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Pengaruh Pemberian Sinbiotik, Probiotik, dan Prebiotik terhadap Depresi, Stres, dan Mood pada Orang Dewasa: Systematic Review dan Meta-Analisis: Effects of Synbiotic, Probiotic, and Prebiotic Supplementation on Depression, Stress, and Mood in Adults: A Systematic Review and Meta-Analysis Habibi, Nur Ahmad; Gusnedi, Gusnedi; Nindrea, Ricvan Dana; Hasniyati, Rina; Afriza, Renita; Rusydi, Riska; Yuska, Defniwita; Darningsih, Sri; Zulkifli, Zulkifli; Ismanilda, Ismanilda; Handayani, Marni; Utami, Citra Tristi; Umar, Hermita Bus; Dwiyanti, Defriani; Yuniritha, Eva
Amerta Nutrition Vol. 9 No. 1SP (2025): AMERTA NUTRITION SUPPLEMENTARY EDITION Special 5th Amerta Nutrition Conferenc
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/amnt.v9i1SP.2025.420-430

Abstract

Background: Psychobiotics, including probiotics, prebiotics, and synbiotics, have been proposed to improve mental health through modulation of the gut–brain axis. However, findings from randomized controlled trials (RCTs) remain inconsistent, Objectives: To systematically review and synthesize evidence on the effects of probiotics, prebiotics, and synbiotics on depression, stress, and mood in adult populations. Methods: A comprehensive search was conducted in PubMed, yielding 531 articles, of which 14 RCTs met the inclusion criteria. Risk of bias was assessed using the Cochrane Risk of Bias Tool. Meta-analyses were performed using both fixed- and random-effects models in RevMan. The study protocol was registered in PROSPERO (CRD420251103338). Discussions: Ten RCTs (n = 881) assessing depression did not show consistent benefits (SMD = –0.72; 95% CI: –1.42 to –0.01; p-value = 0.05; I² = 96%). Six RCTs (n = 444) evaluating stress also showed non-significant effects (MD = –1.35; 95% CI: –3.70 to 1.01; p-value = 0.26; I² = 73%). Conversely, six RCTs (n = 376) demonstrated significant improvements in mood (MD = 0.73; 95% CI: 0.25 to 1.20; p-value = 0.003; I² = 75%). Meta-regression indicated that larger sample sizes were associated with more consistent improvements in mood (p-value = 0.04). Sensitivity analyses confirmed the stability of the findings, and no evidence of publication bias was detected. Conclusions: Probiotic, prebiotic, and synbiotic supplementation may provide beneficial effects on mood and could serve as a potential nutritional intervention to enhance psychological health. However, effects on depression and stress inconsistent.
Multi-Criteria Analysis to Map Malnutrition Vulnerability to The Impact of Climate Change in West Sumatra, Indonesia Defriani Dwiyanti; Barlian, Eri; Razak, Abdul; Dewata, Indang; Syah, Nurhasan; Siregar, Dewi Rahmadani
Public Health of Indonesia Vol. 12 No. 1 (2026): January - March
Publisher : YCAB Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36685/phi.v12i1.1203

Abstract

Background: Indonesia is the world's second most disaster-prone country and faces significant climate change impacts. West Sumatra has high malnutrition, moderate food insecurity, and disaster risk. Mapping climate vulnerability is critical for mitigation and adaptation. Objective: Building on this need, this study aims to map the vulnerability of malnutrition due to climate change in West Sumatra Province, Indonesia. Methods: The research employed an analytical descriptive approach, utilizing secondary data from official agencies. Sources included the Central Statistics Agency of West Sumatra Province, the Meteorology, Geophysics and Climatology Agency, the Indonesian Nutrition Status Survey, and the Indonesian Health Survey from 2019 to 2023. The data covered three vulnerability indicators: exposure, sensitivity, and adaptive capacity. These were analyzed by the Weighted Product method and classified into five categories of vulnerability (very low, low, medium, high, very high) using the Equal Interval method. Results were presented as thematic maps using ArcGIS software. Results: The analysis revealed that 5.3% of areas had very high vulnerability to malnutrition linked to climate change. Meanwhile, 10.5% were high, 26.3% medium, 42.1% low, and 15.8% very low. The coastal regions of Mentawai, West Pasaman, and South Coast were the most vulnerable. Vulnerability was determined by exposure, sensitivity, and adaptive capacity. Regions with higher vulnerability had greater sensitivity and lower adaptive capacity. Regions with lower vulnerability showed better adaptive capacity. Conclusions: Based on the findings, it is recommended to prioritize areas with high and very high vulnerability. Efforts should be focused on improving access to health and nutrition services, empowering women in household food decisions, and strengthening food systems to strengthen regional adaptive capacity. Keywords: mapping; vulnerability; malnutrition; climate change
Analisis Menu Dilihat dari Citarasa, Variasi Menu, dan Besar Porsi Makanan yang Disajikan Hidayatullah, Nadia; Yani, Irma Eva; Dwiyanti, Defriani
Jurnal Sehat Mandiri Vol 21 No 1 (2026): Jurnal Sehat Mandiri, Volume 21, No.1 Juni 2026
Publisher : Poltekkes Kemenkes Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33761/jsm.v21i1.2058

Abstract

Poorly managed food organization can affect the quality of the menu served, especially in terms of flavor, variety, and portion size. This study aims to describe the food menu at the Yayasan Bening Nurani (YABNI) Padang Foster Home in 2025 in terms of flavor, menu variety, and portion size. This study used a quantitative approach with a cross sectional design conducted in July-August 2024. The sample consisted of 48 foster children. Data collection was carried out through observation, interviews, questionnaires, and weighing of food ingredients for 7 days. Data were analyzed univariately and presented in frequency distribution and percentage. The results showed that 62.5% of foster children did not like the taste of food and 60.4% rated the appearance of food as unattractive. A total of 54.17% stated that food ingredients and processing were not varied, and 52.08% stated that the color and taste of food did not vary. In addition, the portions of staple foods, animal side dishes, vegetable side dishes, vegetables, and oil are not in accordance with the daily meal recommendations. It can be concluded that the flavors, menu variations, and food portions do not meet the recommended standards. Therefore, it is recommended that institutions improve food management by paying attention to flavor, variety of ingredients and processing, and portions that meet the needs of foster children.