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Systematic Review: Impact of Air Pollution on DNA Methylation Akbar, Muhammad Ihzario Ibrahim; Tualeka, Abdul Rohim; Zurimi, Suardi; Jalaludin, Juliana
Media Gizi Kesmas Vol 14 No 1 (2025): MEDIA GIZI KESMAS (JUNE 2025)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v14i1.2025.165-175

Abstract

Background: Quality of life is an important. It is influenced by exposure to chemicals in the body, such as air pollution, which can damage supporting life in the future. Objective: The aim of writing this systematic review is to specify the impact of air pollution on DNA methylation. Methods: The method in this study uses the Preferred Reporting Items for Systematic Review and Meta-analyses, this methode is carried out by searching for data in the form of articles or journals, which is carried out using the keywords "Air pollution" and "DNA methylation". Overall data from articles or jurnals based on searches using the keywords "Air pollution" and "DNA Methylation" (n=25), data from articles or journals focused on this research and articles or journals that can be accessed for free with the year publication year in the last 10 years (n=20), after which they are adjusted to the inclusion criteria of this study (n=15). Result: In this study, the results of the systematic review were obtained that this long-term impact will affect a person's quality of life, apart from that, it can also cause serious complications such as repeated respiratory infections, which can lead to decreased lung function and a higher risk of death. Conclusion: DNA is a logical tool for understanding the impact of air pollution on genome function and downstream activities that benefit health.
Heavy Metals Pollution in Drinking Water Sources: A Case Study from Kulim Hi-Tech Park, Malaysia Zainon, Muhamad Radzi; Aziz, Mohd Yusmaidie; Ishak, Ahmad Razali; Abdullah, Muhamad Azwat; Tualeka, Abdul Rohim; Mohamed, Rafeezul; Edinur, Hisham Atan; Mualif, Siti Aisyah; Zabidi, Muhammad Azrul; Waras, Maisarah Nasution
JURNAL KESEHATAN LINGKUNGAN Vol. 17 No. 3 (2025): JURNAL KESEHATAN LINGKUNGAN
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jkl.v17i3.2025.256-267

Abstract

Introduction: Heavy metal content within drinking water poses significant risks to health and the environment. Given industrial impact on Kulim’s water quality, this study determined the concentrations of iron (Fe), manganese (Mn), zinc (Zn), cadmium (Cd), and nickel (Ni) in various water sources around Kulim Hi-Tech Park (KHTP) and assess associated with chronic heath risks. Methods: We measured these five heavy metals in 30 water samples from tap water, rivers, and ponds, within and around Kulim Hi-Tech Park (KHTP), using Atomic Absorption Spectroscopy. Non-carcinogenic risk was assessed by calculating Hazard Quotient (HQ) and Hazard Index (HI), while carcinogenic risk used Excess Lifetime Cancer Risk (ELCR). Results and Discussion: Mean concentrations averaged between 0.0177 ± 0.0017 mg/L and 0.8652 ± 0.0606 mg/L; nickel showed the highest mean, followed by iron, zinc, manganese, and cadmium. Notably, concentrations of nickel, and in some instances iron and cadmium, exceeded regulatory limits. HQ and HI suggested no immediate adverse health effects from exposure to iron, manganese, and zinc. However, ELCR values for cadmium and nickel surpassed acceptable levels, indicating potential carcinogenic risks from long-term exposure. It is important to note that risk assessment for iron, manganese, and zinc is based on mean concentrations that include proportion of samples below the Limit of Quantification (LOQ), warranting cautious interpretation. Conclusion: This study provides crucial baseline data on heavy metals in KHTP water resources, underscores more investigation and potential remediation strategies to safeguard public and environmental health.
Analisis Kebisingan dengan Menggunakan Peta Kebisingan serta Rekomendasi Program NIHL (Noise Induced Hearing Loss) di PT. Wijaya Karya Beton, Tbk. PPB Pasuruan Shalina, Nia Vita; Tualeka, Abdul Rohim
Journal of Applied Civil Engineering and Infrastructure Technology Vol 6 No 2 (2025): Desember 2025
Publisher : Indonesian Society of Applied Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52158/jaceit.v6i2.989

Abstract

Noise is one of the environmental issues that frequently occurs in the workplace, particularly in the manufacturing industry. Excessive and prolonged exposure to noise can cause health problems for workers, such as Noise-Induced Hearing Loss (NIHL). PT. Wijaya Karya Beton, Tbk. PPB Pasuruan, in its production process, uses various machines and equipment that can produce quite high noise levels. To overcome the noise problem at PT. Wijaya Karya Beton, Tbk. PPB Pasuruan, it is necessary to create a noise description using a noise map, so that monitoring can be carried out. In addition, implementing the NIHL (Noise-Induced Hearing Loss) program is needed to prevent and reduce the risk of hearing loss in workers. This study aims to describe noise using a noise map and provide recommendations for noise control efforts in the form of Noise-Induced Hearing Loss (NIHL). The method used is descriptive observational, with primary data from direct observation and secondary data from noise measurements conducted by PT. Envilab Indonesia. The results of the study showed that noise levels in several production areas exceeded the permitted threshold, with the highest noise intensity reaching 89.7 dBA. Recommendations include the use of ear protection, regular noise monitoring, and worker education on noise hazards. Implementation of the NIHL program is expected to reduce the risk of hearing loss and improve occupational health and safety.
Hubungan Antara Karakteristik Individu Dengan Degenerasi DNA Pada Pekerja Bengkel Pengecatan Mobil Surabaya Ulubiah, Siti Marifatul; Tualeka, Abdul Rohim; Ahsan, Ahsan; Jalaludin, juliana
Media Gizi Kesmas Vol 11 No 1 (2022): MEDIA GIZI KESMAS (JUNE 2022)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v11i1.2022.283-290

Abstract

Latar Belakang: Kandungan pada komposisi cat maupun thinner terdapat BTX. Kandungan yang digunakan tersebut bersifat toksik dan bahkan karsinogenik. Dengan demikian, paparan BTX yang tidak terkontrol akan menyebabkan gangguan kesehatan pada pekerja. Beberapa metabolit BTX yang menghasilkan produksi ROS dan dapat menyebabkan terjadinya stress oksidatif serta kerusakan genetic. Interaksi yang terjadi antara ROS dengan biomolekul salah satunya DNA dapat menyebabkan terjadinya kerusakan DNA oksidatif. Tingkat keparahan kerusakan DNA juga dapat dipengaruhi oleh karakteristik individu antara lain usia, masa kerja, dan status merokok. Tujuan: untuk menganalisis hubungan antara karakteristik individu dengan degenerasi DNA pada pekerja bengkel pengecatan mobil di Surabaya. Metode: Penelitian ini merupakan penelitian observasional deskriptif dengan analisis kuantitatif dan rancang bangun cross sectional. Sampel penelitian sebanyak 20 orang dengan metode sampling yaitu total population sampling. Penelitian dilakukan di bengkel pengecatan mobil Kalijudan, Surabaya. Variabel penelitian terdiri atas variable independen (karakteristik indvidu meliputi usia, masa kerja, dan status merokok) dan variable dependen (degenerasi DNA). Analisis variable menggunakan tabel distribusi frekuensi, uji coefficient contingency, dan uji korelasi point-biserial. Hasil: Hubungan antara karakteristik individu dengan degenerasi DNA yaitu usia (kategori sedang dan berarah negative), masa kerja (kategori sangat lemah dan berarah negative), dan status merokok (kategori sangat lemah dan berarah positif). Kesimpulan: Hubungan antara karakteristik individu dengan degenerasi DNA pada pekerja bengkel pengecatan mobil di Surabaya berada pada kategori sedang dan sangat lemah dengan arah positif maupun negative. Meski hubungan yang terjadi tidak bersifat kuat, namun pihak industry atau pemilik bengkel pengecatan mobil sebaiknya menyediakan dan menganjurkan pemakaian Alat Pelindung Diri (APD) sebagai bentuk pencegahan terhadap pekerja.
Hubungan Konsentrasi Benzena Dengan Kadar Eritosit Pada Pekerja Produksi AUP Surabaya Karisma Putri, Frizki Rana; Tualeka, Abdul Rohim; Jalaludin, juliana; Ahsan, Ahsan
Media Gizi Kesmas Vol 11 No 1 (2022): MEDIA GIZI KESMAS (JUNE 2022)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v11i1.2022.225-230

Abstract

Latar Belakang: Industri percetakan adalah industri tulisan dan gambar massal yang menggunakan tinta pada kertas dan mesin cetak. Dalam proses produksinya digunakan tinta dan pelarut yang mengandung bahan kimia, salah satunya adalah benzena. Paparan benzena dapat meningkatkan konsentrasi benzena di lingkungan kerja serta meningkatkan risiko kesehatan bagi pekerja. Benzene menargetkan darah yang dapat mengurangi jumlahsel darah yang ada dalam tubuh atau anemiaTujuan: Untuk mengetahui hubungan antara konsentrasi benzena dengan eritrosit dan hemoglobin pada pekerja bagian produksi di Airlangga University Press. Metode: Variabel bebas yang digunakan adalah konsentrasi benzena dan variabel terikatnya adalah kadar eritrosit dan hemoglobin. Penelitian ini menggunakan metode observasional dengan pendekatan kuantitatif dan cross sectional. Semua 11 pekerja produksi di perusahaan percetakan Airlangga University Press diambil sebagai sampel dalam penelitian ini. Data dianalisis menggunakan uji normalitas Shapiro-Wilk dan uji korelasi PearsonHasil: konsentrasi benzena pada pekerja produksi percetakan berada di bawah nilai ambang batas. Rerata kadar hemoglobin dan eritrosit pekerja dalam batas normal. Tidak ada hubungan yang signifikan antara konsentrasi benzena dengan eritrosit (p = 0,816) pada pekerja di bagian produksi percetakan Airlangga University PressKesimpulan: Efek kesehatan yang terjadi akibat paparan benzena adalah gangguan sistem hematologi dimana target utama benzena adalah sumsum tulang. Paparan benzena dapat menurunkan jumlah sel darah dan berkontribusi pada jumlah leukosit, eritrosit, dan trombosit di perifer dara
Hubungan Karakteristik Individu, Konsentrasi Benzena dengan Degenerasi DNA Pada Pekerja Pengecatan Mobil Asih, Heningdia Pastika; Abdul Rohim Tualeka
Media Gizi Kesmas Vol 11 No 2 (2022): MEDIA GIZI KESMAS (DECEMBER 2022)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v11i2.2022.416-425

Abstract

Background: A car paint shop is one of the works that use paint as the main working material containing benzene. Benzene is a colorless liquid aromatic compound that is carcinogenic to humans. This compound is classified as a group 1 human carcinogen by the IARC (International Agency for Research on Cancer). Objectives: This study aimed to analyze the correlation between individual characteristics and workplace benzene concentrations with DNA degeneration of workers in an automotive paint shop in Kalijudan, Surabaya. Methods: This study is an observational study with a cross-sectional design and a quantitative approach. Secondary data from the previous study were collected from 20 respondents, all of whom were paint workers in an auto paint shop. The dependent variable in this study is DNA degeneration and the independent variables are age, body mass index (BMI), number of years working, smoking behavior, and benzene concentration. To analyze the correlation of independent and dependent variables, the chi-square test was used. And then the phi test and Cramer's v are used to analyze the strength of the correlation between the two variables. Results: Measurements of benzene concentrations in the workplace showed higher mean concentrations than TLV-TWA. As a result of laboratory tests, 13 out of 20 workers showed DNA degeneration. At the same time, the results showed a moderate correlation between BMI and DNA degeneration, and a very weak correlation between benzene concentration at work, individual characteristics (worker age, years of work, and smoking behavior) and DNA degeneration. Conclusions: This study found no correlation between individual characteristics and workplace benzene concentration with DNA degeneration in Surabaya auto paint shop workers. Keywords: benzene, car painting shop, DNA, individual characteristics
Hubungan antara Kepatuhan Penggunaan APD (Alat Pelindung Diri) dengan Dampak Paparan sianida di Area HLO (Heap Leach Operation) PT. Bumi Suksesindo Anwar, Diana; Tualeka, Abdul Rohim; Lailiyah, Syifa'ul
Media Gizi Kesmas Vol 13 No 1 (2024): MEDIA GIZI KESMAS (JUNE 2024)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v13i1.2024.110-115

Abstract

Background: The mining sector plays a crucial role as a significant contributor to the energy supply, which is vital for economic growth. However, mining activities pose various potential hazards. Unfortunately, compliance with the usage of Personal Protective Equipment (PPE) in this industry remains relatively low. Objectives: The objective of this research is to analyze the relationship between workers' compliance in using PPE and the potential impact of cyanide exposure in the Heap Leach Operation (HLO) irrigation area of PT. Bumi Suksesindo. Methods: This study employed a quantitative research approach using an observational analytical method and a cross-sectional design. The research population consisted of 33 workers in the irrigation section of the HLO area. Data collection is conducted through questionnaire surveys, and the obtained data are analyzed using the contingency coefficient (c) to determine the strength of the relationship between variables. Results: The majority of workers (60.6%) were not exposed to the impact of cyanide exposure. There is a very weak correlation between compliance in using PPE and the potential impact of cyanide exposure (c = 0.141) Conclusions: A very weak correlation exists between workers' compliance in using PPE and the potential impact of cyanide exposure in the HLO irrigation area of PT Bumi Suksesindo.
Hubungan Beban Kerja Mental dan Kelelahan Kerja dengan Stres Kerja pada Perawat Shift Malam Rumah Sakit Islam Fatimah Banyuwangi Aminulloh, Sandi; Tualeka, Abdul Rohim
Media Gizi Kesmas Vol 13 No 1 (2024): MEDIA GIZI KESMAS (JUNE 2024)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v13i1.2024.370-376

Abstract

Background: Every company is obliged to implement Occupational Safety and Health (K3) in the workplace. Implementation of this concept is the most important step to ensure work safety, protect workers and promote a higher level of health, so that workers can avoid various risks that endanger workers. One of the dangers at work is the psychological aspect, namely work stress. The American National Institutes of Health states that nursing is a job at risk of experiencing work stress at number 27 out of 130 types of work. The high workload on nurses can fluctuate the work stress experienced by them. Objective: This study aims to find the relevance or relationship between gender, length of service, mental workload, age, and work fatigue with work stress in nurses in the night shift work system at the emergency installation at the Banyuwangi Islamic Fatimah Hospital. Method: This research is quantitative with statistical analysis of the Spearman correlation coefficient. Results: The results of the study showed that there was no relationship between age, gender, years of work, mental workload and work stress. In addition, a relationship was found between work fatigue and work stress. Conclusion: Overall, it can be concluded that age, gender, length of service and workload for nurses are not related to work stress. However, the work fatigue of nurses at Fatimah Banyuwangi Islamic Hospital is related to the nurses' work stress.
Analisis Hubungan Beban Kerja Fisik Dengan Kelelahan Kerja Penambang Belerang PT. X Banyuwangi Taurizanti, Nadia Firdausi; Tualeka, Abdul Rohim
Media Gizi Kesmas Vol 13 No 1 (2024): MEDIA GIZI KESMAS (JUNE 2024)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v13i1.2024.413-418

Abstract

Background: Indonesia is a country with abundant natural resources, one of which is the potential for sulfur in Banyuwangi Regency. This natural potential is managed by PT. X Banyuwangi with the number of workers reaching 249 sulfur miners in the area. Excessive physical workload was found in the mining operational process in the Mount Ijen crater, resulting in a high potential for work fatigue which could lead to work accidents in this business sector. Objective: This study aims to examine the relationship between age, length of service and physical workload with work fatigue of sulfur miners of PT. X Banyuwangi. Method: The research method used is quantitative observational with data analysis using Spearman correlation and correlation coefficient values. Results: The results of the study showed that there was a relationship between age and physical workload and work fatigue of sulfur miners of PT. X Banyuwangi. Apart from that, there is no relationship between work period and work fatigue of sulfur miners of PT. X Banyuwangi. Conclusion: Overall, it can be concluded that age and physical workload are related to work fatigue, while work experience is not related to work fatigue. The recommendations that can be implemented are implementing standard operational procedures in the process of transporting sulfur mining products which is carried out over a distance of 3 km, providing a shift system that allows miners to have working hours in accordance with Indonesian regulations, and providing physical workload limits in the manual handling process. which was carried out in the process of transporting sulfur mining products in the crater area of "‹"‹Mount Ijen, Banyuwangi.
ELECTRICAL INDUSTRY SAFETY: EXAMINING CONTROL STRATEGIES TO REDUCE ELECTRICAL RISKS BASED ON OSHA AND BLS (2011-2021) REPORTS Azeez Olawale Ojelabi; Abdul Rohim Tualeka; Indriati Paskarini; Suardi Zurimi; Juliana Jalaludin
Journal of Vocational Health Studies Vol. 9 No. 2 (2025): November 2025 | JOURNAL OF VOCATIONAL HEALTH STUDIES
Publisher : Faculty of Vocational Studies, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jvhs.V9.I2.2025.146-153

Abstract

Background: One essential component of contemporary society is the use of electricity in a variety of industrial sectors. However, its vital role brings inherent risks that demand strict adherence to safety precautions. Purpose: This literature review investigates and evaluates control measures implemented in the electrical industry to reduce risks and lower the incidence of electrical fatalities. The analysis focuses on the effectiveness of these control strategies and their alignment with the hierarchy of control framework. Review: This literature review employs a descriptive quantitative analysis. This study analyzes data from 2011 to 2021. During this period, the Bureau of Labor Statistics (BLS) reported 1.653 work-related electrical fatalities, while the Occupational Safety and Health Administration (OSHA) reported 1.201. Result: 118 vocations were linked to electrical fatalities during this time. Of these, 31% of deaths occurred in electrical-related jobs, while 69% happened in non-electrical jobs. This finding highlights the urgent need for comprehensive safety measures and effective control strategies to mitigate electrical hazards. Conclusion: This literature review highlights the importance of applying the Hierarchy of Controls (HOC) in managing electrical risks in the workplace. It calls for proactive interventions and a cultural shift toward prioritizing safety, integrating human awareness with strict regulations to reduce electricity-related fatalities.
Co-Authors Abdullah, Muhamad Azwat Ahmad Rido'i Yuda Prayogi Ahmad Rido'i Yuda Prayogi Ahmad Ridoi Yuda Prayogi Ahsan Ahsan Ahsan Ahsan Ahsan Ahsan Ahsan Ahsan Ahsan Aisyah Noor Shofi Hanifah Akbar, Muhammad Ihzario Ibrahim Alifia, Nabila Azzahra Amanda Fithri Habibati Aminulloh, Sandi Anwar, Diana Aristy Yulanda Ambarani Arya Zulfikar Paramarta Asih, Heningdia Pastika Astriningrum Titipangesti Kusumarini Aulia Rahman Farizky Pujiantara Azeez Olawale Ojelabi Aziz, Mohd Yusmaidie Bahsin, Alkaf Munis Bahsin, Alkaf Mu’nis Barikly Robby Basa Alim Tualeka Bella Puspitaloka, Nanda Dani Nasirul Haqi Dita Perwitasari Dr. Ahsan Ahsan Dr. Syamsiar S Russeng Edinur, Hisham Atan Enjelita Karujan Ernawati, Meirina Erwin Dyah Nawawiwetu, Erwin Dyah Fadila, Isna Fahimah Hashim Firda Qurba Sari Fitri Yatulaini Frinsus Feriga Diosma Hafidzoh Fatihatul jannah Hanif Rizqi Diniari, Hanif Rizqi Harahap, Nurhani Mazly Iin Zulaiha Tuasikal Indri H Susilowati Indri H Susilowati Indri H Susilowati Indriati Paskarini Innaha Ilma Wardaya Intan Kristianti Irlangga Wisnu Wardana Irsyad Yudisianto Ishak, Ahmad Razali Ismahani Isman, Nur Izzah Istifara, Anindia Ivana Laily Jalaludin, Juliana Jatmiko, Hapsoro Agung Jayawarsa, A.A. Ketut Juliana Jalaludin Juliana Jalaludin Juliana Jalaludin Kania Nayuri Nugroho Karisma Putri, Frizki Rana Kusumarini, Astriningrum Titipangesti Lailiyah, Syifa'ul M. Subandi, Baharuddin Mahfiro Risky Safitri Mahima, A.A.Gede Kenas Alvaro Mandagi, Ayik Mirayanti Mardliyatus Sholihah Mardliyatus Sholihah, Mardliyatus Melany Kumayas Mohamed, Rafeezul Mualif, Siti Aisyah Nita Desti Rahmawati Noeroel Widajati Nugraha, Rizki Ahmad Ojelabi, Azeez Olawale Prasetya, Tofan Agung Eka Pudji Rahmawati Putri, Wulandari Anggraini Rahmadani Rahmadani Rizaldi Nanda Pratama Rizaldy Fathur Rachman Rizaldy Fathur Rachman Sacharina Surya Ningrum Safitrie, Olga Febriana Salsabila Novianti Salsabila Novianti Samsul Arifin Sarah Nadhila Rahma Setyawati, Evi Shalina, Nia Vita Shintia Yunita Arini, Shintia Yunita Shoshihandra, Doutti Sillehu, Sahrir Siti Arum Alia Siwidati, Anggit Wirama Suardi Zurimi Suardi Zurimi Suhaimi, Nur Faseeha Suherdin Suherdin Suwardi Suwardi Syamsiar Russeng Syamsiar S Russeng Syamsiar S Russeng Syamsiar S Russeng Tamilanban Thamaraikani Taurizanti, Nadia Firdausi Tri Martiana Tri Martiana Trias Mahmudiono Ulfa, Ni'matul Ulubiah, Siti Marifatul Velu Perumal Wahdah Dhiyaul Akrimah Waras, Maisarah Nasution Widjajati, Noeroel Y Denny Ardyanto W Yenitrisnawati Zabidi, Muhammad Azrul Zainon, Muhamad Radzi Zulfa Anida Zurimi, Suardi