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All Journal Archive of Community Health Jurnal Veteriner Prosiding Seminar Nasional MIPA Jurnal Vektor Penyakit WMJ (Warmadewa Medical Journal) JBN (Jurnal Bedah Nasional) Jurnal Kesehatan Medika Udayana Aesculapius Medical Journal Public Health and Preventive Medicine Archive Jurnal Ilmu Kesehatan Masyarakat
K Tangking Widarsa
Program Studi Ilmu Kesehatan Masyarakat, Fakultas Kedokteran Universitas Udayana
Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Pemberian Ekstrak Methanol Daun Paliasa Menurunkan Kadar Glukosa Darah Tikus Hiperglikemik (METHANOL EXTRACT OF PALIASA LEAVES DECREASES BLOOD GLUCOSE LEVEL HYPERGLYCEMIC RATS ) Yuliana .; Tangking Widarsa; Gede Wiranatha
Jurnal Veteriner Vol 14 No 4 (2013)
Publisher : Faculty of Veterinary Medicine, Udayana University and Published in collaboration with the Indonesia Veterinarian Association

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Abstract

Diabetes melitus is a disease that often encountered by Indonesian people. It can cause microvascular andmacrovascular complication. Traditional herbal medicine such as paliasa (Kleinhovia hospita L.) leavesextract can decrease blood glucose. This study was aimed to identify the effectiveness of extract paliasaleaves on blood glucose decreasing for aloxan induced Wistar mice. This Control Group Design used twentyeight mice (three months old). The mice were divided randomly into four groups, i.e. control, paliasa250mg/kg body weight (BW), 500 mg/kg BW, and 750 mg/kg BW. After one week adaptation and induced byalloxan, pretest fasting blood glucose test was done. Treatment was given for two weeks and posttest bloodglucose test was done afterwards. The decrease of fasting blood glucose level was analyzed by usinganalysis of varians. Result showed there was significantly higher level of blood glucose decrease in micewith paliasa extract dose of 750mg/kgBB. Mean level of blood glucose decrease on control group was2.9±0.17, paliasa group with dose 250mg/kgBB was 29.28±1.15, paliasa 500 mg/kgBB was 46.7±2.1, danpaliasa 750mg/kgBB was 74.8±1.88.  In conclusion, extract paliasa treatment can decrease fasting bloodglucose level on hyperglycemic rats.
Hubungan Frekuensi Gen Knock-Down Resistance (KDR) V1016G, V410L, dan F1534C dengan Tingkat Resistensi Populasi Aedes aegypti di Denpasar, Bali Erly Sintya; Kartika Sari; Ni Wayan Widhidewi; Ni Made Hegard Sukmawati; Ni Putu Diah Witari; Tangking Widarsa
Jurnal Vektor Penyakit Vol 15 No 2 (2021): Edisi Desember
Publisher : Balai Penelitian dan Pengembangan Kesehatan Donggala, Badan Penelitian dan Pengembangan Kesehatan, Kementerian Kesehatan RI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22435/vektorp.v15i2.4907

Abstract

ABSTRACT Insecticides are used to reduce the number of Aedes aegypti mosquitoes, a vector of the dengue virus that causes dengue hemorrhagic fever in Indonesia, including in Bali. However, in recent years, the resistance of the Ae. aegypti mosquito to insecticides has been reported in Bali. In addition, Ae. aegypti is also identified to be resistant to several types of insecticides whose resistance mechanism is not yet clear. Several studies have stated that the KDR genes are one of the causes of resistance to pyrethroid insecticides. Therefore, a study was conducted to determine the frequency of the KDR genes in the Ae. aegypti population in Denpasar, Bali which had been previously shown resistance to permethrin (type of pyrethroid). Forty-three females Ae. aegypti specimens from bioassay testing using permethrin stored in tubes containing 100% ethanol were used in this study. Each mosquito is put in a different tube. The mosquito DNA was then extracted. Three KDR genes, V1016G, V410L, and F1534C, were analyzed using the quantitative-PCR melt curve method at the Biomolecular Laboratory, FKIK Unwar. In this study, the mutation frequency of 1016G was 98%, 410L was 50%, and 1534C was 3.4%. The 410L mutant gene was shared by all specimens, although only in one allele (heterozygous). Of the 43 specimens, 39 had homozygous mutant V1016G, heterozygous V410L, and wild typehomozygous F1534C. It indicated that the frequency of the 1016G and 410L mutant genes is quite high, while the 1534C gene is low. The combination of the KDR 1016G and 410L genes was the most dominant found in permethrin-resistant Ae. aegypti specimens. Therefore, it is assumed that these two KDR genes play a role in forming permethrin resistance in Ae. aegypti. ABSTRAK Insektisida digunakan untuk menurunkan jumlah nyamuk Aedes aegypti yang merupakan vektor virus dengue penyebab penyakit demam berdarah dengue di Indonesia, termasuk di Bali. Namun, dalam beberapa tahun terakhir, resistensi nyamuk Ae. aegypti terhadap insektisida dilaporkan sudah terjadi di Bali. Selain itu, Ae. aegypti juga dilaporkan resisten terhadap beberapa jenis insektisida yang mekanisme terjadinya resistensi belum diketahui. Beberapa penelitian menyebutkan bahwa gen KDR menjadi salah satu penyebab terjadinya mekanisme resistensi terhadap insektisida golongan peritroid. Oleh sebab itu, dilakukan penelitian untuk mengetahui frekuensi gen KDR pada populasi Ae. aegypti di Denpasar, Bali yang sebelumnya telah terbukti memiliki resistensi permetrin (insektisida golongan peritroid). Sebanyak 43 spesimen Ae. aegypti betina hasil dari pengujian bioassay yang tersimpan dalam tabung yang berisi etanol 100% digunakan dalam penelitian ini. Tiap nyamuk dimasukkan dalam tabung yang berbeda. Selanjutnya dilakukan ekstraksi DNA nyamuk. Tiga jenis gen KDR, yaitu V1016G, V410L, and F1534C, dianalisis dengan metode quantitative-PCR melt curve di Laboratorium Biomolekuler FKIK Unwar. Dalam penelitian ini ditemukan frekuensi mutasi 1016G sebesar 98%, 410L 50%, dan 1534C sebesar 3,4%. gen mutan 410L dimiliki oleh seluruh spesimen walaupun hanya pada salah satu alel (heterozigot). Dari 43 spesimen yang diteliti, terdapat 39 spesimen yang memiliki profil genotip V1016G homosigot mutan, V410L heterosigot, dan F1534C homosigot wild type. Sehingga dapat disimpulkan bahwa frekuensi gen mutan 1016G dan 410L cukup tinggi, sedangkan gen 1534C rendah. Kombinasi gen KDR 1016G dan 410L paling dominan ditemukan pada spesimen Ae. aegypti resisten permetrin. Kedua gen KDR diasumsikan berperan dalam pembentukan resistensi permetrin pada Ae. aegypti.
PROFIL ASAM AMINO EKSTRAK SEREDELE DAN TEMPE KEDELAI, MAKANAN TRADISIONAL HASIL FERMENTASI N K Sutiari; K Tangking Widarsa; A Swandewi; P Widarini
Prosiding Seminar Nasional MIPA 2011: PROSIDING SEMINAR NASIONAL MIPA UNDIKSHA 2011
Publisher : Prosiding Seminar Nasional MIPA

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Abstract

Abstrak: Makanan yang mengalami proses fermentasi diyakini dapat memberikan manfaat bagi kesehatan manusia. Proses kedelai yang difermentasi menyebabkan kedelai mudah untuk dicerna dan mampu menghilangkan bau dan rasa langu serta berpotensi mengandung komponen zat gizi yang belum banyak dieksplorasi. Penelitian ini bertujuan untuk menganalisis komposisi profil asam amino ekstrak seredele dan ekstrak tempe. Penelitian ini bersifat eksperimental dengan sampel sebanyak 2 jenis bahan makanan terfermentasi yaitu seredele dan tempe kedelai. Sampel tersebut dibuat dalam bentuk ekstrak dan selanjutnya dianalisis komposisi asam amino dengan metode HPLC. Asam amino yang diujikan adalah sejumlah 15 asam amino           . Hasil peneltiian menun-jukkan bahwa kedua kstrak bahan makanan yaitu ekstrak seredele dan tempe kedelai mempunya komposisi asam amino yang bervariasi dan cukup lengkap dengan 15 asam amino esensial. Seredele yang merupakan makanan khas tradisional Bali memiliki kandungan asam glutamate (glutamic acid) yang lebih tinggi dibandingkan dengan ekstrak tempe, yaitu masing-masing 0.6% dan 0.4%. Kandungan asam amino Aspartic acid dan Tyrosine pada seredele juga ditemukan lebih tinggi daripada tempe kedelai. Adanya kandungan asam amino jenis asam glutamate (Glutamic Acid) yang lebih tinggi dari tempe menunjukkan potensi atau kemampuan untuk mengikat zat besi. Untuk itu disarankan adanya suatu penelitian lanjutan mengenai kemampuan atau potensi mengikat zat besi dari seredele dan tempe kedelai secara in vitro
Faktor Sosial Ekonomi Kematian Bayi di Dusun Muntigunung Kabupaten Karangasem Provinsi Bali Ni Luh Putu Suariyani; I Ketut Tangking Widarsa; Ni Putu Widarini; Ni Ketut Sutiari; Rina Listyowati
Jurnal Ilmu Kesehatan Masyarakat Vol. 1 No. 3 (2010): Jurnal Ilmu Kesehatan Masyarakat
Publisher : Association of Public Health Scholars based in Faculty of Public Health, Sriwijaya University

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Abstract

Latar belakang: Dusun Muntigunung merupakan daerah kritis di Karangasem dengan jumlah penduduk miskin yang tinggi dan angka kematian bayinya paling tinggi di Karangasem. Sehubungan dengan masalah tersebut maka penelitian ini bertujuan untuk mengidentifikasi faktor determinan kematian bayi yang potensial di Muntigungung.Metode : Penelitian ini dirancang sebagai penelitian deskriptif ekploratif dengan pendekatan kualitatif berupa studi kasus Dusun Mutigungung dengan menggunakan keluarga yang memiliki kematian bayi satu atau lebih dalam 5 tahun terakhir sebagai kasus. Data kelahiran, kematian bayi, pendidikan, pekerjaan ibu, penghasilan keluarga serta keadaan geografis dikumpulkan dengan wawancara mendalam dan observasi. Hasil wawancara direkam dan dibuatkan transkripnya. Transkrip hasil wawancara dianalisis secara kualitatif sesuai konten factor determinan kematian bayi.Hasil : Dari 8 kasus kematian bayi dari 5 sampel keluarga, 6 meninggal waktu lahir, satu pada umur 2 hari dan satu lagi pada umur 2 bulan. Kemungkinan kematian tersebut disebabkan oleh aspiksia atau infeksi dan meninggal sebelum diobati ke dokter/bidan. Dimana keluarga tersebut memiliki faktor sosial ekonomi yang rendah.Kesimpulan: Faktor sosial-ekonomi keluarga yang meliputi pendidikan ibu dan suami serta pendapatan keluarga yang rendah kemungkinan salah satu faktor penyebab kematian bayi.Kata kunci: Sosial ekonomi, pendidikan, pendapatan, kematian bayi
Hubungan Lama Penggunaan Gadget dengan Gangguan Pola Tidur pada Anak Sekolah Dasar Kelas 4 Sampai 6 di Denpasar A. A. Ayumi Witantri; Sagung Putri Permana Lestari MP; I Ketut Tangking Widarsa
AMJ (Aesculapius Medical Journal) Vol. 2 No. 2 (2022): August
Publisher : Fakultas Ilmu Kedokteran dan Ilmu Kesehatan, Universitas Warmadewa

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Abstract

Gadget adalah satu dari sekian perkembangan teknologi masa kini yang diminati seluruh kalangan usia tak terkecuali anak sekolah dasar. Gadget dapat memberi dampak negatif jika digunakan dalam durasi yang lama, yakni gangguan pola tidur. Tujuan penelitian yakni mengidentifikasi mengenai hubungan lama penggunaan gadget dengan gangguan pola tidur pada anak sekolah dasar kelas 4 sampai 6 di Denpasar. Desain yang dipakai yakni analitik korelasi dan rancang cross sectional, dengan subjek seluruh anak sekolah dasar kelas 4 sampai 6 di Denpasar yang telah memenuhi kriteria. Penelitian dilakukan dari bulan September 2021 sampai bulan Mei 2022 dengan teknik pengambilan data purposive sampling dan instrumen penelitian berupa kuesioner. Data dianalisis dengan univariat distribusi frekuensi serta analisis bivariat chi-square. Hasil akhir bivariat mendapatkan nilai p = 0,00 dengan nilai r = 0,4 (koefisien korelasi), menjelaskan bahwa nilai kolerasi linear variabel lama penggunaan gadget pada pola tidur memiliki korelasi positif dan hubungannya rendah. Berdasarkan hasil nilai korelasi dapat diketahui nilai koefisien determinasi (r2 = 0,16), hal ini menunjukkan bahwa sebesar 16% variabel lama penggunaan gadget mempengaruhi gangguan pola tidur, sisanya sebanyak 84% dipengaruhi oleh faktor lain yang tidak ada dalam model penelitian.
Community Survey on Blood Pressure and Levels of Blood Glucose, Cholesterol and Uric Acid Among People 45 Years and Above in Rural Villages of Bali Putu Sutisna (Scopus ID: 6506044199); I Ketut Tangking Widarsa; I Wayan Darwata; I Nengah Kapti
WMJ (Warmadewa Medical Journal) Vol 7 No 2 (2022): November 2022
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.7.2.4903.47-54

Abstract

OBJECTIVE. To observe the proportion of high blood pressure and high blood glucose, cholesterol and uric acid among people aged 45 years and older at the rural villages of Pejeng, Samplangan and Petak, in Gianyar Regency, Bali. METHODS. The survey’s samples were all persons aged 45 years and over who came voluntarily to participate in the survey. Blood pressure was measured by mercury sphygmomanometer (Nova). Non-fasting levels of serum glucose, cholesterol, and uric acid were assessed by rapid test method using Easy Touch CGU apparatus. Each parameter studied was categorized as “high” and “normal” (blood pressure high: ≥140/90 mmHg; blood cholesterol high: ≥200mg/dl; blood glucose high ≥200mg/dl; blood uric acid high: >7.0 mg/dl, while other measurements below those values were categorized as normal. Data were analyzed descriptively and presented in tables of frequencies. RESULTS. A total of 650 people aged 45 years and above participated in the survey (Samplangan village: 157 people, Pejeng village: 168 people, Petak village: 225 people). Of 650 study subjects examined, 43.8% had high serum cholesterol, 22.8% had high blood pressure, 26.3% had high serum uric acid, and 9.8% had high blood glucose. According to gender, 49.5% males and 38.2% females had high blood cholesterol, 27.3% males and 20.5% females had high blood pressure, 38.4% males and 20.3% females had high blood uric acid, and 11.1% males and 9.4% females had high blood glucose, respectively CONCLUSIONS. In respective three villages greatest proportion of the study subjects had high serum cholesterol, followed in order of decreasing proportions by either high blood pressure or high blood uric acid, and the lowest proportion was with high blood glucose.
Anemia among pregnant women first and second trimester increases risk for low birth weight babies in Wangaya Hospital, Denpasar I Ketut Labir; I Ketut Tangking Widarsa; Ketut Suwiyoga
Public Health and Preventive Medicine Archive Vol. 1 No. 1 (2013)
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53638/phpma.2013.v1.i1.p05

Abstract

Low birth weight is one of the major contributors to infant mortality rate (IMR). One of the dominant risk factors for the low birth weight is anemia. This study aimed to investigate the effect of anemia in pregnant women at first and second trimester to the incidence of low birth weight at Wangaya Hospital Denpasar. This study is a retrospective cohort design. The total samples were 150 respondents; 50 pregnant women with anemia in the first trimester, 50 pregnant women with anemia in the second trimester and 50 pregnant women without anemia. Samples were taken from medical records at Wangaya Hospital Denpasar using simple random sampling method. Data were collected by documentation study and data analysis was done using logistic regression. The results showed that pregnant women with anemia in the first trimester were having a risk of 10 times to give low birth weight compared to pregnant women who are not anemia [RR=10.29; 95%CI: 2.21-47.90], whereas pregnant women with anemia in the second trimester were at risk 16 times greater of having a low birth weight baby compared to pregnant women who are not anemia [RR=16; 95%CI: 3.49-73.41]. There was no difference in the incidence of low birth weight among anemia first and second trimester [p=0.297]. We can conluded that anemia among pregnant women in the first and second trimester increased the risk of low birth weight. The results of this study can be used by policy makers to planning prevention strategies to reduce the incidence of low birth weight babies including intensify the antenatal care program for pregnant women.
Factors related to parent’s participation in child dental health care in Tegallalang I Public Health Centre Vivin Sumanti; I Ketut Tangking Widarsa; Dyah Pradnyaparamita Duarsa
Public Health and Preventive Medicine Archive Vol. 1 No. 1 (2013)
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53638/phpma.2013.v1.i1.p08

Abstract

The public health centre reports showed that the level of parent’s participation in children dental health care in Tegallalang I Public Health Centre was low (31.7%-35.1%). This study aims to determine the relationship between parent’s knowledge, attitudes, motivation and transportation accessibility to parent’s participation in child dental health care in Tegallalang I Public Health Centre. A cross-sectional study was conducted to 100 parents whose children were referred to undergo dental health examinations in Tegallalang I Public Health Centre using a systematic random sampling method. Data of knowledge, attitudes, motivation and transportation accessibility were collected using an interview guide, while parent’s participation was obtained from dental care registration. The data were analised by logistic regression. The results showed that level of parent’s participation in child dental health care was low (41%). Variables that were significantly associated with level of parent’s participation in child dental health care were knowledge [OR=7.35; p=0.001], motivation [OR=4.89; p=0.028] and attitudes [OR=4.19; p=0.039). Transport accessibility was not associated with parent’s participation [OR=2.35; p=0.123]. The conclusion of this study is that parent’s participation in child dental health care was influenced by parent’s knowledge about oral health, motivation and attitudes towards child dental health care. It is recommended to upscale health promotion related to dental health and the benefits of treatment in order to encourage parent’s participation in children dental health care.
Risk factors of type 2 diabetes mellitus of outpatients in the community health centres of South Denpasar Subdistrict Sri Trisnawati; I Ketut Tangking Widarsa; Ketut Suastika
Public Health and Preventive Medicine Archive Vol. 1 No. 1 (2013)
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53638/phpma.2013.v1.i1.p14

Abstract

The prevalence of Diabetes Mellitus (DM) is increasing throughout the world particularly type 2 DM. The changes in people’s lifestyle and diets are assumed to play major roles. This study aimed to examine the relationships between the risk factors such as obesity based on body mass index (BMI) and waist circumference (WC), hypertension, inactivity, smoking, and age ≥50 years with the incidence of type 2 DM. A matched case-control design involving of 136 pairs of men with family history of diabetes was used in this study. Cases and controls were selected from outpatients at the South Denpasar Sub-District Public Health Center. Data from outpatients were collected by interviewing, physical and laboratory examinations. Data were analyzed using McNemar and logistic regression. Based on the statistical analysis the Odds Ratio (OR) of the factors such as obesity (based on waist circumference) was 5.2 [95%CI: 2.31-11.68] with p=0.001 and age ≥50 years was 4 [95%CI: 1.74-9.21] with p=0.001. It can be concluded that patients with obesity (based on waist circumference) and age of ≥50 years have a higher risk for type 2 DM. It suggested that the occurrence obesity in the community can be reduced by modifying the lifestyle and eating patterns of the community.
Risk factors of maternal mortality due to complications in pregnancy, delivery and postpartum in Bima Regency 2011–2012 Sri Juharni; I Ketut Tangking Widarsa; Dewa Nyoman Wirawan
Public Health and Preventive Medicine Archive Vol. 1 No. 2 (2013)
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53638/phpma.2013.v1.i2.p05

Abstract

The maternal mortality rate (MMR) in West Nusa Tenggara Province in 2010 is about 350/100,000 live births. This figure is higher than national and other provincial figures. Bima that constitutes a regency of West Nusa Tenggara Province has high maternal mortality cases for period of 2011-2012, namely 20 cases. The Ministry of Health classified 3 factors that affect maternal mortality, namely: medical, non-medical and health service factors. The study was aimed at finding out the risk factors that affect maternal mortality. This study is a case control study with the total samples of 20 cases and 60 controls. The data were collected through interviews by using the questionnaires. The collected data were then cross-checked with the registers existing at midwives, health record cards of pregnant women and verbal autopsy documents. The univariate, bivariate and multivariate analyses were done. Bivariate analysis was using chi square test and multivariate analysis was using logistic regression. The study revealed that factors which increase the maternal mortality rate are the level of Hb<10 gr% (OR=15.19; 95%CI: 3.25–70.97), delayed decision-making (OR=9.28; 95%CI: 2.15–84.80) and delayed medical treatment at referral facilities (OR=13.16; 95%CI: 2.28–104.86). As conclusion, the most contributing factor to maternal mortality is the level of Hb<10 gr%. The efforts to reduce mortality rate should be conducted including increasing Hb level of pregnant women, improving basic obstetric emergency handlings at community health centres for midwives/medical doctors and to improve better referral systems.
Co-Authors A Swandewi A. A. Ayumi Witantri Bharata, Made Dwi Yoga Bunganing Eswarya Cokorda Istri Padmi Desak Nyoman Widyanthini Dewa Ayu Agung Alit Suka Astini Dewa Nyoman Wirawan Dewa Nyoman Wirawan, Dewa Nyoman Dwi Masu Putra Dyah Pradnyaparmita Duarsa Erly Sintya Febianingsih, Ni Putu Eka Gede Wiranatha Gusti Ayu Purnama Dewi Gusti Ayu Rusma Windiyana Putri HARI MULYAWAN Hegard Sukmawati, Ni Made Hendry Irawan I Gede Bagus Gita Pranata Putra I Gusti Ngurah Putu Sana I Ketut Labir I Ketut Labir I Ketut Suastika I Ketut Suwiyoga I Made Esa Sadana Yoga I Made Pariartha I Nengah Kapti I Nyoman Mangku Karmaya I Nyoman Sueta I W. Sudarsa I Wayan Darwata I Wayan Suwitra I Wayan Weta I.A.A. Widhiartini Ida Ayu Dewi Wiryanthini Kadek Dean Ariska Aryawangsa Kadek Yulita Dewi Lestari Komang Trisna Sumadewi Luh Gede Sri Yenny Luh Putu Kartika Darmapadmi Maheswari, Luh Putu Dewanda Ni Ketut Sutiari Ni Komang Surya Sanistiasih Budaya Ni Luh Putu Eka Kartika Sari Ni Luh Putu Suariyani Ni Made Dian Kurniasari Ni Made Vidya Pratiwi Ni Putu Sri Widhi Andayani Ni Putu Widarini Ni Wayan Septarini Ni Wayan Widhidewi Nyoman Triana Ayati Putu Ayu swandewi astuti Putu Dwiki Damadita Putu Sutisna Rina Listyowati Rina Listyowati, Rina Rini Hendari Rini Hendari, Rini Sagung Putri Permana Lestari MP Seshia Arma Dwi Permata Sri Juharni Sri Juharni, Sri Sri Trisnawati Sri Trisnawati Suryawisesa, Ida Bagus Made Viky Yudi Alvian Vivin Sumanti Vivin Sumanti Witari, Ni Putu Diah Yasa, I Nyoman Wawan Tirtha Yuliana Yuliana