Claim Missing Document
Check
Articles

Analisis Efektivitas Biaya Penggunaan Antibiotik Levofloksasin dan Azitromisin pada Pasien Penderita Corona Virus Disease-19 pada Tahun 2021 di RSUD Madani Palu: Cost-Effectiveness Analysis of Levofloxacin and Azithromycin Antibiotics Usage in Patients with Corona Virus Disease-19 in 2021 at Madani Hospital in Palu Tandah, Muhamad Rinaldhi; Ririen Hardani; Nurhafifah Wulandari Kassa; Nurul Ambianti
Media Publikasi Promosi Kesehatan Indonesia (MPPKI) Vol. 6 No. 7 (2023): July 2023
Publisher : Fakultas Kesehatan Masyarakat, Universitas Muhammadiyah Palu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56338/mppki.v6i7.3262

Abstract

Latar belakang: Corona Virus Disease 2019 (Covid-19) merupakan penyakit menular yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2 yang dapat menyebabkan gejala gangguan pernapasan akut seperti demam, batuk dan sesak napas. Dalam penatalaksanaannya, Covid-19 membutuhkan biaya yang besar. Tujuan: Penelitian ini bertujuan untuk mengetahui antibiotik manakah yang paling cost-effective antara azitromisin dan levofloksasin dalam pengobatan Corona Virus Disease-2019 periode 2021 di RSUD Madani Palu. Metode: Desain penelitian ini adalah observasional cross-sectional dengan pengambilan data pasien secara retrospektif (Januari-Desember 2021). Metode penelitian pada penelitian ini adalah purposive sampling. Analisis efektivitas biaya dilakukan dengan menghitung Average Cost Effectiveness Ratio (ACER) dan Incremental Cost Effectiveness Ratio (ICER). Hasil: Jenis kelamin laki-laki sebesar 51% dengan usia 26-45 tahun dibandingkan perempuan sebesar 49%, dan lama rawat inap terbanyak 14 hari. Biaya medis langsung pasien pengguna azitromisin lebih rendah sebesar Rp1.659.698,66 dibandingkan pasien pengguna levofloksasin sebesar Rp1.711.361,17. Nilai ACER antibiotik azitromisin sebesar Rp92.205 dan nilai ACER antibiotik levofloksasin sebesar Rp136.939. Kesimpulan: Dapat disimpulkan bahwa kelompok terapi antibiotik azitromisin lebih cost-effective dibandingkan dengan kelompok terapi antibiotik levofloksasin.
Quality of Life of Outpatients with Type 2 Diabetes Mellitus at Anutapura Hospital Diana, Khusnul; Azizah, Vina Miftahul; Hardani, Muhammad Fakhrul; Tandah, Muhamad Rinaldhi
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 11 No. 1 (2026)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v11i1.44208

Abstract

Type 2 Diabetes Mellitus (T2DM) is a chronic disease that may reduce health-related quality of life (HRQoL) because of long-term treatment complications. This study assessed HRQoL among T2DM outpatients at Anutapura Hospital and examined whether the overall HRQoL profile differed by medication group after adjustment for selected patient characteristics. A hospital-based cross-sectional study was conducted at the Internal Medicine Outpatient Clinic of Anutapura Hospital, Palu, Indonesia, from October to December 2024. Using non-probability sampling, 92 adults with T2DM were enrolled and classified into three medication groups: monotherapy oral antidiabetic drugs (OADs), combined OADs, and insulin. HRQoL was measured using the Diabetes Quality of Life Clinical Trial Questionnaire-Revised (DQLCTQ-R), which includes eight domains scored on a 0–100 scale, with higher scores indicating better HRQoL. Internal consistency was acceptable (Cronbach’s alpha = 0.82). Because several domains did not meet normality assumptions, the overall HRQoL profile was analyzed using PERMANOVA. Most respondents were female, aged 41–60 years, and had diabetes duration of less than 5 years. Across medication groups, Physical Function showed the highest scores, whereas Treatment Satisfaction tended to be the lowest. In the adjusted PERMANOVA model, medication group was not significantly associated with the overall HRQoL profile (F = 0.81, p = 0.521, R² = 0.014). In contrast, age (p = 0.016), occupation (p = 0.008), and duration of illness (p = 0.001) were significantly associated with the combined HRQoL profile. These findings suggest that HRQoL differences were more strongly related to patient characteristics than to medication group alone.