Yunita
SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan Vol 8, No 3 (2024): September
Publisher : Universitas Muhammadiyah Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31764/jpmb.v8i3.25929

Abstract

AbstrakIkatan Apoteker Indonesia melakukan edukasi baru yang disebut DAGUSIBU, yang merupakan singkatan dari "Dapatkan, Gunakan, Simpan, dan Buang". Dengan mengikuti langkah-langkah yang diuraikan dalam program DAGUSIBU yang dimulai dengan perolehan obat-obatan dan diakhiri dengan pembuangannya. Salah satu lapisan masyarakat yang sejak dini harus mengetahui tentang penggunaan obat adalah Siswa SMA. Untuk memastikan siswa tidak melakukan kesalahan dalam menggunakan obat, kegiatan sosialisasi DAGUSIBU dilaksanakan karena siswa masih belum memiliki cukup informasi tentang cara menggunakan obat yang benar.  Siswa SMA An Namiroh Kota Pekanbaru mengikuti sosialisasi DAGUSIBU dengan menggunakan kuesioner sebelum dan sesudah tes untuk mengukur pengetahuan mereka. Sebanyak 50 siswa yang mengikuti sosialisasi menunjukkan terjadinya peningkatan pengetahuan yaitu dari 75% pada pretest menjadi 93,4% pada posttest. Hasil menunjukkan bahwa pemahaman siswa terhadap DAGUSIBU dapat meningkat sebesar 18,4% ketika sosialisasi ini diadakan. Kata kunci: dagusibu; pengetahuan; obat. AbstractThe Indonesian Pharmacists Association is conducting a new education program called DAGUSIBU, which stands for “Get, Use, Store, and Dispose”. By following the steps outlined in the DAGUSIBU program that starts with the acquisition of medicines and ends with their disposal. One of the layers of society that should know about the use of medicines from an early age is high school students. To ensure that students do not make mistakes in using medicines, DAGUSIBU socialization activities are carried out because students still do not have enough information about how to use medicines correctly.  Students of An Namiroh High School in Pekanbaru City participated in the DAGUSIBU socialization using pre- and post-test questionnaires to measure their knowledge. A total of 50 students who participated in the socialization showed an increase in knowledge from 75% in the pretest to 93.4% in the posttest. The results show that students' understanding of DAGUSIBU can increase by 18.4% when this socialization is held. Keywords: dagusibu; knowledge, medicine.
PENGARUH PEMBERIAN EKSTRAK ETANOL DAUN TUMBUHAN AKAR KAIK-KAIK (Uncaria cordata (Lour.)Merr) TERHADAP KADAR TRIGLISERIDA SERUM TIKUS PUTIH (Rattus norvegicus) JANTAN Meiriza Djohari; Dwi Pratiwi; Novia Sinata; Noveri Rahmawati
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 9 No. 2 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i2.679

Abstract

Hypertriglyceridemia is a condition when there is an increase in triglyceride levels in the blood. Hypertriglyceridemia can cause heart problems. One of the plants that can be used as medicine is the root plant kaik-kaik (Uncaria cordata (lour.) Merr). This study aims to determine the effect of giving ethanol extract of kaik-kaik (Uncaria cordata (lour.) Merr) leaves on serum triglyceride levels of male white rats (Rattus norvegicus). The parameters used were serum triglyceride levels of male white rats induced by high fat feed, namely quail egg yolk as much as 10 ml/kgBB. This study used 18 male white rats which were divided into 6 groups with 3 rats per group. The normal group was fed only with rats and Na CMC suspension, the negative group was given high-fat feed induction and Na CMC suspension. The positive group was given high-fat feed induction and 0.9 mg/kgBB of atorvastatin suspension. The treatment group was given high-fat feed and a suspension of ethanol extract of kaik-kaik root leaves at doses of 100, 200, and 400 mg/kgBB as much as 1% of body weight given orally. The method used was colorimetric enzymatic using a Mindray® photometer (BA-88A) at a wavelength of 510 nm. Triglyceride level data on days 0, 15, 22 and 29 were analyzed by one-way ANOVA test and repeated ANOVA. The results showed that the ethanol extract of kaik-kaik root (Uncaria cordata (Lour.) Merr) leaves at doses of 100, 200 and 400 mg/kgBB had an effect in reducing serum triglyceride levels of male white rats (Rattus norvegicus) indicated by differences. which was significant (p <0.05) with negative control and showed activity to decrease triglyceride levels which was not significantly different (p> 0.05) with atorvastatin.
ISOLASI DAN UJI AKTIVITAS DAYA HAMBAT EKSTRAK ETANOL BIJI PINANG (Areca catechu L.) TERHADAP BAKTERI PADA LIDAH Djohari, Meiriza; Putri, Wulandari Yulia; Pratiwi, Erniza
Jurnal Riset Kefarmasian Indonesia Vol. 1 No. 3 (2019): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v1i3.57

Abstract

Betel nut (Areca catechu L.) is a natural material that has antibacterial activity in treating diseased on teeth, halitosis and can inhibit of dental caries. The objective of this research is type of bacteria based on morphology, the results of bacterial identification tests on the tongue and to determine the effect of the inhibitory power of betel nut ethanol extract (Areca catechu L.) to bacteria of the tongue. Antibacterial activity testing using disc diffusion method with various concentrations of 10%, 20% and 30%. Secondary metabolite contents are alkaloid, terpenoid and flavonoid.The results obtained from the identification test based on the color of bacteria Branhamella catarrhalis, Staphylococcus epidermidis and Straphylococcus aureus. Ethanol extract of areca nut (Areca catechu L.) is better to inhibiting the growth of Staphylococcus epidermidis and Staphylococcus aureus compared to Branhamella catarrhalis. Based on Two Way Anova statistical data on inhibitory zone diameters, there were differences between the concentration groups of 10%, 20% and 30% and there were significant differences in the inhibitory activity of Branhamella catarrhalis bacteria compared to Staphylococcus epidermidis and Straphylococcus aureus bacteria but not significantly different between Staphylococcus epidermidis and Straphylococcus aureus bacteria
Rheumatoid Artritis, Acute Upper Respiratory Infection Of Multiple and Unspecified Sites, Tension Type Headache, and Hypokalemia Djohari, Meiriza; Sufi, Tengku Yuni Atika; Safitri, Salsa Widya; Nurhasanah, Nurhasanah; Nursyah, Salsabila Putri; Annisa, Refina; Apriella, Weri
RIGGS: Journal of Artificial Intelligence and Digital Business Vol. 5 No. 1 (2026): Februari - April
Publisher : Prodi Bisnis Digital Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/riggs.v5i1.8244

Abstract

Rheumatoid Arthritis (RA) merupakan penyakit autoimun kronik yang ditandai oleh peradangan pada membran sinovial, sehingga menimbulkan nyeri, kekakuan, pembengkakan, dan kerusakan sendi yang bersifat progresif. Penyakit ini tidak hanya menyerang sistem muskuloskeletal, tetapi juga bersifat sistemik dan dapat memengaruhi berbagai organ seperti paru, jantung, dan ginjal. Proses inflamasi kronik yang berlangsung lama, ditambah dengan penggunaan terapi imunosupresif jangka panjang, menyebabkan penurunan fungsi sistem imun. Akibatnya, pasien RA menjadi lebih rentan terhadap berbagai infeksi, termasuk infeksi saluran pernapasan atas (ISPA). ISPA pada pasien RA dapat memperburuk kondisi inflamasi yang sudah ada dan memicu kekambuhan atau flare penyakit melalui peningkatan respons imun sistemik. Selain itu, infeksi akut juga dapat mengganggu metabolisme tubuh serta keseimbangan elektrolit, salah satunya menyebabkan hipokalemia. Kondisi hipokalemia ini berkontribusi terhadap munculnya kelemahan otot, kelelahan, serta gangguan fungsi neuromuskular. Pada beberapa kasus, RA juga berhubungan dengan gangguan fungsi ginjal, seperti renal tubular acidosis distal, yang semakin memperparah ketidakseimbangan elektrolit tersebut. Kombinasi antara RA, ISPA, dan hipokalemia dapat meningkatkan risiko timbulnya gejala lain, seperti tension type headache (TTH). Gejala ini dipicu oleh nyeri kronik, stres sistemik, gangguan tidur, serta kelelahan yang berkepanjangan. Hal ini menunjukkan bahwa RA merupakan penyakit kompleks yang dapat berkembang menjadi kondisi multisistem dengan berbagai komplikasi serius. Oleh karena itu, diperlukan penatalaksanaan yang komprehensif dan berkelanjutan untuk mengendalikan inflamasi, mencegah infeksi, menjaga keseimbangan metabolik, serta meningkatkan kualitas hidup pasien secara optimal dan menyeluruh.
Gambaran Penggunaan Obat Infeksi Saluran Pernapasan Akut (Ispa) Pada Pasien Pediatri Di Puskesmas Sidomulyo Rawat Jalan Kota Pekanbaru Meiriza Djohari; Wira Noviana Suhery; Ewika Pritiya Utami
JURNAL FARMASI DAN MAKANAN Vol 7 No 2 (2024): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i2.3696

Abstract

Infeksi Saluran Pernapasan Akut (ISPA) adalah penyakit infeksi yang menyerang salah satu bagian atau lebih dari saluran napas, mulai dari hidung (saluran atas) hingga alveoli (saluran bawah). Infeksi saluran pernapasan akut adalah infeksi yang disebabkan oleh virus dan bakteri. Penelitian ini bertujuan untuk mengetahui gambaran penggunaan obat infeksi saluran pernapasan akut (ISPA) pada pasien pediatri di puskesmas sidomulyo rawat jalan kota pekanbaru. sampel yang digunakan yaitu data pasien pediatri ISPA puskesmas pada tahun 2021 di Puskesmas Sidomulyo Rawat Jalan Kota Pekanbaru. Metode yang digunakan retrospektif dengan teknik purposive sampling. Berdasarkan hasil penelitian yang di lakukan, di dapatkan hasil penggunaan antihistamin 165 obat (31,79%), ekspektoran 156 obat (30,05%), analgetik 103 obat (19,84%), antibiotik 87 obat (16,76%), mukolitik 5 obat (0,96%), bronkodilator 2 obat (0,38%), dan kortikosteroid 1 obat (0,19%). Berdasarkan zat aktif obat didapatkan, CTM 165 obat (31,79%), guafenesin 156 obat (30,05%), paracetamol 103 obat (19,84%), amoxicillin 83 obat (15,99%), ambroxol 5 obat (0,96%), cefadroksil 3 obat (0,57%), salbutamol 2 obat (0,38%) dan eritromisin 1 obat (0,19%).
PENGARUH PEMBERIAN FRAKSI ETIL ASETAT DAUN TUMBUHAN AKAR KAIK-KAIK (Uncaria cordata (Lour.) Merr.) TERHADAP KADAR Low Density Lipoprotein (LDL) TIKUS PUTIH (Rattus novergicus) JANTAN: The Effect of Giving Ethyl Acetate Fraction of Leaves from Uncaria cordata on Levels of LDL of Male White Rats Meiriza Djohari; Fina Aryani; Haniyah Nabilah
JURNAL FARMASI DAN MAKANAN Vol 8 No 2 (2025): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v8i2.6222

Abstract

Akar Kaik-kaik (Uncaria cordata (Lour.) Merr) can be used as herbal medicine to decrease LDL level in the body. This research aims to determine the effect of ethyl acetate fraction the leaf of akar kaik-kaik (Uncaria cordata (Lour.) Merr) toward LDL level in a male white rat serum (Rattus norvegicus). The measurement method used is Direct Homogeneous Assay using reagents and photometer (Mindray® BA-88A) at a wave length of 578 nm. The results obtained in the form of LDL levels and analyzed using two-way ANOVA. The results showed that the ethyl acetate fraction in the leaves of akar kaik-kaik (Uncaria cordata (Lour.) Merr.) doses of 200 and 400 mg/KgBW kgBW could reduce LDL levels as seen from the significant difference (p<0.05) with the negative control group. and has a comparable effectiveness with atorvastatin seen from the absence of significant differences (p>0.05) with the positive control group.
Gambaran Penggunaan Multivitamin selama Pandemi COVID-19 di Apotek Kota Pekanbaru Fina Aryani; Windi Sayuti Ningsih; Meiriza Djohari; Anugrah Humairah
Sinteza Vol. 4 No. 1 (2024): February
Publisher : Universitas Hamzanwadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29408/sinteza.v4i1.21051

Abstract

Tingginya kasus COVID-19, mengharuskan masyarakat untuk melakukan berbagai upaya preventif atau pencegahan, salah satu upaya yang dapat dilakukan adalah dengan menjaga imunitas tubuh yang dapat ditingkatkan dengan penggunaan multivitamin. Multivitamin mengandung beberapa vitamin dan mineral, kecukupan zat gizi terutama vitamin dan mineral sangat diperlukan dalam mempertahankan sistem kekebalan tubuh yang optimal. Penelitian ini bertujuan untuk mengetahui penggunaan multivitamin pada masyarakat di salah satu apotek Kota Pekanbaru selama pandemi COVID-19. Penelitian ini merupakan penelitian observasional yang bersifat deskriptif dengan teknik pengambilan data secara retrospektif. Populasi pada penelitian ini adalah data semua penjualan multivitamin selama pandemi Covid-19 dari bulan Maret 2020 hingga Juni 2021. Sampel adalah semua populasi sehingga teknik pengambilan sampel yang digunakan yaitu sampel jenuh. Data yang diambil adalah data sekunder berupa data penjualan multivitamin selama pandemi Covid-19 dari bulan Maret 2020 hingga Juni 2021. Hasil penelitian menunjukkan bahwa penjualan nama multivitamin yang paling banyak adalah Zegavit® sebanyak 10,41% dengan zat aktif Vitamin C sebesar 45,40%, bentuk sediaan multivitamin yang paling banyak terjual adalah tablet atau kaplet dengan persentase 68,16% dengan komposisi kombinasi sebesar 98,42%. Berdasarkan hasil penelitian disimpulkan multivitamin yang paling tinggi angka penjualannya yaitu multivitamin kombinasi dengan bentuk sediaan tablet.
Co-Authors Achdar, Ridza Fitria Adelina, Helmi Rahmah Adilla, Dea Adriani Susanty Afridho, Arif agistia, nesa Alifah Nurul Khusnah Amalia, Annisa Yuri Amrianis, Delfi Andi Wijaya Annisa Safitri Annisa, Refina Anugrah Humairah Apriella, Weri Armon Fernando Ayu Indah Lestari Afandi Azizah, Wahyu Belia Sonali Bendre Burhanuddin Bahar Cahyani, Astri Dea Adilla Deni Anggraini Devi Safitri DEWI FITRIANI Dewi, Irana Dinda Zulfi Rosadi Diova Yuswidia Putra Dwi Pratiwi Enda Mora Ewika Pritiya Utami Fadhila, Metha Fadhila, Qonita Nur Fadila, Azhariah Farahdilla, Dinda Fina Aryani Fina Aryani, Fina Haiyul Fadhli Haniyah Nabilah Hasanah, Mitha Humairah, Anugrah Husnawati Husnawati Husnawati Husnawati Ikhwani, Ulfha Karismawati, Karismawati Kuang, Liau Che Linda, Rosa Mansyur Arif Mansyur Arif Maqfiroh, Wirdarani Mardianti, Tengku Shella Melisa, Eva Melzi Octaviani Mira Febrina Musyirna Rahmah Nst Muti’ah, Try Hadirah Nabilah, Clara Neni Frimayanti Nofri Hendri Sandi Noveri Rahmawati Nur Indah Melati Nurhapipah, Nurhapipah Nurhasanah Nurhasanah Nursyah, Salsabila Putri Parina, Ana Bella Pratiwi, Erniza Putri, Atika Putri, Bayzola Ditya Putri, Sella Hilmalia Nur Al Putri, Widia Rahma Putri, Wulandari Yulia Rahmatunnur, Siti Rahmi, Yuni Rifani, Mhd Rina Lestari Rizki, Rahmi Asrina Rodhia Ulfa Rovi Paramitha, Rovi Rustam, Muhanifa Safitri, Salsa Widya Septi Muharni Setyowati, Bonita Dwi Sinata, Novia Sinulingga, Yori Yunita Sisca, Sari Kurnia Sufi, Tengku Yuni Atika Sulastri Sumbarita, Silvia Suryani As&#039;ad Susanti, Adriani Syilfia Hasti Tania Tiara Efendi Tania, Berla Tri Wahyuni Winda Yusma Ameliah Windi Sayuti Ningsih Winekas, Bintang Bayu Wira Noviana Suhery Yuni Rahmi Yuti, Denisyah Fitri Zamri, Wiedya Alfitrya