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Identifikasi Drug Related Problems (DRPs) Pada Pasien Penyakit Ginjal Kronis di Instalasi Rawat Inap Rumah Sakit X Surakarta Tahun 2024 Afrizal Mubarok; Tista Ayu Fortuna
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 4 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i4.1075

Abstract

Background: Chronic kidney disease (CKD) is a condition characterized by impaired kidney function lasting at least three months. In patients with chronic kidney failure, the use of multiple medications has the potential to increase the risk of drug-related problems (DRPs), which can hinder the expected effectiveness of therapy. Objective: This study aims to determine the incidence of DRPs in patients with chronic kidney disease treated at the inpatient facility of Hospital X in Surakarta. Methods: This study employed a cross-sectional methodology and a non-experimental design. Data were collected retrospectively through the medical records of patients with chronic kidney disease treated at the inpatient facility of Hospital X in Surakarta. Data analysis was performed univariately by describing and analyzing the study variables. DRPs were identified based on the Pharmaceutical Care Network Europe (PCNE) classification. Results: The most common comorbidity was anemia at 27.93%, while the most frequently used drug class was vitamins and minerals at 24.70%. Of the 108 patients analyzed, 12 patients experienced at least one DRP (11.11%). In total, 15 cases of DRPs were identified with code P1.3 (problem) and codes C3.1, C3.2, C3.3, and C3.4 (causes) from those 12 patients. Conclusion: This study shows the occurrence of DRPs in patients with chronic kidney disease treated at Hospital X in Surakarta.
The Relationship Between Rational Antibiotic Use and Theurapeutic Outcomes in Patients with Community Acquired Pneumonia Tista Ayu Fortuna; Filla Rizky Nuraini; Hidayah Karuniawati
Pharmacon: Jurnal Farmasi Indonesia Vol. 22 No. 1 (2025)
Publisher : Universitas Muhammadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/pharmacon.v22i1.11678

Abstract

Pneumonia is an infection caused by microorganisms. Antibiotics are one of the treatments given to patients with pneumonia caused by bacterial infections. Rational use of antibiotics will prevent resistance. This study aims to determine the relationship between the rationality of antibiotic use and therapeutic outcomes in community-acquired pneumonia patients. We used a cross-sectional study and retrospectively collected data using purposive sampling. The inclusion criteria are non-ICU community pneumonia patients have complete medical record data, while the exclusion criteria are patients who died or had other infections. We evaluated the rationality of antibiotics using the Gyssens method. Based on the results, there are 240 patients, with 210 patients receiving rational therapy and 30 patients receiving irrational antibiotics. Based on the results, 6 patients did not receive antibiotics on time, 4 patients received the wrong dose, 2 patients did not get the correct interval, 16 patients received a dose that was too short, and 2 patients were prescribed alternative antibiotics that were more effective. The results of the analysis showed that there is a significant relationship between the rationality of antibiotic use and the therapeutic outcomes of community-acquired pneumonia patients (p-value < 0.001; OR 14.36).
Co-Authors A Anifatussaa'dah Adedhea, Marchita Aflit Nuryulia Praswati Afrizal Mubarok Ahmad, Farhand Aisya, Fitria Shofwa Andi Suhendi Andriyani, Refi Anggi Fajriatu Hidaya Anifatussaa'dah, A Ardalia Rinanda Oktaviani Arifah Sri Wahyuni Ariyanti, Rika Auliya, Dhiyahul Azzah, Millenia Syafirah Yunita Basusena, Rahardian Surya Broto Santoso Burhanudin Ichsan Citra, Tia Mella Davina Lathifah Nuraini Desti Purnamasari Devi Etivia Purlinda Dewi, Triana Ariska Didik Hasmono Dina Yuli Astuti Dwi Sarbini Dzafira, Laila Erna Herawati Erna Herawati, Erna Faghfirlie, Faghfirlie Fahriza Mei Trihatmoko Faridita khoirun Nisa' Fidhia Nur Rifaini Filla Rizky Nuraini Firdani, Tamza Aulia Nerisa Fita Rahmawati Fitriani Rizki Ainun Fitriani, Rizki Ainun Haliza Arzeti Nurseptiria Haryoto Haryoto Haryoto, H Haya Nabilah Utama HI, Marsilia Rosa Sinensis Hidajah Rachmawati Hidayah Karuniawati Ichsan, Burhanudin Ida Maesaroh Ida Maesaroh, Ida Keisya, Aulita Khusnul Khotimah khusnul khotimah Kusumastuti, Lina Ayu Laila Dzafira Lina Ayu Kusumastuti Listiana Masyita Dewi Maharani, Suciana Mariska Sri Harlianti Marisya Affifah Putri, Nabilla Marsilia Rosa Sinensis HI Marsya, Vitania Mudhofir, Nisrina Salsabila Muhtadi Muhtadi Muhtadi, M Mulyani, Amelia Sri Muslihah, Sayyidah Nurul Nabilla Marisya Affifah Putri Nadya Tiara Putri Nanang Munif Yasin Nanang Munif Yasin Nandifa Azzahra Salsabila Ni Nyoman Yudianti Mendra Nikita, Aulia Bea Nisa', Faridita khoirun Nurseptiria, Haliza Arzeti Oktaviani, Ardalia Rinanda Prabowo, Alifia Istiqomah Prehanawan, Refian Putra Raafika Studiviani Rahardian Surya Basusena Rahmawati, Fita Ramadhini, Affida Rayidah, Tasya Refi Andriyani Renatasari, Distya Ayu Rifaini, Fidhia Nur Riskiana, Shafira Yuni Rizki Ainun Fitriani Safitri, Aisyah Nur Saputri, Gafrila Fani Eka Sarif, Nabil Nawal Sasmitha, Desya Sayyidah Nurul Muslihah Sri Kusuma Dewi Studiviani, Raafika Sulistyani Sulistyani Syahidah, Shofia Rif'atusy Tanti Azizah Sujono Tia Mella Citra Trihatmoko, Fahriza Mei Utama, Haya Nabilah Utami , Anita Dwi Utari, Berlian Vitania Marsya Yudianti Mendra, Ni Nyoman