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The Effectiveness of Topical Tea Tree Oil (Terpinen-4-Ol) in Human Demodicosis: A Literature Review Ayu Mayangsari; Ratih Pramuningtyas; Aulia Nissa Rizky Hariyono; Zhela Fatin Fatiha; Tia Mella Citra
Budapest International Research and Critics Institute (BIRCI-Journal): Humanities and Social Sciences Vol 4, No 3 (2021): Budapest International Research and Critics Institute August
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v4i3.2312

Abstract

Demodecosis is a skin disorder caused by parasites with the demodicosis type. The primary cause of this condition in humans is two kinds of Demodex mites, D.folliculorum and D.brevis. Demodicosis are usually treated with TTO, but the effectiveness is not well documented. To evaluate the effects of topical Tea Tree Oil on demodicosis infestation in people. We use the following string in Google Scholar; PubMed; Science Directs with keywords (“Demodicosis”iORi“demodex”iOR"D.folliculorum"iORii"D.Brevis) ANDi (TTOiORiT4OiOR "tea tree oil"). The articles compatible with the restriction criteria then screened using the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) method.  The quality of the articles is tested using GRADE method. A total of 4 of 1949 articles recorded according to the inclusion criteria, all three articles were randomized clinical trials. 351 patients were treated with topical Tea Tree Oil (TTO) scrub with eyelash shampoo, the most common ocular symtomps is ocular dryness. The treatment is provided on a scale 18 to 35 years of age, topical TTO scrub with consentrated persentation 5-50% with eyelash shampoo was at twice-daily treament for 4 weeks. No serious side effect. Topical administration of Tea Tree Oil has shown a reduction in human demodicosis.
Propranolol Oral Treatment for Infantile Hemangioma : A Systematic Review Aulia Nissa Rizky Hariyono; Ratih Pramuningtyas; Zhela Fatin Fatiha; Ayu Mayangsari; Tia Mella Citra
Budapest International Research and Critics Institute (BIRCI-Journal): Humanities and Social Sciences Vol 4, No 3 (2021): Budapest International Research and Critics Institute August
Publisher : Budapest International Research and Critics University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33258/birci.v4i3.2308

Abstract

The most common benign tumor in infants is infantile hemangioma. Propranolol is often used as a treatment in patients with IHs. Efficacy and side effects of oral propranolol are considered important to be systematically reviewed in the management of IH. We searched Google Scholar, Pubmed, Garuda, and Science Direct. The articles matched with the restriction criteria then screened using the PRISMA method. The quality of the articles is tested using GRADE method. Total of 4 of 6289 articles recorded at the identification stage according to the inclusion criteria, 452 patients were treated with oral propranolol. All four articles were randomized clinical trials. Treatment is given at 0.3 month to 15 years of age, the dose given is 1-3 mg/kg/day. The primary end point was performed at week 24. The most common side effect is sleeping disorder (n=85). Serious side effects (Hypotension, bronchospasm, bradycardia, hypoglycemia) were managed by decreasing doses or temporary/permanent discontinuation of oral propranolol. Oral propranolol can be used with good efficacy. Monitor before and during treatment is assessed appropriately to reduce side effect.
Co-Authors Anggelina Aiyoslla Nabilla Putu Pratomo Annisa, Valda Yulia Anshar, Rizadin Aulia Nissa Rizky Hariyono Aulia Nissa Rizky Hariyono Awanis, Ghina Shabrina Ayu Mayangsari Ayu Mayangsari Aziz, Yusuf Abdullah Budi Rahmawati Burhannudin Ichsan Dahlia Winda Nurarifah Delima Anggraini Hudini Devi Usdiana Rosyidah Dianisa Indira Putri Dibintang Akbari, Cut Aqsa Dimawan, Rully Setia Agus Dodik Nursanto Dzikri, Dykall Naf'an Dzikri, Dykall Naf’an Em Sutrisna Erika Diana Risanti Erna Herawati Faradisa, Nida Febriani Aldila Safitri Fithriyah, Saidatul Flora Ramona Prakoeswa Flora Ramona Sigit Prakoeswa Flora Ramona Sigit Prakoeswa Harun Joko Prayitno Hindun Luthfia Rosyida Hudini, Delima Anggraini Islamuddin, Tri Kurnia Ahmad Izzati, Ismatu Aghni Fatwa Kencana, Nabila Safhira Titan Kurniasih, Rahmi Laksono Trisnantoro Listiana Masyita Dewi Lulu Setyawati Purwaningsih Metana Puspitasari Mibawani, Aliza Moh. Shoim Dasuki Nafasadila, Fatma Nafila, Alfin Niken Sari Oktafiani Niken Sari Oktafiani Nining Lestari Nur Alfi Khoirul Fajriati Nurhayani nurhayani Nurwina, Hasna Syifa Pranesti, Rahma Prasetyadi Mawardi Prasetyadi Mawardi Putri, Elsya Nur Fadhilla Raharja, Supanji Rahmi Kurniasih Retno Sintowati Rizadin Anshar Rochmadina Suci Bestari Rully Setia Agus Dimawan Safitri, Febriani Aldila Saiful Hidayat Sari, Winda Atika Sherin Jeanica Tresya Siti Soekiswati Supanji Raharja Tia Mella Citra Tia Mella Citra Tri Agustina Valda Yulia Annisa Yuni Prastyo Kurniati Yusuf Alam Romadhon Zhela Fatin Fatiha Zhela Fatin Fatiha