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All Journal Jurnal Ilmu Dasar Jurnal Penelitian Pendidikan IPA (JPPIPA) Chimica et Natura Acta Indonesian Journal of Chemistry JMM (Jurnal Masyarakat Mandiri) Edukasi Islami: Jurnal Pendidikan Islam Jurnal Kreativitas PKM Molekul: Jurnal Ilmiah Kimia International Journal for Educational and Vocational Studies JCER (Journal of Chemistry Education Research) Kumawula: Jurnal Pengabdian Kepada Masyarakat JPPS (Jurnal Penelitian Pendidikan Sains) Jurnal Abdi: Media Pengabdian Kepada Masyarakat Jurnal Abdimas Bina Bangsa Bulletin of Pedagogical Research Jurnal Pijar MIPA Jurnal Pengabdian Teratai Molekul: Jurnal Ilmiah Kimia JUMANDIK Jurnal Akademika Kimia Jurnal Manajemen & Pendidikan Al Ilmu Jurnal Pendidikan MIPA
Tukiran Tukiran
Department of Chemistry, Faculty of Mathematics and Sciences, State University of Surabaya. Jl. Ketintang Surabaya East Java Indonesia-60231.
Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Control & Systems Engineering Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Environmental Science Health Professions Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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Green Synthesis and Characterization Of Silver Nanoparticles using Dadap Serep (Erythrina lithosperma) Leaves Extract as a Bioreductor Albahi, Fairuz Hammad; Sutoyo, Suyatno; Tukiran, Tukiran
Chimica et Natura Acta Vol 14, No 1 (2026)
Publisher : Departemen Kimia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/cna.v14.n1.67126

Abstract

Silver nanoparticles (AgNPs) had been widely applied in various fields such as health, food, environment, catalysts, optics, and electronics. The synthesis of silver nanoparticles can be carried using a  bottom-up method using by bioreductants derived from natural extracts (green synthesis). This study aims to describe the green synthesis of silver nanoparticles using a bioreductants from dadap serep (E. lithosperma)  leaves extract and to determine its characteristics. The synthesis was carried out by varying the volume ratio of dadap serep leaves extract to silver nitrate solution at  ratios of 1: 1, 1: 2, 1: 3, and 1: 4, followed by  optimization at pH 9, 10, and 11. Characterization of the synthesized AgNPs was carried out using Ultra Violet-Visible (UV-Vis) spectrophotometer, Fourier Transform Infrared (FTIR) spectrophotometer, Particle Size Analyzer (PSA), Scanning Electron Microscopy (SEM), and X-Ray Diffraction (XRD). The results showed that the optimum synthesis reaction conditions occurred at a volume ratio of 1: 4 and pH 10. The synthesized silver nanoparticles had an average particle size of 92 nm (DI = 0.3124). The FTIR spectrum showed the presence of hydroxyl groups (3242,88 cm-1), aromatic C=C (1568.35 cm-1), C-O (1033.25 cm-1 ), Ag-O. (519.23  cm-1). The results of XRD analysis showed typical peaks of silver atoms at 2 q: 37.71o (111), 43.84o (200), 64.07o (220), 77.04o (311). SEM analysis showed that the silver nanoparticles had  an irregular surface morphology. Thus, dadap serep (E. lithosperma)  leaves extract has the potential to be used as a bioreductor for the synthesis of silver nanoparticles.
Chemical Profiling of Scoparia dulcis L. Leaf Ethanol Extract and In Silico Antiaging 2Y9X Inhibitor Study Putri, Anjani Fadia; Tukiran, Tukiran
Jurnal Pijar MIPA Vol. 21 No. 2 (2026)
Publisher : Department of Mathematics and Science Education, Faculty of Teacher Training and Education, University of Mataram. Jurnal Pijar MIPA colaborates with Perkumpulan Pendidik IPA Indonesia Wilayah Nusa Tenggara Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jpm.v21i2.11619

Abstract

The intensity of UV radiation that is quite high in the tropics can make the skin age quickly, such as wrinkles, dry, dull skin, or dark spots. In Indonesia, it turns out that 76% of women experience premature aging in this way. The cause is exposure to UVA and UVB radiation, which triggers the production of Reactive Oxygen Species (ROS). Many local plants have been researched for anti-aging, but no one has discussed the anti-aging activity of Scoparia dulcis L. Previous research indicates that Scoparia dulcis L. leaves exhibit antibacterial, antimicrobial, antioxidant, anti-inflammatory, and antidiabetic effects. Therefore, this study aimed to identify potential anti-aging compounds in the ethanol extract of Scoparia dulcis L. leaves as inhibitors of tyrosinase enzyme (PDB ID: 2Y9X), which plays a role in melanin production. Plant material was macerated to preserve flavonoid compounds. Chemical profiling of the extract was analyzed using LC-MS, which identified 104 secondary metabolite compounds. Then, use an in silico approach through molecular docking with AutoDock Vina to evaluate anti-aging compounds in the ethanol extract of Scoparia dulcis L. leaves. The docking results indicated that six compounds showed promising inhibitory potential, with binding affinities better than that of the positive control (-6.0 kcal/mol). These compounds were vanillic acid (-6.2 kcal/mol), caffeic acid (-6.0 kcal/mol), scopoletin (-6.4 kcal/mol), scoparone (-6.2 kcal/mol), jasmonic acid (-6.2 kcal/mol), and budlein A (-6.2 kcal/mol). The six compounds were also analyzed again using Lipinski's Rule of Five so that they could be used as a reference for further experiments for oral drugs. As a result, all of six compounds met that rule and had a smaller bond affinity value than the positive control.
Co-Authors A.A. Ketut Agung Cahyawan W Albahi, Fairuz Hammad Ali Imron Amalia Ruhana, Amalia Ambarwati, Cindy Andika Pramudya Wardhana Bahri, Moh Saiful Biyan Yesi Wilujeng Constanty, Irene Cornelia Dewi, Dyah Utami Dian Anisa Rokhmah Wati ERMAN ERMAN Farkiyah, Lilik Fida Rachmadiarti Firstianto, Seno Aji Hadiwidodo, Suryanto Harun Nasrudin Hendrawan, Syahrul Hendrawan, Syahrul Lerry I GUST MADE SANJAYA Ika Fatmawati Pramasari Irawan, Sani ISMONO ISMONO Kuniyoshi Shimizu Kusumawati Dwiningsih Leny Yuanita Luthfi Faza Afina Riza Walida, Luthfi Mas'ud, Ibnu Meilasari , Renita Meilasari, Renita Mispani, Mispani Mitarlis Mitarlis Mohamad Nur Muchtadin, Muchtadin Muhammad Arhan Rajab MUSLIMIN IBRAHIM Ngubad, Khumaidul Noerlina Anggraeni Nurul Hidajati NURUL HIDAJATI Nurul Hidayati Obing Zaid Sobir Pambudi, Rizdana Galih Pangestu, Puji Dwi Prabowo, Prayudi Setiawan Putri, Anjani Fadia Putri, Pungky Dilaka Raidar, Usman Raihan, Muhammad Ratih Yuniastri Rinaningsih Rinaningsih Rudiana Agustini Saiyidah Mahtari Samik Samik Satriawan, Muhammad Sofyah, Titik Mardiyanti Solly Aryza Sri Hidayati Syarief Sri Yunita Suraida Salat Subagyo, Arif Imam Sumarni Sumarni Sururi, Ahmad Misbakhus Sutoyo, Suyatno Suyatno Suyatno Suyono Suyono Syafi'ah, Rohmatus Syifaiyah, Robiatusy Taufikurahmah, Titik Theodorus Wiyanto Wibowo Wahono Widodo Widjanarko Widjanarko, Widjanarko Widodo Widodo Woro Setyarsih Yuliani, Nuri Yuliani Yuliaturosida, Eka Yunus Yunus Zakiyah, Imroatuz