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Edukasi Manfaat Tanaman Piperaceae dan Pelatihan Pembuatan Hand Sanitizer Alami kepada Siswa SMK Farmasi Surabaya Meyke Herina Syafitri; Mercyska Suryandari; M.A. Hanny Ferry Fernanda
Nusantara: Jurnal Pengabdian kepada Masyarakat Vol. 3 No. 2 (2023): Mei : Jurnal Pengabdian Kepada Masyarakat
Publisher : Pusat Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/nusantara.v3i2.1226

Abstract

Betel leaves contain phenols that function as powerful antiseptics. Hand sanitizer (HS) is a product that can kill parasites on the hands and is easy to use. Therefore, in this event, education will be provided to the students of SMK Farmasi Surabaya regarding the benefits of betel leaves, followed by a training session on making hand sanitizers containing extract. The participant's level of understanding is evaluated by comparing the scores obtained before and after receiving information from the speaker. A questionnaire is given to allow participants to evaluate the overall conduct of the event, and they are invited to try the hand sanitizers prepared by the team. The results show that 76% of the participants achieved higher scores, 24% maintained the same scores, and none of the participants received lower scores compared to the pre-test. Overall, the participants expressed that the event was very beneficial.
Fraksinasi dan Identifikasi Ektrak Daun Mitragyna Speciosa Menggunakan Metode Kromatografi Fernanda, M.A. Hanny Ferry; Suryandari, Mercyska; Sudarwati, Tri Puji Lestari
FARMASIS: Jurnal Sains Farmasi Vol 2 No 2 (2021): Farmasis : Jurnal Sains Farmasi
Publisher : Universitas PGRI Adi Buana, Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v2i2.4072

Abstract

Background: Mitragyna Speciosa or better known as Kratom is a typical plant from the Putusibau area, West Kalimantan. The most widely used part of this plant is the leaves. The kratom plant contains alkaloids, flavonoids, phenols, terpenoids-steroids, triterpenoids, saponins, and tannins. Alkaloid content is the most dominant and has benefits in this plant so it is necessary to do fractionation and identification of secondary metabolites. Objective: To fractionate and identify secondary metabolites from Mitragyna Speciosa leaf extract. Methods: The fractionation method was carried out using Column Chromatography while for identification using Thin Layer Chromatography. Results: 80 fractions were obtained from the column chromatography results, while the results of identification using thin layer chromatography showed that only the 2nd and 3rd fractions were obtained. The second fraction has two spots with Rf values of 0.51 and 0.73 and in the third fraction there are three spots with Rf values of 0.21; 0.52, and 0.74. Conclusion: Fractionation and identification by chromatographic method can be used as initial screening for secondary metabolite content in Mitragyna Speciosa leaf extract.
DETERMINATION OF TOTAL PHENOL CONTENT IN METHANOL EXTRACT OF ROSEMARY (Rosmarinus officinalis L.) LEAVES BY DIGETION METHODS USING UV-VIS SPECTROFOTOMETRY METHODS Mercyska Suryandari, Mercyska; Dwi Rahayu, Risma; Syafika Rani, Noor
SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Vol. 3 No. 2 (2024): SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Publisher : LPPM Akademi Farmasi Imam Bonjol Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62018/sitawa.v3i2.94

Abstract

The methanol extract of resemary leaves contains terpenoids, alkanoids, flavonoids, tannins, steroids, saponins and polyphenols. The aim of this research was to determine the total phenol of methanol extract of rosemary (Rosmarinus officinalis L.) by digestion method using the UV-Vis spectrophotometric method. In this study, methanol extract of rosemary leaves extracted using the digestion method was used as a sample and gallic acid as a standard. A standard solution of 200 ppm gallic acid was prepared to determine the operating time at 100 minutes and the maximum wavelength at 747 nm. Next, a comparison solution of gallic acid was made with a concentration range of 100, 125, 150, 175, 200 ppm and produced a linear regression equation, namely y = 0.0039× - 0.1146 with a correlation coefficient (r) of 0.9842. Determination of total phenol content was replicated 3 times and the absorption value was observed. The research results showed that the average total phenol content was 57.0317 mgGAE/g extract.
PHYTOCHEMICAL SCREENING OF ETHANOL EXTRACT 96% BLACK EAR MUSHROOM (Auricularia nigricans) BY SOXLETATION METHOD Mercyska Suryandari, Mercyska; Andhika Dwi Aristyawan, Andika; Fiska Yuliarni, Floreta; Ari Anggraini, Nony
SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Vol. 3 No. 2 (2024): SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Publisher : LPPM Akademi Farmasi Imam Bonjol Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Black ear mushroom (Auricularia nigricans) contains useful compounds, traditionally used as medicinal ingredients and food sources. The purpose of this study was to determine the secondary metabolites are contained in the extract of black ear mushroom (Auricularia nigricans). The extraction method used in this study is soxletation method. The sample used is 200 g of black ear mushroom (Auricularia nigricans) was extracted using soxhletation method with 1 l ethanol 96 % solvent. The phytochemical screenings test uses standard reagent by observing color changes, sediment, and foam. The result of the study that the extract of black ear mushroom (Auricularia nigricans) showed a red color after being given Dragendorrf reagent, terpenoid reagent test, flavonoid reagent test, gave a green color change after being given phenolic and tannin reagent test, did not give a red color in the steroid reagent test and did not produce foam in the saponin test. The conclusion of the study that the extract of black ear mushroom (Auricularia nigricans) contained secondary metabolite compounds tannins, terpenoids, flavonoids, phenolics, and alkaloids.
ANALISIS BEBAN KERJA PERSONIL SORTIR PADA PROSES PRODUKSI SEDIAAN KAPSUL LUNAK DI PT X Suryandari, Mercyska; Hatidja, Siti Annurijati; Avanti, Christina
Journal of Research and Technology Vol. 6 No. 1 (2020): JRT Volume 6 No 1 Jun 2020
Publisher : 2477 - 6165

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (376.398 KB) | DOI: 10.55732/jrt.v6i1.151

Abstract

Productivity is one of the important aspects that must be owned by a company to achieve the goals. Therefore, to improve productivity, it is necessary to analyze the workload of employees and improve the work procedures. Workload analysis carried out in this study aimed to determine the optimal workforce requirements of the sorting process in the soft capsule production unit at Pharmaceutical Company PT X. The observational method has been applied to this study. The data of this study were obtained by observing the process directly and conducting face-to-face interviews with the employees at the location of soft capsule production. Based on the workload analysis using a Full-Time Equivalent (FTE) method, it was found that a total value of 2.07 was obtained from the eleven activities in the sorting section. If the FTE was assessed for each person in the sorting section, then the FTE value for each personnel was 0.52. This value is in the underload category. Therefore, the number of personnel and the work procedures need to be adjusted.
UJI AKTIVITAS ANTIOKSIDAN TEH SEDUHAN DAUN ROSEMARY (Rosmarinus officinalis L.) DAN DAUN STEVIA (Stevia rebaudiana) DENGAN PERBANDINGAN (60:40) Mercyska, Mercyska Suryandari; Nur Indahwati, Sephia; Gondo Kusumo, , Galuh
Jurnal Komunitas Farmasi Nasional Vol. 3 No. 02 (2023): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Rosemary is an herbal plant whose content has compounds. Antioxidant that can prevent the occurrence of damage due to free addiction. This study wanted to find out the content of antioxidant that are obtained in steeping rosemary tea with using additional weetener stevia leaves. Antioxidant testing of leaf steeping tea. Rosemary and stevia leaves using the DPPH method observations were conducted at a wavelength of 522 nm, using a Vitamin C comparator. Replication was performed 3 times the treatment with a difference in brewing time of 5 minutes, 10 minutes and 15 minutes. From the results of the stury and observations obtained % Vitamin C concentration 1 ppm 15.45%, concentration 2 ppm 13.18%, concentration 3 ppm 26.52%, concentration 4 ppm 28.79%, concentration 5 ppm 38.33%. As for the result of % steeping rosemary leaf tea and stevia leaves on sample A brewed for 5 minutes on average % soaking 46.83%, sample B brewing for 10 minutes on average 32.01% dampening, and 15 minutes samle C brewing average % dampering 38.8%. The results of the antioxidant activity test of tea steeping rosemary leaves and stevia leaves in a ratio of (60:40) are that there is a strong antioxidant activity.
IDENTIFICATION AND QUANTIFICATION OF MAJOR POLYPHENOLS IN DIFFERENT TYPES OF OLIVE OIL: A SYSTEMATIC REVIEW OF HEALTH BENEFITS Suryandari, Mercyska; Isdianto, Andik; Fitrianti, Novariza
International Journal of Islamic and Complementary Medicine Vol. 5 No. 1 (2024): International Journal of Islamic and Complementary Medicine
Publisher : International Islamic Medicine Forum

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55116/IJICM.V5I1.86

Abstract

Olive oil is a key component of the Mediterranean diet, renowned for its flavor and health benefits, especially for its polyphenol content. These polyphenols have strong antioxidant properties, protecting cells from oxidative stress and reducing the risk of chronic diseases such as cardiovascular disease, cancer, and neurodegenerative disorders. This study aims to systematically identify and quantify the main polyphenols in different types of olive oil, including Extra Virgin Olive Oil (EVOO), Virgin Olive Oil (VOO), Refined Olive Oil (ROO), Pure Olive Oil (POO), and Pomace Olive Oil. Using a qualitative approach and descriptive analysis, a comprehensive literature study was conducted to collect and evaluate research on polyphenol content in various olive oils. The results showed significant differences in polyphenol profiles. EVOO, which is produced through cold pressing without heat or chemicals, has the highest polyphenol content, offers superior health benefits and complex flavors. VOO, although more processed, still contained moderately high polyphenols, suitable for medium temperature cooking. ROO, which is extensively processed, has lower polyphenol levels, ideal for high temperature cooking but with fewer health benefits. POO, a blend of VOO and ROO, offers a balance of flavor and practicality. Pomace Olive Oil, with the lowest polyphenol content, is used mainly for industrial frying due to its high smoke point. In conclusion, this study emphasizes the importance of choosing the type of olive oil based on its use and health benefits. EVOO is optimal for raw or lightly cooked dishes, VOO for all- purpose cooking, and ROO and Pomace Olive Oil for high temperature applications. This research guides consumers and manufacturers in making the right choice to optimize the health benefits of olive oil.
PRESCRIPTION PROFILE OF ANTIHYPERTENSIVE DRUGS IN PREECLAMPSIA PATIENTS AT KIRANA HOSPITAL Lubada, Eziah Ika; Fandinata, Selly Septi; Alfiana, Silvina Sita; Suryandari, Mercyska; Isdianto, Andik
International Journal of Islamic and Complementary Medicine Vol. 5 No. 1 (2024): International Journal of Islamic and Complementary Medicine
Publisher : International Islamic Medicine Forum

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55116/IJICM.V5I1.87

Abstract

Preeclampsia is a complication of pregnancy with symptoms of hypertension ≥ 140/90 mmHg and proteinuria ≥ 0.3 grams/24 hours or 30 mg/dl (+1 dipstick) arising after more than 20 weeks of gestation in previously normotensive pregnant women. Maternal deaths in Indonesia in 2021 related to hypertension in pregnancy reached 1077 cases (Source: Directorate General of Public Health, Ministry of Health, 2021). Pharmacological therapy intervention, antihypertensive treatment is also needed in addition to maintaining a healthy lifestyle. The purpose of the study was to determine the description of pharmacological therapy including the pharmacological class of drugs, drug names, drug doses, rules of use, and types of antihypertensive drug therapy (single / combination) in patients with preeclampsia. This type of descriptive observational research is retrospective with total sampling obtained from medical records and patient prescriptions. The results of this study were the incidence of preeclampsia aged 35 years and over by 21 patients (36%) and the most common diagnosis was mild preeclampsia by 38 samples (66%). The use of nifedipine which is included in the CCB (Calcium Channel Blocker) group was 42 respondents (72%). Meanwhile, the use of methyldopa which is included in the central sympatholytic group was 17 respondents (28%). In the single therapy type study, 59 prescriptions (100%) used nifedipine or methyldopa. Pregnant women are encouraged to routinely conduct antenatal care checks at the hospital every month.
EFFECT OF EXTRACTION METHOD ON DETERMINING TOTAL PHENOL CONTENT OF ROSEMARY EXTRACT Mercyska Suryandari, Mercyska; Dwi Aristyawan, Andhika; Wefa, Ali; Ngurah Rio Juliana, I Made
SITAWA : Jurnal Farmasi Sains dan Obat Tradisional Vol. 4 No. 1 (2025): SITAWA : Jurnal Farmasi Sains dan Obat Tradisional
Publisher : LPPM Akademi Farmasi Imam Bonjol Bukittinggi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62018/sitawa.v4i1.120

Abstract

Rosemary is a unique herb that is commercially available for use as an antioxidant. On the other hand, it can also be used as a food preservative, as it prevents oxidation and microbial contamination. Therefore, rosemary can be useful for replacing or even reducing synthetic antioxidants in food. Antioxidants are compounds that can inhibit oxidation reactions, by binding free radicals and molecules very effectively. As a result, cell damage will be inhibited. Known sources of antioxidants can be synthetic antioxidants and natural antioxidants originating from compounds contained in plants, one of which is phenolic compounds. To obtain phenolic compounds, extraction is carried out using maceration and digestion methods. The solvent choice here uses 80% ethanol solvent. The results obtained in this study were that 80% ethanol extract of rosemary was extracted using the maceration method, with a total phenol content of 11.84 mg GAE/g extract, while using digestion the total phenol content was 9.61 mg GAE/g extract. It can be concluded that the extraction method can influence the results of total phenol content with a significant difference with a p value <0.05
KEAMANAN DAN EFEKTIVITAS MINYAK ZAITUN SEBAGAI TERAPI TOPIKAL DALAM MENGATASI PERADANGAN KULIT Suryandari, Mercyska; Isdianto, Andik
JURNAL EDUCATION AND DEVELOPMENT Vol 13 No 1 (2025): Vol 13 No 2 Mei 2025
Publisher : Institut Pendidikan Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37081/ed.v13i1.6890

Abstract

Penelitian ini mengkaji efek terapi minyak zaitun terhadap peradangan kulit melalui tinjauan literatur. Minyak zaitun, yang telah lama digunakan dalam pengobatan tradisional, mengandung komponen bioaktif seperti asam oleat, polifenol (hidroksitirosol dan oleuropein), serta vitamin E, yang memiliki sifat anti-inflamasi, antioksidan, dan antimikroba. Metode penelitian yang digunakan adalah literature review, yang mengumpulkan dan menganalisis berbagai sumber relevan, termasuk artikel jurnal, buku, laporan penelitian, dan sumber online terpercaya. Hasil penelitian menunjukkan bahwa asam oleat dalam minyak zaitun dapat mengurangi produksi molekul pro-inflamasi, polifenol mampu menetralkan radikal bebas dan mengurangi stres oksidatif, sementara vitamin E melindungi sel-sel kulit dari kerusakan oksidatif dan mempercepat regenerasi jaringan kulit. Beberapa penelitian klinis dan pra-klinis mendukung efek anti-inflamasi minyak zaitun, menunjukkan pengurangan gejala peradangan seperti kemerahan, gatal, dan pembengkakan pada pasien dengan dermatitis atopik. Penelitian ini memberikan dasar yang kuat untuk penelitian lebih lanjut dan aplikasi klinis minyak zaitun sebagai terapi topikal yang aman dan efektif dalam mengatasi peradangan kulit. Dengan demikian, minyak zaitun adalah alternatif bahan alami yang menjanjikan untuk perawatan peradangan kulit