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Systematic Review: Analysis of the Relationship Between Benzene Exposure and the Incidence of Anemia Among Workers Ayudhia Rachmawati; Danang Wahansa Sugiarto
Mulawarman International Conference on Tropical Public Health Vol. 2 No. 2 (2025): The 4th MICTOPH
Publisher : Faculty of Public Health Mulawarman University, Indonesia

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Abstract

Background : Benzene is a volatile organic compound widely used in industrial sectors such as petrochemicals, paints, solvents, and the manufacture of rubber and plastics. Continuous exposure to benzene vapor in occupational settings can disrupt the hematopoietic system, leading to anemia. Objective : This review was systematically conducted to examine the relationship between benzene exposure and the incidence of anemia among industrial workers. Research Methods/ Implementation Methods : The method followed the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). Literature sources were obtained from three databases: PubMed, Wiley Online Library, and Science Direct, with publication years limited to 2020–2025. Included articles were English-language, full-text publications that reported observational or experimental studies assessing the hematopoietic effects of benzene leading to anemia. Results : The search yielded three studies meeting the inclusion criteria, all conducted in China and Iran. The main findings indicated that low-level benzene exposure (<1 ppm) significantly reduced erythrocyte and leukocyte counts. Additionally, genetic variations in the ATM and H2AX genes were associated with increased susceptibility to hematological abnormalities among individuals exposed to BTEX (benzene, toluene, ethylbenzene, xylene). Elevated expression of microRNA Let-7e-5p was suggested to play a role in disrupting apoptosis and cell proliferation in bone marrow, contributing to hematopoietic dysfunction. Conclusion/Lesson Learned : Overall, the reviewed evidence demonstrates that benzene’s hematotoxic effects can occur even at very low exposure levels. These findings highlight the importance of workplace environmental monitoring, consistent use of personal protective equipment, and routine blood examinations to enable early detection of anemia resulting from chronic benzene exposure
Analysis Environmental Factors of Diarrhea in East Kalimantan Province Based on a Large-Scale Survey Muhammad Aidil Fitrah; Ayudhia Rachmawati; Vivi Filia Elvira; Morrin Choirunnisa Thohira; Syamsir Syamsir
Mulawarman International Conference on Tropical Public Health Vol. 2 No. 2 (2025): The 4th MICTOPH
Publisher : Faculty of Public Health Mulawarman University, Indonesia

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Background : Diarrhea remains a global public health problem with high morbidity and mortality rates. Environmental conditions such as poor sanitation infrastructure and hygiene practices have the potential to increase the risk of diarrhea. Objective : This study aims to analyze the relationship between environmental factors and the incidence of diarrhea in East Kalimantan Province based on big data from the 2023 Indonesian Health Survey (SKI). Research Methods/ Implementation Methods : This study employed a cross-sectional design using secondary data from 15,854 SKI respondents. Variables included gender, education, drinking water sources, water quality and treatment, storage containers, wastewater disposal, waste management, sanitation access, and hygiene practices. Data were analyzed using Chi-square and logistic regression to determine independent environmental factors influencing diarrhea incidence. Results : The prevalence of diarrhea was 2.1%. Bivariate analysis showed a significant association between the incidence of diarrhea and education (p=0.001), drinking water source (p=0.003), physical quality of drinking water (p=0.000), raw water source (p=0.012), waste management (p=0.002), and sanitation hygiene (p=0.000). In the models of multivariable logistic regression analysis, it was found that physical quality of drinking water (AOR=2.058; p<0.001), level of education (AOR=2.008; p<0.001), and waste management (AOR=1.276; p=0.032) were the main determinants of diarrhea incidence. Conclusion/Lesson Learned : Poor drinking water quality, low levels of education, and inadequate waste management increase the risk of diarrhea in East Kalimantan. Efforts to improve water quality, environmental health education, and household-based waste management need to be strengthened to reduce the incidence of diarrhea.
Assessment of Housing Conditions and Clean Water Sources as Determinants of Environmental Health in Rural Areas of Tenggarong Seberang District, Indonesia Abdul Ridho Dhafa Risqillah; Tirsa Aulia Juniarti; Siti Fadilah Harun; Ashri Rahmaya Nur; Angela Lionthin Salsa; Putri Fitria Listi; Ayudhia Rachmawati
Mulawarman International Conference on Tropical Public Health Vol. 2 No. 2 (2025): The 4th MICTOPH
Publisher : Faculty of Public Health Mulawarman University, Indonesia

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Abstract

Background : Community health status is strongly influenced by environmental factors, particularly housing conditions and access to clean water. Poor environmental quality increases the risk of environmentally related diseases such as diarrhea, skin infections, and acute respiratory infections (ARI). Objective : This study aimed to assess the physical quality of houses and sources of clean water as a basis for improving environmental health in rural areas. Research Methods/ Implementation Methods : A quantitative descriptive design with univariate analysis was employed in Bukit Pariaman Village, Suka Sari Hamlet, Tenggarong Seberang District. Data were collected through field observation, structured interviews, and questionnaires involving 57 household heads. Results : Findings revealed that 84.2% of houses had adequate ventilation and 73.7% had permanent walls, whereas 26.3% lacked sufficient natural lighting. Approximately 96.5% of households accessed clean water through piped water systems; however, 33.3% stored water in uncovered containers and 12.3% had wells located less than 10 meters from septic tanks, posing contamination risks. In addition, 70.2% of households owned private latrines, while 29.8% used shared facilities. Conclusion/Lesson Learned : Most households met the criteria for healthy housing, yet improvements are needed in lighting, water source distance, and water storage practices to minimize the risk of environmentally related diseases.
Co-Authors Abdul Ridho Dhafa Risqillah Abdullah, Ahmad Fadhlil Azhim Adelina Butar Butar, Bellinda Afifah Bidayah Al Mubarok, Ahmad Zakki Alifka Ramadani, Sela Amalia, Syaumi Nur Amirah, Nada Anastasya, Melisa Angela Lionthin Salsa Aprilia Sarwani, Audi Arnelya Natasha Lumadyo Arsyina, Lia Ashri Rahmaya Nur Ayu Amalia Rahmi Azzahra, Gasella Aurelia Badrah, Sitti Bambang Wispriyono Blego Sedionoto, Blego Cica Rahmawati Daffi Maulany, Ahmad Danang Wahansa Sugiarto Danang Wahansa Sugiarto Desy Hajizah Dhafin, Ahmad Dortua Lince Sidabalok Ellanda Yunisa Elvira, Vivi Filia Erna Fidyatun Erri Larene Safika Ervini Ervini Evi Martha Fauzi , Fahri Hasbiah Hutabarat, Fiery Indra Christian Inayah, Andini Nur Tsabita Irene Fidela Fuan Taruk Padang Irfansyah Baharuddin Pakki Jenissa, Abel khadri, Albrian Khairunnisa, Nur Baiti Marsanda, Siti Masruroh1,2, Ah Yusuf3 , Nikmatur Rohmah4, Irfansyah Baharudin Pakki5 , Anita Dewi Prahastuti Prasojo6 , Qurnia Andayani1 , *Agung Dwi Laksono7 Masyhuri Majiding, Chaidir Misnawati Morrin Choirunnisa Thohira Muh Amri Arfandi Muhammad Aidil Fitrah MUHAMMAD RIZAL Munawati Banne La’bi Muzaqi , Muhammad Choirul N. Nurjanah Nabilla Nabilla Nabillah, Nur Annisa Nada, Nur Nazliyatun Nur, Muhammad Roihan Nurhidayat , Rifki Nurilmi, Alifani Siti Nurmala Indika Oniek Lestari, Oniek Pardilla , Irva Alrisyaduhita Pradita, Adelia Putri Puri Handayani Pusparini, Ryzkita Puspita , Shindy Putra, Umar Farauk Eka Putri Fitria Listi Rachmadani, Nova Sri Rahma Nabilla, Hanifah Rahmadani, Tiara Fitri Rahmadina, Andi Nur Nayla Ramadanti, Nadiyah Karin Ramadhani, Irma Ravli Saputra, Ardi Redi Yudha Irianto Riagil , Julia Putri Ridho Abdilah, Muhammad Noval Riyan Ningsih Rosandini , Adella Nadhif Rugayyah, Syarifah S Siswanto Sabrinanova, Monanda Sartika, Afnila Sasmita, Khania Fazza Siti Fadilah Harun Siti Nuraini Sitohang, Yohana Sri Rahmayanti, Sri Sugiarto, Danang Wahansa Suleman, Angellia Syamsir Syamsir Syamsir Syamsir Syamsir Syamsir Tirsa Aulia Juniarti Tirsa Tonapa Umhersuny, Brithnay Vensca Valencia Utami, Reza Evelin Vionita, Wanda Dila Virgil, Aron Natala Vivi Filia Elvira Wardhani, Amelia Yunita Wulandari, Tiara Sahfitri Wulandari, Yanti Nur Yumanda , Inayah Dwi Setia Zalzabila Maharani, Siti Malikha