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PENGARUH KONSUMSI AIR SERAI (CYMBOPOGON CITRATU), JAHE (ZINGIBER OFFICINALE), JERUK NIPIS (CITRUS AURANTIIFOLIA) DAN MADU HANGAT DALAM MENGATASI HIPEREMESIS GRAVIDARUM PADA IBU HAMIL TRIMESTER I Pratiwi, Lusy; Ambarsari, Niati; Nuraeni, Ani
Jurnal Ilmiah Kesehatan Ar-Rum Salatiga Vol 9, No 1 (2024)
Publisher : STIKES Ar-Rum Salatiga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36409/jika.v9i1.252

Abstract

Pada paruh pertama hingga tiga perempat masa kehamilan, mual dan muntah dialami oleh sekitar lima puluh persen hingga tujuh puluh lima persen wanita Indonesia, menurut statistik dari Kementerian Kesehatan. Terdapat metode farmakologis dan nonfarmakologis untuk menurunkan hiperemesis . Infus jahe, madu, serai, dan jeruk nipis merupakan salah satu jenis pengobatan herbal yang tidak mengandung bahan farmasi. Penelitian ini menggunakan one-group pretest-posttest design untuk penelitian pendahuluannya. Hiperemesis gravidarum dialami oleh 25 wanita hamil trimester pertama yang menjadi subjek penelitian ini. Metode pengambilan sampel menggunakan strategi pengambilan sampel yang komprehensif. Sebelum dan sesudah diberikan seduhan air serai, jeruk nipis, jahe, dan madu, partisipan akan mengisi kuesioner observasi pada lembar instrumen PUQE-24. Data akan dianalisis menggunakan metode univariat dan bivariat. Nilai p sebesar 0,000 menunjukkan bahwa terdapat hubungan yang signifikan secara statistik antara hiperemesis gravidarum dengan trimester pertama kehamilan dan konsumsi infus serai, jeruk nipis, jahe, dan madu oleh ibu hamil. Karena nilai p kurang dari 0,05, maka dapat disimpulkan bahwa H0 ditolak dan Ha diterima. Kesimpulan, ibu hamil trimester pertama dapat terbebas dari hiperemesis gravidarum setelah minum campuran jahe, serai, jeruk nipis, dan madu.
Isolasi dan Identifikasi Senyawa dari Ekstrak Etanol Daun Mareme (Glochidion arborescens Blume.) Haryoto, H; Ambarsari, Niati
Prosiding University Research Colloquium Proceeding of The 16th University Research Colloquium 2022: Bidang MIPA dan Kesehatan
Publisher : Konsorsium Lembaga Penelitian dan Pengabdian kepada Masyarakat Perguruan Tinggi Muhammadiyah 'Aisyiyah (PTMA) Koordinator Wilayah Jawa Tengah - DIY

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Abstract

Mareme (Glochidion arborescens Blume.) is one of wild plants growing in yard. The leaves are able to be used as traditional medicine since it is considered containing secondary metabolites, such as flavonoids, phenols, alkaloids, saponins, tannins, steroids, triterpenoids, as well quinones. FT-IR (Fourier Transform Infrared Spectroscopy) is used to identify the functional groups in a sample and secondary metabolites of medicinal plants. The objective of study was to identify Mareme leaves (Glochidion arborescens Blume.) isolate seen from functional group. Mareme (Glochidion arborescens Blume.) leaves powder was extracted using maceration method, and then thick extract was fractionated using Vacuum Liquid Chromatography (VLC) and isolated using a chromatotron. FT-IR was used to identify Mareme leaves isolate. Mareme leaves (Glochidion arborescens Blume.) thick extract obtained was 95,52 grams, non-polar fraction was 3,75 grams, semi-polar fraction was 3,90 grams, polar fraction was 3,25 grams, as well isolate was 850 mg. The analysis results by using FT-IR indicate that -OH, -CH aliphatic, -C=O ester and -C-O, active isolates of Mareme leaves (Glochidion arborescens Blume.) are suspected of containing flavonoid compound of flavone group.
Liquid Soap Formulation Ethanol Extract Avocado Skin (Persea americana) Against Bacteria Staphylococcus aureus Suryani, Ade Irma; Ambarsari, Niati; Oktaviani, Milla; Rerung, Lola’ Tulak; Sari, Rahayu Mustika; Kemal, Amir; Dewi, Hasna
ENDLESS: INTERNATIONAL JOURNAL OF FUTURE STUDIES Vol. 6 No. 1 (2023): ENDLESS : International Journal of Future Studies
Publisher : Global Writing Academica Researching & Publishing

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Abstract

Avocado peels contain Flavonoid compounds and alkaloids as antibacterial. In this study, the ethanol extract of Avocado peels was formulated as a liquid soap using concentrations of FI (1%), FII (3%) and FIII (5%). This study aimed to formulate a liquid soap from a sample of Avocado peel extract against the antibacterial activity ofStaphylococcus aureususing the agar diffusion method in wells. Physical evaluation of liquid soap preparations includes several parameters, namely organoleptic tests including odour, shape and colour, pH test, foam stability test, viscosity test and homogeneity test. The results obtained from testing liquid soap using ethanol extract of Avocado peels with varying concentrations of 1%, 3% and 5% can inhibit the growth of Staphylococcus aureus bacteria, namely 1% = 19.6, 3% = 21.6 and 5% = 25.8. Based on the results of this study it can be concluded that the ethanol extract of Avocado peels (Persea americana) can be formulated in the form of liquid soap and is effective against inhibition of Staphylococcus aureus bacteria. In this study, FIII fulfilled the physical quality evaluation test and had activity as an antibacterial, with the resulting inhibition zone at a concentration of 5% = 26.6 mm, a powerful category.
ANALISA DRUG RELATED PROBLEM PADA ENDOMETRIOSIS DI PUSKESMAS DUREN SERIBU PERIODE 1 JANUARI - 30 JUNI 2025 Mustika Sari, Rahayu; Ambarsari, Niati
Journal of Pharmacy Tiara Bunda Vol. 5 No. 2 (2025): Journal of Pharmacy Tiara Bunda (JPTB)
Publisher : Politeknik Tiara Bunda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62619/jptb.v5i2.276

Abstract

This study analyzed the incidence of drug-related problems, including adverse events and medical errors, and possible associated risk factors, in patients with endometriosis who used combined oral contraceptives (COCs) and progestins. Reports were collected between January 1, 2024, and June 30, 2025, regarding endometriosis patients in the Medical Record System at the Duren Seribu Community Health Center, Depok City. A disproportionate analysis was performed using the Gamma–Poisson Shrinker model to detect overreported drug–event pairs. Logistic regression analysis was used to explore potential risk factors. There were 23 reports regarding long-term hormonal treatment and 45 reports regarding other medications used for endometriosis. Long-term hormonal treatment included: 15 reports (22.0%) of combined oral contraceptives (COCs), 10 reports (14.7%) of oral progestins, 8 reports (11.76%) of injectable (depot) progestins, 23 reports (33.82%) of progestin-releasing IUDs, and 12 reports (17.64%) of progestin-only implants. Both combined oral contraceptives (COCs) and progestin-only products are relatively safe for patients with endometriosis. Combination therapy (polytherapy) has been negatively associated with several medical errors in COC users, while patients aged ≥30 years have had more pulmonary embolism cases but fewer reported product-related problems.
Analisis Waktu Tunggu Pelayanan Resep Racikan dan Non Racikan di Apotek X Cilandak Niati Ambarsari; Lola’ Tulak Rerung; Adnes Monica
Journal of Innovative and Creativity Vol. 5 No. 3 (2025)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v5i3.3329

Abstract

Waktu tunggu pelayanan resep merupakan salah satu hal untuk meningkatkan mutu pelayanan kesehatan masyarakat. Waktu tunggu pelayanan resep dibagi menjadi dua yaitu waktu tunggu pelayanan resep obat non racikan dan waktu tunggu pelayanan resep obat racikan. Di Indonesia, standar waktu tunggu yang ditentukan dalam Permenkes melalui Standar Pelayanan minimal yaitu, pelayanan resep obat non racikan adalah < 30 menit dan obat racikan adalah < 60 menit. Tujuan dari penelitian ini adalah untuk mengenai analisis waktu tunggu pelayanan resep racikan dan non racikan di Apotek X Cilandak. Metode pengambilan sampel yang digunakan adalah resep dialmbil menggunakan teknik accidental sampling dengan populasi yang diambil dari rata-rata 3 bulan terakhir yakni bulan Maret – Mei 2024 dan didapatkan 5.600 resep. Dari hasil penelitian didapat rata-rata waktu tunggu pelayanan resep di Apotek X Cilandak untuk obat racikan 32,8 menit sedangkan untuk obat non racikan adalah 14,1 menit. Dapat disimpulkan bawah waktu tunggu pelayanan resep obat racikan dan obat non racikan di Apotek X Cilandak sudah memenuhi Standar Pelayanan Kefarmasian di Apotek sesuai standar waktu tunggu yang ditentukan dalam Permenkes.
ANALYSIS OF THE IMPLEMENTATION OF MEDICINE STORAGE SYSTEMS IN PHARMACIES Ahmad Subagiyo; Niati Ambarsari, Milla Oktaviani
INTERNATIONAL JOURNAL OF SOCIETY REVIEWS Vol. 2 No. 4 (2025): INTERNATIONAL JOURNAL OF SOCIETY REVIEWS (INJOSER)
Publisher : Adisam Publisher

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Abstract

The pharmacy is one of the places and dedication of the pharmacist profession to carry out pharmaceutical work. Storage of medicines in pharmacies is an inseparable part of medicine management activities. The activity of storing and maintaining the medicines received in a safe place to maintain the quality of the medicines and from theft is medicine storage. One of the determining factors for the quality of distributed medicines is a good and appropriate medicine storage system. Drug storage is an inseparable part of all pharmaceutical activities, both hospital pharmacy and community pharmacy. The act of keeping received medications in a location that is both secure against theft and capable of preserving their quality is known as medicine storage. An appropriate and good storage system will be one of the determining factors for the quality of medicines distributed. Implementing a medicine storage system in pharmacies is very crucial to ensure that medicines are stored safely, efficiently and in accordance with regulatory standards. Implementing a good medicine storage system not only helps in maintaining the quality and effectiveness of medicines, but also increases the operational efficiency of pharmacies and ensures patient safety.
Evaluasi Pola Peresepan Obat Antihipertensi Pada Pasien Rawat Jalan Di UPTD Puskesmas Cinere-Depok Periode Oktober Sampai Desember 2024 La Malihi; Lusy Pratiwi; Niati Ambarsari; Etik Yuliayana
Journal of Innovative and Creativity (Joecy) Vol. 6 No. 2 (2026)
Publisher : Fakultas Ilmu Pendidikan Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/joecy.v6i2.13571

Abstract

Latar Belakang: Hipertensi merupakan penyakit kardiovaskular kronis yang sering dialami pasien geriatri akibat penurunan fungsi organ. Tingginya risiko kesalahan peresepan pada kelompok ini mendorong diperlukannya evaluasi pola peresepan obat antihipertensi di UPTD Puskesmas Cinere guna mencegah terapi irasional dan meningkatkan kualitas hidup pasien. Tujuan: Menganalisis pola peresepan obat antihipertensi pada pasien geriatri di UPTD Puskesmas Cinere berdasarkan komparasi literatur primer dan sekunder. Metode: Penelitian deskriptif retrospektif ini dengan menelaah 788 resep fisik pasien geriatri rawat jalan pengguna antihipertensi periode 1 Oktober–31 Desember 2024. Data karakteristik pasien (usia, jenis kelamin, diagnosis, status pembayaran) dan pola obat dianalisis secara persentase serta dibandingkan dengan standar literatur rasionalitas obat. Hasil: Mayoritas pasien adalah perempuan (70,68%), berusia 60–70 tahun (75,63%), dan menggunakan BPJS (91,37%). Antihipertensi monoterapi yang paling banyak diresepkan adalah Amlodipin/CCB (92,85%), sedangkan kombinasi terbanyak adalah Amlodipin + Captopril (CCB + ACE-I). Seluruh obat diberikan secara oral.Kesimpulan: Pola peresepan antihipertensi baik dosis tunggal maupun dosis kombinasi pada pasien geriatri di UPTD Puskesmas Cinere sudah sesuai dengan literatur panduan. Terapi ini dinilai efektif menurunkan tekanan darah, meningkatkan kualitas hidup, serta meminimalkan risiko jatuh dan stres pada pasien.