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Hari Santoso
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KAJIAN EKSTRAK METANOLIK Scurrula atropurpurea B1. DANS TERHADAP KADAR TRIGLISERIDA PADA TIKUS WISTAR BETINA Munawaroh, Nur Shofiyah; Athiroh, Nour; Santoso, Hari
BIOSAINTROPIS (BIOSCIENCE-TROPIC) Vol 2, No 1 (2016): Sumberdaya Lingkungan
Publisher : FMIPA - UNIVERSITY ISLAM OF MALANG

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Abstract

High trigliserida can health endangered causes some high lipoprotein into trigliserida contain colesterol. The leaf and stem tea parasite Scurrula atropurpurea (Bl.) Dans contains is alkaloid, flavonoid, glikosida, triterpen, saponin, dan tanin shared as antioksidan. To observe safety and obtain information of effect toxic after explanation experiment in a recur for curtain time, so a sediaan perlu dilakukan toxic tests with used 2-3 test animal from difference galur, wherther in a akut (24 hour), sub-chronic (28 day) and sub-chronic (90 day). Subkronik test doing of male rats for 28 day, and result showed that, the Methanolic Extract of Scurrula atropurpurea(Bl.) Dans (MESA) not causes for serum trouble biochemical clinic of rats liver.  Research aims is assess further the gift Methanolic Extract of Scurrula atropurpurea (Bl.) Dans of trigliserida for female rats (Rattus norvegicus ) strain Wistarfor 28 days (study sub-chronic). This research used the female rats Rattus norvegicus Strain Wistar and have done for 28 day, with the laboratoric experiment metode witha model test only post control grup desain. There are 4 treatment grup is control, P1(dosage 250 mg/KgBW), P2 (dosage  500  mg/KgBW),  P3  (dosage  1000  mg/KgBW). Rats were fasted for 14-18 hours before it given treatment. EMSA awarded at least 5 times a week during 28 day. The analysis used is One Way ANOVA to figure out the difference of the increase of Trigliserida.Result showed that the Methanolic Extractof Scurrula atropurperea (Bl.) Dansor treatment group did not differ to control, this mean that, have not effect of trigliserida for female rats with dosage 250 mg/KgBW, 500 mg/KgBW dan 1000 mg/KgBW. Kadar trigliserida yang tinggi dapat membahayakan kesehatan karena beberapa lipoprotein yang tinggi kandungan trigliseridanya juga mengandung kolesterol. Daun dan batang benalu teh Scurrula atropurpurea (Bl.) Dans tanaman ini mengandung alkaloid, flavonoid, glikosida, triterpen, saponin, dan tanin yang berperan sebagai antioksidan. Untuk melihat keamanan dan memperoleh informasi adanya efek toksik setelah pemaparan sediaan uji secara berulang dalam jangka waktu tertentu, maka suatu sediaan perlu dilakukan uji toksisitas dengan menggunakan 2-3 hewan uji coba dari galur yang berbeda, baik secara akut(24 jam), subkronik(28 hari) dan subkronik (90 hari). Penelitian bertujuan untuk mengkaji lebih lanjut pengaruh pemberian ekstrak metanolik Scurrula atropurpurea (EMSA) terhadap kadar trigliserida pada tikus betina selama 28 hari (studi subkronik).Penelitian ini menggunkan tikus betina dan telah dilakukan selama 28 hari, dengan metode eksperimental laboratorik dengan model post test only control grup design. Terdapat 4 kelompok perlakuan yaitu Kontrol, P1(dosis 250 mg/KgBB), P2(dosis 500 mg/KgBB), P3 (dosis 1000 mg/KgBB),sebelum diberi perlakuan tikus dipuasakan selama 14-18 jam. EMSA diberikan minimal 5 kali dalam seminggu selama 28 hari. Analisa yang digunakan yaitu uji one way ANOVA untuk mengetahui perbedaan pada setiap kadarTrigliserida.Hasil penelitian menunjukkan bahwa Ekstrak Metanolik Scurrula atropurperea(Bl.) Dans terhadap tikus perlakuan tidak beda nyata dibandingkan kontrol, hal ini dapat diartikan bahwa EMSA tidakmempengaruhi kadartrigliserida padatikus betina dengan dosis 250 mg/KgBB, 500 mg/KgBB dan 1000 mg/KgBB.
Keragaman Koloni Bakteri Indigenous Pengolahan Limbah Cair Industri Penyamakan Kulit Wardani, Aisyah; syauqi, ahmad; Santoso, Hari
BIOSAINTROPIS (BIOSCIENCE-TROPIC) Vol 1, No 1 (2015): Kearifan Lokal dan Biologi pada Usaha Perbaikan Kualitas Habitat
Publisher : FMIPA - UNIVERSITY ISLAM OF MALANG

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Abstract

Tanning industry waste is potential to pollute the environment because it is using a  harmful chemical materials. One of many effort to prohibit the environmental pollution is a bioremediation using bacteria because bacteria can grow and adapt to any subtrats that has a organic materials. The diversity of bacteria is important to know because the bacteria covers most large species diversity on earth and its role as bioremediation. The purpose of  this research is to determine the value of the diversity index and the types of indigenous gram bacteria in waste water Leather Tanning Industry Malang. Data has been analyzed results of measurements of pH, temperature, conductivity, the number of  bacteria colonies, bacterial community structure (diversity, evenness, richness and dominance) and the results of bacterial gram staining.Diversity of indigenous bacteria colonies that has been found are low and the value is 0,36; 1,30 and 0,015. Type of indigenous gram bacteria found are streptococci negative (11%), streptococci positive (34%), Streptobacilli negative (11%), streptobacilli positive (34%), coccus negative (5%) and coccus positive (5%). Keywords:Diversity, Gram Strain, Bacteria, Waste Water, Tanning Industry
Peran Air Perasan Pegagan (Centella asiatica) terhadap SOD pada Tikus alaiya, Sholikha; Athiroh AS, Nour; santoso, hari
BIOSAINTROPIS (BIOSCIENCE-TROPIC) Vol 1, No 1 (2015): Kearifan Lokal dan Biologi pada Usaha Perbaikan Kualitas Habitat
Publisher : FMIPA - UNIVERSITY ISLAM OF MALANG

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Abstract

Pegagan (Centella asiatica (Linn.) Urban) 1 adalah tumbuhan berpotensi dalam peningkatan fungsi kognitif dengan kandungan senyawa triterpenoid. Senyawa triterpenoid merupakan antioksidan alami berasal dari tumbuhan pegagan. Adanya aktivitas sel tidak seimbang akan menurunkan fungsi kognitif, menimbulkan insiden dugaan awal penyakit demensia di Indonesia yang terjadi pada kelompok lanjut usia (lansia). Tujuan penelitian adalah untuk mengetahui pengaruh pemberian air perasan pegagan1 dapat meningkatkan kadar  Superoxide dismutase (SOD) pada tikus tua dan untuk mengetahui konsentrasi optimum air perasan pegagan1 dapat meningkatkan kadar Superoxide dismutase (SOD) pada tikus tua. Metode penelitian eksperimental laboratorik model post test only control group design. Analisis data: uji One Way ANOVA dan Post Hoc. Penelitian ± 5 bulan menggunakan tikus (Rattus norvegicus) galur wistar jantan, terbagi 5 kelompok perlakuan masing-masing 5 ulangan yaitu Kontrol (-) tikus usia normal; Kontrol (+) tikus usia tua; K III (tikus tua+2% APP); KIV (tikus tua+4% APP); KV (tikus tua+8% APP). Hasil penelitian menunjukkan air perasan pegagan1 (APP) mampu meningkatkan kadar SOD pada tikus tua dalam konsentrasi 2%. Nilai optimum APP adalah 4%. Sehingga, peran pemberian APP sangat berpengaruh baik dalam melindungi stabilitas antioksidan dari senyawa radikal bebas pada tikus tua.Kata kunci: Kadar Superoxide dismutase, Pegagan (Centella asiatica), Tikus Tua
PAPARAN 28 HARI EKSTRAK METANOLIK Scurrula atropurpurea TERHADAP KADAR SGPT TIKUS BETINA Mahyan, Argus; Athiroh, Nour; Santoso, Hari
BIOSAINTROPIS (BIOSCIENCE-TROPIC) Vol 2, No 1 (2016): Sumberdaya Lingkungan
Publisher : FMIPA - UNIVERSITY ISLAM OF MALANG

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Abstract

Tea parasite Scurrulaatropurpurea (Bl.) Dans contains several secondary metabolites, one of which is Flavonoids from Quersetin that may act as antioxidants; the presence of antioxidants can neutralize and protect the liver from free radicals. Liver cell damage can be seen from the results of clinical biochemical test form levels of Serum Glutamic Pyrufic Transaminase (SGPT). The purpose of this study was to determine the effect of methanolic extract Scurrulaatropurpurea (MESA) to the SGPT levels of  female white mice for 28 days. Data were analysed using ANOVA in SPSS version 17.0. The numbers of tested animals were 20 female white mice which was divided rat into four groups, each group contained 5 mice. Group 1 is a dick, group 2, 3 and 4 as a treatment.  A significant difference between the mean treatment groups compared with the control group. No significant value difference between the groups was p> 0.05. Therefore, EMSA that was given to female mice for 28 days with a dose of 250 mg / KgBW, 500 mg / KgBW and 1000 mg / KgBW in the treatment group all the doses were not significantly different compared with the controls, in this case the level of SGPT female white mice was normal.Benalu teh (Scurrula atropurpurea (Bl.) Dans mengandung beberapa senyawa metabolit sekunder  salah satunya yaitu Flavonoid dari Quersetin yang berperan sebagai antioksidan. Keberadaan antioksidan mampu menetralkan dan melindungi hati dari radikal bebas. Kerusakan sel hati dapat dilihat dari hasil pemeriksaan biokimia klinis berupa kadar Serum Glutamic Pyrufic Transaminase (SGPT). Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pemberian Ekstrak Metanolik Scurrula atropurpurea (EMSA) terhadap kadar SGPT pada tikus putih betina selama 28 hari. Jenis penelitian ini adalah penelitian eksperimental dan analisis data menggunakan uji ANOVA dengan SPSS versi 17.0. Jumlah hewan uji adalah 20 ekor tikus putih betina dibagi menjadi 4 kelompok, masing-masing kelompok terdapat 5 ekor tikus. Perbedaan signifikan antara rata-rata kelompok perlakuan dibandingkan dengan kelompok kontrol. Berdasarkan hasil penelitian menunjukkan bahwa tidak terdapat perbedaan  yang signifikan antara semua kelompok dengan nilai  p>0.05. Maka dari itu EMSA yang diberikan kepada tikus betina selama 28 hari dengan dosis 250 mg/KgBB, 500 mg/KgBB dan 1000 mg/KgBB pada kelompok perlakuan semua dosis tidak berbeda nyata dibandingkan dengan kontrol, dalam hal ini kadar SGPT pada tikus putih betina bersifat normal. 
The Degree of Cystocele and Rectocele with Hiatal Area Levator Ani Moegni, Fernandi; Santoso, Hari
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (206.803 KB) | DOI: 10.32771/inajog.v5i4.566

Abstract

Objective: To investigate the degree of cystocele and rectocele with a maximum of levator hiatal area (AHL) during Valsava. Methods: Secondary data analysis of 90 patients with uterine prolapse January 2012 to November 2013 in the clinic Uroginekologi RSCM, Jakarta. 3D/4D ultrasound measurement and pelvic organ prolapse system Quantification (POP-Q) stage I-IV cystocele and rectocelestage I-IV. All statistical analyses were analyzed using Stata 20 for Windows. Results: Significant difference cystocele stage I-II (n = 25) with stage III-IV (n = 65), the maximum AHL with a difference of 4.33 cm2 (p = 0.040). In rectocele stage I-II (n = 64) and stage III-IV (n = 26) of 3.85 cm2 (p = 0.130). AUC values for stage I-II and III-IV cystocele was 0.607 (IK95% from 0.467 to 0.738), and the ROC for rectocele was 0.603 (IK95% from 0.472 to 0.734). The ROC optimal cut point for cystocele stage I-II with III-IV with the highestsensitivity and specificity is 29 cm2 (0.523 sensitivity, specificity 0.520), the rectocele is 30 cm2 (0.538 sensitivity, specificity 0.584). Conclusion: There is a significant relationship between the degree of cystocele and area of the levator ani muscles when Valsava, but there is no relationship at rectocele. The value of maximum area under the curve (AUC) hiatal area of the levatorani muscle in distinguishing stage I-II and III-IV cystocele are relatively similar to rectocele stage I-II and III-IV. Optimal cut point hiatal area of the levatorani muscle in distinguishing stage I-II and III-IV cystoceleis 29 cm2, while for rectocele is 30 cm2 with sensitivity and specificity values were quite good. Keywords: cystocele, levatorani hiatal area, pelvic organ prolapse, rectocele
The Degree of Cystocele and Rectocele with Hiatal Area Levator Ani Moegni, Fernandi; Santoso, Hari
Indonesian Journal of Obstetrics and Gynecology Volume. 5, No. 4, October 2017
Publisher : Indonesian Socety of Obstetrics and Gynecology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (206.803 KB) | DOI: 10.32771/inajog.v5i4.566

Abstract

Objective: To investigate the degree of cystocele and rectocele with a maximum of levator hiatal area (AHL) during Valsava. Methods: Secondary data analysis of 90 patients with uterine prolapse January 2012 to November 2013 in the clinic Uroginekologi RSCM, Jakarta. 3D/4D ultrasound measurement and pelvic organ prolapse system Quantification (POP-Q) stage I-IV cystocele and rectocelestage I-IV. All statistical analyses were analyzed using Stata 20 for Windows. Results: Significant difference cystocele stage I-II (n = 25) with stage III-IV (n = 65), the maximum AHL with a difference of 4.33 cm2 (p = 0.040). In rectocele stage I-II (n = 64) and stage III-IV (n = 26) of 3.85 cm2 (p = 0.130). AUC values for stage I-II and III-IV cystocele was 0.607 (IK95% from 0.467 to 0.738), and the ROC for rectocele was 0.603 (IK95% from 0.472 to 0.734). The ROC optimal cut point for cystocele stage I-II with III-IV with the highestsensitivity and specificity is 29 cm2 (0.523 sensitivity, specificity 0.520), the rectocele is 30 cm2 (0.538 sensitivity, specificity 0.584). Conclusion: There is a significant relationship between the degree of cystocele and area of the levator ani muscles when Valsava, but there is no relationship at rectocele. The value of maximum area under the curve (AUC) hiatal area of the levatorani muscle in distinguishing stage I-II and III-IV cystocele are relatively similar to rectocele stage I-II and III-IV. Optimal cut point hiatal area of the levatorani muscle in distinguishing stage I-II and III-IV cystoceleis 29 cm2, while for rectocele is 30 cm2 with sensitivity and specificity values were quite good. Keywords: cystocele, levatorani hiatal area, pelvic organ prolapse, rectocele
MANAJEMEN FASILITAS DI RUANG UTAMA MASJID AL FALAH SURABAYA Ramandana, Bima; Santoso, Hari; Bramayudha, Airlangga
Masjiduna : Junal Ilmiah Stidki Ar-Rahmah Vol 3, No 1 (2020): 1-48 : Juni
Publisher : STIDKI Ar Rahmah, Surabaya

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Abstract

ABSTRACTThis study aims to determine how the management of facility utilization and maintenance of facilities in the main room of Masjid Al-Falah Darmo Surabaya. The esearch used descriptive qualitative method. The research finding is Al-Falah Mosque Surabaya prioritizes management in maintaining the stability of worship by utilizing the facilities in the main room of the mosque, The conclusion is that the management of utilization and maintenance of facilities in the main room of Al-Falah Mosque in Surabaya is very concerned and maximally utilized with a variety of religious and social activities and hospitality from the administrators and the mosque's facilities and infrastructure section to become the mosque which is very crowded and visited by worshipers.ABSTRAKPenelitian ini bertujuan untuk mengetahui bagaimana manajemen pemanfaatan fasilitas dan pemeliharaan fasilitas di ruang utama Masjid Al-Falah Darmo Surabaya. Penelitian ini menggunakan metode kualitatif deskriptif. Hasil dari penelitian ini yaitu: Masjid Al-Falah Surabaya sangat menjaga kestabilan ibadah dengan memanfaatkan fasilitas di ruang utama masjid tersebut. Kesimpulannya ialah bahwa pemanfaatan dan pemeliharaan fasilitas di ruang utama Masjid Al-Falah Surabaya sangat diperhatikan dan dimanfaatkan secara maksimal dengan berbagai kegiatan keagamaan maupun sosial serta keramahan dari para pengurus dan bagian sarana dan prasarana masjid menjadikan masjid tersebut sangat ramai dikunjungi dan didatangi oleh jama’ah.
Analisis Normalitas dan Abnormalitas Spermatozoa Segar Sapi Limousin (Bos taurus) dan Sapi Bali (Bos sondaicus) Sebelum Proses Pembekuan Di Balai Besar Inseminasi Buatan Singosari Malang Nur Aliyah, Shofi; Santoso, Hari; Zayadi, Hasan
SCISCITATIO Vol. 3 No. 1 (2022): Volume 3, Number 1, January 2022
Publisher : Universitas Kristen Duta Wacana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21460/sciscitatio.2022.31.85

Abstract

Sejak digalakkan Swasembada Sapi oleh kementrian pertanian guna mewujudkan ketahanan pangan hewani, dilakukanlah Inseminasi Buatan (IB). Langkah yang perlu diperhatikan dalam pelaksanaan IB adalah pengujian kualitas spermatozoa secara makroskopis dan mikroskopis. Tujuan penelitian ini adalah untuk menganalisis perbedaan normalitas dan abnormalitas spermatozoatozoa segar sapi limousin (Bos taurus) dan sapi bali (Bos sondaicus) sebelum proses pembekuan. Metode pengambilan sampel spermatozoatozoa ditampung menggunakan AV (Artivical Vagina), dilakukan pengamatan secara makroskopis dan mikroskopis menggunakan IVOS II untuk mengetahui presentase normalitas dan abnormalitas spermatozoatozoa. Parameter yang dihitung diantaranya, makroskopis yaitu Warna, volume, pH dan konsentrasi, normalitas, abnormalitas. Analisis yang digunakan adalah uji t test independent. Hasil dari penelitian normalitas dan abnormalitas sapi limousin dengan sapi bali menunjukkan thit = 4,42 ; ttabel = 0,025 yaitu thitung > t(0,025). maka H0 diterima, artinya dari kedua kelompok sapi tersebut kualitas spermatozoanya tidak perbedaan nyata secara signifikan antara normalitas dan abnormalitas sapi limousin dan sapi bali sebelum proses pembekuan.
Development of Web-based School Uniforms order Application in a Private School with Prototyping Model Wiratama, Jansen; Ady Sanjaya, Samuel; Santoso, Hari; Brian Kurniadi, Reinardus
International Journal of Science, Technology & Management Vol. 4 No. 6 (2023): November 2023
Publisher : Publisher Cv. Inara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46729/ijstm.v4i6.977

Abstract

Strada SMK Daan Mogot, a private school in Tangerang City, oversees several operations. Student registration, academic exams, uniform measurements, and book purchases are carried out at the beginning of each school year. The Uniform Team tasked with handling this activity experienced difficulties due to the large volume of data, making conventional techniques inefficient to carry out. This research focuses on simplifying uniform ordering procedures from the uniform team to the uniform manufacturing supplier. The Uniform Team recorded and measured orders by hand, which resulted in time-consuming management and limited real-time data monitoring for the Principal. A web-based solution that allows easy access to uniform ordering data is needed to speed up these operations. The successful development and installation of this application at SMK Strada Daan Mogot is a significant achievement, with good User Acceptance Test results and confirming alignment with user needs. This progress is an essential step toward optimizing school operations.
Comparison of Combination of TOGA and Basalt Feed as Immunomodulator ln Male Chickens Athiyyah, Ismah Ummi; Santoso, Hari; Latuconsina, Husain
Agrikan Jurnal Agribisnis Perikanan Vol. 14 No. 2 (2021): Agrikan: Jurnal Agribisnis Perikanan
Publisher : Fakultas Pertanian, Universitas Muhammadiyah Maluku Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1520.633 KB) | DOI: 10.52046/agrikan.v14i2.780

Abstract

The purpose of this study was to compare the results between the addition of TOGA combination in feed as an immunomodulator in male chickens. The research method used Factorial Design with 2 treatments namely: P1 treatment (basal feed) and P2 treatment (basal feed mixed with TOGA flour combination). The test animals used 40 roosters with an average weight of 50 g. Each treatment consisted of 20 chickens divided into two groups of 10 chickens each and performed for 30 days. Data analysis using Variety Imprint Test and Least Real Difference Test (BNT). Daily growth (DG) results P1 12.1%> P2 11%. Absolute growth (W) P1 363 g> P2 330 g. Feed consumption (FI) P1 6713.1 g> P2 6636.8 g. Mortality (D) P1 0.15 %> P2 0.0 %. Conclusions from the research results of basal feed can accelerate the growth of chickens, while the combination of TOGA is able to maintain 0 % survival compared to basal feed by 0.15 %. The benefits of giving a combination of TOGA mixed with feed are thought to be a natural immunomodulator for roosters
Co-Authors ABDUS SAMAD Ady Sanjaya, Samuel Agus Naba Ahmad Homaidi ahmad syauqi, ahmad Aisyah Wardani, Aisyah Aisyi, Dinda Rohadatul Aldri Frinaldi Amaliyah, Viki Argus Argus Athiyyah, Ismah Ummi Basyariyah, Iflahatul Bramayudha, Airlangga Brian Kurniadi, Reinardus Cifran, Cifran Evelin Johan, Monika Fauzilah, Isma Fernandi Moegni Fuadi, Muhammad Chaniful Fuadi, Mukhlisul Gea, Notatema Anugrah Hafizatul, Intani Sholihah Haq, Fafa Maulal Hasan Zayadi Hermanto Hermanto Hidayati, Arini Hizni, Alina Husain Latuconsina Ikbal, Mohammad Izajati, Mustafidah Nur Jailani, Ach Jonathan Kusmawati, Eka Lailah, Rukhil Latconsina, Husain Lesminingsih, Ratna Djuniwati Maghfirah, Inayatul Mahmudi Mahmudi Mariyana Mariyana Maulidiyah, Ni'matul Muhammad Aziz Muslim Munawaroh, Tanwirul Ningrum, Mei Ninda Ningsih, Fitriyah Nisa, Siti Rofiatun Nour Athiroh Abdoes Sjakoer Nur Aliyah, Shofi Nur Shofiyah Munawaroh, Nur Shofiyah Nurmala, Aulia Putri Puspithasari, Agustina Dwi Putra, Heru Soetanto Putri, Febrian Priska Amalia Putri, Firlina Laila Rachmawati, Rachmawati Suprayoto Ramandana, Bima Ratna Djuniwati Lisminingsih Rian Rohmah, Qudrati Saimul Laili Samuel Samuel Santo Fernandi Wijaya Setyawan, Febrianto Sholehuddin, Mohammad Sholikha alaiya, Sholikha Sugesti, Sugesti Sukiran, Nufan Muwafiq Tandika, Idris Utami, Ade Ratna Varadibbah, Hasina Warida, Mutha Wijaya, Kusuma Lestari Wiratama, Jansen Zahroh, Dea Fatimatu Zubairi, Ach. Zuliyana, Devy