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All Journal MPI (Media Pharmaceutica Indonesiana) Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan JCPS (Journal of Current Pharmaceutical Sciences) JURNAL FARMASIMED (JFM) Jurnal Pengabdian Al-Ikhlas Jurnal Pengabdian Kepada Masyarakat (Mediteg) Jurnal Jejaring Matematika dan Sains Borneo Journal Of Pharmascientech Jurnal Pengabdian UNDIKMA Jurnal Insan Farmasi Indonesia Jurnal Ilmiah Kesehatan (JIKA) Tropical Health and Medical Research Journal Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Jurnal AFAMEDIS Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Bakti Untuk Negeri Benzena Pharmaceutical Scientific Journal Jurnal Pengabdian Masyarakat Panacea Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan
Anna Khumaira Sari
Universitas Lambung Mangkurat
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Journal : Borneo Journal Of Pharmascientech

 1 
AKTIVITAS ANTIOKSIDAN DAN KADAR FENOLIK TOTAL DARI EKSTRAK DAUN KACIP FATIMAH (Labisia pumila) MENGGUNAKAN VARIASI PELARUT EKSTRAKSI Rahmatullah, Satrio Wibowo; Rizki, Muhammad Ikhwan; Sari, Anna Khumaira; Triyasmono, Liling; Normaidah, Normaidah; Lingga, Herningtyas Nautika
BORNEO JOURNAL OF PHARMASCIENTECH Vol 8 No 2 (2024): Borneo Journal of Pharmascientech
Publisher : Universitas Borneo Lestari

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.51817/bjp.v8i2.538

Abstract

Secondary metabolite content and extract characterization can be influenced by the solvent used in the extraction process. The content of phenolic compounds and antioxidant activity of Labisia pumila leaves can be influenced by solvents. This research aims to determine three extracts' antioxidant activity and total phenolic content using different solvents. Fresh L. pumila leaf samples were cleaned with running water and then dried using a drying cabinet. The dried leaves are then powdered and extracted using distilled water, 70% ethanol, and 96% ethanol. Extraction with distilled water using the infusion method and ethanol using maceration. Next, the solvent obtained was evaporated using a rotary evaporator and oven until a dry extract was obtained. Total phenolic content was determined using the UV-Vis spectrophorometric method with the Folin-Ciocalteu reagent. The standard used is error-free. Antioxidant activity was determined using the DPPH method with a UV-Vis spectrophotometer, then the IC50 value was calculated. The research showed that the total phenolic content of the distilled water extract was 6.437 ± 0.177 w/w GAE, the 70% ethanol extract was 8.377 ± 0.079 w/w GAE, and the 96% ethanol extract was 17.387 ± 0.621% w/w GAE. Antioxidant activity is known to have an IC50 value of distilled water extract of 59,716 ppm, 70% ethanol extract of 50,543 ppm, and ethanol extract of 43,520 ppm. The conclusion of the research is that of the three extracts, it is known that the antioxidant activity is the strongest, and the total phenolics are the highest in the 96% ethanol extract.
Co-Authors Ahmad Ahmad Ainun Mardiah Aisyah, Noor Akhsanul Rahmatullah Alfandani, Gina Amalia Khairunnisa Amalia Khairunnisa, Amalia Amalia Khirunnisa Amilia, Jariyah Anisa Desriyanti Aryzki, Saftia Atikah Andria Saputri Ayu Soraya Ayuchecaria, Noverda Azhara, Desiya Damayanti Buih, Putri Helena Junjung Desriyanti, Anisa Devi Eka Pratama Devia Pratiwi Dewi Kartika Dewi, Anita Ratna Difa Intannia Eka Kumalasari Elisya Fatmawati Erna Prihandiwati Erna Prihandiwati Fadlilaturrahmah Fadlilaturrahmah, Fadlilaturrahmah Fadlillaturahmah Fadlillaturahmah Febrianti, Dwi Rizki Gina Alfandani Herningtyas Nautika Lingga Isnaini, Nazhifah Izma, Hayatun Jariyah Amilia Khairunnisa Khairunnisa Khairunnisa Khairunnisa Khoerul Anwar Khoirunnisa Muslimawati Kumala, Dinna Fitria Liling Triyasmono Mahdjati Fitria Mawaddah Mawaddah Meilisa Eka Pratiwi Mia Fitriana Mochammad Maulidie Alfiannor Saputera muhammad fikri Muhammad Ikhwan Rizki Muhammad Itqan Mazdadi Muhammad Rusydi Taufik Nazhipah Isnani Noor Cahaya Normaidah, Normaidah Normila Hayati Novia Ariani Nurul huda Prasdianto Prasdianto Qadariah, Ira Rahma, Salsabila Fadiya Rahmah, Indah Noor Rahmah, Maslia RAHMANIAH RAHMANIAH Rahmatullah, Satrio Wibowo Rahmawati, Nanda Hesti Rahmi Rahmi Rakhmadhan Niah Ramadhani, Muhammad Irfan Renny Renny Risma Ayati Riza Alfian Saftia Aryzki Saftia Aryzki Sandi, Dita Ayulia Dwi Sanha, Cut Nadia Anne Saputra, Adryan Maulana Saputri, Atikah Andria Sari, Fitri Novita Shela Puzi Dina Silviana, Mega Siska Musiam Syifa Auliani Syifa Auliani Tatsbita, Inatsa Dwi Vitalika Regitasari Wahyuni, Amaliyah Winsa Wira Wijaya Yusrinie Wasiaturrahmah