Claim Missing Document
Check
Articles

Found 29 Documents
Search

POTENSI EKSTRAK AIR DAUN PACAR CINA (Aglaia odorata) SEBAGAI BIOLARVASIDA TERHADAP LARVA Aedes aegypti Eka Siswanto Syamsul; Dwi Lestari; Siti Heldyana
PROSIDING SEMINAR KIMIA SEMINAR NASIONAL KIMIA 2013
Publisher : PROSIDING SEMINAR KIMIA

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Biolarvasida adalah suatu larvasida yang bahan-bahannya didapat dari tumbuhan yang mengandung bahan kimia (bioaktif) yang toksik terhadap larva nyamuk Aedes aegypti namun mudah terurai (terdegradasi) di alam sehingga tidak mencemari lingkungan dan relatif aman bagi manusia. Pacar cina (Aglaia ordorata) memiliki kandungan bahan aktif minyak atsiri, alkaloid, flavonoid, dan saponin yang diduga dapat digunakan sebagai biolarvasida. Penelitian ini bertujuan untuk mengetahui potensi ekstrak air daun pacar cina sebagai biolarvasida serta untuk mengetahui kadar ekstrak air yang berkhasiat sebagai biolarvasida.Metode yang digunakan adalah metode ekperimental dengan menggunakan sampel larva Aedes aegypti yang telah mencapai instar III/IV. Pembuatan ekstrak daun pacar cina menggunakan pelarut air. Pengujian aktifitas biolarvasida dibagi menjadi 6 kelompok uji yaitu kontrol positif (bubuk abate), kontrol negatif (air), ekstrak air daun pacar cina konsentrasi 62,5 ppm, 125 ppm, 250 ppm, dan 500 ppm. Perhitungan LC 50 ekstrak air daun pacar cina dengan menggunakan analisa probit Miller-Tainner. Hasil penelitian menunjukan ekstrak air daun pacar cina 62,5 ppm (30%), 125 ppm (50%), 250 ppm (70%), 500 ppm (90%), kontrol positif (100%), dan kontrol negatif (0%) dalam waktu 24 jam pengamatan. Ekstrak daun pacar cina berpotensi sebagai biolarvasida dengan nilai LC50 sebesar 123,31 ppm.
Karakterisasi Simplisia dan Uji Aktivitas Antioksidan Ekstrak dan Fraksi Daun Pidada Merah (Sonneratia caseolaris L): Characterization and Evaluation of Antioxidant Activity of Red Pidada Leaves (Sonneratia caseolaris L) Eka Siswanto Syamsul; Supomo; Siti Jubaidah
KOVALEN: Jurnal Riset Kimia Vol. 6 No. 3 (2020): Edisi Desember
Publisher : Chemistry Department, Mathematics and Natural Science Faculty, Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/kovalen.2020.v6.i3.15319

Abstract

Research on red Pidada leaves (Sonneratia caseolaris L.) which is a mangrove plant with antioxidant potential has been carried out. This study aims to determine the simplicia characterization and activity of red Pidada leaf extracts and fractions as antioxidants. The results of the simplicia characterization were: water-soluble extract content of 11%, ethanol-soluble extract content of 16%, water content of 9%, ash content of 8.17%, and acid insoluble ash content of 0.48%. The antioxidant activity test was carried out using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The antioxidant activity was determined by the IC50 (Inhibition Concentration) value. The results showed that the ethanol extract had an IC50 value of 24.22 ppm (very strong), n-hexane fraction 88.18 ppm (strong), ethyl acetate fraction 15.39 ppm (very strong), and ethanol fraction 38.41 ppm (very strong) Keywords: Sonneratia caseolaris L., antioxidants, DPPH, IC50
UJI AKTIVITAS PERASAN BUAH MENTIMUN (Cucumis sativus L) SEBAGAI BIOLARVASIDA TERHADAP LARVA NYAMUK Aedes aegypti L Eka Siswanto Syamsul; Eka Novitasari Purwanto
JURNAL KIMIA MULAWARMAN Vol 11 No 2 (2014)
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Demam Berdarah Dengue (Dengue Hemorragic Fever/DHF) merupakan penyakit infeksi yang disebabkan oleh virus dengue dengan manifestasi klinis demam, nyeri otot, dan nyeri sendi yang disertai leukopenia, ruam, limfadenopati, dan trombositopenia. Penularan infeksi virus dengue terjadi melalui vektor nyamuk genus Aedes sp. Menurut penelitian yang dilakukan oleh laeliyatun dkk (2006) buah mentimun diduga mengandung senyawa saponin dan alkaloid sehingga dapat digunakan sebagai larvasida. Penelitian ini bertujuan untuk mengetahui aktivitas larvasida perasan buah mentimun terhadap larva Aedes aegypti. Perasan buah mentimun dibuat dengan cara memeras sari buahnya. Konsentrasi sediaan uji yang digunakan yaitu 10, 20, 40, dan 80% (v/v). Pengujian larvasida dilakukan dengan cara memasukkan 10 ekor larva instar III dan IV awal ke dalam perasan buah mentimun, kontrol positif berupa abate konsentrasi 10, 20, 40, dan 60% (b/v) sebagai kontrol positif dan air PDAM adalah kontrol negatif. Perlakuan didiamkan selama 24 jam dan diamati jumlah larva yang mati kemudian dilakukan replikasi sebanyak 2 kali. Hasil perhitungan nilai LC50 dari perasan buah mentimun sebesar 43,06 dengan menggunakan metode analisis perhitungan Probit Miller - Tainner. Hal ini menunjukkan bahwa perasan buah mentimun memiliki aktivitas sebagai larvasida. Kata Kunci: Buah Mentimun, Biolarvasida, Larva Nyamuk Aedes aegypti L
IDENTIFIKASI RHODAMIN B PADA SAUS TOMAT YANG BEREDAR DI PASAR PAGI SAMARINDA Eka Siswanto Syamsul; Reny Nur Mulyani; Siti Jubaidah
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 3 No 1 (2018): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (47.698 KB) | DOI: 10.36387/jiis.v3i1.143

Abstract

Rhodamin B merupakan suatu pewarna sintetik berbentuk serbuk berwarna hijau yang digunakan sebagai pewarna tekstil dan sering digunakan untuk mewarnai suatu produk makanan, khususnya saus tomat. Saus tomat yang dijadikan sampel di Pasar Pagi Samarinda sebanyak 5 sampel. Penelitian ini menggunakan uji reaksi warna dan metode KLT. Hasil penelitian menggunakan uji reaksi warna menunjukkan bahwa sampel tidak mengandung pewarna sintetik rhodamin B. Hasil identifikasi dengan kromatografi lapis tipis diperoleh nilai Rf sampel A 0,46, sampel B 0,46, sampel C 0,4, sampel D 0,5 dan sampel E 0,78, nilai Rf baku rhodamin B 0,8. Dari nilai Rf tersebut sampel E mengandung rhodamin B karena warna bercak sampel dan rhodamin B sama yaitu berwarna merah muda dan selisih nilai Rf berada dikisaran ± 0,02 dari Rf baku.
KARAKTERISASI PARAMETER SPESIFIK DAN PARAMETER NON SPESIFIK AKAR KUNING (Fibraurea tinctoria) Supomo Supomo; Hayatus Sa`adah; Eka Siswanto Syamsul; Kintoko Kintoko; Hardi Astuti Witasari
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 5 No 2 (2020): JIIS
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (611.786 KB) | DOI: 10.36387/jiis.v5i2.592

Abstract

One of the secondary metabolites from yellow root (Fibraurea tinctoria) that has the potential to be developed as medicine is berberine. Alkaloid class compounds are reported to have antimicrobial, anti-diarrheal, intestinal parasite infection inhibitors, antihypertensives, anti-tumor, anti-inflammatory, hepatoprotective, antimalarial and anticancer properties. In the development of natural ingredients as medicine, it is necessary to standardize simplicia and extracts The research objective was to determine the characterization of specific and non-specific parameters of yellow root plants. This research is an experimental research. The object of research used yellow roots obtained from KDKT Samboja, Kutai Kartanegara district, East Kalimantan Province. Samples were made of simplicia which were extracted using the maceration method with 70% ethanol solvent. The results of the extraction were carried out by characterization including: macroscopic, microscopic, water content, water-soluble extract, ethanol-soluble extract, ash content, and acid-insoluble ash, then phytochemical screening was carried out. Data were analyzed using descriptive methods. The results of macroscopic characterization of yellow root simplicia powder were Liana with a length of 10-20 m, with round stems, bark grayish brown, coarse, 2-7 cm in diameter and bright yellow powder color. The simplicia powder microscopy found stone cell fragments and tracheal fragments. Characterization of simplicia powder, water content of 67.3%, ethanol soluble extract content of 6.69%, water soluble extract content of 8.05%, ash content of 7.37%, acid insoluble ash content of 0.37%. The results of the identification of the chemical compound group were positive for containing chemical compounds in the form of alkaloids, flavonoids and saponins.
Uji Aktivitas Antibakteri EkstrakEtanol dan Fraksi Batang Kuning (Fibraurea Tinctoria Lour) terhadap Bakteri Escherichia coli dan Staphylococcus aureus Lusi Mardika Ariyanti; Supomo Supomo; Hayatus Sa’adah; Eka Siswanto Syamsul; Kintoko Kintoko; Hardi Astuti Witasari
JI-KES (Jurnal Ilmu Kesehatan) Vol 5, No 2 (2022): JI-KES (Jurnal Ilmu Kesehatan)
Publisher : STIKes Hafshawaty Pesantren Zainul Hasan Probolinggo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33006/ji-kes.v5i2.323

Abstract

Abstrak Akar kuning (Fibraurea tinctoria Lour) merupakan tumbuhan khas yang dapat dijumpai di Kalimantan serta biasa dimanfaatkan oleh masyarakat setempat sebagai obat gatal, penyakit kuning dan diare. Salah satu senyawa kimia yang terkandung dalam akar kuning adalah berberin yang berpotensi memiliki khasiat sebagai antidiabetes, antivirus, antibakteri dan antiinflamasi. Penelitian ini bertujuan untuk  mengetahui potensi tumbuhan Akar Kuning (Fibraurea tinctoria Lour.) sebagai antibakteri terhadap bakteri Escherichia coli dan Staphylococcus aureus dengan menggunakan metode disc diffusion. Ekstrak etanol difraksinasi dengan menggunakan pelarut n-heksan dan etilasetat, ekstrak dan fraksi yang telah didapat ditimbang dengan konsentrasi 2,5%, 5% dan 10%. Kontrol positif yang digunakan yaitu amoxicillin dan DMSO sebagai kontrol negatif. Hasil penelitian menunjukkan bahwa ektrak etanol dan fraksi akar kuning (Fibraurea tinctoria Lour.) memiliki potensi untuk menghambat pertumbuhan bakteri. Aktivitas zona hambat terbesar yang terbentuk pada ekstrak etanol yaitu pada konsentrasi 10% dengan diameter zona hambat 9,18 mm terhadap bakteri Escherichia coli dan 12,16 mm terhadap bakteri Staphylococcus aureus sedangkan fraksi batang akar kuning yang memiliki aktivitas antibakteri paling kuat terhadap bakteri Escherichia coli dan Staphylococcus aureus yaitu fraksi sisa. Staphylococcus aureus memiliki sensitifitas lebih tinggi terhadap akar kuning (Fibraurea tinctoria Lour) dari pada bakteri Escherichia coli. Kata kunci  : antibakteri, akar kuning, berberin, Fibraurea tinctoria Lour. Abstract Akar kuning (Fibraurea tinctoria Lour.) is typically plant that can be found in Kalimantan usually used by local people as itch medicine, jaundice and diarrhea. Berberin, one of the chemical compounds contained in the akar kuning, berberin has the potential to act as an anti-diabetic, antiviral, antibacterial, and anti-inflammatory. This study aimed to determine the activity of akar kuning as an antibacterial against Escherichia coli and Staphylococcus aureus using the disc diffusion method. Ethanol extract are fractionated using n-Heksan and Etilasetat solvents, the obtained of extract and fraction are weighed to 2,5%, 5% and 10%. Positive control antibacterial used amoxicillin and DMSO as negative control. The results showed that ethanol extracts and fraction of akar kuning (Fibraurea tinctoria Lour.) are have potential to inhibited bacteria growth. The highest antibacterial activity that showed at 10% concentration of ethanol extract with diameter inhibition is 9,18 mm to Escherichia coli and 12,16 mm to Staphylococcus aureus while the fraction of akar kuning which has the stronger antibacterial activity to Escherichia coli and Staphylococcus aureus is the rest fraction. Staphylococcus aureus were more susceptible to akar kuning (Fibraurea tinctoria Lour.) extract and fraction than Escherichia coli.Keywords:           antibacterial, akar kuning, berberin, Fibraurea tinctoria Lour
PELATIHAN PEMBUATAN HAND SANITIZER BAGI MASYARAKAT KELURAHAN TELUK LERONG ULU DAN BUGIS, SAMARINDA Reksi Sundu; Henny Nurhasnawati; Eka Siswanto Syamsul; Rio Adi Saputra
Jurnal Abdi Masyarakat Kita Vol 1 No 2 (2021): Jurnal Abdi Masyarakat Kita
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1289.018 KB) | DOI: 10.33759/asta.v1i2.162

Abstract

Health is an important aspect of life. According to the World HealthOrganization (WHO), hand hygiene is one of the most important steps to prevent and control the spread of disease (maintaining health). At the time of activity, hands are often contaminated with microorganisms because the hands are an intermediary for the entry of microbes into the digestive tract. The purpose of this activity is to provide education to the community, especially those in TelukLerong Ulu and Bugis Villages about how to make hand sanitizer. The method of this activity is lecture, discussion and training. Community service activities in TelukLerong Ulu and Bugis Villages on June 24, 2020 went smoothly and received a good response. Each participant brought home their own homemade product.
ANALISIS FRAGMENTASI GC-MS SENYAWA AKTIF ANTIKANKER LEUKEMIA FRAKSI KLOROFORM UMBI BAWANG TIWAI (Eleutherine bulbosa (Mill.) Urb) Dwi Lestari; Rudi Kartika; Eva Marlina; Eka Siswanto Syamsul
Jurnal Ilmiah Manuntung Vol 5 No 1 (2019): Jurnal Ilmiah Manuntung
Publisher : jurnal ilmiah manuntung sekolah tinggi ilmu kesehatan samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v5i1.181

Abstract

Tiwai Onion (Eleutherine bulbosa (Mill.) Urb.) is an Iridaceae tribe which is a typical plant of Borneo. Its used by the Dayak community, among others, for colon cancer, breast cancer, diabetes mellitus, hypertension, lowering cholesterol, strokes, boils, anti-bleeding and abdominal pain. The purpose of this study was to determine the components of anticancer compounds of chloroform fraction by GC-MS method. The results of GC-MS spectrum analysis based on the base peak equation of the chloroform fraction contain 9,12-Octadecadienoic Acid, and 1- (2,3,5,6-Tetramethyl phenyl) Ethanone which has the potential as an anticancer.
UJI AKTIVITAS ANTIBAKTERI EKSTRAK ETANOL DAN FRAKSI Archidendron clypearia TERHADAP Staphylococcus aureus dan Salmonella typhi : ANTIBACTERIAL ACTIVITY TEST OF ETANOL EXTRACT AND FRACTIONS OF Archidendron clypearia OF Staphylococcus aureus and Salmonella typhi Octaviani, Bella Micha Thesya; Fahmi, Supomo; Syamsul, Eka Siswanto
JFL : Jurnal Farmasi Lampung Vol. 14 No. 1 (2025): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v14i1.2532

Abstract

Infection is one of the most common causes of disease in society. One type of infection caused by Staphylococcus aureus is a bacterium that causes skin infections in humans characterized by purulent abscesses. In addition, Salmonella typhi is also a pathogenic bacterium that can cause typhoid fever. Infections caused by microorganisms can be overcome by administering antimicrobials. One of the natural ingredients that has the potential as an antimicrobial is the petai belalang plant (Archidendron clypearia). This study aims to test the antibacterial activity of ethanol extracts and fractions of petai belalang leaves against Staphylococcus aureus and Salmonella typhi bacteria. This experimental research includes plants determination, sampling, making simplisia, fractionation, phytochemical screening, and antibacterial activity tests. Extracts and fractions were prepared in concentrations of 1%, 5%, 10%, and 15%, with positive control of amoxicillin 0.1% and negative control of DMSO 1%. The antibacterial activity test was performed using disc diffusion and pitting diffusion methods to measure the zone of inhibition. Data were statistically analyzed using the Kruskal-Wallis test. The results showed that in the disc diffusion method, the inhibition zone against Staphylococcus aureus was 7.3-10.8 mm, and against Salmonella typhi was 7.6-10.1 mm. In the well diffusion method, the zone of inhibition against Staphylococcus aureus ranged from 12.1-16.8 mm, and against Salmonella typhi it ranged from 12.5-16.8 mm. The ethyl acetate fraction obtained the largest inhibition zone with a diameter of 16.8 mm in the well diffusion method. Statistical analysis showed a significant difference in antibacterial activity on positive and negative bacteria with a substantial value of 0.005 in the disc method and 0.006 in the well method. Keywords: Antibacterial, petai belalang, Staphylococcus aureus, Salmonella typhi
Uji Aktivitas Antibakteri EkstrakEtanol dan Fraksi Batang Kuning (Fibraurea Tinctoria Lour) terhadap Bakteri Escherichia coli dan Staphylococcus aureus Ariyanti, Lusi Mardika; Supomo, Supomo; Sa’adah, Hayatus; Syamsul, Eka Siswanto; Kintoko, Kintoko; Witasari, Hardi Astuti
JI-KES (Jurnal Ilmu Kesehatan) Vol. 5 No. 2 (2022): JI-KES (Jurnal Ilmu Kesehatan)
Publisher : LPPM Universitas Hafshawaty Zainul Hasan Probolinggo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33006/ji-kes.v5i2.323

Abstract

Abstrak Akar kuning (Fibraurea tinctoria Lour) merupakan tumbuhan khas yang dapat dijumpai di Kalimantan serta biasa dimanfaatkan oleh masyarakat setempat sebagai obat gatal, penyakit kuning dan diare. Salah satu senyawa kimia yang terkandung dalam akar kuning adalah berberin yang berpotensi memiliki khasiat sebagai antidiabetes, antivirus, antibakteri dan antiinflamasi. Penelitian ini bertujuan untuk  mengetahui potensi tumbuhan Akar Kuning (Fibraurea tinctoria Lour.) sebagai antibakteri terhadap bakteri Escherichia coli dan Staphylococcus aureus dengan menggunakan metode disc diffusion. Ekstrak etanol difraksinasi dengan menggunakan pelarut n-heksan dan etilasetat, ekstrak dan fraksi yang telah didapat ditimbang dengan konsentrasi 2,5%, 5% dan 10%. Kontrol positif yang digunakan yaitu amoxicillin dan DMSO sebagai kontrol negatif. Hasil penelitian menunjukkan bahwa ektrak etanol dan fraksi akar kuning (Fibraurea tinctoria Lour.) memiliki potensi untuk menghambat pertumbuhan bakteri. Aktivitas zona hambat terbesar yang terbentuk pada ekstrak etanol yaitu pada konsentrasi 10% dengan diameter zona hambat 9,18 mm terhadap bakteri Escherichia coli dan 12,16 mm terhadap bakteri Staphylococcus aureus sedangkan fraksi batang akar kuning yang memiliki aktivitas antibakteri paling kuat terhadap bakteri Escherichia coli dan Staphylococcus aureus yaitu fraksi sisa. Staphylococcus aureus memiliki sensitifitas lebih tinggi terhadap akar kuning (Fibraurea tinctoria Lour) dari pada bakteri Escherichia coli. Kata kunci  : antibakteri, akar kuning, berberin, Fibraurea tinctoria Lour. Abstract Akar kuning (Fibraurea tinctoria Lour.) is typically plant that can be found in Kalimantan usually used by local people as itch medicine, jaundice and diarrhea. Berberin, one of the chemical compounds contained in the akar kuning, berberin has the potential to act as an anti-diabetic, antiviral, antibacterial, and anti-inflammatory. This study aimed to determine the activity of akar kuning as an antibacterial against Escherichia coli and Staphylococcus aureus using the disc diffusion method. Ethanol extract are fractionated using n-Heksan and Etilasetat solvents, the obtained of extract and fraction are weighed to 2,5%, 5% and 10%. Positive control antibacterial used amoxicillin and DMSO as negative control. The results showed that ethanol extracts and fraction of akar kuning (Fibraurea tinctoria Lour.) are have potential to inhibited bacteria growth. The highest antibacterial activity that showed at 10% concentration of ethanol extract with diameter inhibition is 9,18 mm to Escherichia coli and 12,16 mm to Staphylococcus aureus while the fraction of akar kuning which has the stronger antibacterial activity to Escherichia coli and Staphylococcus aureus is the rest fraction. Staphylococcus aureus were more susceptible to akar kuning (Fibraurea tinctoria Lour.) extract and fraction than Escherichia coli.Keywords:           antibacterial, akar kuning, berberin, Fibraurea tinctoria Lour