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Journal : Cermin Dunia Kedokteran

Hubungan Antara Status Nutrisi dan Respons Imunologis pada Anak dengan HIV/AIDS di RSUD Wangaya Kota Denpasar: Hasil Penelitian Arumndari, Runi; Retno Putri, Asterisa; Liman, Claudia Natasha; Made Ratna Dewi; Suryawan, I Wayan Bikin
Cermin Dunia Kedokteran Vol 51 No 10 (2024): Infeksi
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v51i10.1097

Abstract

Introduction: HIV infection and malnutrition are strongly linked and correlated. Although the exact mechanism is unknown, malnutrition is suspected to disrupt antiretroviral (ART) drug absorption. This research is aimed at determining the relationship between nutritional status and immunological response in children with HIV/AIDS taking ART. Methods: A cross-sectional retrospective analytic study was conducted on 30 children with HIV/AIDS in the pediatric clinic at Wangaya Hospital, using medical record data. The sample was taken with purposive sampling. Nutritional status was defined as poor (weight per height [WHZ] < -2 for children <5 years old and BMI for age [BAZ] <-2 for children ≥5 years old) and good nutrition (WHZ ≥-2 and <+1 for <5 years old children and BAZ ≥-2 and <+1 for ≥5 years old). Immunological response was seen by the increase in CD4 level through a certain time span and categorized into poor (did not increase or increase below the average) and good response (increase above the average). The data was analyzed using Chi-Square. Results: There is no significant relationship between nutritional status and immunological response in children with HIV/AIDS (p = 0.660). There was an almost equal amount of each immunological response category for both good and poor nutritional status. Conclusion: This study showed no difference in immunological response among children with either good or poor nutritional status. Further research on other confounding factors that may affect immunological responses is needed.
Co-Authors A.A Made Sucipta A.A Made Widiasa A.A. Made Sucipta A.A. Made Widiasa Adi Wirawan Alberto Afrian Alice Indradjaja, Alice Aman B Pulungan Anak Agung Made Sucipta Anak Agung Made Sucipta Anak Agung Made Sucipta Anak Agung Made Sucipta Anak Agung Made Sucipta Anak Agung Made Sucipta, Anak Agung Made Anak Agung Made Widiasa Anak Agung Made Widiasa Anak Agung Made Widiasa Andreas Eric Andrew Permana Suliarta Arimbawa * Arumndari, Runi Ayu Setyorini Mestika Mayangsari Bambang Tridjaja AAP, Bambang Tridjaja Bella Kurnia Bella Kurnia Cahaiantari, Ni Putu Elis Callista Beatrice Christina, Jessica Chyntia Conchita Christal Yasadipura Cynthia Cynthia Cynthia Cynthia Cynthia Cynthia Cynthia Jodjana Dewi, Made Ratna Doddy Kurnia Indrawan Edbert Wielim Elien Yuwono Erica Lidya Yanti Gosal, Jessica H Salim I Dewa Gede Ugrasena I Gde Doddy Kurnia Indrawan, I Gde Doddy Kurnia I Gusti Amanda Jaya I Gusti Lanang Sidiartha I Kadek Serisana Wasita I Kadek Suarca I Kadek Suarca I Made Arimbawa IB Mahendra Ida Bagus Ramajaya Sutawan, Ida Bagus Ramajaya Ida Bagus Wiadnyana IKG Suandi IM Widiaskara Imanuel Yulius Malino Jeven Reggie Santoso Jose RL Batubara Kadek Suarca Kadek Suarca Kadek Suarca, Kadek Kanthi Soraca Widiatmika Ketut Ariawati Komang Tria Anggareni Kurnia, Bella Liman, Claudia Natasha Lukman, Leni Made Cynthia Mahardika Putri Made Dwi Purnami Made Ratna Dewi Made Ratna Dewi Made Ratna Dewi Made Widiasa Mayland Margaretha Sunata Melisa Anggraeni Mustika, Putu Pradnyanita Paramerta, Ni Putu Gladys Arys Predani, Ni Luh Putu Diaswari PT Pramitha Putri Prashanti, Nyoman Ananda Putri Widyastiti, Ni Nyoman Putri, Asterisa Retno Putu Andrie Setiawan Putu Pramitha Rahayu Putu Siska Suryaningsih Putu Wahyu Dyatmika Tanaya Regina Suriadi Retno Putri, Asterisa Ruby Kurniawan Soetjiningsih Soetjiningsih Soetjiningsih Soetjiningsih Sriwaningsi, Lina Stanley Haryono Suarca, I Kadek Sukarno, Theodora Sunartini Sunartini Suriadi, Regina Suryaningsih, Putu Siska Susan Natalia Budihardjo sutanti sutanti Valerie Michaela Wilhelmina Widiasa - Wielim, Edbert William Grandinata Soeseno