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All Journal Pharmascience Jurnal Surya Medika Jukung (Jurnal Teknik Lingkungan) Al-Ard: Jurnal Teknik Lingkungan Jurnal Sehat Mandiri Jurnal Politikom Indonesiana PREPOTIF : Jurnal Kesehatan Masyarakat HSG (Health Science Growth) Journal Jurnal Integrasi Kesehatan dan Sains Indonesian Journal of Community and Special Needs Education (IJCSNE) Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Journal of Sustainable Community Service Journal of Pharmaceutical and Sciences. ASEAN Journal for Science and Engineering in Materials Preventif : Jurnal Kesehatan Masyarakat
Sudarjat, Hadi
Universitas Singaperbangsa Karawang
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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PREFERENSI KLINIS PEMILIHAN CETIRIZINE ATAU HLORPHENIRAMINE MALEAT DALAM PENGOBATAN ALERGI Shadrina, Jahra Almas; Hilmi , Indah Laily; Sudarjat, Hadi; Affandhy, Adhwa’a Kaylla; Dzannuba, Fadya Laila
PREPOTIF : JURNAL KESEHATAN MASYARAKAT Vol. 8 No. 3 (2024): DESEMBER 2024
Publisher : Universitas Pahlawan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/prepotif.v8i3.37749

Abstract

Alergi adalah gangguan inflamasi kronis dengan reaksi kekebalan yang menyimpang terhadap bahan kimia lingkungan tertentu, yang disebut alergen. Antihistamin  seperti cetirizine dan chlorpheniramine maleat sering diresepkan untuk menangani alergi. Meskipun sama-sama merupakan antihistamin , keduanya memiliki perbedaan penting dalam hal efektivitas, profil efek samping, dan keamanan. Artikel review ini bertujuan untuk mengetahui frekuensi penggunaan cetirizine dan chlorpheniramine maleat di fasilitas kesehatan serta mengidentifikasi alasan di balik pemilihan masing-masing obat dalam pengobatan alergi. Metode yang digunakan adalah narrative review, dengan populasi pasien yang mengalami alergi dan memerlukan pengobatan dengan antihistamin  di suatu fasilitas pelayanan kesehatan dengan intervensi penggunaan cetirizine sebagai pilihan antihistamin  untuk mengatasi alergi dengan perbandingan penggunaan chlorpheniramine maleat sehingga diperoleh pemahaman mengenai preferensi klinis dalam memilih cetirizine atau chlorpheniramine maleat. Literatur diperoleh dari Google Scholar dan Publish or Perish, diikuti analisis bibliometrik menggunakan perangkat lunak VOSviewer. Hasil dari 13 jurnal yang diperoleh menunjukkan bahwa cetirizine lebih sering digunakan dibandingkan chlorpheniramine maleat. Efek sedasi yang rendah dan durasi kerja yang lebih lama (hingga 24 jam), menjadikan cetirizine pilihan lini pertama. Chlorpheniramine maleat, meskipun memiliki efek sedasi yang tinggi dan durasi kerja yang lebih singkat (4-6 jam), tetap digunakan dalam situasi tertentu karena harganya lebih terjangkau dan lebih mudah didapat.
Literature Review: Strategi Konseling Efektif untuk Meningkatkan Kesadaran Pasien Hipertensi terhadap Risiko dan Manajemen Penyakit di Indonesia Nisa, Nasywa Khoirun; Hilm, Inda Laily; Sudarjat, Hadi
Jurnal Integrasi Kesehatan dan Sains Vol 7, No 1 (2025): Jurnal Integrasi Kesehatan dan Sains (in progress)
Publisher : Universitas Islam Bandung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jiks.v7i1.14398

Abstract

Hipertensi adalah kondisi saat tekanan darah mencapai ≥140 mmHg atau ≥90 mmHg. Kondisi ini dapat memburuk tanpa gejala hingga mengancam nyawa sehingga konseling yang efektif diperlukan untuk meningkatkan kesadaran pasien tentang risikonya. Tujuan artikel ini adalah mengidentifikasi praktik konseling yang paling efektif untuk penyakit hipertensi dan menganalisis efektivitas strategi konseling dalam meningkatkan kesadaran pasien. Penelitian ini merupakan literature review, dengan sampel yang berasal dari database. Database yang digunakan pada penelitian ini adalah Google Scholar dengan bantuan perangkat lunak Publish or Perish dan kata kunci "Media", "Konseling", dan "Hipertensi". Jumlah artikel yang diperoleh sebanyak 977 artikel. Skrining dilakukan menggunakan metode kriteria inklusi PICO framework. Hasil skrining menunjukkan terdapat 11 artikel yang sesuai dengan kriteria inklusi, sementara artikel yang dikeluarkan berdasarkan kriteria eksklusi sebanyak 966 artikel. Kriteria PICO dalam penelitian ini meliputi: populasi (penelitian yang membahas konseling penyakit hipertensi), intervensi (penelitian yang menggunakan suatu media untuk konseling hipertensi), perbandingan (penelitian yang mencantumkan data kuantitatif sebagai pembanding), luaran (peningkatan pada kepatuhan pasien), dan studi literatur yang diterbitkan dalam 10 tahun terakhir (2014–2024) dengan nama jurnal serta metode konseling hipertensi yang diterapkan di Indonesia. Dari analisis tersebut diperoleh 11 artikel. Data dianalisis menggunakan analisis bibliometrik dan divisualisasikan menggunakan perangkat lunak VOSviewer untuk menggambarkan perkembangan topik penelitian. Hasil analisis dari 11 artikel yang telah di-review menunjukkan bahwa media konseling seperti leaflet, booklet, poster, video, dan intervensi lainnya berdampak positif pada kepatuhan pasien hipertensi dalam mengonsumsi obat dan menurunkan tekanan darah. Leaflet meningkatkan efikasi diri meskipun tidak signifikan secara statistik. Booklet meningkatkan cakupan secara signifikan dari 60% menjadi 65%. Poster, video, kartu pengobatan, dan aplikasi AMINO terbukti efektif dengan nilai-p < 0,05. SMS dan buku harian juga memberikan dampak positif. Simpulan, booklet meningkatkan cakupan, sedangkan poster, video, kartu pengobatan, dan aplikasi AMINO efektif. Literature Review: Effective Counseling Strategies to Increase Hypertension Patients' Awareness of Risk and Disease Management in IndonesiaAbstractHypertension is a condition in which blood pressure reaches ≥140 mmHg or ≥90 mmHg. This condition can worsen without symptoms to life-threatening levels, so effective counseling is needed to increase patient awareness of the risks. This article aims to identify the most effective counseling practices for hypertensive disease and analyze the effectiveness of counseling strategies in increasing patient awareness. This study is a literature review, with samples obtained from the database. The database used in this study is Google Scholar, which has the help of Publish or Perish software and the keywords "Media," "Counseling," and "Hypertension." A total of 977 articles were obtained. The screening was carried out using the PICO framework inclusion criteria method. The screening results showed that 11 articles met the inclusion criteria, while 966 were excluded. The PICO criteria in this study include population (research that discusses hypertension counseling), intervention (research that uses a medium for hypertension counseling), comparison (research that provides quantitative data as a comparison), outcome (an increase in patient compliance results), and literature published in the last 10 years (2014–2024) with the journal name and hypertension counseling methods applied in Indonesia. Eleven articles were selected for analysis. Data were analyzed using bibliometric analysis and visualized using VOSviewer software to describe the development of research topics. The study of the 11 reviewed articles showed that counseling media such as leaflets, booklets, posters, videos, and other interventions positively impacted hypertension patients' adherence to medication and lowered blood pressure. Leaflets improved self-efficacy, although not statistically significant. Booklets significantly increased coverage from 60% to 65%. Posters, videos, medication cards, and the AMINO app proved effective, with a p-value < 0.05. SMS and diaries also had a positive impact. In conclusion, booklets increased coverage, while posters, videos, treatment cards, and the AMINO app were effective.
Efektivitas Produk Herbal Antijamur untuk Terapi Ketombe (Pityarisis capitis): Literature Review dan Analisis Bibliometrik Syahrin, Esti; Sudarjat, Hadi; Balapadang, Rachel Noveriachristie
Jurnal Sehat Mandiri Vol 20 No 1 (2025): Jurnal Sehat Mandiri, Volume 20 Nomor 1 Juni 2025
Publisher : Poltekkes Kemenkes Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33761/jsm.v20i1.1802

Abstract

Dandruff (Pityriasis capitis) is a skin health problem caused by fungal growth on the scalp, increased production of oil glands (sebum) excessively. Current advances in science and technology have led to the development of herbal plant research to be used as antifungal herbal products in overcoming dandruff. The purpose of this literature review is to review and summarize herbal plants that have the potential to inhibit the growth of fungi that cause dandruff, so that it is useful to be developed as further research. Article searches were conducted from February to May 2024 using the Publish or Perish reference manager (PoP) tool in the Google scholar database source which was then term mapped in the Vosviewer software. The results of original research journal publications related to dandruff published in the range of 2014 to 2024 were obtained as many as 12 journals. The conclusion obtained in this literature review is that secondary metabolite compounds contained in herbal plants have a potential fungal inhibition mechanism, so it is appropriate to be developed in future research and used as an antifungal herbal product to treat dandruff.
Analisis Rhodamin B pada Kerupuk Seblak Prasmanan di Sekitar Universitas Singaperbangsa Karawang Kampus 1 Advaita, Chalisya Vanya; Mierza, Vriezka; Sudarjat, Hadi
Jurnal Pharmascience Vol 12, No 1 (2025): Jurnal Pharmascience
Publisher : Program Studi Farmasi FMIPA Universitas Lambung Mangkurat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20527/jps.v12i1.19358

Abstract

Rhodamin B merupakan pewarna yang tidak boleh digunakan sebagai bahan tambahan pangan (BTP).  Konsumsi Rhodamin B dapat menimbulkan efek racun, gangguan fungsi organ hingga kanker. Seblak prasmanan merupakan seblak dengan variasi kerupuk berwarna. Penelitian ini bertujuan untuk mengidentifkasi Rhodamin B pada kerupuk seblak prasmanan yang dijual di sekitar Universitas Singaperbangsa Karawang kampus 1. Analisis kualitatif dan kuantitatif pada penelitian ini menggunakan metode KLT dengan eluen N-butanol, etil asetat dan ammonia 10% (10:4:5) dan spektrofotometri UV-Vis dengan diawali validasi metode. Hasil uji kualitatif menunjukkan 1 dari 12 sampel positif mengandung Rhodamin B dengan nilai Rf 0,94 dan nilai Rf baku Rhodamin B 0,80. Hasil uji validasi menunjukkan bahwa metode ini baik untuk mengidentifikasi Rhodamin B pada kerupuk dengan nilai parameter korelasi (r) = 0,9999; LOQ 0,2748 mg/L; LOD 0,0842 mg/L; %RSD 0,233%; % recovery 114,725% (konsentrasi 4 mg/L), 108,76% (konsentrasi 5 mg/L) dan 100,117% (konsentrasi 6 mg/L). Berdasarkan hasil analisis diketahui 12 sampel positif mengandung Rhodamin B dengan % kadar (b/b) yang relatif kecil yaitu 0,000476% (A1); 0,000883% (B1); 0,00126% (C1); 0,000277% (A2); 0,00045% (B2); 0,00069% (C2); 0,000577% (A3); 0,0013% (B3); 0,001141% (C3); 0,000377% (A4); 0,000347% (B4) dan 0,00142% (C4).
Literature Review: Efektivitas dan Efek Samping PCSK9 Inhibitor (Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitor) dengan Golongan Statin pada Pasien Penderita Kolesterol Affandhy, Adhwa'a Kaylla; Sudarjat, Hadi; Hilmi, Indah Laily; Shadrina, Jahra Almas; Dzannuba, Fadya Laila Dzannuba Laila
Jurnal Sehat Mandiri Vol 20 No 1 (2025): Jurnal Sehat Mandiri, Volume 20 Nomor 1 Juni 2025
Publisher : Poltekkes Kemenkes Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33761/jsm.v20i1.1746

Abstract

Cholesterol is an essential molecule in the human body, but excessive levels can lead to various diseases, including hypercholesterolemia. The management of high cholesterol involves the use of statins and PCSK9 inhibitors. This study aims to compare the effectiveness and side effects of these two drug classes.This study is a literature review conducted from August to September using articles from the PubMed database with keywords related to PCSK9 inhibitors and statins. The data were analyzed through bibliometric analysis using VOSviewer software with keywords such as PCSK9 inhibitor, alirocumab, bococizumab, and evolocumab.The results showed that PCSK9 inhibitors could reduce LDL-C levels by 57-61% with a good safety profile, although side effects such as injection site reactions were observed. In comparison, statins reduced LDL-C levels by 18-55% and increased HDL-C levels by up to 15%, but their side effects included muscle disorders and liver function impairment. PCSK9 inhibitors provide an additional solution for patients who do not respond optimally to statins. Conclusion: PCSK9 inhibitors are effective in lowering LDL-C in patients who have difficulty achieving target levels with statin therapy alone.
Teaching concept of bio-battery material: Use of Sweet Potato Peels and Lime Juice Solution Maulida, Rahma; Daffa, Muhammad Naufal; Nadhira, Shafwa Faza; Hotimah, Alin Parliana; Anggraeni, Sri; Nandiyanto, Asep Bayu Dani; Sudarjat, Hadi
ASEAN Journal for Science and Engineering in Materials Vol 1, No 2 (2022): AJSEM: Volume 1, Issue 2, September 2022
Publisher : Bumi Publikasi Nusantara

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Wasted sweet potato peel waste is a classic problem in Indonesia, therefore the use of sweet potato peel as biomass for bio-battery production can be used as a solution to this problem. This study aimed to determine the benefits of sweet potato peels and orange solution as biomass for bio-battery production. The main novelties in this study are (1) Used sweet potato peels as bio-battery Material that have never been used in previous studies. (2) Used sweet potato peel as fixed variable and lime juice as independent variable, and (3) Tested the sweet potato peel and lime juice pasta into the clock. This method is done by smoothing the skin of the sweet potato with the addition of 40 mL of lime solution to form a paste. The lime solution used in this study was 0; 5; 10; 15%. Then measure the voltage of the bio-battery and test the wall clock with the bio-battery. The experimental results showed that the sweet potato peel paste with a lime solution produced the same voltage as an ordinary battery at a concentration of 10% with a value of 1.47 V. The bio-battery with the highest concentration variation is not necessarily the best, that's because the pH value affects the current and voltage. The conclusion of this research is that sweet potato peel and lime solution can be used as electrolytes in bio-battery production with optimal variation of 5 and 10%. This study demonstrates the utilization of sweet potato peel waste as an alternative biomass for bio-battery production.
Literatur Review: Efektivitas Konseling Farmasis Terhadap Kepatuhan Minum Obat pada Diabetes Melitus Tipe 2: Literature Review: Effectiveness of Pharmacist Counseling on Compliance with Taking Medication in Diabetes Mellitus Type 2 Nurdin, Fitri Oktaviani; Hilmi, Indah Laily; Sudarjat, Hadi; Yulianti Surasa, Triana Maudy
Jurnal Surya Medika (JSM) Vol. 11 No. 1 (2025): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v11i2.9723

Abstract

Diabetes Melitus (DM) tipe 2 merupakan penyakit metabolik kronis yang memerlukan pengobatan seumur hidup. Salah satu faktor yang memengaruhi keberhasilan terapi DM adalah tingkat kepatuhan pasien terhadap pengobatan. Ketidakpatuhan ini sering kali disebabkan oleh kurangnya pemahaman pasien tentang pentingnya pengobatan jangka panjang. Tujuan: mengevaluasi efektivitas konseling farmasis dalam meningkatkan kepatuhan penggunaan obat pada pasien diabetes mellitus tipe 2. Metode yang digunakan adalah narrative review terhadap artikel yang membahas dampak konseling terhadap kepatuhan pasien. Hasil: Analisis 10 artikel memperlihatkan konseling oleh farmasis secara signifikan meningkatkan kepatuhan pengobatan, menurunkan kadar gula darah, serta memperbaiki hasil klinis secara keseluruhan. Kesimpulan: konseling farmasis merupakan intervensi yang efektif dalam meningkatkan kepatuhan pengobatan dan kontrol glukosa darah, yang berpotensi meningkatkan kualitas hidup pasien diabetes.
Review Article: Analisis Faktor Psikososial yang Memengaruhi Kepatuhan Terapi Antiretroviral pada Penderita HIV/AIDS: Review Article: Analysis of Psyhosocial Factors Influencing Adherence to Antriretroviral Therapy in People with HIV/AIDS Fadilah, Oca Nur; Sholih, Mally Ghinan; Sudarjat, Hadi
Jurnal Surya Medika (JSM) Vol. 11 No. 1 (2025): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v11i2.9758

Abstract

HIV/AIDS melemahkan sistem kekebalan tubuh dengan menghancurkan sel CD4+, sehingga tubuh menjadi rentan terhadap infeksi. Terapi Antiretroviral (ARV) melibatkan kombinasi obat yang harus dikonsumsi seumur hidup dengan tingkat kepatuhan tinggi (>95%) agar efektif. Pada tahun 2022, diperkirakan 1-1,7 juta orang tertular HIV, dan sekitar 480.000-880.000 meninggal akibat HIV; di Indonesia, lebih dari 500.000 kasus HIV dilaporkan pada 2023. Penelitian ini menganalisis faktor-faktor psikosial yang memengaruhi kepatuhan ARV pada pasien HIV/AIDS lewat tinjauan literatur pada artikel yang dipublikasikan antara 2017 hingga 2024 di database Google Scholar, BMC, dan PubMed. Dari 12 artikel yang relevan, ditemukan bahwa dukungan seperti keluarga dan sosial berperan penting dalam meningkatkan kepatuhan, mengurangi stigma, dan memperbaiki mutu hidup Orang dengan HIV/AIDS (ODHA). Dukungan psikososial membantu pasien menjalani terapi dengan konsisten serta mengatasi stigma yang dapat menghambat pengobatan.
Analysis of the Side Effects of Long-Term Proton Pump Inhibitor (PPI) Use in Patients with Gastroesophageal Reflux Disease (GERD) Nurhafidah, Zahra; Hilmi, Indah Laily; Sudarjat, Hadi
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1628

Abstract

Background: Proton Pump Inhibitors (PPIs) are widely prescribed to manage gastrointestinal disorders, especially gastroesophageal reflux disease (GERD). However, long-term PPI use has been linked to serious side effects and potential complications. Objective: This study aims to analyze the side effects associated with prolonged PPI use in patients with GERD. Methods: A systematic review was conducted using Google Scholar and PubMed databases with relevant keywords. Article selection was carried out carefully based on inclusion and exclusion criteria to ensure the quality and relevance of the data. Additionally, a bibliometric analysis was performed to explore research trends related to the long-term use of PPIs. Results: The review found that prolonged PPI use is associated with various adverse effects, including an increased risk of dementia, progression of chronic kidney disease (CKD), gastric cancer, bone fractures, Frailty Syndrome, hypomagnesemia, iron deficiency, vitamin B12 deficiency, myocardial infarction, and esophageal cancer. The bibliometric analysis also indicated a growing trend of research focusing on the safety and complications of long-term PPI use. Conclusion: Long-term PPI therapy carries significant risks. Therefore, regular monitoring and appropriate discontinuation strategies are essential when using PPIs over extended periods to minimize potential harm.
Effectiveness of Clinical Pharmacy Interventions in Medication Adherence for Geriatric Patients: Literature Review Ilham, Febrian Dzikri; Hilmi, Indah Laily; Sudarjat, Hadi
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1654

Abstract

Background: Medication adherence in geriatric patients is a major challenge as polypharmacy increases the risk of drug-related problems (DRPs). The role of clinical pharmacy is important in addressing these issues through evidence-based approaches. Objective: To review the effectiveness of various clinical pharmacy interventions in improving medication adherence in geriatric patients. Methods: This article used a systematic review of 13 literature selected from 934 articles based on inclusion criteria in the last 10 years, using PubMed and Google Scholar databases. The focus of the analysis included education, monitoring, and the use of tools such as pill cards and medication reminder charts. Results: Clinical pharmacy interventions, such as the use of Beers and STOPP/START criteria, counseling, and educational programs using tools, were shown to improve adherence in geriatric patients. Programs such as pill boxes increased adherence by 83.33%. However, some tools such as medication reminder charts had limited effectiveness. Conclusion: A collaborative approach, including patient and family education, monitoring, and clinical criteria-based therapy adjustments, is essential to improve medication adherence in geriatric patients, which directly improves their quality of life.
Co-Authors Advaita, Chalisya Vanya Affandhy, Adhwa'a Kaylla Affandhy, Adhwa’a Kaylla Ahsanal Kasasiah Asep Bayu Dani Nandiyanto Aulia Fashanah Hadining Aulia Hadining Balapadang, Rachel Noveriachristie Daffa, Muhammad Naufal Dzannuba, Fadya Laila Dzannuba, Fadya Laila Dzannuba Laila Fadilah, Oca Nur Gina Lova Sari Gun Gun Gumilar Hadining, Aulia Hermawan, Deri Hilm, Inda Laily Hilmi , Indah Laily Hotimah, Alin Parliana Ilham, Febrian Dzikri Indah Laily Hilmi Kusnadi Kusnadi, Kusnadi Lely Sulfiani Saula Linda Riski Sefrina Mally G Sholih Mally G. Sholih Mally Ghinan Sholih Mayasari Mayasari Mierza, Vriezka Munir Alinu Mulki Nadhira, Shafwa Faza Nisa, Nasywa Khoirun Nurdin, Fitri Oktaviani Nurhafidah, Zahra Rahma Maulida, Rahma Roudotul Jannah Salman Salman Shadrina, Jahra Almas Sholih, Mally Ghinan Sri Anggraeni Syahrin, Esti Tresna, Muhammad Raka Wardani, Aulia Yulianti Surasa, Triana Maudy