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Comparison of anti-SARS-CoV-2 IgG seropositivity among vaccinated, unvaccinated, and COVID-19 survivor individuals: A cross-sectional study in Palembang, Indonesia Retnaningsih, Ekowati; Nuryanto, Nuryanto; Oktarina, Reni; Komalasari, Oom; Maryani, Sri; Larasti, Veny; Fertilita, Soilia
Narra J Vol. 5 No. 3 (2025): December 2025
Publisher : Narra Sains Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52225/narra.v5i3.2890

Abstract

Measurement of anti–severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) immunoglobulin G (IgG) antibody levels provides evidence of prior infection or vaccination. Persistent vaccine hesitancy underscores the importance of robust, evidence-based data to inform policy decisions. The aim of this study was to compare anti-SARS-CoV-2 IgG seropositivity among vaccinated individuals, unvaccinated individuals, and coronavirus disease 2019 (COVID-19) survivors in the community during the pandemic. In this cross-sectional study, 517 participants were enrolled, including 167 vaccinated individuals, 97 COVID-19 survivors, and 253 unvaccinated individuals, selected through multistage cluster sampling of 40 clusters. Anti-SARS-CoV-2 IgG seropositivity was defined as ≥50 AU/mL. Multivariable logistic regression was performed to evaluate associations between group type and seropositivity, adjusting for demographic factors, COVID-19 symptoms, hypertension, and body mass index (BMI). Vaccinated individuals demonstrated significantly higher odds of seropositivity compared with unvaccinated participants (odds ratio (OR)=5.60; 95% confidence interval (CI): 2.36–13.27). Covariates independently associated with seropositivity (p<0.05) included the presence of COVID-19 symptoms, hypertension, and BMI. Vaccination was strongly associated with increased anti-SARS-CoV-2 IgG seropositivity in the community, independent of clinical and demographic factors. These findings support ongoing vaccination campaigns and highlight the relevance of comorbidities and symptomatic history in shaping humoral immune responses.
Parent-adolescent communication and adolescent mental health outcomes: A systematic review Saraswati, Dewa Ayu Sri; Mujahidah, Zakiyah; Komalasari, Oom
Lentera Perawat Vol. 7 No. 2 (2026): April - June
Publisher : School of Health Sciences Al-Ma'arif

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52235/lp.v7i2.767

Abstract

Background: Parent-adolescent communication is an essential family process that may influence adolescent mental health outcomes, particularly during a developmental period marked by emotional, social, and behavioral transitions. Poor communication within the family may increase adolescents’ vulnerability to depression, anxiety, emotional difficulties, behavioral problems, suicidal ideation, and low psychological well-being. Objective: This systematic review aimed to synthesize current evidence on the relationship between parent-adolescent communication and adolescent mental health outcomes. Methods: This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 guideline. Literature searches were conducted in Scopus, ProQuest, PubMed, and SAGE Journals, with the final search completed in March 2026. Eligible studies were primary empirical articles published between 2015 and 2026 in English or Indonesian, involving adolescents aged 10–19 years or samples predominantly composed of adolescents. Study selection, quality appraisal, and data extraction were conducted independently by two reviewers, with disagreements resolved through discussion or consultation with a third reviewer. The Joanna Briggs Institute Critical Appraisal Checklists were used to assess methodological quality. A narrative synthesis was performed because of heterogeneity in study designs, populations, communication measures, and mental health outcomes. Results: Of 10,803 records initially identified, 10 studies were included in the final synthesis. The evidence showed that positive, open, consistent, and culturally sensitive parent-adolescent communication was associated with better adolescent mental health outcomes. Poor communication was linked to higher depressive symptoms, anxiety, emotional distress, behavioral problems, family conflict, and reduced treatment engagement. Communication also supported emotional disclosure, help-seeking behavior, parental care management during suicidal crises, and engagement in family-centered mental health interventions. Cultural context, digital exposure, parental mental health literacy, and structural barriers influenced the quality of communication. Conclusion: Parent-adolescent communication is a key protective factor for adolescent mental health. Family-centered prevention and clinical interventions should strengthen parental listening, emotional validation, mental health literacy, crisis response, and culturally responsive communication.