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Synthesis of silver nanoparticles from coffee parasite leaf extract (Scurrulla ferruginea (Roxb. ex Jack) Danser) and potential activity as an antioxidant and anticancer Roza, Destria; Samosir, Tico Guinessha; Sari, Sri Adelila; Selly, Rini
Jurnal Pendidikan Kimia Vol. 16 No. 1 (2024): April
Publisher : Pascasarjana Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jpkim.v16i1.54145

Abstract

This study aim is to know the results of the synthesis of silver nanoparticles from quercetin and Scurrula ferruginea (Roxb. Ex Jack) danser as well as its potential as an antioxidant and anticancer. The solvent used in the maceration extraction method in this research is the polar solvent methanol. Isolation and purification of thick extract compounds from coffee parasite leaves were carried out using liquid vacuum chromatography (CVC) and gravity column chromatography (GCC) methods. Silver (Ag) nanoparticle is made with the stirrer method at a speed of 1500 rpm for 60 minutes at a temperature of 70o C. Silver nanoparticle solution was produced and then characterized using FTIR (Fourier Transform Infra Red) and PSA (Particles Size Analyzer). PSA results analysis using extract coffee parasite size 214 nm particles, whereas using flavonoid isolate quercetin confirmed size 29 nm. FTIR showed that there was a stretching vibration of the OH group at a wave number of 3229.25 cm-1, the C=O function at the wave number 1637.87 cm-1, and the CO functional group at the wave number 1016.31 cm-1. Antioxidant test using the DPPH method was carried out in silver nanoparticle solution using extract Scurrula ferruginea (Roxb. Ex Jack) danser and with quercetin obtained an IC50 value of around 115.4 and 114.9 this result describes as moderate level of antioxidants. Even though the nanoparticle anticancer test was very weak, overall, the synthesis of silver nanoparticles using flavonoid isolates was better than using extracts from coffee parasite leaves.
Development of Lectora Inspire Application-Based E-Modules on The Topic of Coloid Systems Sari, Sri Adelila; Yustika, Merry
PAEDAGOGIA Vol 26, No 2 (2023): PAEDAGOGIA Jilid 26 No 2 (2023)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/paedagogia.v26i2.72476

Abstract

The problem that often occurs during the learning process is that students feel bored and do not focus on the material taught by the teacher. Hence, students are not active during the discussion process, and these problems result in low student learning outcomes. In this case, the teacher seeks to arouse student interest and motivate students to be more enthusiastic about learning using the Lectora Inspire application-based learning media. This type of research was research and development (R&D) using the 4D model consisting of 4 stages: define, design, develop, and disseminate. The define stage was carried out by analyzing to obtain information in the field. The design was done by making an e-module design; the development stage is developing e-modules using Lectora Inspire and conducting assessments and trials. The final stage was dissemination, namely disseminating e-modules. After being validated, the research results showed that modules based on Lectora inspire applications in the colloid system course were declared feasible after being validated by material experts, media experts, teacher responses, and student responses. Assessment of material and media experts with an average percentage of 90.41% with the appropriate/valid category, the percentage of teacher responses was 84.76% with very high criteria, and the percentage of student responses was 83.54% with very high criteria. Based on the results of the n-gain score of 0.62 with a moderate category, the Lectora inspire-based e-module effectively improves learning outcomes. It can be concluded that the electronic module based on the inspirational Lectora application as an interactive learning medium effectively improves student learning at school.