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All Journal Jurnal Gizi dan Pangan The Indonesian Journal of Public Health Universa Medicina Paediatrica Indonesiana Journal of Medicine and Health Indonesian Journal of Obstetrics and Gynecology (Majalah Obstetri dan Ginekologi Indonesia) Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer) Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia World Nutrition Journal The New Ropanasuri Journal of Surgery Indonesian Journal of Global Health research JK Unila (Jurnal Kedokteran Universitas Lampung) The Indonesian Journal of Community and Occupational Medicine eJournal Kedokteran Indonesia The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Tirtayasa Medical Journal Occupational and Environmental Medicine Journal of Indonesia Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education and Research Institute Tirtayasa Medical Journal Journal of Medicine and Health
Indah S. Widyahening
Department Of Community Medicine, Faculty Of Medicine, Universitas Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Medicine & Pharmacology Neuroscience Nursing Public Health Other

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Occurrence of Covid-19 in Children Who Have Received Live-Attenuated Dengue Vaccination Rahma Karyanti, Mulya; Alam , Anggraini; Widyahening , Indah Suci; Hadinegoro, Sri Rezeki; Munasir , Zakiudin; Sasmono , R. Tedjo; Satari , Hindra Irawan
Proceedings Book of International Conference and Exhibition on The Indonesian Medical Education Research Institute Vol. 7 No. - (2023): Proceedings Book of International Conference and Exhibition on The Indonesian M
Publisher : Writing Center IMERI FMUI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69951/proceedingsbookoficeonimeri.v7i-.188

Abstract

Background: Possible cross-reactions/ false positives were reported in rapid dengue serology tests because antigenic similarities between SARS-CoV-2 and DENV. The study aims to evaluate the occurrence of COVID-19 in children who received chimeric-yellow fever tetravalent dengue vaccine. Methods: A case-control study was conducted in five districts primary healthcares in Jakarta aged 12 years and above through history of COVID-19 questionnaire. Clinical and laboratory confirmation were obtained, and blood draw was performed to measure neutralization RBD IgG SARS-CoV-2 antibody titer. The dengue vaccine group consists of subjects who have received CYD-TDV in 2011-2012 and are willing to participate. The non-dengue vaccine group were matched; all have not received dengue vaccine. Results: This study included 207 cases and 212 controls, with median age in cases 19 years (IQR 5) and control 15 years (IQR 4). Nineteen subjects in the dengue vaccine group have already been infected with COVID-19 before being given COVID-19 vaccine, compared to 11 subjects in the non-dengue vaccine group (P=0.131). The occurrence of COVID-19 in the dengue vaccine group was significantly higher (16 subjects) than the non-dengue vaccine group (4 subjects)(P=0.005) after COVID-19 vaccinations were given. Neutralization RBD IgG SARS-CoV-2 antibody titer was 71.96 U/ml (IQR 39.47) in the dengue vaccine group and 51.92 U/ml (IQR 49.03) in the non-dengue vaccine group(P=0.361). Conclusion: Our study showed that the occurrence of COVID-19 in the dengue vaccine group was higher than in the non-dengue vaccine group, which may suggest no cross reaction from dengue antibodies towards COVID-19, more studies are warranted.
Co-Authors Ade Mutiara Adi, Nuri Purwito Aji B Widodo Alam , Anggraini Ambar W Roestam Andon Hestiantoro Andrijono Andrijono Anggraini Alam, Anggraini Anis Karuniawati Anna nasriawati Annang Giri Moelyo Ano Rosdiana Aria Kekalih Arifianto, Angga Arnold Fernando Asmarinah Bambang Tridjaja AAP, Bambang Tridjaja Bernath Siagian Brodjonegoro, Sakti R Budi Wiweko Chandra, Dian Novita Danarto, Raden Deandra, Fadhila I. Denta Aditya Episana Dewi Friska Dewi S. Soemarko Dewi Sumaryani Soemarko Dewi Wulandari Dewi Yunia Fitriani Dicky Mahardhika Dina Tri Amalia Eri Widianto Faraji, Mahsa Fauzia, Khalida Fedri Rinawan, Fedri Fuk, Liem Jen Gayatri, Anggi Gita Pratama Guntur Darmawan Handaya, Adeodatus Y. Hariwibowo, Rinto Hartanto Bayuaji Hendri, Ahmad Z Herman Mulijadi Hindra I. Satari Indrawarman Soeroharjo Indriastuti Soetomo Irwan Suhadi Isbaniah, Fathiyah Iswanto, J. Judhiastuty Februhartanty KASMARA, E. Klara Sinabutar Kokok, Andwi Setiawan Kresna, Andreas Leopando, Zorayda E. Levina Chandra Khoe Luh Ade Ari Wiradnyani Luh Ade Wiradnyani, Luh Ade Marcellus Simadibrata K Mardiastuti Mardiastuti Mokoagow, M. Ikhsan Muchammad Arief Gunawan Muhammad A Aufa Muhammad F Alhas Muhammad Ilyas Mulya Rahma Karyanti, Mulya Rahma Munasir, Zakiudin Murdana, Nyoman Mustikaningrum, Arif Hening Nasution, Safruddin Neni Nurainy Nina Mariana Nur Rasyid Nuri Purwito Adi Pahlavie, Bonnie Medana Parmitasari, Parmitasari Ponco Birowo Prahara Yuri Pritta Ameilia Iffanolida Purwantyastuti Ascobat Raden I. Ismail Raden Muharam Natadisastra Rakhmi Savitri Hoesein Retno Wibawanti Revata Utama Rimonta F Gunanegara Rimonta F Gunanegara, Rimonta F Rini Mulia Sari Riyan Hari Kurniawan SANTOSO, S. S.I. Sasmono , R. Tedjo Sasmono, R. Tedjo Saunar, Rofy S. Setiawati, Elsa P. Siti Darifah Sofyan, Marwan Sri Rezeki Hadinegoro, Sri Rezeki Sudadi Hirawan SUMAPRAJA, K. Tanoto, Rodri Tirza Z Tamin Toar J.M. Lalisang Tony Loho Trinovita Andraini Usman, Nurhayat Vivi Setiawaty Wangsa, Andrean Wibowo, Suryo Yefta Moenadjat