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Identification and Characterization of Volatile Compounds in Antidesma bunius (Buni) Fruit Kombucha During Fermentation Wulansari, Nadya Treesna; Dharmapatni, Ni Wayan Kesari; Damayanti, Ida Ayu Manik; Raningsih, Ni Made
Sciences of Phytochemistry Volume 5 Issue 2 (2026)
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphy0501676

Abstract

Buni fruit (Antidesma bunius) is a fruit commonly found in tropical countries such as Indonesia. This fruit has the potential to be developed into kombucha tea because it contains beneficial bioactive compounds. However, the use of buni fruit as kombucha tea remains very limited and has not been studied in depth. The objective of this study was to identify and characterize the volatile compounds in buni fruit kombucha using GC-MS. This study employed a descriptive experimental design to analyze the volatile compounds in buni fruit kombucha after 8 days of fermentation using GC-MS. Buni fruit kombucha fermented for 8 days produced a dark purple color. Based on the analysis of volatile compounds, buni fruit kombucha was identified as containing 30 volatile compounds. The dominant compounds were hexadecanoic acid methyl ester, hexadecanoic acid ethyl ester, 9-octadecenoic acid methyl ester, (E)-9-octadecenoic acid ethyl ester, octadecanoic acid ethyl ester, eicosanoic acid ester, and docosahexaenoic acid methyl ester, which are classified as fatty acid esters and lipids. Additionally, the identified alcohol compounds are patchouli alcohol and 13-tetradecen-11-yn-1-ol. Buni fruit kombucha tea undergoes chemical transformations characterized by the formation of volatile compounds such as esters, alcohols, and fatty acid derivatives as a result of microbial metabolic activity. The profile of the resulting compounds highlights the important role of biotransformation during fermentation in shaping the sensory characteristics and bioactive potential of kombucha tea.
Characterization of Gomphrena globosa L. Flower Extract and Anti-Acne of Formulated Cream Against Cutibacterium acnes Wuryanto, Stefani Alya Swasa; Damayanti, Ida Ayu Manik; Indrayoni, Putu
Sciences of Pharmacy Volume 5 Issue 3 (2026)
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0502675

Abstract

Cutibacterium acnes is a cause of acne. Conventional treatments often lead to side effects and bacterial resistance, necessitating natural alternatives. Globe Amaranth (Gomphrena globosa L.) shows potential as an anti-acne agent. This study employed an in vitro experimental laboratory design to evaluate the anti-acne activity of G. globosa L. flower extract formulated cream against C. acnes using the well diffusion method. Antibacterial activity was tested using KN (base cream), KP (1% clindamycin cream), F1 (10%), F2 (15%), and F3 (20%), and the data were analyzed using SPSS statistical analysis. Results indicated that the ethanolic extract of GA flowers has an IC50 of 85.483 ppm, TPC of 60.456 ± 0.589 mg GAE/g, and TFC of 34.390 ± 0.989 mg QE/g. It exhibited antibacterial activity against C. acnes, with inhibition zone diameters of 6.693 ± 0.2 mm for the 15% formula and 7.382 ± 0.22 mm for the 20% formula. The antibacterial activity is believed to be driven by the presence of secondary metabolites, particularly phenols and flavonoids identified in the extract.
STUDI GAYA HIDUP MAHASISWA TERKAIT FAKTOR RISIKO PENYAKIT GINJAL KRONIK (PGK) Ni Wayan Kesari Dharmapatni; Ida Ayu Manik Damayanti; Nadya Treesna Wulansari; Ni Wayan Sukma Antari
The Shine Cahaya Dunia S-1 Keperawatan Vol. 9 No. 2 (2024): THE SHINE CAHAYA DUNIA S-1 KEPERAWATAN
Publisher : LPPM Universitas An Nuur

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35720/

Abstract

 Latar Belakang : Penyakit Ginjal Kronik (PGK) telah menjadi masalah kesehatan masyarakat yang terus berkembang. Tidak hanya pada lanjut usia, kasus PGK di kalangan dewasa muda telah meningkat selama beberapa tahun terakhir di Indonesia. Hal ini dikarenakan adanya pergeseran gaya hidup di kalangan generasi muda. Beberapa aspek gaya hidup ditemukan menjadi faktor risiko tinggi untuk terjadinya PGK.   Metode : Penelitian ini menggunakan design descriptive analitic dengan pendekatan cross sectional. Pengumpulan data dilakukan melalui survei kuesioner dan pengukuran antropometri, tekanan darah, dan gula darah sewaktu (GDS) terhadap 316 responden dengan metode purposive sampling. Analisis data menggunakan uji univariat.   Hasil : Dari total 316 responden mayoritas merupakan laki-laki (54.7%), memiliki IMT normal (48.1%), tekanan darah sistolik normal (46.8%), tekanan darah diastolik normal (61.1%), dan GDS normal (100%). Berdasarkan gaya hidup, lebih dari setengah responden tidak merokok (50.6%) dan konsumsi makanan tinggi gula (50.6%). Responden juga konsumsi makanan tinggi garam (56%), olahan/berminyak (61.4%), sayur/buah (74.4%) tetapi tidak setiap hari. Selain itu, responden melakukan aktivitas fisik kurang dari 30 menit perhari (60.1%) dan tidak minum alkohol satu bulan terakhir (88%).   Kesimpulan : Gaya hidup mahasiswa saat ini menunjukkan berbagai tantangan yang berkaitan dengan kesehatan. Pola makan yang tidak sehat, kurangnya aktivitas fisik, serta kebiasaan merokok dan konsumsi alkohol merupakan faktor-faktor utama yang memengaruhi kesehatan mahasiswa. Untuk itu, perlu ditingkatkan kembali penyebaran informasi kesehatan dikampus dan menyediakan fasilitas olah raga yang mendukung. 
Co-Authors A.A. Istri Mas, Padmiswari A.A.S. A. Sukmaningsih AA Istri Mas Padmiswari Abda Abda Adiana, I Nengah Adnyana, I Kadek Budi Anak Agung Istri Mas Padmiswari Ariani, Ni Komang Sri Aristadewi, Ida Ayu Mas Artana, I Wayan Budi Artha, I Wayan Oktapratama Asthadi Mahendra Bhandesa, Asthadi Mahendra Clarisa, Gusti Ayu Della Deni Redita, I Komang Dira, Made Asmarani Dwi Arymbhi Sanjaya Gede Surya Indrawan Gede, Surya Indrawan Gusti Ayu Della Clarisa I Gusti Agung Tresna Wicaksana I Ketut Alit Adianta I Ketut Junitha I Ketut Swarjana I Made Bayu Jaya Kusuma I Putu Artawan I Putu Gde Yudara Sandra Putra I Putu Gede Sutrisna I Putu Gede Sutrisna . I Wayan Budi Artana Ida Bagus Made Suaskara Ida Bagus Separsa Kusuma Kadek Buja Harditya Kadek Buja Harditya Kadek Maya Cyntia Dewi Kadek Nuryanto Lumbantobing, Gita Vidya Natalia Maha Putra, I Nyoman Arya Mahaputra, I Nyoman Arya Mas Aristadewi, Ida Ayu Nadya Treesna Wulansari Nadya Treesna Wulansari Ni Luh Adi Satriani Ni Luh Putu Inca Buntari Agustini Ni Made Ayu Sukma Widyandari Ni Made Krisna Ayu Lestari Ni Wayan Ayu Eka Perantini Ni Wayan Desi Bintari Ni Wayan Kesari Dharmapatni Ni Wayan Sukma Antari Ni Wayan Sukma Antari Ni Wayan Sukma Antari Ni Wayan Sukma Antari, Ni Wayan Sukma Antari Nuryanto, Kadek Nyoman Eta Risnawati Padmiswari, A.A Istri Mas Padmiswari, A.A. Istri Mas Pramana, I Kadek Bagus Ari Putu Ekawati Ida Ayu Putu Indrayoni Putu Rima Sintyadewi Raningsih, Ni Made Sanjana, I Wayan Sri Dewi Megayanti Sri Dewi Megayanti Sri Idayani Sri Idayani Strisanti, Ida Ayu Suptika Sukaningsih, Ni Wayan Sutrisna , I Putu Gede Sutrisna, Putu Gede Suweca, I Gede Tohir, Wa. Aniyda M. Wahyunadi, Ni Made Dewi Wicaksana, IGA Tresna Widiatmaja, Gusti Panji Widyas Pranata, Gst. Kade Adi Wulansari , Nadya Treesna Wuryanto, Stefani Alya Swasa Zabrina, Putu Tiara