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All Journal Jurnal Sains dan Seni ITS Jurnal Kedokteran Brawijaya Journal of the Medical Sciences (Berkala Ilmu Kedokteran) Jurnal Kesehatan Reproduksi Universa Medicina Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Andalas obstetrics and gynecology journal Jurnal Mnemonic Narra J Physical Therapy Journal of Indonesia Jurnal Kesehatan Masyarakat Folia Medica Indonesiana International Journal of Computing Science and Applied Mathematics-IJCSAM
Soetrisno Soetrisno
Institut Teknologi Sepuluh Nopember
Arts Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Education Health Professions Immunology & microbiology Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health

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OMPHE-VIA (Obedient Male Partner in Health-Education and Engagement for Visual Inspection with Acetic Acid Examination) Model Was Solution to Save Cervical Cancer Ferry, Ferdinal; Machmud, RIzanda; Soetrisno, Soetrisno; Bachtiar, Adang
Andalas Obstetrics And Gynecology Journal Vol. 7 No. 1 (2023)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.7.1.286-294.2023

Abstract

Background: VIA screening is very suitable for developing countries such as Indonesia, because the technique is easy, simple, low cost/cheap, high sensitivity, fast and accurate for early detection of cervical cancer. The coverage of early detection in Indonesia is <5% so that many cases of cervical cancer are found to be at an advanced stage and often cause death in women.Methods: This study uses a mix-method study approach with a sequential exploratory approach. The research was carried out sequentially with qualitative methods first (interviews and FGDs), then continued with quantitative methods. In this study, the sampling technique used was multi-stage random sampling in 7 selected sub-districts.Results: The variable perception of vulnerability with a good perception of vulnerability have a 2.64 times greater risk of carrying out an VIA examination. In multivariate modeling, knowledge is the most dominant variable because it has the largest POR of 6.3, which means the N-Gain value is in the medium category with a fairly effective interpretation of the effectiveness of the module, namely an increase in knowledge of 63.86% after being given education using the OMPHE-VIA module. Conclusion: Based on the implementation of the OMPHE-VIA module, it was found that there was an increase in the average value of knowledge, before and after the education was given. It was also found that there was a significant difference in knowledge, and husband's support, construct between before and after the education was given using the OMPHE-VIA module.
The Influence of Psychocurative on Cortisol Level, Anxiety, and Quality of Life in Advanced Stage Cervical Cancer Patients Soetrisno, Soetrisno; Mulyani, Sri; Nurinasari, Hafi; Nurinasari, Hafi; Budi, Erindra
Folia Medica Indonesiana Vol. 55, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Every year, there are 500.000 new cases and more than 250.000 deaths caused by cervical cancerworldwide. Cervical cancer patients faced physical and psychological problems several times that it activate stress mechanism such as hypothalamus-pituitary-adrenal (HPA) axis. These recurrent activations caused HPA axis disruption and adverse clinical effects. Several symptoms of endocrine stress response are the change of circadian cortisol rhythm. Cortisol is known as a stress hormone that involves an organism's response to stress and anxiety that influence the quality of life. This research aims to analyze the differences among serum cortisol level, anxiety, and quality of life in cervical cancer patients before and after psychocurative intervention in obstetrics and gynecology wards and polyclinic in RSUD Dr. Moewardi Surakarta. This research is an experimental double-blind randomized controlled clinical trial pre-test post-test group design study. The subjects were advance stage (IIB-IV)cervical cancer patients. The subjects were randomly chosen into fifteen subjects that given standard therapy and psychocurative, while the other fifteen subjects as a control only got standard therapy. Data were obtained from measurement of serum cortisol level, anxiety questionnaire DASS 42 and WHO quality of life questionnaire. Data were analyzed using SPSS 21 using difference test. The difference mean test result of cortisol serum level, anxiety, quality of life from the controlled group and uncontrolled group showed a significant difference (p < 0.05). In conclusion, psychocurative is significant to reduce cortisol level, anxiety, and improve the quality of life in advanced stage cervical cancer patients.
The effect of recombinant vascular endothelial growth factor 121 on nitride oxide level in mice (mus musculus) model of preeclampsia Soetrisno, Soetrisno; Isharyadi, Isharyadi; Sulistyowati, Sri
Folia Medica Indonesiana Vol. 53, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Preeclampsia is a multifactorial syndrome in pregnancy whose cause is still unknown. Several proangiogenic and antiangiogenic mediators such as Vascular Endothelial Growth Factor (VEGF) and Nitrite Oxide (NO) play important roles in preventing preeclampsia. VEGF can increase NO level that lowers maternal blood pressure, improves endothelial function and reduces placental hypoxia in preeclampsia. Recombinant VEGF 121 is expected to be an option in the prevention and treatment of preeclampsia. This experimental study used mice (Mus musculus) as the model. The objective of this study was to observe the effect of recombinant VEGF 121 in increasing the level of nitric oxide in mice (Mus musculus) model of preeclampsia. This was an experimental analytical study with Randomized Control Trial (RCT) design. The study enrolled 27 pregnant mice (Mus musculus) which met the restriction criteria divided into 3 groups. The first group (K1) were 9 normal pregnant mice. The second group (K2) were 9 pregnant mice of preeclampsia model without treatment. The third group (K3) were 9 pregnant mice of preeclampsia model receiving recombinant VEGF 121 therapy. The independent variable was the administration of recombinant VEGF 121 and the dependent variable was the serum NO level. Statistical analysis was performed by using anova statistics. NO level in the first group (K1) was 1.746±0.347, with minimum value of 1.00 µM, and maximum value of 2.28 µM, CI (1.479-2.013). NO level in second group (K2) was 1.167±0.380, with minimum value of 0.64 µM, and maximum value of 1.94 µM, CI (0.875-1.460). NO level in the third group (K3) was 2.164±0.556, with minimum value of 1.56 µM, and maximum value of 5.96 µM, CI (1.842-2.486). With anova statistical test, there were significant differences between K1 group and K2 group (p value=0.004<0.05), K1 group and K3 group (p value=0.000<0.05) as well as K2 group and K3 group (p value=0.029<0.05). In conclusion, Recombinant VEGF 121 increased the level of nitric oxide in mice (Mus musculus) model of preeclampsia significantly.
The impacts of stimulation in protracted labor to cortisol levels and incidence of post-partum blues Soetrisno, Soetrisno; Respati, Supriyadi Hari; Sulistyowati, Sri; Kurniawan, Hendro
Folia Medica Indonesiana Vol. 53, No. 1
Publisher : Folia Medica Indonesiana

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Abstract

Delivery, induction, stimulation, cesarean section with the aid of a vacuum extraction, for example, can reduce maternal confidence on the smooth delivery process, as well as improve postpartum stress. These stressors stimulate the HPA axis (hypothalamus-pituitary-adrenal), so that the adrenal cortex produces more cortisol hormone, it can increase postpartum blues. The objective of this study was to analyze the effect of delivery stimulation on protracted labor on cortisol levels and the occurrence of postpartum baby blues. This was an experimental study of non-randomized post-test control group. The subject of the study 30 patients in labor taken consecutive sampling, divided into 2 groups (normal delivery and stimulation) each group consist of 15 patients. In stimulation delivery group, it is examined of cortisol serum levels after five days and then continued for postpartum blues occurrence measurement. Statistical analysis using t-test for differences in levels of cortisol and chi square for analyzing the effect on the occurrence of post-partum blues (a=0.05). Mean level of cortisol in delivery stimulation group is 40.29 ± 5.58, in normal delivery is 33.59 ± 11.17, with p=0.047, meaning there are significant differences both study groups. Stimulation delivery increases the occurrence of post-partum blues 5.50 times compared to normal delivery (OR=5.50 and p=0.028). Mean cortisol levels on post-partum blues higher at 42.90 ± 6.97 compared to no post-partum blues 30.14 ± 6.66, p=0:00, which means there are significant differences both groups. In conclusion, there was significant relationship between stimulation in protrated labor that increases cortisol serum level and post partum blues incidence.
Expression of human leukocyte antigen-e and natural killer cells in intra uterine fetal death Sulistyowati, Sri; Nugroho, Muhammad Anggit; Respati, Supriyadi Hari; Soetrisno, Soetrisno
Folia Medica Indonesiana Vol. 53, No. 4
Publisher : Folia Medica Indonesiana

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Abstract

Intra Uterine Fetal Death (IUFD) is one contributor to infant mortality. Human Leukocyte Antigen-E (HLA-E) and Natural Killer Cells (NK cells) are believed to play an important role towards IUFD associated with immune maladaptation. This study aimed to determine the expression of HLA-E and NK cells on trophoblast on IUFD and normal pregnancy. The study used cross sectional approach undertaken at Department of Obstetrics and Gynecology, Dr. Moewardi Hospital, Surakarta, networking hospitals, and Anatomic Pathology Laboratory of Faculty of Medicine, Sebelas Maret University. The number of samples were 32 subjects consisting of 16 subjects with normal pregnancy and 16 subjects with IUFD. The expression of HLA-E and NK cells on trophoblast of subjects who met the inclusion and exclusion criteria were examined using immunohistochemistry method and t-test statistical analysis. The mean value of HLA-E expression in the trophoblast of IUFD group was 17.30±6.69, in normal pregnancy was 57.06±32.04, with p=0.00 (p<0.05). The mean value of NK cell expression in trophoblast in IUFD group was 78.62±36.43, in normal pregnancy was 19.87±6.43, with p=0.00 (p<0.05). This study concluded that the expression of HLA-E was lower and NK cells wass higher in IUFD compared to those in normal pregnancy.
Effect of cognitive behavioral therapy for serotonin level, depression score and quality of life in cervical cancer patients Soetrisno, Soetrisno; Sulistyowati, Sri; Respati, Supriyadi Hari; Nasrudin, Muhamad
Folia Medica Indonesiana Vol. 52, No. 3
Publisher : Folia Medica Indonesiana

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Abstract

Cervical cancer is the most common cause of death among gynaecological neoplasms. Management of advanced cervical cancer currently has not been able to improve the prognosis. Standard intervention therapy, chemotherapy and radiotherapy, as well as the emerging pain could lead to psychological stress till depression, thus reduce patients' quality of life. CBT for psychological stress and depression is expected to improve the fruitfulness of standard therapy. Serotonin is a neurotransmitter which plays a role in the patophysiology of depression. The aim of this study is to analyze the effect of cognitive behavioral therapy on serotonin level, depression score and quality of life in advanced cervical cancer patient with experimental quasi pre and post test design methods. The samples are 15 subjects in both intervention and control groups. Intervention group was given CBT and standard therapy, while control group was given standard therapy only. Study was held in Department of Obstetric and Gynecologic Dr. Moewardi Hospital Surakarta and Prodia Laboratory, in January to March 2015. Independent variable was advanced cervical cancer patients underwent CBT intervention and dependent variables were serotonin level, depression score and quality of life score. The result, serotonin level and quality of life scores were higher after intervention compared with control, (219.43±33,42 vs 89.57±23.23) and (85.13±14.62 vs 41.86±7.24), respectively. Depression score was lower after intervention than without CBT intervention (11.20±4.94 vs 17.00±4.86) and statistically significant (p < 0.05). So, there were effects of cognitive behavioural therapy on serotonin level, depression score and quality of life score in cervical cancer patients and were statistically significant.
Texture-Based Woven Image Classification using Fuzzy C-Means Algorithm Soetrisno Soetrisno; Dwi Ratna Sulistyaningrum; Isi Bifawa’idati
(IJCSAM) International Journal of Computing Science and Applied Mathematics Vol. 8 No. 1 (2022)
Publisher : LPPM Institut Teknologi Sepuluh Nopember

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Abstract

There are a lot of texture-based image data stored in the storage media Internet. Most of these data portray the cultural fabric texture results from a State. Because of the many variants of the existing texture, the data need to be easily accessible through the Internet. Moreover, the area of origin of weaving the surface is easily known. Therefore, it is necessary to develop a classification system based on woven image data. The texture of the image data stored in a database on the Internet can be grouped/clustered well, making it easy to access. This study examines a texture-based woven image classification using fuzzy c-means algorithm. This method combines extraction methods Gabor filter, fuzzy c-means algorithm and Euclid distance similarity measure. An experiment was done using the system as many as 60 woven images from Bali, NTT and Central Java areas, each taken as many as 25 images weaving. The test results stated that testing using the test images taken from the images in the database generates a 100% accuracy rate, and testing using test images taken from outside the database produces an accuracy rate of 94%.
A Genetic Algorithm with Best Combination Operator for the Traveling Salesman Problem Muhammad Luthfi Shahab; Titin J. Ambarwati; Soetrisno Soetrisno; Mohammad Isa Irawan
(IJCSAM) International Journal of Computing Science and Applied Mathematics Vol. 5 No. 2 (2019)
Publisher : LPPM Institut Teknologi Sepuluh Nopember

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Abstract

In this research, we propose a genetic algorithm with best combination operator (BC(x,y)O) for the traveling salesman problem. The idea of best combination operator is to find the best combination of some disjoint sub-solutions (also the reverse of sub-solutions) from some known solutions. We use BC(2,1)O together with a genetic algorithm. The proposed genetic algorithm uses the swap mutation operator and elitism replacement with filtration for faster computational time. We compare the performances of GA (genetic algorithm without BC(2,1)O), IABC(2,1)O (iterative approach of BC(2,1)O), and GABC(2,1)O (genetic algorithm with BC(2,1)O). We have tested GA, IABC(2,1)O, and GABC(2,1)O three times and pick the best solution on 50 problems from TSPLIB. From those 50 problems, the average of the accuracy from GA, IABC(2,1)O, and GABC(2,1)O are 65.12%, 94.21%, and 99.82% respectively.
Co-Authors Abd. Rasyid Syamsuri Adang Bachtiar Adang Muhammad Gugun, Adang Muhammad Agus Kristiyanto Ambar Mudigdo Anwar Sandi Wibowo, Anwar Sandi Asrial, An A. Bambang Eko Wiyono, Bambang Eko Bambang Purwanto Brian Wasita Budi, Erindra Cahyanto, Erindra Budi Didon Muhammad Trimulya Donny Irawan, Donny Dono Indarto Dwi Ratna Sulistyaningrum Eddy Tiro Eric Edwin Yuliantara Eti Poncorini Pamungkasari Fadhlan Septianto Eka Putra Faris, Abdul Ferry, Ferdinal Fitriana Fitriana Hari Wujoso Harsono Salimo Ida Nurwati Imam Mukhlash Isharyadi, Isharyadi Isi Bifawa’idati John Arianto Sondakh, John Arianto Kurniawan, Hendro Laqif, Abdurahman Laqif, Abdurrahman Laras Binarwati Mappaware, Nasrudin Andi Mohammad Hakimi Mohammad Isa Irawan Muchsin Doewes Nasrudin, Muhamad Nizar Hero K, Nizar Hero Nugroho, Anung N. Nugroho, Muhammad Anggit Nur Shani Meida Nurinasari, Hafi Ova Emilia Pamungkasari, Eti P. Pudjiastuti, Anggit Rabrageri, Alberthzon Kris Silo Rahmah Rahmah Reviono Reviono Rifdy Fachry Risanto Siswosudarmo Risya Cilmiaty, Risya Rizanda Machmud Senyum Indrakila Setianto, Budi Y. Shahab, Muhammad Luthfi Soerjo Hadijono Sri Mulyani Sri Sulistyowati Sulistyawati, Sri Sulistyawati, Sri Supriyadi H Respati Supriyadi Hari Respati Suryoningrat, Dewanto Syamsiar, Syamsiar Syetiawinanda, Amriansyah Titin J. Ambarwati Tjiang, Rubin Enhui Tonang Dwi Ardyanto Trimulya, Didon M Umar Malinta Vitri Widyaningsih Wulandari, Eka T. Yarso, Kristanto Y. Yusup Subagio Zaidah, Lailatuz Zulfa Afiq Fikriya