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All Journal Current Biochemistry Jurnal Pendidikan dan Pembelajaran Kimia (JPPK) SELAPARANG: Jurnal Pengabdian Masyarakat Berkemajuan MATRIK : Jurnal Manajemen, Teknik Informatika, dan Rekayasa Komputer Jurnal Pengabdian Magister Pendidikan IPA JURNAL PENELITIAN PERAWAT PROFESIONAL Jurnal Kolaboratif Sains Jurnal Ilmiah Berkala: Sains dan Terapan Kimia Prisma Sains: Jurnal Pengkajian Ilmu dan Pembelajaran Matematika dan IPA IKIP Mataram Jurnal Medical Laboratory Jurnal Ilmiah Pengabdian dan Inovasi Jurnal Multidisiplin Sahombu PCJN Pharmaceutical and Clinical Journal of Nusantara BIOCITY: Journal of Pharmacy Bioscience and Clinical Community Pengabdian Kepada Masyarakat Bidang Teknologi dan Sistem Informasi Jurnal Wicara Desa Indonesian Journal of Health Research Innovation
Nurul Indriani
Universitas Bumigora, Mataram, Indonesia
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Journal : BIOCITY: Journal of Pharmacy Bioscience and Clinical Community

 1 
Aktivitas Antioksidan Ekstrak Metanol dan Fraksi N-Heksan-Etil Asetat Buah Paprika Merah (Capsicum annuum L.) Nur Anisah; Warsi Warsi; Muhammad Eka Putra Ramandha; Widani Darma Isasih; Rizqa Inayati; Nurul Indriani
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 1 No 1 (2022): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v1i1.2459

Abstract

Buah paprika merah (Capsicum annuum L.) mengandung diantaranya adalah vitamin E, vitamin C, karotenoid, dan kapsaisinoid yang dapat digunakan sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan pada ekstrak metanol dan fraksi n-heksan-etil asetat buah paprika merah. Buah paprika merah segar diekstraksi dengan metode maserasi menggunakan pelarut metanol teknis kemudian difraksinasi secara bertingkat menggunakan pelarut n-heksan-dietil eter, hasil fraksi tidak larut n-heksan-dietil eter kemudian difraksinasi kembali menggunakan pelarut n-heksan-etil asetat. Fraksi n-heksan-etil asetat diuji secara kualitatif terhadap senyawa karotenoid yaitu β-karoten dengan uji KLT menggunakan fase diam silika gel F254 dan fase gerak metanol: aseton (1:1). Uji kuantitatif aktivitas antioksidan dilakukan dengan metode penangkapan radikal DPPH dengan parameter nilai IC50. Nilai IC50 selanjutnya dianalisis dengan menggunakan SPSS versi 20. Hasil uji kualitatif menunjukkan bahwa ekstrak metanol dan fraksi n-heksan-etil asetat mengandung senyawa β-karoten. Aktivitas antioksidan ekstrak metanol, fraksi n-heksan-etil asetat, dan standar β-karoten memiliki nilai IC50 berturut-turut sebesar 307,91, 281,69, dan 81,26 μg/mL. Berdasarkan hasil statistik, nilai IC50 fraksi n-heksan-etil asetat lebih kecil signifikan apabila dibandingkan dengan ekstrak metanol buah paprika merah. Namun lebih besar apabila dibandingkan dengan standar β-karoten. Fraksi n-heksan-etil asetat memiliki aktivitas antioksidan yang lebih poten apabila dibandingkan dengan ekstrak metanol buah paprika merah. Namun kurang poten apabila dibandingkan dengan standar β-karoten.
Aktivitas Antioksidan Ekstrak Metanol dan Fraksi N-Heksan-Etil Asetat Buah Paprika Merah (Capsicum annuum L.) Anisah, Nur; Warsi, Warsi; Ramandha, Muhammad Eka Putra; Isasih, Widani Darma; Inayati, Rizqa; Indriani, Nurul
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol. 1 No. 1 (2022): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v1i1.2459

Abstract

Buah paprika merah (Capsicum annuum L.) mengandung diantaranya adalah vitamin E, vitamin C, karotenoid, dan kapsaisinoid yang dapat digunakan sebagai antioksidan. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan pada ekstrak metanol dan fraksi n-heksan-etil asetat buah paprika merah. Buah paprika merah segar diekstraksi dengan metode maserasi menggunakan pelarut metanol teknis kemudian difraksinasi secara bertingkat menggunakan pelarut n-heksan-dietil eter, hasil fraksi tidak larut n-heksan-dietil eter kemudian difraksinasi kembali menggunakan pelarut n-heksan-etil asetat. Fraksi n-heksan-etil asetat diuji secara kualitatif terhadap senyawa karotenoid yaitu β-karoten dengan uji KLT menggunakan fase diam silika gel F254 dan fase gerak metanol: aseton (1:1). Uji kuantitatif aktivitas antioksidan dilakukan dengan metode penangkapan radikal DPPH dengan parameter nilai IC50. Nilai IC50 selanjutnya dianalisis dengan menggunakan SPSS versi 20. Hasil uji kualitatif menunjukkan bahwa ekstrak metanol dan fraksi n-heksan-etil asetat mengandung senyawa β-karoten. Aktivitas antioksidan ekstrak metanol, fraksi n-heksan-etil asetat, dan standar β-karoten memiliki nilai IC50 berturut-turut sebesar 307,91, 281,69, dan 81,26 μg/mL. Berdasarkan hasil statistik, nilai IC50 fraksi n-heksan-etil asetat lebih kecil signifikan apabila dibandingkan dengan ekstrak metanol buah paprika merah. Namun lebih besar apabila dibandingkan dengan standar β-karoten. Fraksi n-heksan-etil asetat memiliki aktivitas antioksidan yang lebih poten apabila dibandingkan dengan ekstrak metanol buah paprika merah. Namun kurang poten apabila dibandingkan dengan standar β-karoten.
Analisis Profil Pemberian Obat Golongan Proton Pump Inhibitor (PPI) pada Penanganan Gastritis Amalia, Aini; Indriani, Nurul; Kresnapati, I Nyoman Bagus Aji
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 2 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i2.5339

Abstract

Gastritis is an inflammation of the gastric mucosa that is commonly found in healthcare facilities, including Tripat Regional General Hospital. One of the main therapies for gastritis is the use of Proton Pump Inhibitor (PPI) medications, which work by reducing gastric acid secretion. This study aims to understand the profile of PPI administration in gastritis patients at Tripat Regional General Hospital in 2023. This study uses a retrospective descriptive approach, collecting data from the medical records of outpatient and inpatient patients in 2023. The results show that the number of gastritis cases reached 574 patients. The most commonly used PPI medication is omeprazole (38.4%), with the most frequently prescribed dosage being 20 mg (52.3%), and the most common administration frequency is once a day (93.0%). The conclusion of this study indicates that the use of PPI in gastritis patients at Tripat Regional General Hospital is mostly in accordance with guidelines
Analisis Tingkat Kepatuhan Minum Obat terhadap Kejadian Kekambuhan pada Pasien Gastroesophageal Reflux Disease (GERD) Rasyid, M. Gazali Abdul; Indriani, Nurul; Kresnapati, I Nyoman Bagus Aji
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 2 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i2.5367

Abstract

:  Gastroesophageal Reflux Disease (GERD) is a digestive tract disorder with a rising prevalence both globally and in Indonesia. Recurrence among GERD patients is often linked to medication adherence. This study aims to analyze the relationship between medication adherence and recurrence in GERD patients at RSUD Tanjung in 2024. A qualitative method was used, with data collected from medical records of patients undergoing regular treatment. A total of 84 patients were selected using Slovin's formula from a population of 538 patients. Data were analyzed descriptively and followed by Chi-Square, Homogeneity, and ANOVA tests. The results showed that the recurrence rate among GERD patients was 66%, while the medication adherence rate was only 34%. The Chi-Square test showed no significant relationship between gender and visit frequency. The Homogeneity test indicated that the data variances among groups were homogeneous, and the ANOVA test showed a significant difference based on visit frequency. The study concludes that medication adherence among GERD patients at RSUD Tanjung remains low, contributing to a high recurrence rate. Educational and interventional efforts are needed to improve patient adherence to therapy in order to reduce GERD recurrence rates.
Analisis Kejadian Dispepsia terhadap Faktor Pemicunya Saputri, Syarifa Anita; Indriani, Nurul; Kresnapati, I Nyoman Bagus Aji
Biocity Journal of Pharmacy Bioscience and Clinical Community Vol 3 No 2 (2025): Biocity: Journal of Pharmacy Bioscience and Clinical Community
Publisher : Department of Pharmacy, Bumigora University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30812/biocity.v3i2.5383

Abstract

Analysis of Dyspepsia Incidence Against Trigger Factors in Patients at the Narmada  Health Center. Dyspepsia is a common condition characterized by discomfort or pain in the upper abdomen, and can affect a person's quality of life and have a negative impact on the sufferer's productivity. The purpose of this study was to analyze the incidence of dyspepsia against its triggering factors in Narmada Health Center. This study used a quantitative method with a cross-sectional research design, with a questionnaire instrument that was valid (0.612 - 0.951) and reliable (> 0.90). Results The prevalence of dyspepsia in this study was 164 people based on data from the Narmada Health Center. The frequency of knowledge levels, consuming frogs, exercising on an empty stomach, smoking habits, and the begibung tradition did not show a significant relationship with the incidence of dyspepsia in the community (p-value> 0.05). Meanwhile, the incidence of dyspepsia has a significant relationship with the frequency of consumption of spicy foods, sour foods, fatty foods, raw foods, consuming coffee with a value (p-value <0.05). The conclusion of this study is that the frequency of consumption of spicy foods, sour foods, fatty foods, raw foods, consuming caffeine and drugs are risk factors for the incidence of dyspepsia in the patients at Narmada Health centers
Co-Authors Adriyan Suhada Aini, Niza Husnul Aini, Zahratul Ajeng Dian Pertiwi, Ajeng Dian Aji Kresnapati, Nyoman Bagus Amalia, Aini Anam, M Khairul Anisah, Nur Anjani, Desak Sri Ayu Apriani , Nurul Aulia Aprilia, Dwi Ayu Awang, Kevin Aditya Agusto Ayudia Cipta Khairani Ayudia Cipta Khairani Azizah, Nur Shafa Azkia, Tina Imro’atun Baiq Yulia Hasni Pratiwi Bq Sari Hidayatullah Dinda Febriani Eka Nurul Qomaliyah Estiana Fardani, Roushandy Asri Farida Ariani Fitri Apriliany, Fitri Hafiz, Lalu Muhamad Fajri Hendri Yogi Pratama I Made Suartika Ibrahim, Muhammad Rivani Idham Halid Inayati, Rizqa Islamiyati, Ricka Ispaniah Jannaturroyani Jundillah, Muhammad Labib Kresnapati, I Nyoman Bagus Aji Lalu Zulkifli M. Irpan Siswandi Mia Ariasti Muchsin, Lalu Busyairi Mudawil Qulub Muhamad Azwar Muhamad Irham, Muhamad Muhammad Eka Putra Ramandha Muhsin, Lalu Busyairi Ni Nyoman Ariwidiani Ni Putu Rainita Mileniaputri Novianty, Wanda Nur Anisah Nurfajrin Aliyatri Paturrahmi, Wilda Marta Pauzan Pauzan, Pauzan Ramadhani, Muhammad Wisda Pradja Rasyid, M. Gazali Abdul Ratulangi, Wulan Ratia Rizky Tri Septiawan Rizqa Inayati Rohma, Atika Rosnalia Widyan Sahra, Baiq Yatmi El Saputri, Syarifa Anita Satria Wirananda, I Nengah Sekar Ningrat, Lalu Nune Sofya, Sri Winarni Sri Winarni Sofya Syahria Ulya, Tuhfatul Utami, Evi Fatmi Utami, Nadia Fitri Warsi Warsi Warsi Warsi Widani Darma Isasih Yodisya, Raihan Yodita, Zahrawana Putri