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All Journal PHARMACON Jurnal Mahasiswa Farmasi Fakultas Kedokteran dan Ilmu Kesehatan UNTAN Jurnal Teknosains Interest : Jurnal Ilmu Kesehatan Biology, Medicine, & Natural Product Chemistry Majalah Obat Tradisional JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA As-syifaa Jurnal Farmasi JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) JURNAL PENGABDI Media Farmasi Al-Khidmah PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat Journal Syifa Sciences and Clinical Research (JSSCR) Jurnal Riset Kefarmasian Indonesia Media Farmasi Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Sains dan Kesehatan Journal Pharmacy of Tanjungpura
Isnindar Isnindar
Bagian Biologi Farmasi Fakultas Kedokteran Universitas Tanjungpura Pontianak
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Civil Engineering, Building, Construction & Architecture Control & Systems Engineering Economics, Econometrics & Finance Education Energy Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Law, Crime, Criminology & Criminal Justice Mechanical Engineering Medicine & Pharmacology Nursing Public Health Social Sciences Other

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Antioxidant Activity of n-Hexane Subfraction of Buas-Buas Leaf (Premna serratifolia L.) by DPPH Method Darin Iftinan; Isnindar Isnindar; Sri Luliana
Biology, Medicine, & Natural Product Chemistry Vol 15, No 1 (2026)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2026.151.569-573

Abstract

Buas-buas (Premna serratifolia L.) is a plant traditionally used as medicine and widely grown in West Kalimantan with various species. There are many benefits of buas-buas plants as medicine, one of which is as an antioxidant. The purpose of this study was to determine the percent inhibition value that describes the antioxidant activity of ethanol extract, n-hexane fraction, and n-hexane subfraction of buas-buas leaves. The n-hexane fraction was obtained by liquid-liquid extraction with separatory funnel from ethanol extract and the fraction was isolated by column chromatography. The antioxidant activity of the ethanol extract, n-hexane fraction, and subfractions C1, C2, C3, D123, and E3F123 was assessed using DPPH (2,2-Diphenyl-1-Picrylhydrazyl). The results showed that ethanol extract, n-hexane fraction, and subfractions C1, C2, C3, D123, and E3F123, had antioxidant activity with percent inhibition values of 57.946; 53.078; 52.652; 48.706; 49.745; 50.490; and 50.639%, respectively, which indicated that each sample had good antioxidant activity, except for subfractions C2 and C3.
Patterns of Antihypertensive Drug Prescribing and Refill Adherence Among BPJS Referral-Back Patients: A Study at Pharmacy “X”, Pontianak Isnindar Isnindar; Shahiroh Haulaini Shahiroh Haulaini; Hestiva Hestiva; Berlian Rizky Putra
Jurnal Riset Kefarmasian Indonesia Vol. 8 No. 1 (2026): Jurnal Riset Kefarmasian Indonesia
Publisher : APDFI (Asosiasi Pendidikan Diploma Farmasi Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33759/jrki.v8i1.902

Abstract

High blood pressure often develops without obvious symptoms, causing many individuals to remain unaware of the condition until organ damage has already occurred. The absence of noticeable signs makes hypertension a major contributor to the increasing incidence of complications within the cardiovascular system. It has become a government priority to control hypertension through the National Health Insurance Program (JKN) BPJS, particularly the Referral Back Program (Program Rujuk Balik/PRB). This study aims to describe medication refill adherence and prescribing patterns of antihypertensive drugs among BPJS Kesehatan participants at “X” Pharmacy, Pontianak. This research employed a descriptive observational design with retrospective data from prescriptions and the Pharmacy–BPJS application for the period of October 2025. The analyzed data included sex, age, and the types of antihypertensive therapy used. Adherence was asessed using the Medication Possession Ratio (MPR) method. The results showed that medication refill adherence among PRB patients at Pharmacy “X” was predominantly in the adherent category. The most frequently prescribed antihypertensive drug was candesartan, an angiotensin receptor blocker (ARB), with a tendency toward combination therapy. Most patients were within the 60–75 age group and were predominantly female. In conclusion, medication refill adherence among PRB antihypertensive patients was generally good, supporting long-term therapeutic effectiveness. The prescribing patterns observed were largely consistent with clinical practice guidelines for hypertension management. Continuous education and monitoring are recommended to further improve adherence and therapeutic outcomes.  
Co-Authors Adahane, Euistya Febrianti Putri Amaria, Egita Feby Ananda, Elcie Anastasia, Desy Siska Azizzah Dwi Rahmawati Azura, Dhea Nur Badaria, Lailatul Bambang WIJIANTO Berlian Rizky Putra Cristin, Bella Darin Iftinan Dina Pratiwi, Dina Erna Prawita Setyowati Erna Prawita Setyowati Erna Prawita Setyowati Hadi Kurniawan, Hadi Hariyanto IH Hervianto, Willy Hestiva Hestiva Ilham Saputra Kamil, Insan Liza Pratiwi Luliana , Sri Luliana, Sri Maulidia, Yuninta Nadine, Shahira Audia Nasution, Nuraini Nur Atikah Purnamaputra, Alfred Putri, Dinda Marlinda Rafika Sari Rahmi Septiani Ricky Midi Candra Rise Desnita, Rise Rissa Febriyanto Robiyanto Robiyanto, Robiyanto Robiyanto, Robiyanto Ropiqa, Meri Saputra, Ilham Shahiroh Haulaini Shahiroh Haulaini Sitarina Widyarini Sitarina Widyarini Siti Nani Nurbaeti Sri Wahdaningsih Subagus Wahyuono Subagus Wahyuono Subagus Wahyuono Subagus Wahyuono Syalsabila, Regitha Rianda Tara Kamita Riduana Tarung, Albianus Febri Uray Cindy Hafinur Willy Hervianto Wintari Taurina Yuswanto Yuswanto Yuswanto Yuswanto Yuswar, Muhammad Akib Zahid, Muhammad