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Journal : JURNAL KIMIA SAINS DAN APLIKASI

Antimicrobial Activities of Synthesized Silver Nanoparticles using Ethanol and Water Extract of Mirabilis Jalapa Tunas Alam; Frida Octavia Purnomo; Asbar Tanjung
Jurnal Kimia Sains dan Aplikasi Vol 24, No 3 (2021): Volume 24 Issue 3 Year 2021
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (3116.302 KB) | DOI: 10.14710/jksa.24.3.70-76

Abstract

The focus of this study was to compare the antimicrobial activity of silver nanoparticles (AgNPs) synthesized using ethanol extracts (AgNPE) and water extracts (AgNPA) from four o’clock flowers (Mirabilis jalapa) against Staphylococcus aureus. AgNPs were characterized by UV-Vis diffraction, FTIR, SEM, and X-rays. UV-Vis analysis showed that AgNPA has an SPR band of about 460 nm and 530 nm for AgNPE, which proves the characteristics of the absorbance area of AgNPs. SEM images of AgNPE and AgNPA show a cuboid shape with a mean diameter of 80 and 30 nm, respectively and well dispersed. The response to the presence of polysaccharide biomolecules involved in forming AgNPs was analyzed using a Fourier transform infrared spectrometer. The result was that AgNPA and AgNPE have different reducing agents. The plant extracts, AgNPE and AgNPA, were studied for their antimicrobial activity against Staphylococcus aureus. The result was that both AgNPA and AgNPE showed good activity and showed that AgNPA with less inhibition was more effective than AgNPE.
Tyrosinase Inhibitory of Silver Nanoparticles Synthesized using Morus Nigra Leaves Extract Tunas Alam; Ricky Ardiansyah; Sharfina Maulidayanti; Deva Azvara; Frida Octavia Purnomo; Dicky Annas
Jurnal Kimia Sains dan Aplikasi Vol 26, No 3 (2023): Volume 26 Issue 3 Year 2023
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.26.3.85-90

Abstract

A novel preparation of silver nanoparticles using Morus nigra leaves extract, as opposed to the physical and chemical methods had been used in this work. Their active phytochemical compounds will reduce Ag+ and form AgNPs (Ag0). A peak spectrum at 460 nm was formed and confirmed as the Surface Plasmon Resonance (SPR). Vibration at 1643 cm-1 and 3286 cm-1 which characteristic of C=C bonds and (-OH) hydroxyl groups, respectively. An X-ray diffraction (XRD) examination of silver with good crystallinity revealed its distinctive pattern. According to the results of transmission electron microscopy (TEM), the produced AgNPs-Morus nigra leaves extract were between 10 and 20 nm in size. Using L-dihydroxyphenylalanine (L-DOPA) as the substrate, the synthesized AgNPs-Morus nigra were tested for their tyrosinase inhibitory activity, and the results are substantial when compared to kojic acid as a control. The percentages of inhibition from crude extract, AgNPs, and kojic acid at 100 µg/mL are to be found at 12.10 %, 64.80 %, and 59.84 %, respectively. Based on the results of this work, AgNPs can be produced by utilizing a green synthesis method with leaves extract, making them a promising candidate for use in medicine and cosmetics.
Co-Authors Adinda Nur Syahfira Adiningsih, Septia Nur Wahyu Alam, Tunas Alisa Kholisah Ananta, Natasia Okny Astri Anjarini, Niluh Devi Arifianto, Zahwaza Azriellya Asbar Tanjung Ayu Ardhyani Pratiwi Azzahroh, Putry Mauzen Bunga Destyana Chindi Maria Marbun Christofer, Nicholas Desi Aryani Destiyana, Bunga Deva Azvara Dian Rachma Wijayanti Dicky Annas Dina Fitriana Diren Handayani Dwi Puspita Sari, Dwi Puspita Dyah Ayuwati Waluyo Efendy, Vina Era Susanti Febriana, Sella Febriyanti, Dina Friscila, Friscila Habibillah, Yolanda Rahmah Halimatushadyah, Ernie Hanan, Raihan Arung Hartono, Olyvia Azzahra Putri Hawa, Adinda Siti Humaedi, Aji Ila Rosilawati Intan Permata Sari K , Vonny Lestari Kartika Rahma Kartika Rahma Khuzaimah Farradilla Mutaqin Komariah Kamerinda, Siti Krismayadi Krismayadi Kurniawan, Naufel Hafidz Lala Ananda Oktavia Larasati, Dewi Adelia Lestari, Puspa Ayuningdyah Lisa Tania Lubis, Faisal Lukitasari, Nurraya Madiabu, Mohammad Jihad Margareta, Siska Marvel Hamonangan Masyha, Dilea Dara Mimah Mulhimah Muhamad Shadam Gusbian Muhammad Syaiful Kahfi Mulyani, Hanny Dwicahya Mutia Sari Wardana Nabilah Istiyani Nabilah Istiyani Ningrum, Sari Sekar Novitasari, Anggraeni Nur Anisa, Sarfina Nusantarawati, Eka oktavelani, Oktavelani Tiara Eka Putri Oktaviana, Putri Olyvia Azzahra Orlinka, Kenvi Paramyta, Bunga Destiyana Pramesti, Anggi Shiva Prayoga, Andoscha Penyulas Putri Dewanti, Shafira Putri, Azkharien Meydiana Putri, Yulia Anggraeni Putry Mauzen Qonita, Vira Rahmawati, Icha Ramawati, Dini Ratnayani Realmis Pujani Gulo Ricky Ardiansyah Ritonga, Ahmad Fitra Sadwika Najmi Kautsari Sharfina Maulidayanti Simbolon, Clara Bella Suparlan Hadi Surgawati, Surgawati Syafitri, Mulyani Syafrima Wahyu Syahdilia, Nella Syarobhi, Muhammad Wildan Tambun, Romauli Tarisya Anilya Dwi Putri Tesha Sari Angrainy Rodesia Tsabitah, Nadiah Tunas Alam Widiyawati, Dwi Wiranti, Dinar Septia Yuhanda, Farhan Naufal Yuliana, Agnes Zahrani, Kaila Sifa