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All Journal JURNAL PETERNAKAN Jurnal Penelitian Farmasi Indonesia Cetta: Jurnal Ilmu Pendidikan JSFK (Jurnal Sains Farmasi & Klinis) JFIOnline Jurnal Ilmu Kefarmasian Indonesia Community Development Journal: Jurnal Pengabdian Masyarakat TAUJIH: Jurnal Pendidikan Islam Jurnal Farmasi Indonesia Pragmatik : Jurnal Rumpun Ilmu Bahasa dan Pendidikan Causalita: Journal of Psycology Jurnal Pengabdian Masyarakat Jurnal Bakti Nusantara Switch: Jurnal Sains dan Teknologi Informasi Jurnal Kefarmasian Indonesia Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Rahayu Utami
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Religion Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Medicine & Pharmacology Nursing Physics Public Health Social Sciences Other

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UJI INHIBITOR ENZIM TIROSINASE EKSTRAK DAN FRAKSI DAUN KEDABU (Sonneratia ovata Backer) SECARA IN-VITRO Mustika Furi; Ainun Alfatma; Rahma Dona; Armon Fernando; Fina Aryani; Rahayu Utami; Septi Muharni; Husnawati; Wira Noviana Suhery; Melzi Octaviani
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.529

Abstract

Kedabu leaves (Sonneratia ovata Backer) are known contain secondary metabolites, one of which is phenolic, flavonoid and antioxidant activity. Phenolic, flavonoids and antioxidant are known to inhibit the tyrosinase enzyme. The tyrosinase enzyme is involved in the process of melanogenesis which produces melanin. Melanin can cause hyperpigmentation. To prevent hyperpigmentation, tyrosinase inhibitors are needed. This study aimed to test the tyrosinase enzyme inhibitor in ethanol extract, n-butanol fraction, ethyl acetate fraction, n-hexane fraction of kedabu leaf (Sonneratia ovatta Backer) using L-tyrosine as a substrate. The method used to get ethanol extract using ethanol maceration, while some fractions are obtained using the fractionation method. The test was carried out using L-tyrosine and kojic acid as a positive control with absorption measurements using microplate reader at a wavelength of 492 nm. The results showed that the best tyrosinase inhibitory activity was produced by the ethyl acetate fraction with an IC50 value of 18,82 g/mL, followed by the n-butanol fraction with an IC50 value of 24,42 g/mL, and the n-hexane fraction with an IC50 value. 28,77 g/mL, ethanol extract with an IC50 value of 99,09 with a strong category for all samples compared with kojic acid as a positive control with an IC50 value of 30,09 g/mL.
TINGKAT KEPUASAN MASYARAKAT TERHADAP PELAYANAN PENGGALIAN INFORMASI SWAMEDIKASI OLEH PETUGAS APOTEK PADA MASA PANDEMI COVID-19 DI KECAMATAN TUAH MADANI KOTA PEKANBARU TAHUN 2021 Septi Muharni; Putri Zulnandita; Fina Aryani; Rahayu Utami; Mustika Furi
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 8 No. 2 (2022): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v8i2.530

Abstract

Self-medication is an effort made to overcome complaints or pain by using medicines purchased without a doctor's prescription. One of the stages in this self-medication is extracting information. Information gathering aims to collect or dig up information from patients regarding the symptoms experienced by patients so that pharmacy staff are assisted in making decisions and recommending the correct therapy for patients. To determine the quality of information mining services, one way is to find out the community's satisfaction with the self-medication information mining service. Satisfaction is an important part of health services because respondent satisfaction cannot be separated from the quality of health services. The purpose of this study was to determine the level of community satisfaction with the service of extracting information on self-medication and providing drug information by pharmacists during the COVID-19 pandemic in the Tuah Madani sub-district, Pekanbaru City in 2021 based on five (5) dimensions of service quality, namely reliability, responsiveness, empathy, assurance and tangibles. This research is observational/survey research with a descriptive research design using quantitative analysis. Sampling was done by non-probability sampling method on 100 respondents. The results showed that respondents' satisfaction was in the aspect of reliability 66%, responsiveness 76.2%, empathy 74.4%, assurance 75.25% and tangibles 82.12%. This shows that the community as a whole is satisfied with the services provided by pharmacists.
ISOLASI DAN UJI AKTIVITAS ANTIBAKTERI SENYAWA METABOLIT SEKUNDER DARI EKSTRAK METANOL DAUN MARPUYAN (Rhodamnia cinerea Jack.) Musyirna Rahmah Nst; Dwi Andreyas; Rahma Dona; Emrizal; Emma Susanti; Ihsan Ikhtiarudin; Rahayu Utami
Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan Vol. 9 No. 2 (2023): Jurnal Ilmiah Manuntung: Sains Farmasi Dan Kesehatan
Publisher : Sekolah Tinggi Ilmu Kesehatan Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51352/jim.v9i2.671

Abstract

A study on isolation and antibacterial activity of secondary metabolites from the methanol extract of Marpuyan (Rhodamnia cinerea Jack.) Leaves on Escherichia coli has been carried out. Isolation was carried out by column chromatography methods. Whereas the antibacterial activity test was carried out using agar diffusion method. The results of the isolation produced 17.9 mg of RC-F13 isolate compound in the form of light yellow crystals, with a melting point of 170-172oC and soluble in methanol. The results of identification of RC- F13 isolate compounds through testing with AlCl3 reagents, positive including the flavonoid group, were strengthened by the results of the UV spectrum and FT-IR spectrum. Based on the results of the UV spectrum, it was seen that the RC- F13 isolate compound showed λ max 353.60, 257.00 and 209.20 nm. The FT-IR spectrum shows the presence of several functional groups such as OH, C aliphatic C-H, C = O carbonyl, C = C aromatic and C-O. testing the antibacterial activity of methanol extract with a concentration of 20%; 10%; 1%; 0.1% and 0.01%, fraction 13 at 1% concentration; 0.1% and 0.01% and RC- F13 isolate compound concentration of 0.1%, against Escherichia coli bacteria did not show any antibacterial activity which was marked by the absence of clear areas around the disc.
Edukasi Bahaya Konsumsi Minuman Kemasan yang Berlebihan bagi Kesehatan Ginjal Susanti, Emma; Febriana, Mira; Ulfa, Rodia; Utami, Rahayu; Tambunan, Beatrix Evalin; Hanifa, Dhea; Fahri, Elifia Cahyani; Safli, Fazza Aulia; A’dilah, Nur; Afandi, Rifath; Silalahi, Rizka Fitri; Andriani, Sindy; Nurhaliza, Siti; Novianti, Yetri
Jurnal Bakti Nusantara Vol. 2 No. 2 (2024): Jurnal Bakti Nusantara
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/jbn.v2i2.76

Abstract

Gagal ginjal dilaporkan menjadi salah satu penyakit tidak menular yang mematikan. Salah satu faktor penyebab terjadinya gagal ginjal kronis adalah karena mengkonsumsi minuman ringan yang kemasan. Tujuan pengabdian ini adalah mengedukasi masyarakat di Stadion Utama Riau tentang bahaya minuman kemasan yang berlebihan bagi kesehatan ginjal. Metode yang digunakan dalam kegiatan ini adalah ceramah dan diskusi serta pembagian leaflet kepada masyarakat. Pengukuran efektivitas kegiatan sosialisasi ini dilakukan dengan memberikan tes berbentuk kuisoner yang diberikan sebelum kegiatan sosialisasi sebagai tes awal (pretest) dan tes akhir setelah sosialisasi (post-test). Hasil yang diperoleh dari kegiatan ini adalah telah terjadi peningkatan pemahaman peserta tentang bahaya konsumsi minuman kemasan yang berlebihan bagi kesehatan ginjal setelah kegiatan dilaksanakan. Pengetahun yang baik akan bahaya konsumsi minuman kemasan yang berlebihan bagi kesehatan ginjal akan dapat meningkatkan kualitas kesehatan masyarakat.
Cytotoxic activity of isolate compounds from derendan (Lansium parasiticum (Osbeck) K.C. Sahni & Bennet) fruit peel Fadhli, Haiyul; Rahmayanı, Wıky; Allaya, Regina; Jumadila, Ikhsal Mukri; Fernando, Armon; Utami, Rahayu
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 1 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i1.1309

Abstract

Derendan (Lansium parasiticum (Osbeck) K.C. Sahni & Bennet) is a plant from the Meliaceae family that grows in the tropics, especially in Sumatra (Indonesia). It was reported that this plant has antimalarial, antimutagenic, and anticancer properties. This study aims to determine the cytotoxic activity of compounds isolated from the methanol extract of Lansium parasiticum bark. Extraction using maceration method with methanol solvent. Vacuum Liquid Chromatography (KVC) with 21 different eluent ratios (n-hexane : ethyl acetate and ethyl acetate ; methanol) was utilized for the fractionation. The result was 21 fractions. The washing technique was used to purify fraction 17. The obtained compound LPR17 with a melting point of 239-241ᵒC. Based on the UV spectrum, the wavelengths of the LPR17 compound were 277.0 nm and 205.0 nm. The FT-IR spectrum shows aliphatic OH, CH, C=O, C-H, and C-C functional groups. This compound reacts positively with the Liebermann-Burchard reagent. The compound obtained is a triterpenoid group. Cytotoxic test using BSLT method. LPR17 compounds provide very strong cytotoxic activity (LC50 = 67.15 g/mL).
Kadar Flavonoid Total dan Uji In Vitro Aktivitas Tabir Surya Ekstrak Kulit Batang Tuntun Angin (Elaeocarpus floribundus Blume) Utami, Rahayu; Alpasiri, Ikhsan Mauludi; Fadhli, Haiyul; Ikhtiarudin, Ihsan; Mora, Enda; Furi, Mustika
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol. 13 No. 1 (2021): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (359.199 KB) | DOI: 10.35617/jfionline.v13i1.119

Abstract

The stembark of tuntun angin (Elaeocarpus floribundus Blume) has been traditionally using to treat various diseases, including fever, gingivitis and rheumatism. Our previous study has shown that stembark extract of this plant contains significant levels of total phenolics. The aim of this recent study was to determine total flavonoid content and providing an initial determination of sunscreen activity of n-hexane, ethyl acetate and methanol extracts of its stembark. Extraction was carried out by maceration method using three different solvents successively. The quantitative evaluation of total flavonoid content was expressed as mg Quercetin Equivalent (QE)/gram extract at a wavelength of 430 nm using a microplate reader. Evaluation of sunscreen activity was performed by determining value of Sun Protection Factor (SPF) using a UV-Vis spectrophotometer. The results showed that the n-hexane, ethyl acetate and methanol extracts contained total flavonoid levels of 9; 15.81 and 15.56 mgQE/g extract, respectively. Ethyl acetate extract showed the most potential sunscreen activity (ultraprotection category) among other extracts with SPF values of 44.626; 40,687; 33.710 and 23.607 for the tested concentrations of 1000; 800; 600 and 400 µg/mL, respectively. However, this activity is not as good as benzophenone-3 as positive control at a concentration of 50 μg/mL with an SPF value of 22.646 demonstrated an ultraprotection category of sunscreen activity.
Implementation of Student Management in Increasing School Competitiveness at SMP Muhammadiyah 1 Kartasura Utami, Rahayu; Shohib, Muhammad Wildan; Chehdimae, Hamdan
Cetta: Jurnal Ilmu Pendidikan Vol 8 No 3 (2025)
Publisher : Jayapangus Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37329/cetta.v8i3.4222

Abstract

This research aims to determine effective student management in increasing school competitiveness at SMP Muhammadiyah 1 Kartasura. This research is qualitative research that uses the phenomenology approach. Various data collection techniques were used such as direct interviews, field observations, and documentation. The results of the research show that the Deputy Principal for Student Affairs at SMP Muhammadiyah 1 Kartasura applies student management to increase the school's competitiveness through the scope of student management, namely accepting new students, organizing classes, student orientation period, service development, school organization, student and graduate assessment. There are obstacles faced in the form of the difficulty of changing the mindset of students' parents in viewing private schools. So the Deputy Principal for Student Affairs is trying to socialize PPDB and design innovative and creative student programs so that it can display a good image of SMP Muhammadiyah 1 Kartasura.
PENINGKATAN PENGETAHUAN MASYARAKAT MENGENAI KEAMANAN PENGGUNAAN OBAT HERBAL SAAT PUASA DI PUSKESMAS SIAK HULU II KABUPATEN KAMPAR Suhery, Wira Noviana; Almurdani, Muhammad; Nofriyanti, Nofriyanti; Utami, Rahayu; Pratama, Hafizh Yandi; Febbyola, Flara; Wahidah, Lutfiana Nurul; Andrea, Kamilah Dzikra; Azzahra, Fayza Salwa; Anggraini, Hadistri Sekar; Salsabila, Helmaria Putri; Fazira, Intan; Sirait, Indri Hotma Novida; Milianty, Jesy
BESIRU : Jurnal Pengabdian Masyarakat Vol. 2 No. 9 (2025): BESIRU : Jurnal Pengabdian Masyarakat, September 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/besiru.v2i9.1849

Abstract

Pengabdian Masyarakat ini telah dilakukan di Puskesmas Siak Hulu II, Kecamatan Siak Hulu, Kabupaten Kampar, Provinsi Riau. Pengabdian masyarakat ini dilakukan dengan tujuan agar masyarakat dapat mengetahui keamanan penggunaan obat herbal saat berpuasa. Kegiatan dilaksanakan tanggal 14 Maret 2025 di UPTD Puskesmas Siak Hulu II, Kampar, Provinsi Riau. Sasaran dalam kegiatan ini adalah masyarakat yang datang ke UPTD Puskesmas Siak Hulu II, Kabupaten Kampar, Provinsi Riau yang berjumlah 40 orang. Bentuk kegiatan berupa pemberian edukasi lisan terkait dengan keamanan penggunaan obat herbal saat berpuasa dan pembagian brosur sebagai media edukasi. Untuk mengetahui pemahaman masyarakat diberikan pretest dan posttest. Hasil sosialisasi yang dilakukan di Puskesmas UPT II Siak Hulu menunjukkan adanya peningkatan pemahaman masyarakat, dan dapat disimpulkan bahwa kegiatan penyuluhan berjalan dengan baik.
Analisis Sastra Siber Puisi Apa Guna Karya Widji Thukul dalam Platform Youtube dengan Pendekatan Ekspresif Eva Nurhasanah; Rahayu Utami
Pragmatik : Jurnal Rumpun Ilmu Bahasa dan Pendidikan  Vol. 3 No. 2 (2025): April: Pragmatik : Jurnal Rumpun Ilmu Bahasa dan Pendidikan
Publisher : Asosiasi Periset Bahasa Sastra Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61132/pragmatik.v3i3.2086

Abstract

This research was motivated by the author's admiration for Widji Thukul's work and the author's interest in analyzing one of the poems as an extraordinary work because there are many meanings that need to be studied. The purpose of this research is to analyze the cyber literature of Widji Thukul's poem “Apa Guna” in YouTube platform with Expressive Approach. The research method used in this research is descriptive qualitative method, which is a method used to describe the condition of the object naturally, in detail, and systematically at an exclusive time; as well as to find insights, with the researcher as the main instrument in the research. The result of the analysis stated that the cyber literature in the Hyperlink of poem “Apa Guna” by Widji Thukul presented in YouTube platform can be connected with other platforms, such as X, Instagram, Facebook, Whatsapp, and TikTok; and its Hypertext can be connected with poems “Air Kendi”, “Sajak Anak Muda”, “Buku Itu Cahaya”, “Di Negerimu”, “Satu Saat dalam Sejarah”, “Awas”, ‘Soliloquy’, “Menempuh Jalan Rakyat”, “Tanah Sunda”, and poem “Surat Ini Adalah Sebuah Sajak Terbuka”. In the development of technology, the poem “Apa Guna” by Widji Thukul remains relevant to the current situation, both in terms of presentation and the content and meaning of the poem itself. With the literary expressive approach, this poem expresses Widji Thukul's anger, annoyance, and disappointment towards the intellectuals and the rulers, as well as his concern and empathy towards the helpless common people. This is reflected in the diction used in each line of his poem. In the cyber literary context of the poem “Apa Guna”, Hyperlinks and Hypertext help to expand and emphasize the meaning of the poem with inter-platform links and interlinks between other poetry texts.
PEMBUATAN MINUMAN PROBIOTIK TEH KOMBUCHA DARI LIMBAH BONGGOL NANAS (MANUFACTURING PROBIOTIC DRINKS KOMBUCHA TEA FROM PINEAPPLE HUMP WASTE) Firmansyah, Ferdy; Utami, Rahayu; Fitri, Aulia; Asmarani, Asmarani; T, Febry Sesilia; Yani, Halijah Putri; Annur, Isnaini; Alhabil, Laras; Patmawati, Lilis Three; Safitri, Rahtu Janese; Yanto, Rizki Dwi; Rizkia, Tiara; Pratiwi1, Tri Ningtiyas
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 6 No. 1 (2025): Volume 6 No. 1 Tahun 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v6i1.28351

Abstract

Kombucha merupakan minuman hasil fermentasi cairan teh dan gula dengan menambahkan starter mikrobia kombucha yaitu bakteri Acetobacter xylinum dan khamir seperti Saccharomyces cerevisiae, Saccharomyces ludwigii, Saccharomyces bisporus, Zygosaccharomyces sp. Kandungan senyawa kimia yang dihasilkan oleh teh kombucha menjadikan kombucha sebagai minuman fungsional yang memiliki banyak manfaat yang sangat berguna bagi tubuh manusia. Kombucha bermanfaat sebagai antioksidan, antibakteri, memperbaiki mikroflora usus, meningkatkan ketahanan tubuh dan menurunkan tekanan darah. Pengambilan data dilakukan dengan door to door, pembagian leaflet, dan melakukan penyuluhan kepada masyarakat dengan pemberian informasi secara langsung, edukasi secara lisan terkait judul yang diangkat yaitu “Pembuatan minuman probiotik teh kombucha dari limbah bonggol nanas” dan diakhiri dengan pengisian kuisioner terkait pemahaman masyarakat terhadap informasi yang telah disampaikan.Berdasarkan kegiatan yang dilakukan didapatkan hasil bahwa tingkat pengetahuan tiap individu berbeda-beda. Jumlah responden yang didapatkan sebanyak 50 responden. Sebelum melakukan sosialisasi dilakukan kegiatan tanya jawab atau pretest terlebih dahulu guna untuk mengetahui pengetahuan warga selama ini tentang pemanfaatan limbah bonggol nanas sebagai minuman probiotik teh kombucha. Hal itu dapat dilihat dari hasil pengujian statistik menggunakan metode uji Wilcoxon, dimana hasil data yang didapat menunjukkan bahwa adanya hubungan signifikan yaitu dengan meningkatnya skor pengetahuan dari pre-test ke post-test dengan nilai 0,000 yang mana nilai tersebut <0,05.
Co-Authors Afandi, Rifath Ainun Alfatma Alhabil, Laras Allaya, Regina Alpasiri, Ikhsan Mauludi Andrea, Kamilah Dzikra Andriani, Sindy Anggraini, Hadistri Sekar anissa, Siti nurul Annur, Isnaini Ardiyansyah, Roni Armon Fernando Armon Fernando Arsila, Sherly Putri Asmarani, Asmarani Aulia Fitri, Aulia Azzahra, Fayza Salwa A’dilah, Nur Burhan, Shafira Ilma Chehdimae, Hamdan Delvia, Sutri Delvia, Sutri Dwi Andreyas Elza, Bunga Emma Susanti Emrizal Enda Mora Eva Nurhasanah Fahri, Elifia Cahyani Faisya Abrari Lutrinda Fazira, Intan Febbyola, Flara Ferdy Firmansyah Feriansyah, Robby Fina Aryani, Fina Fitri Primawanty Furi, Mustika Haiyul Fadhli Hanifa, Dhea Husnawati Ihsan Ikhtiarudin Ilham Nur Safitri Indah Puspita Sari Jumadila, Ikhsal Mukri M Almurdani Mahasri Shobabiya Masnun, Lidiatil Melzi Octaviani Miftahul Jannah Milianty, Jesy Mira Febriana Muhammad Wildan Shohib Musyirna Rahmah Nasution Musyirna Rahmah Nst Nasution, Musyirna Rahmah Nofri Hendri Sandi Nofriyanti Nofriyanti Novianti, Yetri Novriyenni Novriyenni Nur Rahmadani Fitri Nurul Asma Khoiriyah Oriendhini, Salsa Patmawati, Lilis Three Pitri, Siska Dian Pratama, Hafizh Yandi Pratiwi1, Tri Ningtiyas Putri Lestari, Putri Putri Zulnandita Rachmawati, Fatkur Rahayu, Adnin Rahma Dona Rahmayanı, Wıky rambe, Septy amelia rizki Rasihen, Sri Lidya Rizki Wulandari Rizkia, Tiara Rusmin Saragih, Rusmin Safitri, Rahtu Janese Safli, Fazza Aulia Salsabila, Helmaria Putri Septi Muharni Silalahi, Rizka Fitri Sirait, Indri Hotma Novida Siti Nurhaliza Syilfia Hasti T, Febry Sesilia Tambunan, Beatrix Evalin Ulandari, Bunga Ulfa, Rodia Utami, Adinda Abia Wahidah, Lutfiana Nurul Wira Noviana Suhery Yani, Halijah Putri Yanto, Rizki Dwi Yayuk Riana