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IDENTIFICATION OF METABOLITE COMPOUNDS IN EXTRACT AND EXTRACT FRACTIONS OF MORINGA LEAVES (Moringa oleifera) USING THIN LAYER CHROMATOGRAPHY (TLC) METHOD Khairi, Widayatul; Safwan; Hendriyani, Irmatika
Jurnal Biosains Pascasarjana Vol. 27 No. 2 (2025): JURNAL BIOSAINS PASCASARJANA
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jbp.v27i2.2025.175-182

Abstract

Moringa oleifera, known in Indonesia as "kelor," is often referred to as "the miracle tree" due to its natural nutritional and medicinal properties. Compounds found in Moringa leaf extract have been confirmed to include flavonoids. These compounds contain -OH groups attached to benzene rings, which contribute to their antioxidant, anti-inflammatory, and antimicrobial properties. The aim of this study was to identify secondary metabolites in Moringa leaves using the Thin Layer Chromatography (TLC) method. The results showed that flavonoids, tannins, alkaloids, and saponins were present in the ethyl acetate fraction, while tannins were found in both the extract and aqueous fraction. Additionally, steroids were detected in the n-hexane fraction. In conclusion, Moringa oleifera contains secondary metabolite compounds.
ANTIDIABETES DAN PROFIL HISTOPATOLOGI SEL BETA PANKREAS PADA MENCIT MODEL INDUKSI STREPTOZOTOSIN EKSTRAK ETANOL DAUN RENGGAK (Amomum dealbatum L.) Mislamah; Mislamah, Mislamah; Amalia, Ananda Ayu Amalia; Firma, Firma Amelia Kusuma; Abdul, Abdul Rahman Wahid; Safwan
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 10 No 2 (2025): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v10i2.2131

Abstract

antidiabetic effects because their flavonoid levels are higher than the fruit. This study aims to determine the antidiabetic activity of ethanol extract of renggak leaves (EEDR), the optimal dose and the histopathological profile of the mouse pankreas. To determine its antidiabetic activity, a pre-test (initial blood sugar level before STZ induction) and post-test (after STZ induction) were carried out on the blood sugar levels of mice. A total of 36 male white mice were divided into 6 groups, namely normal group, negative group (Na-CMC 0.5%), positive group (Metformin 500 mg), EEDR group at doses of 240, 300, and 360 mg/kgBW.. Test results LSD posthoc showed that there was a mean difference between treatment groups with significant antidiabetic activity (p value <0.05). The ethanol extract group of renggak leaves was dosed at 240 mg/kgBW. The histopathological profile of the pankreas in each group showed extensive necrosis, the islets of Langerhans and inch tubules were difficult to distinguish, the cells looked degenerative with incomplete cytoplasm and degenerative nuclei.
Community Behavior Regarding Waste Management in Slums (Case Study: Lamglumpang, Ulee Kareng, Banda Aceh) Maisari, Lia; Fuady, Mirza; Safwan
International Journal of Architecture and Urbanism Vol. 9 No. 3 (2025): International Journal of Architecture and Urbanism
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/ijau.v9i3.23585

Abstract

In Banda Aceh, garbage is a significant concern. The trash problem requires the participation of the community. However, there are still numerous litterers, such as in the Gampong Lamglumpang, Ulee Kareng district. Gampong Lamglumpang is one of the villages identified as slums in Banda Aceh City. Poor waste management is a contributing factor to the slums. This study intends to assess the community's waste management practices in Gampong Lamglumpang and propose solutions to these issues. The study uses a descriptive quantitative by employing a questionnaire to collect data, which would be analyzed using Microsoft Excel. The data collection used the purposive sampling method. The sampling was up to sixty families. According to findings, many families were still burning their waste, indicating that their waste management was still insufficient. The author's suggestion for the government is to play a role in changing people's behaviour, such as by giving education and socialization of the 3Rs (reuse, reduce, and recycle) and by teaching the community how to transform garbage into something of economic worth. In addition, the Government must optimize waste transportation for must be optimized for the preservation of a clean environment.
Ekonomi Islam Studi Pemikiran Paul Karl Feyerabend tentang Anarkhi Epistemologis Khanifa, Nurma Khusna; Mutmainah, Kurniawati; Safwan
TRIPUTRA : Sosial, Ekonomi dan Hukum Vol. 1 No. 02 (2024): Mei
Publisher : CV Nature Creative Innovation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58641/triputra.v1i02.92

Abstract

Filsafat ilmu memberikan perspektif tentang apa dan bagaimana metodologi ekonomi sepatutnya dikembangkan. Metodologi ekonomi sebenarnya adalah “filsafat ilmu yang diaplikasikan dalam ilmu ekonomi” sebagai “pemikiran alternative” yang ditawarkan oleh Feyerabend. Metode yang digunakan pada penelitian ini adalah kualitatif berupa analisis isi (content analysis) terhadap anarkhi epistemologis Paul Karl Feyerabend dan relevansinya pada epistemologi ekonomi Islam. Berdasarkan tempat pelaksanaan, penelitian ini adalah penelitian pustaka (library research). Berdasarkan taraf pencapaian, penelitian ini adalah penelitian deskriptif (descriptive research). Nantinya data yang terkumpul ditelaah dianalisis secara mendalam. Hasil kajian menunjukkan bahwa Epistemology Islam mengakui peran wahyu Tuhan (al-wahy) sebagai sumber ilmu pengetahuan, disamping fakta empirical dan akumulasi pengalaman manusia (facts observations) serta penalaran akal (intellectual reasoning). Pendekatan ekonomi Islam diantaranya all or nothing approach, pendekatan Islamization of economics, pedekatan utopian approach dan pendekatan pragmatist approach. Maka terdapat tiga tipologi pendekatan dan metodologi ekonomi Islam yaitu: metodologi fikih (usūl al-fiqh), metodologi pluralisme, dan metodologi Islamisasi ilmu pengetahuan. Ekonomi Islam, sebaliknya, adalah sebuah doktrin yang memainkan peranan “untuk menyingkap visi keseluruhan Islam dalam bidang ekonomi berdasarkan syari’ah dan mempelajari konsep (ide) yang muncul dari visi Islam. Tujuannya adalah melahirkan manusia ekonomi Islam (homo Islamicus) yang sadar akan nilai-nilai Islam dalam perilaku ekonomi