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Journal : Bioscientia Medicina : Journal of Biomedicine and Translational Research

Passive Smoking as a Significant Risk Factor of Cervical Dysplasia: A Novel Findings in Single Center Study in Denpasar, Bali, Indonesia Pradnyana, I Wayan Agus Surya; Mirani Ulfa Yusrika; I Gusti Bagus Mulia Agung Pradnyaandara; I Gde Sastra Winata
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 8 No. 11 (2024): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v8i11.1126

Abstract

Background: Colposcopy is a diagnostic procedure evaluating the cervix following an abnormal screening test. It aims to identify and treat cervical cancer precursors. Risk stratification at the end of colposcopy helps differentiate those who can return to regular screening from those needing more frequent screening or surveillance. The study examined the characteristics and risk factors of patients undergoing colposcopy for cervical dysplasia in Denpasar, Bali, Indonesia. Methods: This was a cross-sectional study of women who underwent colposcopy at BaliMed Hospital, Denpasar, Bali, Indonesia, from January 2021-December 2022. Data were derived from medical records. The gynecology oncologist performed a colposcopy examination with a biopsy sample, which was later checked by the pathologist. Bivariate and multivariate analyses were used to identify the risk factors associated with cervical dysplasia. Results: 142 patients underwent colposcopy with a mean age of 37.28+10.1 years. Seventy-eight patients (54.9%) had a low-grade cervical lesion, and 9 (6.3%) had a high-grade cervical lesion. After adjusting the employment status and education level, factors associated with cervical dysplasia were age at first intercourse <20 years (aOR [adjusted odd ratio] 2.44, 95% CI [1.04-5.69]) and history of smoking, either actively or passively (aOR 8.91, 95% CI [3.52-22.54]). From the biopsy result, patients with abnormal cervical lesions were associated with evidence of CIN (aOR 9.03, 95% CI [2.49-32.77]). Conclusion: Early age first sexual intercourse and history of smoking have been identified as significant risk factors for cervical dysplasia. Additionally, passive smoking has been shown to increase the risk. This research provides a foundational reference for future studies in this area.
Co-Authors A.A.N. Anantasika Anak Agung Gede Putra Wiradnyana Anak Agung Ngurah Anantasika Anthony Stephen Halim Arlando Martino Anapaku Charles Richard Thene Clara Amanda Daniel Hadinata Susanto Desak Putu Oki Lestari Dewi, Putu Pradnya Paramitha Dolesgit, Ni Made Garnis DPG Jananuraga Maharddhika Endang Sri Widiyanti Eric Gradiyanto Ongko Ernest T. B. Sianturi Ernest TB Sianturi Felyanto, Felyanto Fenyta Christyani FLORENCIA Florencia Desiree Florencia Desiree I Gede Indra Kumara I Gede Mahendra Adiguna Dira I Gede Mega Putra I Gusti Ayu Putri Kartika, I Gusti Ayu I Gusti Bagus Mulia Agung Pradnyaandara I Ketut Surya Negara I Ketut Suwiyoga I Made Darmayasa I Nyoman Bayu Mahendra I Nyoman Gede Budiana I Nyoman Gede Budiana I Nyoman Hariyasa Sanjaya I Wayan Agus Surya Pradnyana I Wayan Artana Putra I Wayan Megadhana I Wayan Parsa Ida Bagus Arjuna Ida Bagus Gde Fajar Manuaba IGN. Wiranta Permadi Ika Widi Astuti, Ika Widi Ines Kurniaty Hartono Johan Qalaba Kade Yudi Saspriyana Kade Yudi Saspriyana Ketut Suwiyoga Kevin Agastya Duarsa Lazarosony, Nicholas Renata Made Ayu Prabawaty Indraswari Made Bagus Dwi Aryana Made Yudha Ganesa Wikantyas Widia Maria Septiana Parmonang Aroean Mirani Ulfa Yusrika Musa Taufiq Musa Taufiq Ngakan Ketut Darmawan Ni Luh Wita Astari Widhusadi Ni Wayan Armerinayanti Nicholas Renata Lazarosony Nicholas Renata Lazarosony Nyoman Bayu Mahendra Ongko, Eric Gradiyanto Pande Kadek Aditya Prayudi Pande Kadek Aditya Prayudi Pande Made Suwanpramana Paskarani, Putu Erika Piere Emanuel Yoltuwu Piers Andreas Noak Pradnyana, I Wayan Agus Surya Putu Bagus Darmayasa Putu Doster Mahayasa Putu Harrista Indra Pramana Rayvany Uil Ryan Saktika Mulyana Sitohang, Elisa Laura Oktrinita Sucitawati, Putu Devita Tjokorda Gde Agung Suwardewa Wibawa, I Gusti Ngurah Agung Satria William Alexander Setiawan Yuliantini, Sang Ayu Putu