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All Journal Sport and Fitness Journal E-Jurnal Medika Udayana Sari Pediatri ISM (Intisari Sains Medis) : Jurnal Kedokteran Jurnal Bisnis dan Kewirausahaan Journal of the Indonesian Medical Association : Majalah Kedokteran Indonesia Indonesian Journal of Global Health research Jurnal Health Sains Journal of Educational Study International Journal of Travel, Hospitality and Events Journal of Global Pharma Technology
Putu Astawa
Departemen Ortopedi Dan Traumatologi, Universitas Udayana, Denpasar
Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Health Professions Languange, Linguistic, Communication & Media Medicine & Pharmacology Nursing Public Health Social Sciences Transportation Veterinary Other

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COMPARISON THE ANTIHYPERTENSIVE AND ANTIOXIDANT POTENTIAL BETWEEN YOUNG MAHOGANY SEEDS EXTRACT WITH MATURE MAHOGANY SEEDS EXTRACT IN RATS WITH HYPERTENSION I Wayan Putu Sutirta Yasa; Putu Astawa; I Made Jawi
Journal of Global Pharma Technology Volume 09 Issue 05
Publisher : Journal of Global Pharma Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (424.564 KB)

Abstract

Mahogany seeds have been used in the community as an antihypertensive and antioxidant. Antihypertensive and antioxidant efficacy of mature mahogany seeds has been proven in hypertensive rats. The purpose of this study was to compare the antihypertensive and antioxidant effect of mature mahogany seeds extract with young mahogany seeds extract. This study is a laboratory experimental design with pre-test and post-test design control groups, with Wistar rats as samples. Thirty rats were divided into 5 groups, each group consist of 6 rats. The control group was given saline every day as a rat model of hypertension. 1-4 treatment groups were each given NaCl and water extract of young mahogany seeds for treatment 1, the ethanol extract of young mahogany seeds as treatment 2, water extract of mature mahogany seeds as treatment 3 and ethanol extract of mature mahogany seeds as treatments 4. Dosages of extract mahogany seeds is 100 mg / head / day for 4 weeks. Before treatment, evaluation of rat blood pressure with special sphygmomanometer was held, and examination of blood MDA as a pre-test data. Further evaluation of MDA and SOD blood pressure are at the end of the study. The data were tested by ANOVA to see the difference between the groups. The results showed a decrease in blood pressure and levels of MDA were significant in all treatments (p <0.05) compared with control as well as an increase in SOD were significantly (p <0.05). The ethanol extract of mature mahogany seeds showed the most excellent antihypertensive and antioxidant properties (p <0.05). From these results, it can be concluded that the ethanol extract of mature mahogany seeds is better than young mahogany seeds extract as an antihypertensive and antioxidant in hypertensive rats.Keywords – antioxidants, hypertensive rats, mature and young mahogany seeds
Perbedaan Kadar Tumor Marker CEA dan CA 125 Antara Karsinoma Paru dengan Metastase Tulang dan Karsinoma Paru Tanpa Metastase Tulang di RSUP Sanglah Denpasar Tamzil, Kezia Aurelia; Wiratnaya, I Gede Eka; Astawa, Putu; Suyasa, I Ketut
E-Jurnal Medika Udayana Vol 11 No 11 (2022): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2022.V11.i11.P07

Abstract

Lung carcinoma is one of the most common malignancies metastasized to bone, as much as 30-40% of lung malignancies metastasize to bone in the course of the disease. Carcinoembryonic Antigen (CEA) and Cancer Antigen 125 (CA 125) are tumor markers often used to assess lung malignancy. Eventhough the character of tumor markers are less sensitive and specific, some evidence address an increase in these tumor markers in the case of lung malignancies which metastasize to bone. The purpose of this study is to prove an increase in the levels of tumor markers CEA and CA 125 in lung carcinoma with bone metastases compare to lung carcinoma without bone metastases. A cross sectional study consecutively by reviewing lung carcinoma with bone metastases and without bone metastases in patient’s medical record between 2013-2021 at RSUP Sanglah Denpasar. Of 50 lung carcinoma patients (25 patients with bone metastases and 25 patients without bone metastases), levels CEA and CA 125 tumor markers were processed using SPSS. The results showed levels of CEA were significantly higher in lung carcinoma with bone metastases (p=0,028), but levels of CA 125 were not significantly higher in lung carcinoma with bone metastases (p=0,796). The results of the study concluded that levels of CEA could be used as a valuable marker to assess lung malignancy which metastasized to bone in clinical application. Keywords: Tumor Marker Levels, CEA, CA 125, Lung Carcinoma, Bone Metastases
Marketing Mix Implementation to Increase Meeting Room Sales at The Jayakarta Lombok Beach Resort & Spa Ari Asih Purnamawati Dewi; I Putu Astawa; I Ketut Suarja; Luh Eka Armoni; Made Sudiarta; Ni Nyoman Sri Astuti
International Journal of Travel, Hospitality and Events Vol. 1 No. 3 (2022): International Journal of Travel, Hospitality and Events
Publisher : The Postgraduate School of Tourism Sahid Polytechnic

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56743/ijothe.v1i3.176

Abstract

Purpose: This research aims to determine the implementation of the marketing to the sales of meeting room in The Jayakarta Lombok Beach Resort & Spa. The problem outlined in this research is what strategy to do by the sales & marketing in increasing meeting room sales at The Jayakarta Lombok Beach Resort & Spa. Research methods: This research was conducted on the sales & marketing parties that is sales & marketing managers and sales executives at The Jayakarta Lombok Beach Resort & Spa. Analysis of the data used a qualitative descriptive analysis that elaborates information from the interviews and links with theories that support the discussion related to the marketing mix conducted by The Jayakarta Lombok Beach Resort & Spa. Results and discussion: The results obtained are the marketing mix strategy carried out at The Jayakarta Lombok Beach Resort & Spa, especially in the meeting section, which is quite good, but has a lack of promotion. The strategy implemented to increase sales are also quite effective. Implication: The development that can be done is to increase online and offline promotions and also keep communication between the sales team and consumers. Keywords: hotel, room sales, meeting room, marketing mix.
Implementation of Offline Travel Agent Promotion Model to Increase Room Occupancy Putu Wila Pradnya Paramita; I Putu Astawa; I Gusti Agung Bagus Mataram; I Putu Sudira
International Journal of Travel, Hospitality and Events Vol. 1 No. 1 (2022): International Journal of Travel, Hospitality and Events
Publisher : The Postgraduate School of Tourism Sahid Polytechnic

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56743/ijothe.v1i1.3

Abstract

ABSTRACT Purpose: The purpose of this research is to find out the implementation of a promotion model for offline travel agents at The Ritz-Carlton Bali, Indonesia, and to find out how is the influence of reservation through offline travel agents to increase room occupancy at the hotel. Research methods: The data analysis technique was carried out with qualitative analysis and quantitative analysis. Qualitative analysis is performed on primary data by interview and direct observation, to find out the promotional model carried out at hotel for offline travel agents in an effort to increase room occupancy at The Ritz-Carlton Bali. Quantitative analysis is performed on secondary data, such as classic assumption test, simple linear regression analysis, correlation analysis, t-test, and coefficient of determination by using SPSS version 25. Results and discussion: Nowadays the accommodation competition in tourism industries is very tight and The Ritz-Carlton Bali is trying to win the competition by implementing the offline travel agent promotion model in an effort to increase room occupancy rate. Implication: Based on the result of coefficient determination in this study, reservation through offline travel agent has significant influence to the room occupancy rate of 54,8% while 45,2% is influenced by other factors. Keywords: promotion, reservation, offline travel agent, room occupancy.
Sustainable MICE Event Practices: An Explorative Study Raden Ayu Trisnayoni; I Putu Astawa; I Ketut Sutama
International Journal of Travel, Hospitality and Events Vol. 1 No. 1 (2022): International Journal of Travel, Hospitality and Events
Publisher : The Postgraduate School of Tourism Sahid Polytechnic

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56743/ijothe.v1i1.9

Abstract

ABSTRACT Purpose: This research aims to provide insight into sustainable event practices implemented by Melali MICE as one of the largest event organizers in Bali, Indonesia. Research methods: The research uses a qualitative approach. The sampling used is purposive. The informant selected as a sample is considered to know the sustainability and organizing of the event. Data collection using in-depth interview methods and participatory observations of the event at Melali MICE. Results and discussion: The cost is high to meet the needs of a green environment and to meet the demands of clients who are not environmentally friendly. This makes Melali MICE less likely to implement sustainability practices in the events they organize Implication: Planning for environmentally friendly events is needed to prepare for pre-event, event and post-event consistently implement sustainability practices. Keywords: event, event organizer, MICE, environmental sustainability.
Implementation of green purchasing to support a The sustainable environment at Discovery Kartika Plaza Hotel Ni Wayan Rismayanti; I Putu Astawa; I Nyoman Rajin Aryana; I Putu Budiarta; Cokorda Istri Sri Widhari
International Journal of Travel, Hospitality and Events Vol. 2 No. 2 (2023): International Journal of Travel, Hospitality and Events
Publisher : The Postgraduate School of Tourism Sahid Polytechnic

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56743/ijothe.v2i2.253

Abstract

Purpose: This research aims to discover the application of green purchasing in Discovery Kartika Plaza Hotel to support a sustainable environment. Research methods: This study uses a qualitative descriptive method through data reduction, data presentation, and conclusions and verification. The observation technique is used in collecting data, supported by interviews and document study.   Results and discussion: The green purchasing program has been implemented correctly and by applicable rules and positively impacts the environment. Discovery Kartika Plaza Hotel will implement green purchasing; it will positively impact the surrounding environment and support a sustainable environment. Implication: Therefore, with the implementation of green purchasing, the environment around Discovery Kartika Plaza Hotel will be preserved and support a sustainable environment to meet the needs of living things in future generations. This research contributes to the science of green purchasing.   Keywords: hotel, green purchasing, sustainable environment.
Flash Sale Promotion to Increase Room Occupancy and Room Revenue at The Royal Beach Seminyak Bali Ni Kadek Hera Silawati; I Putu Astawa; I Gusti Putu Sutarma; Made Sudiarta; Ida Ayu Elistyawati
International Journal of Travel, Hospitality and Events Vol. 2 No. 2 (2023): International Journal of Travel, Hospitality and Events
Publisher : The Postgraduate School of Tourism Sahid Polytechnic

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56743/ijothe.v2i2.255

Abstract

Purpose: This research aimed to describe the implementation of flash sale promotions and the contribution of flash sales to room occupancy and room revenue at The Royal Beach Seminyak Bali (TRBS). Research methods: The research uses interviews, observation, and documentation studies on the number of room nights per month data and room revenue from flash sales data for the last three years. The data analysis technique used is descriptive statistics processed with Microsoft Excel 2013. Results and discussion: Form of the implementation of the flash sale starts with a communication plan in the form of promotions that are carried out using several platforms such as websites, mobile applications, and social media. During the execution of the flash sale, the discounted price is adjusted to the guest who is an AccorHotels member and not an AccorHotels member. Implication: Implementing the flash sale promotion was quite helpful in increasing room occupancy and room revenue by contributing the third largest reservation with an average donation of 20% for room occupancy and 18% for room revenue over the last three years.   Keywords: hotel, flash sale promotion, room occupancy, room revenue.
Pengaruh Return on Asset, Debt to Equity Ratio, dan Dividend Payout Ratio Terhadap Harga Saham Perusahaan Sub Sektor Farmasi di Bursa Efek Indonesia Periode 2020-2024 Astawa, Putu; Yuniarta, Gede Adi; Pasek, Nyoman Suadnyana
Journal of Educational Study Vol. 4 No. 2 (2024): December
Publisher : English Education Department STKIP Agama Hindu Singaraja

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Abstract

Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh Return On Asset (ROA), Debt to Equity Ratio (DER), dan Dividend Payout Ratio (DPR) terhadap harga saham perusahaan sub sektor farmasi di BEI periode 2020-2024. Populasi yang digunakan dalam penelitian ini adalah 13 perusahaan. Teknik pengumpulan sampel dalam penelitian ini menggunakan metode purposive sampling dengan beberapa kriteria sehingga diperoleh sampel sebanyak 7 perusahaan. Teknik pengumpulan data yaitu studi kepustakaan dan studi dokumen. Analisis data menggunakan analisis regresi linear berganda dengan bantuan software SPSS versi 26. Hasil analisis menunjukkan bahwa ROA tidak berpengaruh signifikan terhadap harga saham perusahaan farmasi karena memiliki nilai signifikan 0,086 > 0,05 dan t hitung sebesar 1,778 < t tabel 2,032., DER tidak berpengaruh signifikan karena memiliki nilai signifikan 0,644 > 0,05 dan t hitung sebesar 0,467 < t tabel 2,032, DPR berpengaruh signifikam karena memiliki nilai signifikan 0,000 < 0,05 dan t hitung sebesar 9,466 > t tabel 2,032, serta ROA, DER, dan DPR secara simultan berpengaruh signifikan terhadap harga saham dengan nilai signifikansi uji F sebesar 0,000 < 0,05. Nilai koefisien determinasi (R²) sebesar 0,79.
A Comparison Between the Open Posterior Approach and Arthroscopic Suture Fixation in Treating Posterior Cruciate Ligament Tibial Avulsion: A Systematic Review Kuswara, Leonardus William; Astawa, Putu; Aryana, I Gusti Ngurah Wien
Indonesian Journal of Global Health Research Vol 6 No S5 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6iS5.4360

Abstract

Posterior cruciate ligament (PCL) avulsion fractures are rare but significant injuries that can lead to knee instability and degeneration if untreated. Treatment options range from conservative management to surgical fixation. The objective of this study is to evaluate and compare the outcomes of different treatment modalities for posterior cruciate ligament (PCL) avulsion fractures, with a focus on surgical interventions, specifically open surgery and arthroscopy. Methods: A systematic literature search was conducted using the MEDLINE, EMBASE, and Cochrane Library databases from August 17, 2003 to August 17, 2023. Studies included involved patients with PCL avulsion fractures treated via arthroscopic or open fixation. Data was extracted on demographics, surgical approaches, outcomes (Lysholm scores), and complications. The Coleman methodology score was applied to assess study quality by scoring factors like study size, design, follow-up, and outcome measures, and only studies scoring ≥60 were included for data analysis. Results: Out of 1,470 studies, 12 met the inclusion criteria. Lysholm scores ranged from 85 to 100 for open approaches and 80 to 100 for arthroscopic approaches. Arthroscopic treatment showed fewer complications, such as infections or hardware irritation, while both approaches demonstrated favorable outcomes. Postoperative limitations in motion were observed in both groups, with a slightly higher incidence in the arthroscopic cohort. Conclusions: Both arthroscopic and open surgical approaches effectively treat PCL avulsion fractures, with arthroscopy showing a slight advantage in postoperative outcomes and fewer complications. However, open surgery with a small open procedure also offers satisfactory results, particularly for complex fractures.
Close Reduction Percutaneous Pinning (CRPP) versus Open Reduction Internal Fixation (ORIF) pada Fraktur Supracondylar Humerus Gartland Tipe II dan III pada Pasien Pediatri: Tinjauan Sistematis dan Meta-analisis Astawa, Putu; Maharjana, Made Agus; Adisthanaya, Surya; Putra, Made Winatra Satya; Putra, Agus Suarjaya; Savio, Sherly Desnita
Majalah Kedokteran Indonesia Vol 71 No 4 (2021): Journal of The Indonesian Medical Association - Majalah Kedokteran Indonesia, Vo
Publisher : PENGURUS BESAR IKATAN DOKTER INDONESIA (PB IDI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47830/jinma-vol.71.4-2021-389

Abstract

Introduction: Displaced supracondylar fracture in children is a challenging injury that may result in impaired functional and cosmetic outcome if not well-treated. Utilization of Closed Reduction and Percutaneus Pinning (CRPP) increased for this pathology, some authors believe ORIF results better anatomical reduction and lower rate of loss of reduction. Study aims to compare CRPP and ORIF for pediatric supracondylar humerus fracture. Method: Systematic review was conducted based on PRISMA guideline. Inclusion criteria were age less than 18 years old, comparing CRPP and ORIF for Supracondylar Humerus Fractures Gartland Type II, II.Studies of one surgical technique, Gartland type I, case reports were excluded. For meta-analysis, 6 studies were included and fixed effect model used to pool the result. In each study, mean difference (MD) with 95% confidence interval (CI) was calculated for dichotomous outcomes using Review Manager. Result: Total of 252 patients aged 0-15 years old were included. CRPP more often performed than ORIF. Satisfactory outcomes measured by Flynn’s criteria were achieved in 87.74% in CRPP and 86.73% in ORIF patient group, indicating significant difference (Heterogeneity, I2 = 23%; WMD, 1.26; 0.58 to 2.73; P =0.56). Conclusion: Current systematic review and meta-analysis suggest that for displaced supracondylar humerus fractures, ORIF offers a comparable functional and cosmetic outcome compared to CRPP.
Co-Authors Anak Agung Gede Eka Septian Utama Anak Agung Wiradewi Lestari Andy Sirada Ardo Sabir, Ardo Ari Asih Purnamawati Dewi Ari Asih Purnamawati Dewi Aryana, I Gusti Ngurah Wien Bagus Komang Satriyasa Cokorda Istri Sri Widhari Desak Made Wihandani Dimas Agusta Dwiwahyonokusuma Dwiwahyonokusuma Eka Wiratnaya Elysanti Dwi Martadiani Gede Adi Yuniarta Gede Parta Kinandana Gusti Ngurah Putra Stanu Herryanto Agustriadi Simanjuntak I Dewa Ayu Inten Dwi Primayanti I Gede Epi Paramarta I Gusti Agung Bagus Mataram I Gusti Ngurah Pramartha Wijaya Putra I Gusti Ngurah Wien Aryana I Gusti Putu Sutarma I Kadek Arya Gangga Permana I Ketut Suarja I Ketut Sutama I Ketut Suyasa I Made Ady Wirawan I Made Jawi I MADE MULIARTA . I Nyoman Adi Putra I Nyoman Adiputra I Nyoman Mangku Karmaya I Nyoman Rajin Aryana I P G. Adiatmika I Putu Adiartha Griadhi I Putu Budiarta I Putu Sudira I Wayan Putu Sutirta Yasa I Wayan Siwantara I Wayan Subawa I Wayan Suryanto Dusak Ida Ayu Elistyawati Ida Bagus Subanada Ivander Purvance Ketut Gede Mulyadi Ridia Ketut Siki Kawiyana Ketut Tirtayasa Komang Septian Sandiwidayat Kuswara, Leonardus William Luh Eka Armoni Made Bramantya Karna Made Sudiarta Made Sudiarta Made Wirabhawa Maharjana, Made Agus Muh. Ali Imron Muhammad Ali Imron Ni Kadek Hera Silawati Ni Luh Eka Armoni Ni Made Puspa Dewi Astawa Ni Nyoman Sri Astuti Ni Putu Siadi Purniti Ni Wayan Rismayanti Nyoman Indah Kusuma Dewi Nyoman Suadnyana Pasek, Nyoman Suadnyana Putra, Agus Suarjaya Putra, Made Winatra Satya Putu Satriya Yudha Permadi Putu Wila Pradnya Paramita Raden Ayu Trisnayoni Savio, Sherly Desnita Soehartono Hadi Pranata Stedy Adnyana Christian Surya Adisthanaya, Surya Susy Purnawati Tamzil, Kezia Aurelia Tjokorda Gde Bagus Mahadewa Wahyuddin, Wahyuddin Wiwekowati