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All Journal Jurnal Gizi Journal of Nutrition College Jurnal Kesehatan Masyarakat Andalas (Andalas Journal of Public Health) Jurnal Dampak JURNAL KESEHATAN LINGKUNGAN (Journal of Environmental Health) Nutri-Sains: Jurnal Gizi, Pangan dan Aplikasinya Public Health of Indonesia Jurnal Gizi Klinik Indonesia Amerta Nutrition JUARA : Jurnal Olahraga Jurnal Sehat Mandiri Sport and Nutrition Journal Jurnal Teknologi Kesehatan International Journal of Disaster Management Jurnal Pengabdian Masyarakat Cendikia Jenius Poltekita: Jurnal Ilmu Kesehatan Proceeding International Health Conference
Defriani Dwiyanti, Defriani
Politeknik Kesehatan Kemenkes Padang
Humanities Biochemistry, Genetics & Molecular Biology Decision Sciences, Operations Research & Management Dentistry Earth & Planetary Sciences Education Engineering Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Pengaruh Pemberian Sinbiotik, Probiotik, dan Prebiotik terhadap Depresi, Stres, dan Mood pada Orang Dewasa: Systematic Review dan Meta-Analisis: Effects of Synbiotic, Probiotic, and Prebiotic Supplementation on Depression, Stress, and Mood in Adults: A Systematic Review and Meta-Analysis Habibi, Nur Ahmad; Gusnedi, Gusnedi; Nindrea, Ricvan Dana; Hasniyati, Rina; Afriza, Renita; Rusydi, Riska; Yuska, Defniwita; Darningsih, Sri; Zulkifli, Zulkifli; Ismanilda, Ismanilda; Handayani, Marni; Utami, Citra Tristi; Umar, Hermita Bus; Dwiyanti, Defriani; Yuniritha, Eva
Amerta Nutrition Vol. 9 No. 1SP (2025): AMERTA NUTRITION SUPPLEMENTARY EDITION Special 5th Amerta Nutrition Conferenc
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v9i1SP.2025.420-430

Abstract

Background: Psychobiotics, including probiotics, prebiotics, and synbiotics, have been proposed to improve mental health through modulation of the gut–brain axis. However, findings from randomized controlled trials (RCTs) remain inconsistent, Objectives: To systematically review and synthesize evidence on the effects of probiotics, prebiotics, and synbiotics on depression, stress, and mood in adult populations. Methods: A comprehensive search was conducted in PubMed, yielding 531 articles, of which 14 RCTs met the inclusion criteria. Risk of bias was assessed using the Cochrane Risk of Bias Tool. Meta-analyses were performed using both fixed- and random-effects models in RevMan. The study protocol was registered in PROSPERO (CRD420251103338). Discussions: Ten RCTs (n = 881) assessing depression did not show consistent benefits (SMD = –0.72; 95% CI: –1.42 to –0.01; p-value = 0.05; I² = 96%). Six RCTs (n = 444) evaluating stress also showed non-significant effects (MD = –1.35; 95% CI: –3.70 to 1.01; p-value = 0.26; I² = 73%). Conversely, six RCTs (n = 376) demonstrated significant improvements in mood (MD = 0.73; 95% CI: 0.25 to 1.20; p-value = 0.003; I² = 75%). Meta-regression indicated that larger sample sizes were associated with more consistent improvements in mood (p-value = 0.04). Sensitivity analyses confirmed the stability of the findings, and no evidence of publication bias was detected. Conclusions: Probiotic, prebiotic, and synbiotic supplementation may provide beneficial effects on mood and could serve as a potential nutritional intervention to enhance psychological health. However, effects on depression and stress inconsistent.
Multi-Criteria Analysis to Map Malnutrition Vulnerability to The Impact of Climate Change in West Sumatra, Indonesia Defriani Dwiyanti; Barlian, Eri; Razak, Abdul; Dewata, Indang; Syah, Nurhasan; Siregar, Dewi Rahmadani
Public Health of Indonesia Vol. 12 No. 1 (2026): January - March
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v12i1.1203

Abstract

Background: Indonesia is the world's second most disaster-prone country and faces significant climate change impacts. West Sumatra has high malnutrition, moderate food insecurity, and disaster risk. Mapping climate vulnerability is critical for mitigation and adaptation. Objective: Building on this need, this study aims to map the vulnerability of malnutrition due to climate change in West Sumatra Province, Indonesia. Methods: The research employed an analytical descriptive approach, utilizing secondary data from official agencies. Sources included the Central Statistics Agency of West Sumatra Province, the Meteorology, Geophysics and Climatology Agency, the Indonesian Nutrition Status Survey, and the Indonesian Health Survey from 2019 to 2023. The data covered three vulnerability indicators: exposure, sensitivity, and adaptive capacity. These were analyzed by the Weighted Product method and classified into five categories of vulnerability (very low, low, medium, high, very high) using the Equal Interval method. Results were presented as thematic maps using ArcGIS software. Results: The analysis revealed that 5.3% of areas had very high vulnerability to malnutrition linked to climate change. Meanwhile, 10.5% were high, 26.3% medium, 42.1% low, and 15.8% very low. The coastal regions of Mentawai, West Pasaman, and South Coast were the most vulnerable. Vulnerability was determined by exposure, sensitivity, and adaptive capacity. Regions with higher vulnerability had greater sensitivity and lower adaptive capacity. Regions with lower vulnerability showed better adaptive capacity. Conclusions: Based on the findings, it is recommended to prioritize areas with high and very high vulnerability. Efforts should be focused on improving access to health and nutrition services, empowering women in household food decisions, and strengthening food systems to strengthen regional adaptive capacity. Keywords: mapping; vulnerability; malnutrition; climate change
Co-Authors Abdul Razak Alsri Windra Doni Amos, John Burhan Muslim Citra Maharani Darwel, Darwel Defniwita Yuska Edmon Edmon Eri Barlian Eva Yuniritha, Eva Gusnedi Gusnedi Hamam Hadi Hamam Hadi Handayani, Marni Hasneli, Hasneli Hasneli, Hasneli Heppi Sasmita Hermita Bus Umar Indang Dewata Irma Eva Yani Ismanilda, Ismanilda Iswanelly Mourbas Juanda Juanda Juanda Juanda Kasmiyetti, Kasmiyetti Khairunnisa Khairunnisa Kurnia, Dilla Indah LINDAWATI Mahaza Muslim, Burhan Nindrea, Ricvan Dana Nur Ahmad Habibi Renita Afriza Rina Hasniyati Riviwanto, Muchsin Rusydi, Riska Sari, Adira Mustika Siregar, Dewi Rahmadani Sri Darningsih Sugriarta, Evino Sukapti Sukapti Susetyowati Utami, Citra Tristi Vebby Amellia Edwin Wijayantono Wiwi Febriani Yohandrey, Febry Zulfah Rahmah Zulfah Rahmah Zulkifli Zulkifli