Agnes Sri Siswati
Department Of Dermatology And Venereology, Faculty Of Medicine, Public Health, And Nursing Universitas Gadjah Mada/Dr. Sardjito General Hospital, Yogyakarta 55281, Indonesia

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Perilaku Seksual Lesbian, Gay, Biseksual,Transgender, dan Risikonya terhadap Infeksi Menular Seksual Puspitasari, Monika; Susetiati, Devi Artami; Siswati, Agnes Sri
Cermin Dunia Kedokteran Vol 50 No 12 (2023): Penyakit Dalam
Publisher : PT Kalbe Farma Tbk.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55175/cdk.v50i12.968

Abstract

Lesbian, gay, bisexual, transgender (LGBT) face many gaps in sexual health aspects, including an increased risk of human immunodeficiency virus (HIV infection), sexually transmitted infections (STIs), and pregnancy. LGBT often experience social stigmatization, isolation, and rejection, even from their respective parents. Risk of STIs is related to sexual orientation, sexual anatomy, and sexual behaviour. LGBTs sexual activity may vary and with multiple partners, who are vulnerable to transmission of STIs and HIV infection. Health care providers are responsible for an open discussion regarding sexual health issues; including sexual orientation, sexual behavior, and gender identity.
Establishing the diagnosis of fournier gangrene using the modified laboratory risk indicator for necrotizing fasciitis (LRINEC) score in children: A case report Qomariah, Laily Noor; Asri Yuniarti; Triyoga; He-Yeon Asva Nafaisa; Agnes Sri Siswati
Indonesian Journal of Biomedicine and Clinical Sciences Vol 57 No 4 (2025)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v57i4.16216

Abstract

Fournier’s gangrene (FG) is a form of necrotizing fasciitis that affects the genital and perineal areas. It is rare case in children and is often difficult to diagnose early, contributing to high morbidity and mortality. Prompt diagnosis and aggressive management are essential to reduce life-threatening complications. We report 2 mo. male infant presented with fever and an abrupt onset of rapidly spreading erythematous rash. Laboratory examinations showed leukocytosis, anemia, neutrophilia, hyponatremia, and elevated C-reactive protein (CRP) levels. An evaluation was performed using the pediatric laboratory risk indicator for necrotizing fasciitis (P-LRINEC), a modified version of the LRINEC score. The patient had a total score of 10, indicating a high risk of necrotizing fasciitis. The patient underwent immediate debridement and empirical antibiotic therapy. A 2 wk post-therapy evaluation showed significant clinical improvement. Fournier’s gangrene in children often resembles other skin infections, making early diagnosis difficult. The 3 main characteristics of FG are sudden onset, rapid progression, and lack of a clear specific cause. The P-LRINEC score is a diagnostic tool that can aid in the early detection of FG in children. This case highlights the importance of early recognition and management of Fournier’s gangrene in children using the P-LRINEC score, which is more appropriate for pediatric patients, to enable timely intervention. Increased clinical awareness and further validation through larger-scale studies are needed.