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All Journal JURNAL KIMIA SAINS DAN APLIKASI Jurnal Penelitian Kesehatan Suara Forikes Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun Majalah Kedokteran Andalas Indonesian Journal of Global Health research Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Riset Ilmiah Jurnal Sains, Teknologi dan Kesehatan
Adrial Adrial
Andalas University
Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Potential of Bioactive Compounds from Gambier (Uncaria Gambir Roxb.) in Modulating Cognitive Function: A Scoping Review Rahmi Novita Yusuf; Adrial Adrial; Desmawati Desmawati; Nur Indrawaty Lipoeto
Indonesian Journal of Global Health Research Vol 7 No 4 (2025): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v7i4.5936

Abstract

Aging is a process of diminishing tissue capacity for self-repair and maintenance of normal structure and function, leading to vulnerability to injury and damage. The high incidence of neurodegenerative diseases coincides with increased life expectancy in the elderly. An unavoidable negative effect of neurodegenerative diseases is the potential to cause cognitive decline. Gambier (Uncaria gambir Roxb.), containing 90% catechin, is a traditional plant with potential to enhance cognitive function. This scoping review aims to map existing research on the potential of bioactive compounds from gambier in modulating cognitive function, based on research articles in journals from the last 10 years in the PubMed, PMC, Google Scholar, and Google Scholar databases (2014-2024). The research was conducted by collecting research data from the last 10 years, totaling 12 articles. Among these, 4 articles met the inclusion criteria, focusing on the potential of bioactive compounds from gambier in modulating cognitive function. The article screening was conducted systematically using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) as 1 a guideline, followed by screening based on inclusion and exclusion criteria. This scoping review found potential for bioactive compounds from gambier in modulating cognitive function, as evidenced by increased Montreal Cognitive Assessment (MoCA) scores, decreased levels of Beta Amyloid (Aβ), Microtubule-Associated Protein Tau (MAPT), Malondialdehyde (MDA) levels, and increased Brain-Derived Neurotrophic Factor (BDNF). The potential of catechin, the primary bioactive compound in gambier, which possesses antioxidant, anti-inflammatory, and neuroprotective effects, yields beneficial results in enhancing cognitive function in the elderly.
PERAN SERTA KADER DALAM PENDETEKSIAN DAN PENCEGAHAN INFEKSI CACING USUS DI KELURAHAN KORONG GADANG, KECAMATAN KURANJI, PADANG Nora Harminarti; Nuzulia Irawati Hasmiwati; Adrial Adrial; Nurhayati Nurhayati; Selfi Renita Rusjdi; Eka Nofita; Yuniar Lestari; Rosfita Rasyid; Firdawati Firdawati; Ida Rahma Burhan; Abdiana Abdiana; Husna Yetti
Jurnal Hilirisasi IPTEKS Vol. 2 No. 4.a (2019)
Publisher : LPPM Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jhi.v2i4.a.305

Abstract

Penyakit kecacingan masih menjadi masalah kesehatan dengan prevalensi yang tinggi ditemukan terutama di negara-negara non industri (negara yang sedang berkembang), seperti Indonesia. Prevalensi dan intensitas tertinggi didapatkan di kalangan anak usia sekolah dasar. Anak-anak merupakan sumber daya manusia yang sangat penting untuk pembangunan bangsa Indonesia di masa yang akan datang. Kelurahan Korong Gadang sebagai pemenang desa Kelurahan Berprestasi Peringkat II dipilih untuk melihat masih ter dapatkah infeksi cacing usus pada anak dengan kriteria daerah seperti ini. Penelitian ini menggunakan metode cross sectional study terhadap semua kader yang berada di wilayah Kelurahan Korong Gadang berupa pengumpulan tinja anak usia sekolah dasar oleh kader, pemeriksaan cacing usus terhadap tinja yang dikumpulkan di bagian Laboratorium Parasitologi Fakultas Kedokteran Universitas andalas Padang. Hasil dari penelitian ini menunjukkan bahwa kader berperan aktif dalam program pengendalian infeksi cacing usus. Pemeriksaan semua tinja yang dikumpulkan adalah tidak ditemukan adanya cacing usus. Kesimpulan pengabdian ini berupa hasil penilaian terhadap peran dari kader dalam masalah pencegahan penyakit cacing usus adalah baik. Semua kader yang dipilih melakukan pengumpulan tinja dan melakukan proses pre analitik dengan baik.
PROFIL PASIEN KANKER YANG MENJALANI RADIOTERAPI DI RUMAH SAKIT UNIVERSITAS ANDALAS PADANG TAHUN 2019-2020PROFIL PASIEN KANKER YANG MENJALANI RADIOTERAPI DI RUMAH SAKIT UNIVERSITAS ANDALAS PADANGTAHUN 2019-2020 Muhammad Azzel Hanggara; Fathiya Juwita Hanum; Adrial Adrial
EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan Vol. 1 No. 4 (2024): EMPIRIS : Jurnal Sains, Teknologi dan Kesehatan, Desember 2024
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/z5hnab15

Abstract

Background: Cancer is a non-communicable disease, which is one of the causes of death. In the future, it is predicted that this cancer will continue to increase, especially in developing countries, including Indonesia. Methods: This study is a descriptive observational study with a retrospective approach. The sampling method in this study was total sampling with the number of samples in this study being 510 samples. The instrument used in this study is secondary data from medical records. The data obtained will be processed and presented in the form of distribution tables and graphs. Results: According to the findings of this study, the majority of cancer patients who received radiotherapy were between the ages of 45 and 54 (30.78%), and the female population was larger than the male population, at 72.5 percent versus 27.5 percent, respectively. %), the majority of patients came from the province of West Sumatra (80.5%), and the most common occupation was housewife (44.8%). Stage IV is the most common stage (26.1%), and the highest anatomical pathology result is invasive carcinoma of no special type (breast cancer) .Conclusion: Based on the results of this research, it can be concluded that the distribution of patients based on gender was more female than male. The distribution of patients based on domicile, who came from West Sumatra Province is the highest. Distribution in West Sumatra Province which consists of districts and cities, Padang City was the highest with a number of patients. The distribution of patients based on age shows that the most common age ranges for cancer patients are 45-54 years and 55-64 years. The distribution of cancer patients in terms of occupation, the majority are housewives (IRT) as many as 227 people (44.5%), civil servants, TNI Polri as many as 70 people (13.7%), private sector and self-employed as many as 61 people (12.0%).
Co-Authors Abdiana Abdiana, Abdiana Afriani, Nita Almurdi Almurdi Amatulqaiyum Idri Sari Ariadi Ariadi Aswiyanti Asri Desmawati Desmawati Dira Hefni Dwitya Elvira Dwitya Elvira, Dwitya Eka Nofita Endrinaldi Eryati Darwin Fathiya Juwita Hanum Febriyanti, Rizka Firdawati Firdawati Gardenia Akhyar Gian Primahana Gustia Anugrahwati Hanifah Putri Dwiridal Hasmiwati Hendriati, Hendriati Husna Yetti Husnil Wardiyah Ida Rahma Burhan Ilmiawati, Ilmiawati Jepri Agung Priyanto Linosefa Linosefa Miftah Ar Rahmah Muhammad Azzel Hanggara Muhammad Eka Prastya Muhammad Rafif Sulthan Habibi Nora Harminarti Nur Indrawaty Lipoeto Nurhayati Nurhayati Nurhayati, Nurhayati Nuzulia Irawati Nuzulia Irawati Hasmiwati Qaira Anum Rafifa Ridha Rahmi Novita Yusuf Rika Susanti Rosfita Rasyid Samantha Samantha Selfi Renita Rusjdi Selfi Renita Rusjdi Yenita Afriyeni Yulistini, Yulistini Yuniar Lestari Zetryana Puteri Tachrim