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Edukasi Manfaat Tanaman Piperaceae dan Pelatihan Pembuatan Hand Sanitizer Alami kepada Siswa SMK Farmasi Surabaya Meyke Herina Syafitri; Mercyska Suryandari; M.A. Hanny Ferry Fernanda
Nusantara: Jurnal Pengabdian kepada Masyarakat Vol. 3 No. 2 (2023): Mei : Jurnal Pengabdian Kepada Masyarakat
Publisher : Lembaga Pengembangan Kinerja Dosen

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55606/nusantara.v3i2.1226

Betel leaves contain phenols that function as powerful antiseptics. Hand sanitizer (HS) is a product that can kill parasites on the hands and is easy to use. Therefore, in this event, education will be provided to the students of SMK Farmasi Surabaya regarding the benefits of betel leaves, followed by a training session on making hand sanitizers containing extract. The participant's level of understanding is evaluated by comparing the scores obtained before and after receiving information from the speaker. A questionnaire is given to allow participants to evaluate the overall conduct of the event, and they are invited to try the hand sanitizers prepared by the team. The results show that 76% of the participants achieved higher scores, 24% maintained the same scores, and none of the participants received lower scores compared to the pre-test. Overall, the participants expressed that the event was very beneficial.

Fraksinasi dan Identifikasi Ektrak Daun Mitragyna Speciosa Menggunakan Metode Kromatografi Fernanda, M.A. Hanny Ferry; Suryandari, Mercyska; Sudarwati, Tri Puji Lestari
FARMASIS: Jurnal Sains Farmasi Vol 2 No 2 (2021): Farmasis : Jurnal Sains Farmasi
Publisher : Universitas PGRI Adi Buana, Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36456/farmasis.v2i2.4072

Background: Mitragyna Speciosa or better known as Kratom is a typical plant from the Putusibau area, West Kalimantan. The most widely used part of this plant is the leaves. The kratom plant contains alkaloids, flavonoids, phenols, terpenoids-steroids, triterpenoids, saponins, and tannins. Alkaloid content is the most dominant and has benefits in this plant so it is necessary to do fractionation and identification of secondary metabolites. Objective: To fractionate and identify secondary metabolites from Mitragyna Speciosa leaf extract. Methods: The fractionation method was carried out using Column Chromatography while for identification using Thin Layer Chromatography. Results: 80 fractions were obtained from the column chromatography results, while the results of identification using thin layer chromatography showed that only the 2nd and 3rd fractions were obtained. The second fraction has two spots with Rf values of 0.51 and 0.73 and in the third fraction there are three spots with Rf values of 0.21; 0.52, and 0.74. Conclusion: Fractionation and identification by chromatographic method can be used as initial screening for secondary metabolite content in Mitragyna Speciosa leaf extract.

ANALISIS BEBAN KERJA PERSONIL SORTIR PADA PROSES PRODUKSI SEDIAAN KAPSUL LUNAK DI PT X Suryandari, Mercyska; Hatidja, Siti Annurijati; Avanti, Christina
Journal of Research and Technology Vol. 6 No. 1 (2020): JRT Volume 6 No 1 Jun 2020
Publisher : 2477 - 6165

Productivity is one of the important aspects that must be owned by a company to achieve the goals. Therefore, to improve productivity, it is necessary to analyze the workload of employees and improve the work procedures. Workload analysis carried out in this study aimed to determine the optimal workforce requirements of the sorting process in the soft capsule production unit at Pharmaceutical Company PT X. The observational method has been applied to this study. The data of this study were obtained by observing the process directly and conducting face-to-face interviews with the employees at the location of soft capsule production. Based on the workload analysis using a Full-Time Equivalent (FTE) method, it was found that a total value of 2.07 was obtained from the eleven activities in the sorting section. If the FTE was assessed for each person in the sorting section, then the FTE value for each personnel was 0.52. This value is in the underload category. Therefore, the number of personnel and the work procedures need to be adjusted.

UJI AKTIVITAS ANTIOKSIDAN TEH SEDUHAN DAUN ROSEMARY (Rosmarinus officinalis L.) DAN DAUN STEVIA (Stevia rebaudiana) DENGAN PERBANDINGAN (60:40) Mercyska, Mercyska Suryandari; Nur Indahwati, Sephia; Gondo Kusumo, , Galuh
Jurnal Komunitas Farmasi Nasional Vol. 3 No. 02 (2023): Jurnal Komunitas Farmasi Nasional
Publisher : Akademi Farmasi Yarsi Pontianak

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Rosemary is an herbal plant whose content has compounds. Antioxidant that can prevent the occurrence of damage due to free addiction. This study wanted to find out the content of antioxidant that are obtained in steeping rosemary tea with using additional weetener stevia leaves. Antioxidant testing of leaf steeping tea. Rosemary and stevia leaves using the DPPH method observations were conducted at a wavelength of 522 nm, using a Vitamin C comparator. Replication was performed 3 times the treatment with a difference in brewing time of 5 minutes, 10 minutes and 15 minutes. From the results of the stury and observations obtained % Vitamin C concentration 1 ppm 15.45%, concentration 2 ppm 13.18%, concentration 3 ppm 26.52%, concentration 4 ppm 28.79%, concentration 5 ppm 38.33%. As for the result of % steeping rosemary leaf tea and stevia leaves on sample A brewed for 5 minutes on average % soaking 46.83%, sample B brewing for 10 minutes on average 32.01% dampening, and 15 minutes samle C brewing average % dampering 38.8%. The results of the antioxidant activity test of tea steeping rosemary leaves and stevia leaves in a ratio of (60:40) are that there is a strong antioxidant activity.

IDENTIFICATION AND QUANTIFICATION OF MAJOR POLYPHENOLS IN DIFFERENT TYPES OF OLIVE OIL: A SYSTEMATIC REVIEW OF HEALTH BENEFITS Suryandari, Mercyska; Isdianto, Andik; Fitrianti, Novariza
International Journal of Islamic and Complementary Medicine Vol. 5 No. 1 (2024): International Journal of Islamic and Complementary Medicine
Publisher : International Islamic Medicine Forum

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55116/IJICM.V5I1.86

Olive oil is a key component of the Mediterranean diet, renowned for its flavor and health benefits, especially for its polyphenol content. These polyphenols have strong antioxidant properties, protecting cells from oxidative stress and reducing the risk of chronic diseases such as cardiovascular disease, cancer, and neurodegenerative disorders. This study aims to systematically identify and quantify the main polyphenols in different types of olive oil, including Extra Virgin Olive Oil (EVOO), Virgin Olive Oil (VOO), Refined Olive Oil (ROO), Pure Olive Oil (POO), and Pomace Olive Oil. Using a qualitative approach and descriptive analysis, a comprehensive literature study was conducted to collect and evaluate research on polyphenol content in various olive oils. The results showed significant differences in polyphenol profiles. EVOO, which is produced through cold pressing without heat or chemicals, has the highest polyphenol content, offers superior health benefits and complex flavors. VOO, although more processed, still contained moderately high polyphenols, suitable for medium temperature cooking. ROO, which is extensively processed, has lower polyphenol levels, ideal for high temperature cooking but with fewer health benefits. POO, a blend of VOO and ROO, offers a balance of flavor and practicality. Pomace Olive Oil, with the lowest polyphenol content, is used mainly for industrial frying due to its high smoke point. In conclusion, this study emphasizes the importance of choosing the type of olive oil based on its use and health benefits. EVOO is optimal for raw or lightly cooked dishes, VOO for all- purpose cooking, and ROO and Pomace Olive Oil for high temperature applications. This research guides consumers and manufacturers in making the right choice to optimize the health benefits of olive oil.

PRESCRIPTION PROFILE OF ANTIHYPERTENSIVE DRUGS IN PREECLAMPSIA PATIENTS AT KIRANA HOSPITAL Lubada, Eziah Ika; Fandinata, Selly Septi; Alfiana, Silvina Sita; Suryandari, Mercyska; Isdianto, Andik
International Journal of Islamic and Complementary Medicine Vol. 5 No. 1 (2024): International Journal of Islamic and Complementary Medicine
Publisher : International Islamic Medicine Forum

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55116/IJICM.V5I1.87

Preeclampsia is a complication of pregnancy with symptoms of hypertension ≥ 140/90 mmHg and proteinuria ≥ 0.3 grams/24 hours or 30 mg/dl (+1 dipstick) arising after more than 20 weeks of gestation in previously normotensive pregnant women. Maternal deaths in Indonesia in 2021 related to hypertension in pregnancy reached 1077 cases (Source: Directorate General of Public Health, Ministry of Health, 2021). Pharmacological therapy intervention, antihypertensive treatment is also needed in addition to maintaining a healthy lifestyle. The purpose of the study was to determine the description of pharmacological therapy including the pharmacological class of drugs, drug names, drug doses, rules of use, and types of antihypertensive drug therapy (single / combination) in patients with preeclampsia. This type of descriptive observational research is retrospective with total sampling obtained from medical records and patient prescriptions. The results of this study were the incidence of preeclampsia aged 35 years and over by 21 patients (36%) and the most common diagnosis was mild preeclampsia by 38 samples (66%). The use of nifedipine which is included in the CCB (Calcium Channel Blocker) group was 42 respondents (72%). Meanwhile, the use of methyldopa which is included in the central sympatholytic group was 17 respondents (28%). In the single therapy type study, 59 prescriptions (100%) used nifedipine or methyldopa. Pregnant women are encouraged to routinely conduct antenatal care checks at the hospital every month.

KEAMANAN DAN EFEKTIVITAS MINYAK ZAITUN SEBAGAI TERAPI TOPIKAL DALAM MENGATASI PERADANGAN KULIT Suryandari, Mercyska; Isdianto, Andik
JURNAL EDUCATION AND DEVELOPMENT Vol 13 No 1 (2025): Vol 13 No 2 Mei 2025
Publisher : Institut Pendidikan Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37081/ed.v13i1.6890

Penelitian ini mengkaji efek terapi minyak zaitun terhadap peradangan kulit melalui tinjauan literatur. Minyak zaitun, yang telah lama digunakan dalam pengobatan tradisional, mengandung komponen bioaktif seperti asam oleat, polifenol (hidroksitirosol dan oleuropein), serta vitamin E, yang memiliki sifat anti-inflamasi, antioksidan, dan antimikroba. Metode penelitian yang digunakan adalah literature review, yang mengumpulkan dan menganalisis berbagai sumber relevan, termasuk artikel jurnal, buku, laporan penelitian, dan sumber online terpercaya. Hasil penelitian menunjukkan bahwa asam oleat dalam minyak zaitun dapat mengurangi produksi molekul pro-inflamasi, polifenol mampu menetralkan radikal bebas dan mengurangi stres oksidatif, sementara vitamin E melindungi sel-sel kulit dari kerusakan oksidatif dan mempercepat regenerasi jaringan kulit. Beberapa penelitian klinis dan pra-klinis mendukung efek anti-inflamasi minyak zaitun, menunjukkan pengurangan gejala peradangan seperti kemerahan, gatal, dan pembengkakan pada pasien dengan dermatitis atopik. Penelitian ini memberikan dasar yang kuat untuk penelitian lebih lanjut dan aplikasi klinis minyak zaitun sebagai terapi topikal yang aman dan efektif dalam mengatasi peradangan kulit. Dengan demikian, minyak zaitun adalah alternatif bahan alami yang menjanjikan untuk perawatan peradangan kulit

MANFAAT MINYAK ZAITUN SEBAGAI AGEN TERAPI ALAMI UNTUK PENYEMBUHAN LUKA Isdianto, Andik; Suryandari, Mercyska; Fitrianti, Novariza
JURNAL EDUCATION AND DEVELOPMENT Vol 13 No 1 (2025): Vol 13 No 2 Mei 2025
Publisher : Institut Pendidikan Tapanuli Selatan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37081/ed.v13i1.6408

Penelitian ini mengkaji efek terapi minyak zaitun terhadap penyembuhan luka melalui tinjauan literatur. Minyak zaitun, yang telah lama digunakan dalam pengobatan tradisional, mengandung komponen bioaktif seperti asam oleat, vitamin E, dan polifenol yang memiliki sifat anti-inflamasi, antimikroba, dan antioksidan. Metode yang digunakan dalam penelitian ini adalah literature review, di mana artikel jurnal, buku, dan laporan penelitian yang relevan dianalisis untuk mengidentifikasi tema utama dan pola dalam literatur yang ada. Hasil tinjauan menunjukkan bahwa aplikasi topikal minyak zaitun dapat mengurangi peradangan, mencegah infeksi, meningkatkan produksi kolagen, dan menjaga hidrasi kulit, sehingga mempercepat proses penyembuhan luka. Studi klinis dan preklinis mendukung temuan ini, menunjukkan bahwa minyak zaitun dapat meningkatkan penutupan luka, mengurangi rasa sakit, dan meningkatkan kualitas hidup pasien. Selain itu, penelitian juga menemukan bahwa minyak zaitun memiliki efek ganda pada luka akut, termasuk pengaruh positif terhadap produksi sitokin dan migrasi fibroblas dermal melalui aktivasi jalur Nrf2. Meskipun hasil-hasil ini menjanjikan, masih diperlukan penelitian lebih lanjut untuk mengkonfirmasi temuan-temuan ini dan memperluas pemahaman tentang aplikasi klinis minyak zaitun dalam berbagai jenis luka dan kondisi kulit. Secara keseluruhan, minyak zaitun muncul sebagai terapi topikal yang efektif dan alami untuk penyembuhan luka, yang dapat dipertimbangkan sebagai alternatif atau pelengkap dalam perawatan luka dengan dukungan bukti ilmiah yang semakin kuat dari penelitian yang berkelanjutan.

EDUKASI PENGENALAN GEJALA DIABETES MELLITUS PADA ANAK UNTUK MENINGKATKAN KEWASPADAAN TENTANG BAHAYA DIABETES PADA ANAK Eziah Ika Lubada; Meyke Herina Syafitri; Mercyska Suryandari; Rizky Darmawan
Jurnal Gembira: Pengabdian Kepada Masyarakat Vol 1 No 05 (2023): OKTOBER 2023
Publisher : Media Inovasi Pendidikan dan Publikasi

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Diabetes Mellitus (DM) tidak hanya terjadi pada orang Dewasa tetapi dapat pula terjadi pada Anak. Insiden Diabetes Mellitus (DM) Tipe-1 pada anak di dunia dan Indonesia terus meningkat. Berdasarkan data Ikatan Dokter Anak Indonesia (IDAI), tercatat 1220 dengan DM tipe-1 pada tahun 2018. Kesadaran masyarakat dan tenaga kesehatan mengenai diabetes pada anak masih rendah, yang direfleksikan melalui tingginya angka anak yang terdiagnosis dengan DM tipe-1 saat mengalami ketoasidosis diabetikum mencapai 71% pada tahun 2017 (Pulungan et al., 2019). Oleh karena itu, Dalam meningkatkan pemahaman ibu mengenai pentingnya waspada bahaya diabetes melitus pada anak, maka dilaksanakan Kegiatan Pengabdian pada Masyarakat dengan judul “Penyuluhan Edukasi Diabetes Mellitus Pada Anak Untuk Meningkatkan Kewaspadaan Tentang Bahaya Diabetes Pada Anak”, pada ibu-ibu warga RT 03 RW 07 Jalan Dukuh Kupang Gang Lebar Surabaya pada tanggal 27 Mei 2023. Sebelum penyuluhan dimulai, peserta diberi pre-test, lalu setelah penyuluhan selesai dilaksanakan peserta diberi post-test, hal ini dilakukan untuk menguji pemahaman peserta mengenai materi sebelum dan sesudah penyuluhan. Hasil dari pre-test dan post-test tersebut diuji statistic menggunakan uji t-berpasangan, hasilnya p-value = 0.03 < 0.05 dan rata-rata post-tets lebih tinggi dari pre-tets, sehingga ada peningkatan signifikan pemahaman peserta setelah penyuluhan tentang bahaya diabetes pada anak.

ANALISIS BEBAN KERJA PERSONIL SORTIR PADA PROSES PRODUKSI SEDIAAN KAPSUL LUNAK DI PT X Suryandari, Mercyska; Hatidja, Siti Annurijati; Avanti, Christina
Journal of Research and Technology Vol. 6 No. 1 (2020): JRT Volume 6 No 1 Jun 2020
Publisher : 2477 - 6165

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55732/jrt.v6i1.151

Productivity is one of the important aspects that must be owned by a company to achieve the goals. Therefore, to improve productivity, it is necessary to analyze the workload of employees and improve the work procedures. Workload analysis carried out in this study aimed to determine the optimal workforce requirements of the sorting process in the soft capsule production unit at Pharmaceutical Company PT X. The observational method has been applied to this study. The data of this study were obtained by observing the process directly and conducting face-to-face interviews with the employees at the location of soft capsule production. Based on the workload analysis using a Full-Time Equivalent (FTE) method, it was found that a total value of 2.07 was obtained from the eleven activities in the sorting section. If the FTE was assessed for each person in the sorting section, then the FTE value for each personnel was 0.52. This value is in the underload category. Therefore, the number of personnel and the work procedures need to be adjusted.

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