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I Wayan Bikin Suryawan
Bagian/SMF Ilmu Kesehatan Anak Fakultas Kedokteran Universitas Udayana/RSUP Sanglah, Denpasar
Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary

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Journal : Pediatric Sciences Journal

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Packed red cell transfusions in preterm neonates: a retrospective study Sulistio, Ivena Clairine; Delicia Rudy; Putu Siska Suryaningsih; I Wayan Bikin Suryawan
Pediatric Sciences Journal Vol. 6 No. 2 (2025): In Press Online : December 2025
Publisher : Medical Faculty of Brawijaya University, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51559/pedscij.v6i2.142

Abstract

Introduction: Preterm neonates are highly vulnerable to anemia. Packed red cell (PRC) transfusions are often necessary but must be carefully considered due to associated risks. This study aims to assess the characteristics of preterm infants who received PRC transfusions to guide safer and effective transfusion practices. Methods: This study was conducted using a retrospective descriptive approach. It included preterm neonates who received PRC transfusions, as documented in the medical records from July 2022 to March 2025. Patient characteristics, hemoglobin level, transfusion profile, and comorbidities in preterm neonates receiving PRC transfusions were evaluated. Results: The sample consisted of 52 neonates, 37 boys, and 15 girls. The gestational age of infants was mainly between 28 and <32 weeks (64,5%). Most neonates were very low birth weight, which is 53,8%. The mode of delivery was relatively similar between spontaneously and cesarean section. The average length of hospital stay was 35.27 ± 16.62 days. The initial hemoglobin level of preterm infants receiving PRC transfusions averaged 10.88 ± 1.33 g/dL. The first transfusion was typically administered at 18.10 ± 9.69 days of life. Notably, most infants (59.6%) required three or fewer transfusions. The most common comorbidity among preterm infants receiving PRC transfusions was respiratory distress syndrome (RDS) at 78.8%, followed by neonatal jaundice (53.8%) and asphyxia (40.4%). Most RDS cases (69.2%) were caused by hyaline membrane disease (HMD). Conclusion: Preterm neonates receiving PRC transfusions had a high-risk profile, underscoring the importance of individualized transfusion thresholds and close post-transfusion monitoring to improve clinical outcomes.
Co-Authors A.A Made Sucipta A.A Made Widiasa A.A. Made Sucipta A.A. Made Widiasa Adi Wirawan Alberto Afrian Alice Indradjaja, Alice Aman B Pulungan Anak Agung Made Sucipta Anak Agung Made Sucipta Anak Agung Made Sucipta Anak Agung Made Sucipta Anak Agung Made Sucipta Anak Agung Made Sucipta, Anak Agung Made Anak Agung Made Widiasa Anak Agung Made Widiasa Anak Agung Made Widiasa Andreas Eric Andrew Permana Suliarta Arimbawa * Arumndari, Runi Ayu Setyorini Mestika Mayangsari Bambang Tridjaja AAP, Bambang Tridjaja Bella Kurnia Bella Kurnia Cahaiantari, Ni Putu Elis Callista Beatrice Christina, Jessica Chyntia Conchita Christal Yasadipura Cynthia Cynthia Cynthia Cynthia Cynthia Cynthia Cynthia Jodjana Delicia Rudy Dewi, Made Ratna Doddy Kurnia Indrawan Edbert Wielim Elien Yuwono Erica Lidya Yanti Gosal, Jessica H Salim I Dewa Gede Ugrasena I Gde Doddy Kurnia Indrawan, I Gde Doddy Kurnia I Gusti Amanda Jaya I Gusti Lanang Sidiartha I Kadek Serisana Wasita I Kadek Suarca I Kadek Suarca I Made Arimbawa IB Mahendra Ida Bagus Ramajaya Sutawan, Ida Bagus Ramajaya Ida Bagus Wiadnyana IKG Suandi IM Widiaskara Imanuel Yulius Malino Jeven Reggie Santoso Jose RL Batubara Kadek Suarca Kadek Suarca Kadek Suarca, Kadek Kanthi Soraca Widiatmika Ketut Ariawati Komang Tria Anggareni Kurnia, Bella Liman, Claudia Natasha Lukman, Leni Made Cynthia Mahardika Putri Made Dwi Purnami Made Ratna Dewi Made Ratna Dewi Made Ratna Dewi Made Widiasa Mayland Margaretha Sunata Melisa Anggraeni Mustika, Putu Pradnyanita Nova Damayanti Paramerta, Ni Putu Gladys Arys Predani, Ni Luh Putu Diaswari PT Pramitha Putri Prashanti, Nyoman Ananda Putri Widyastiti, Ni Nyoman Putri, Asterisa Retno Putu Andrie Setiawan Putu Pramitha Rahayu Putu Siska Suryaningsih Putu Wahyu Dyatmika Tanaya Regina Suriadi Retno Putri, Asterisa Ruby Kurniawan Soetjiningsih Soetjiningsih Soetjiningsih Soetjiningsih Sriwaningsi, Lina Stanley Haryono Suarca, I Kadek Sukarno, Theodora Sulistio, Ivena Clairine Sunartini Sunartini Suriadi, Regina Suryaningsih, Putu Siska Susan Natalia Budihardjo sutanti sutanti Valerie Michaela Wilhelmina Widiasa - Wielim, Edbert William Grandinata Soeseno