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Hubungan Antara Karakteristik Individu Dengan Degenerasi DNA Pada Pekerja Bengkel Pengecatan Mobil Surabaya Siti Marifatul Ulubiah; Abdul Rohim Tualeka; Ahsan Ahsan; juliana Jalaludin
Media Gizi Kesmas Vol 11 No 1 (2022): MEDIA GIZI KESMAS (JUNE 2022)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v11i1.2022.283-290

Abstract

Latar Belakang: Kandungan pada komposisi cat maupun thinner terdapat BTX. Kandungan yang digunakan tersebut bersifat toksik dan bahkan karsinogenik. Dengan demikian, paparan BTX yang tidak terkontrol akan menyebabkan gangguan kesehatan pada pekerja. Beberapa metabolit BTX yang menghasilkan produksi ROS dan dapat menyebabkan terjadinya stress oksidatif serta kerusakan genetic. Interaksi yang terjadi antara ROS dengan biomolekul salah satunya DNA dapat menyebabkan terjadinya kerusakan DNA oksidatif. Tingkat keparahan kerusakan DNA juga dapat dipengaruhi oleh karakteristik individu antara lain usia, masa kerja, dan status merokok. Tujuan: untuk menganalisis hubungan antara karakteristik individu dengan degenerasi DNA pada pekerja bengkel pengecatan mobil di Surabaya. Metode: Penelitian ini merupakan penelitian observasional deskriptif dengan analisis kuantitatif dan rancang bangun cross sectional. Sampel penelitian sebanyak 20 orang dengan metode sampling yaitu total population sampling. Penelitian dilakukan di bengkel pengecatan mobil Kalijudan, Surabaya. Variabel penelitian terdiri atas variable independen (karakteristik indvidu meliputi usia, masa kerja, dan status merokok) dan variable dependen (degenerasi DNA). Analisis variable menggunakan tabel distribusi frekuensi, uji coefficient contingency, dan uji korelasi point-biserial. Hasil: Hubungan antara karakteristik individu dengan degenerasi DNA yaitu usia (kategori sedang dan berarah negative), masa kerja (kategori sangat lemah dan berarah negative), dan status merokok (kategori sangat lemah dan berarah positif). Kesimpulan: Hubungan antara karakteristik individu dengan degenerasi DNA pada pekerja bengkel pengecatan mobil di Surabaya berada pada kategori sedang dan sangat lemah dengan arah positif maupun negative. Meski hubungan yang terjadi tidak bersifat kuat, namun pihak industry atau pemilik bengkel pengecatan mobil sebaiknya menyediakan dan menganjurkan pemakaian Alat Pelindung Diri (APD) sebagai bentuk pencegahan terhadap pekerja.
Hubungan Konsentrasi Benzena Dengan Kadar Eritosit Pada Pekerja Produksi AUP Surabaya Frizki Rana Karisma Putri; Abdul Rohim Tualeka; juliana Jalaludin; Ahsan Ahsan
Media Gizi Kesmas Vol 11 No 1 (2022): MEDIA GIZI KESMAS (JUNE 2022)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v11i1.2022.225-230

Abstract

Latar Belakang: Industri percetakan adalah industri tulisan dan gambar massal yang menggunakan tinta pada kertas dan mesin cetak. Dalam proses produksinya digunakan tinta dan pelarut yang mengandung bahan kimia, salah satunya adalah benzena. Paparan benzena dapat meningkatkan konsentrasi benzena di lingkungan kerja serta meningkatkan risiko kesehatan bagi pekerja. Benzene menargetkan darah yang dapat mengurangi jumlahsel darah yang ada dalam tubuh atau anemiaTujuan: Untuk mengetahui hubungan antara konsentrasi benzena dengan eritrosit dan hemoglobin pada pekerja bagian produksi di Airlangga University Press. Metode: Variabel bebas yang digunakan adalah konsentrasi benzena dan variabel terikatnya adalah kadar eritrosit dan hemoglobin. Penelitian ini menggunakan metode observasional dengan pendekatan kuantitatif dan cross sectional. Semua 11 pekerja produksi di perusahaan percetakan Airlangga University Press diambil sebagai sampel dalam penelitian ini. Data dianalisis menggunakan uji normalitas Shapiro-Wilk dan uji korelasi PearsonHasil: konsentrasi benzena pada pekerja produksi percetakan berada di bawah nilai ambang batas. Rerata kadar hemoglobin dan eritrosit pekerja dalam batas normal. Tidak ada hubungan yang signifikan antara konsentrasi benzena dengan eritrosit (p = 0,816) pada pekerja di bagian produksi percetakan Airlangga University PressKesimpulan: Efek kesehatan yang terjadi akibat paparan benzena adalah gangguan sistem hematologi dimana target utama benzena adalah sumsum tulang. Paparan benzena dapat menurunkan jumlah sel darah dan berkontribusi pada jumlah leukosit, eritrosit, dan trombosit di perifer dara
Hubungan Karakteristik Individu, Konsentrasi Benzena dengan Degenerasi DNA Pada Pekerja Pengecatan Mobil Heningdia Pastika Asih; Abdul Rohim Tualeka
Media Gizi Kesmas Vol 11 No 2 (2022): MEDIA GIZI KESMAS (DECEMBER 2022)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v11i2.2022.416-425

Abstract

Background: A car paint shop is one of the works that use paint as the main working material containing benzene. Benzene is a colorless liquid aromatic compound that is carcinogenic to humans. This compound is classified as a group 1 human carcinogen by the IARC (International Agency for Research on Cancer). Objectives: This study aimed to analyze the correlation between individual characteristics and workplace benzene concentrations with DNA degeneration of workers in an automotive paint shop in Kalijudan, Surabaya. Methods: This study is an observational study with a cross-sectional design and a quantitative approach. Secondary data from the previous study were collected from 20 respondents, all of whom were paint workers in an auto paint shop. The dependent variable in this study is DNA degeneration and the independent variables are age, body mass index (BMI), number of years working, smoking behavior, and benzene concentration. To analyze the correlation of independent and dependent variables, the chi-square test was used. And then the phi test and Cramer's v are used to analyze the strength of the correlation between the two variables. Results: Measurements of benzene concentrations in the workplace showed higher mean concentrations than TLV-TWA. As a result of laboratory tests, 13 out of 20 workers showed DNA degeneration. At the same time, the results showed a moderate correlation between BMI and DNA degeneration, and a very weak correlation between benzene concentration at work, individual characteristics (worker age, years of work, and smoking behavior) and DNA degeneration. Conclusions: This study found no correlation between individual characteristics and workplace benzene concentration with DNA degeneration in Surabaya auto paint shop workers. Keywords: benzene, car painting shop, DNA, individual characteristics
Analisis Hubungan Paparan Benzena dengan Faal Ginjal Pekerja Percetakan di Kota Surabaya Yenitrisnawati; Noeroel Widjajati; Abdul Rohim Tualeka; Evi Setyawati
Media Gizi Kesmas Vol 12 No 1 (2023): MEDIA GIZI KESMAS (JUNI 2023)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v12i1.2023.260-266

Abstract

Background: Benzene is a chemical whose exposure can cause occupational diseases arising from work activities, one of which can cause cancer. The sources of benzene in printing can come from ink cartridges, cylinders and in printers that are not closed. Objectives: This study aimed to analyze the relationship between benzene exposure and BUN and creatine levels of printing workers in Surabaya. Methods: This research is a descriptive observational study with a cross sectional design. The subjects of this study were 30 people who had met the criteria. The independent variables in this study were the levels of benzene in the air and the characteristics of workers, including age, years of service, and use of personal protective equipment (PPE). The dependent variable is BUN and creatinine as an indicator of kidney function. Results: The results showed that benzene concentration at six measurement points with the highest value was 15.64 ppm (already exceeding NAV). In the RQ calculation, there are 25 workers whose value is >1. The relationship between benzene concentrations with BUN and creatinine levels was in the unidirectional category and a strong correlation for BUN (r = 0.653) and sufficient for creatinine (r = 0.582), the relationship between age and BUN and creatinine levels was in the unidirectional relationship category and the correlation was very weak (r = 0.209 ; r = 0.140), the relationship between years of service with BUN and creatinine levels is in the unidirectional relationship category with sufficient correlation (r = 0.461; r = 0.322), while the relationship between PPE use with BUN and creatinine levels is in the unidirectional relationship category with correlation was moderate (r = 0.389) for BUN and very weak (r = 0.225) for creatinine. Conclusions: Based on the results, it can be concluded that there is a very strong relationship between the concentration of benzene and BUN and a strong relationship between the concentration of benzene and creatinine.
Analisis Risiko Ketulian Pekerja Pemotong Rumput yang Terpapar Kebisingan di PT. Pertamina (Persero) Marketing Operation Region V Terminal Bahan Bakar Minyak Tanjung Wangi Olga Febriana Safitrie; Abdul Rohim Tualeka
Media Gizi Kesmas Vol 12 No 2 (2023): MEDIA GIZI KESMAS (DECEMBER 2023)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v12i2.2023.719-725

Abstract

Introductions: Lawn mow worker was at risk of deafness due to noise because the lawn mow worker was carried on the back. Continuous noise exposured can increase the risk of hearing loss. Objectives: The purposed of this study was to analyze the risk of deafness in lawn mower worker who were exposed to noise at PT. Pertamina (Persero) Marketing Operation Region V Terminal Bahan Bakar Minyak Tanjungwangi. Methods: This research is a quantitative study using a cross-sectional approach, furthermore the research is conducted at one time. Sampling used a total sampling technique with a total sample of 10 people as the unexposed group and 10 people as the exposed group. Retrieval of research data obtained by measuring environmental noise, measuring the threshold value of workers and questionnaires. As well as observing the work environment by researchers. Furthermore, data analysis was carried out on the strong relationship between noise and worker age, years of service, and use of Personal Protective Equipment (APT) on hearing status using the Pearson statistical test. Results: The results showed that the average noise intensity received by grass cutter workers was 87.43 dB, and at office locations it was 61.9 dB. The average Hearing Threshold Value of the exposed group in the left ear was 17.5 dB and the right ear was 19,5 dB. As well as in the unexposed group, the left ear was 21 dB and the right ear was 20.75 dB. Conclussion: Noise, age, years of service, and use of ear protection devices have a relationship to the hearing status of workers. Based on statistical tests, it showed that the value of p> 0.005, and then noise had a weak relationship with age, years of service and use of ear protection devices. The advice given to PT. Pertamina (Persero) TBBM Tanjungwangi is to supervise the use of ear protection devices for workers so as to reduce the risk of workers' deafness due to exposure to lawn mowers
Efek Vinil Klorida terhadap Metilasi DNA: Tinjauan Sistematis Nabila Azzahra Alifia; Abdul Rohim Tualeka
Media Gizi Kesmas Vol 12 No 2 (2023): MEDIA GIZI KESMAS (DECEMBER 2023)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v12i2.2023.1095-1106

Abstract

Background: Vinyl chloride (VC) is a toxic chemical hazard which is characterized with colorless gas widely used in the plastics manufacturing industry. Vinyl chloride (VC) has various health threatening effects such as bothering deoxyribonucleic acid (DNA) methylation that can cause hepatocellular carcinoma (HCC) and cancer. Objectives: The purpose of writing systematic review is to determine the effect vinyl chloride (VC) to deoxyribonucleic acid (DNA) methylation. Methods: The research design is a systematic review article using PRISMA method (Preferred Reporting Items for Systematic Reviews and Meta-analyses) method. This question is structured by taking into account 4 stages, namely:  Population, Intervention, Comparison, and Outcome (PICO). By searching for articles/journals that match the keywords in PICO, namely "vinyl chloride (VC)” and "DNA methylation” online via Google Scholar and PubMed. Through this search, 74 articles/ journals were obtained. Then an assessment of the suitability of the inclusion criteria that has been determined in the title, abstract, and content is carried out full text so that 8 articles/ journals were obtained. Results: Based on the results systematic review, picture of cause and effect relationship vinyl chloride (VC) against deoxyribonucleic acid (DNA) methylation has been found in industrial workers who inhibit deoxyribonucleic acid (DNA) methylation which ultimately causes risk of cancer and hepatocellular carcinoma (HCC). Conclusions: There is a connection between exposure vinyl chloride (VC) and deoxyribonucleic acid (DNA) methylation that cause health hazardous effects in the form of hepatocellular carcinoma (HCC) and cancer. It's necessary to have efforts to prevent and control exposure vinyl chloride (VC), one  of which is the use of Personal Protective Equipment (PPE). Results of this systematic review are very important to be used by the government as a reference in efforts to preventing and controlling chemical exposure vinyl chloride (VC) in the work environment.
Risk Assesment Pengelolaan Limbah Padat Medis Rumah Sakit Umum Daerah Gambiran Kota Kediri Doutti Shoshihandra; Abdul Rohim Tualeka
Media Gizi Kesmas Vol 12 No 2 (2023): MEDIA GIZI KESMAS (DECEMBER 2023)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v12i2.2023.840-846

Abstract

Background: Hospital waste is waste generated from hospital activities and other supporting activities that could have an impact on public health and the surrounding environment.  Problems that occurs due to medical solid waste which oftenly unseparated resulting in the occurrence of occupational disease and work-related accidents. Objectives: The aim of this research is targeting the implementation of risk assessment of medical solid waste management at Gambiran Public Hospital, Kediri City. Methods: This study is a descriptive study with quantitative methods applying cross sectional design.  The study was held at Gambiran Public Hospital on July 4th - August 5th 2022. Results: This results showed that the dangers of the medical solid waste management process at Gambiran Public Hospital, Kediri City, originate from collecting activities, sorting medical solid waste towards waste transportation, including needle punctured, contact with infectious materials and chemicals, inappropriate work postures such bending, squatting, lifting excess weight, as well as performing repetitive work. Other sources of threat arise from environment or construction including uneven pathways and slippery floors Conclusions: Based on the result of the medical solid waste management risk assessment, Gambiran Public hospital, Kediri City has a high risk of low back pain, back pain, hand pain, as well as being infected with infectious disease as an outcome of needle punctured accident.
Systematic Review: Efek Nanoplastik terhadap Metilasi DNA pada Manusia Anggit Wirama Siwidati; Abdul Rohim Tualeka
Media Gizi Kesmas Vol 12 No 2 (2023): MEDIA GIZI KESMAS (DECEMBER 2023)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v12i2.2023.1107-1116

Abstract

Background: Along with the times, plastic pollution is increasing and this is a problem throughout the world, especially in developing countries due to its very large amount, persistent nature and widespread use. Objectives: The purpose of this systematic review is to determine the effect of nanoplastics on deoxyribonucleic acid (DNA) methylation in humans Methods: The method used is PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-analyses). Data search in the form of articles or journals is carried out using the keywords "nanoplastics" and "DNA methylation". The inclusion criteria used were human population, nanoplastic effect, type of nanoplastic, amount and time of exposure, and DNA methylation. The data source used comes from Google Scholar, with the publication year starting from 2017-2022, and the language used is English Discussion: total data based on searches using the keywords "nanoplastics" and "DNA Methylation" (n=94), focusing on the study and research articles and free full text with the year of publication being the last 5 years (n=29), then adjusting the inclusion criteria (n=13). Conclusions: According to the results of the systematic review, it was concluded that there is a relationship between nanoplastics and DNA methylation. However, these results have limitations so it is necessary to conduct research with subjects that focus on workers. In addition, this systematic review has not been able to explain the special effects on workers in the industrial field due to limited literature obtained.
Hubungan antara Beban Kerja dengan Kelelahan Kerja pada Pedagang Sayur di Pasar Kota Baru Bojonegoro Ni'matul Ulfa; Abdul Rohim Tualeka
Media Gizi Kesmas Vol 12 No 2 (2023): MEDIA GIZI KESMAS (DECEMBER 2023)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v12i2.2023.906-913

Abstract

Background: The Labor Law has regulated various aspects of the protection of workers, one of which is occupational health and safety (K3). There are several factors that can trigger work accidents, one of which is fatigue and the informal sector is one of the sectors that has a high risk of experiencing work fatigue. Work fatigue can occur due to several factors, such as an unergonomic sitting work position, namely the wrong and static working position for a long time, an unequal ratio of working time and rest time, taking workload based on will not individual ability and psychological factors. High workload triggers a decrease in endurance, work efficiency and effectiveness, as well as a reduction in work capacity. Objectives: The purpose of this research is to analyze the relationship between the workload of vegetable traders at Pasar Kota Baru Bojonegoro and complaints of fatigue. Methods: An observational analytic design and used a cross sectional approach to 68 respondents. Physical workload can be assessed through pulse, mental workload is assessed through the NASA-TLX Questionnaire, and work fatigue is assessed using the SSRT Questionnaire issued by IFRC which was then analyzed using by Spearman correlation non-parametric test. Results: The majority of respondents were women (94.1%), aged in the early elderly category, namely 46 to 55 years (36.8%), had an elementary school education/MI/equivalent (42.6%), and had worked as a vegetable seller > 5 years (95.6%), has a workload (mental) in the moderate category (67.6%), has a workload (physical) in the low category (100%) and experiences work fatigue in the moderate category (63.2%). The results of the relationship test using the Spearman test showed that there was no significant relationship between (physical) workload and work fatigue with a sig. α = 0.469 and there is a relationship between workload (mental) and work fatigue for vegetable traders at Pasar Kota Baru Bojonegoro with a sig. α 0.042 and there is a weak relationship between workload (mental) and work fatigue with sig. α = 0.247. Conclusions: There is no relationship between workload (physical) and fatigue and there is a relationship between workload (mental) and work fatigue. Strong relationship is included in the weak category. Even so, these two factors must still be considered so that occupational diseases (PAK) and work-related accidents (KAK)
Literature Review: Pengaruh Enzim ALDH2 dalam Detoksifikasi Alkohol terhadap Sirosis Hati Anindia Istifara; Abdul Rohim Tualeka; Sahrir Sillehu
Media Gizi Kesmas Vol 12 No 2 (2023): MEDIA GIZI KESMAS (DECEMBER 2023)
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/mgk.v12i2.2023.1125-1132

Abstract

Background: Ethyl alcohol or also known as ethanol is organic compound and one of the active substances that is often abused by human. Currently alcohol misuse yhat cause health problems become a global issue. Alcohol has toxic effect to the body. Some disease caused by alcohol consumption such as alcoholic liver disease. The liver as main organ in the binding of chemical substances (detoxification) will occur fatty liver, cirrhosis, or even liver function damage if alcohol level that accumulate in the liver is excessive. Objectives: The purpose of the study is to analyzed the effect of ALDH2 enzyme on alcohol detoxification process in alcoholics. Methods: This research study used literature review method on previous studies with similar topic. The articles were obtained from Google Scholar, Science Direct, and PubMed that published in 2013-2023 by applying inclusion and exclusion criteria so the article that fulfilled criteria could be analyzed. Results: The result of the literature review from 5 articles showed that the ALDH2 enzyme had a role in alcohol detoxification process. This enzyme was inhibitor for the rate of acetaldehyde metabolism which had cytotoxic and carcinogenics effect. Excessive amount of alcohol, especially with ALDH2 defficiency caused accumulation of acetaldehyde in human body that could increase the risk of liver cirrhosis Conclusions: ALDH2 levels in human body have an influence on the occurrence of liver cirrhosis in alcoholic.
Co-Authors Abdullah, Muhamad Azwat Ahmad Rido'i Yuda Prayogi Ahmad Rido'i Yuda Prayogi Ahmad Ridoi Yuda Prayogi Ahsan Ahsan Ahsan Ahsan Ahsan Ahsan Ahsan Ahsan Ahsan Aisyah Noor Shofi Hanifah Akbar, Muhammad Ihzario Ibrahim Alia, Siti Arum Alkaf Mu’nis Bahsin Amanda Fithri Habibati Anggit Wirama Siwidati Anindia Istifara Aristy Yulanda Ambarani Arya Zulfikar Paramarta Astriningrum Titipangesti Kusumarini Aulia Rahman Farizky Pujiantara Azeez Olawale Ojelabi Aziz, Mohd Yusmaidie Baharuddin M. Subandi Bahsin, Alkaf Munis Barikly Robby Basa Alim Tualeka Dani Nasirul Haqi Diana Anwar Dita Perwitasari Doutti Shoshihandra Dr. Ahsan Ahsan Dr. Syamsiar S Russeng Edinur, Hisham Atan Enjelita Karujan Ernawati, Meirina Erwin Dyah Nawawiwetu, Erwin Dyah Evi Setyawati Fadila, Isna Fahimah Hashim Firda Qurba Sari Fitri Yatulaini Frinsus Feriga Diosma Frizki Rana Karisma Putri Hafidzoh Fatihatul jannah Hanif Rizqi Diniari, Hanif Rizqi Hapsoro Agung Jatmiko Heningdia Pastika Asih Iin Zulaiha Tuasikal Indri H Susilowati Indri H Susilowati Indri H Susilowati Indriati Paskarini Innaha Ilma Wardaya Intan Kristianti Irlangga Wisnu Wardana Irsyad Yudisianto Ishak, Ahmad Razali Ismahani Isman, Nur Izzah Ivana Laily Jalaludin, Juliana Jayawarsa, A.A. Ketut juliana Jalaludin Juliana Jalaludin Juliana Jalaludin Juliana Jalaludin Kania Nayuri Nugroho Ketut Ima Ismara Kusumarini, Astriningrum Titipangesti Made Yenny Puspitarini Mahfiro Risky Safitri Mahima, A.A.Gede Kenas Alvaro Mandagi, Ayik Mirayanti Mardliyatus Sholihah Mardliyatus Sholihah, Mardliyatus Melany Kumayas Moh. Nurdin Zuhri Mohamed, Rafeezul Mualif, Siti Aisyah Nabila Azzahra Alifia Nadia Firdausi Taurizanti Nanda Bella Puspitaloka Ni'matul Ulfa Nita Desti Rahmawati Noeroel Widajati Noeroel Widjajati Nur Aini Nur Aini Fitri Nurhani Mazly Harahap Ojelabi, Azeez Olawale Olga Febriana Safitrie Prasetya, Tofan Agung Eka Pudji Rahmawati Putri Ayuni Putri, Wulandari Anggraini Rahmadani Rahmadani Ritwan Agus Prasetyo Rizaldi Nanda Pratama Rizaldy Fathur Rachman Rizaldy Fathur Rachman Rosmita Rahma Dania Sacharina Surya Ningrum Sahrir Sillehu Salsabila Novianti Salsabila Novianti Samsul Arifin Samsul Arifin Sandi Aminulloh Sarah Nadhila Rahma Sari, Firda Qurba Shalina, Nia Vita Shintia Yunita Arini, Shintia Yunita Siti Arum Alia Siti Marifatul Ulubiah Suardi Zurimi Suhaimi, Nur Faseeha Suherdin Suwardi Suwardi Syamsiar Russeng Syamsiar S Russeng Syamsiar S Russeng Syamsiar S Russeng Syifa'ul Lailiyah Tamilanban Thamaraikani Tasya Ramadhani Tri Martiana Tri Martiana Tri Martiana Trias Mahmudiono Velu Perumal Wahdah Dhiyaul Akrimah Waras, Maisarah Nasution Y Denny Ardyanto W Yenitrisnawati Yogi Aldias Zakariyah Yustinus Denny Ardyanto Wahyudiono Zabidi, Muhammad Azrul Zainon, Muhamad Radzi Zulfa Anida