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All Journal Jurnal Gizi dan Pangan Sari Pediatri Paediatrica Indonesiana JURNAL PENDIDIKAN JASMANI DAN OLAHRAGA AcTion: Aceh Nutrition Journal Contagion: Scientific Periodical Journal of Public Health and Coastal Health Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia World Nutrition Journal Jurnal Prima Medika Sains Journal of Community Empowerment for Health IJCNP (INDONESIAN JOURNAL OF CLINICAL NUTRITION PHYSICIAN) Archives of The Medicine and Case Reports Cermin Dunia Kedokteran Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Sehat Indonesia (JUSINDO) Jurnal Penyakit Dalam Indonesia Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute Cermin Dunia Kedokteran
Diana Sunardi
Departemen Ilmu Gizi Fakultas Kedokteran Universitas Indonesia Indonesian Hydration Working Group - FKUI
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Veterinary

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The Role of Eicosapentaenoic Acid Supplementation on Muscle Mass in Malnutrition Patients with Squamous Cell Carcinoma of the Tongue: Case Report Kirana, Annisa Nurul; Sunardi, Diana; Manikam, Nurul Ratna Mutu; Rasyid, Nurhayati M
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 7 No. - (2023): Proceedings Book of International Conference and Exhibition on The Indonesian M
Publisher : Writing Center IMERI FMUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69951/proceedingsbookoficeonimeri.v7i-.195

Abstract

The Indonesian prevalence of lip and oral cavity cancer in 2020 was 14,913, with 5,780 new cases. Head and neck cancer patients are very vulnerable to malnutrition; about 50% are malnourished, and 80% experience unwanted weight loss. Studies showed a significant effect of EPA as an anti-inflammatory substance. A 56-year-old female patient with a diagnosis of tongue squamous cell carcinoma (SCC) presents with the tumor removed along with some teeth. She is experiencing difficulty chewing food and had a weight loss of 8 kg (17%) in the last six months. The patient's muscle mass was 25.5% (low). Patients were given protein intake in the 1.1-1.8 g/kgbw/day range and EPA supplementation of 1.1 g/day. After one month, the BIA measurement showed that her muscle mass had increased to 26.2% and was in the normal category. Omega 3, especially EPA, improved body weight and lean body mass in cancer patients by modulating circulating inflammatory markers, demonstrating an inhibitory effect on inflammatory parameters related to muscle atrophy and lipolysis.Adequate protein intake and supplementation of 1.1 g/day EPA increased muscle mass in malnourished patients and enhanced the effectiveness of cancer therapy.
Co-Authors Achmad Mulawarman Jayusman Adelina Haryono Afifa, Nadhira Nuraini Ali Sungkar Ali Sungkar Almira Devina Anak Agung Eka Widya Saraswati Andayani, Diyah Eka Andry Kelvianto Angelia, Wella Anin Ika Rosa Ardesy Melizah Kurniati arieska felicia Audy Alexander, Ruth Ayu Diandra Sari Ayu Diandra Sari Badriul Hegar Bernie Endyarni Medise Budi Wiweko Budiati Sutanto, Luciana C Rinaldi A Lesmana Chandra, Dian Novita Christy, Sarah claresta diella Dadang Makmun Devina, Almira Dewi Friska Dian Araminta Ramadhania Dian Araminta Ramadhania Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Dian Sarah Mutiara Diyah Eka Andayani Diyah Eka Andayani Diyah Eka Andayani Dwi Nastiti Iswarawanti Dwirini Retno Gunarti Dyah Arum Kusumaningtyas E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Erfi Prafiantini Ervira Wahyuni Esthika Dewiasty Esthika Dewiasty Esthika Dewiasty Evania Astella Setiawan Evania Astella Setiawan Fadilah Fadilah, Fadilah Fransisca Olivia Gabriella Nurahmani Putri Gloriana Seran Godong, Bernardine Handayani Eka Puspita Sari Hasan Maulahela, Hasan Helda Khusun Ikhwan Rinaldi Iwan Surjadi Handoko Jessica Ferdi Juferdy Kurniawan Karin Wiradarma Kirana, Annisa Nurul Krisadelfa Sutanto Krisadelfa Sutanto Luana Lidwina Marvin Marino Mauluddy, Anggita Citra Resmi Melyarna Putri Mulianah Daya Muningtya Philiyanisa Alam Nathania, Maggie Neng Tine Kartinah Almuktabar Ninik Mudjihartini Noorwati Sutandyo Novi Silvia Hardiany Nurhayati M Rasyid Nurul Ratna Manikam Nurul Ratna Mutu Manikam Patricia Amanda Pauline Octaviani Prajna Adhityarani Purwantini, Dian Purwita Wijaya Laksmi Putri Novia Choiri Insani Rachmawati, Dessy Suci Rahmita, Kartika Soka Raphael Kosasih Rasyid, Nurhayati M Ratih, Mia Puspita Ratnayani Reisa Melisa Wijaya Rini Sekartini Rizki Yusrini Pohan Rudy Hidayat Ruth Audy Alexander Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Saptawati Bardosono Sepmeitutu, Iwandheny Shabrina, Arifah Sheena R. Angelia Stefani, Shiela Steffi Sonia Surjadi Handoko, Iwan Sutanto, Krisadelfa Tarigan, Ananda Putri Tiara Aninditha Titis Prawitasari, Titis Triyanta Yuli Pramana Wella Angelia Wicaksari, Sifa Aulia Wiji Lestari Wiji Lestari Wina Sinaga Wina Sinaga Witjaksono, Firisha Virgidewi Wulandari, Yohannessa Yosua Y Kristian Yosua Yan Kristian Yulhasri Yulhasri Yulianti Wibowo, Yulianti